@spiceErrorCheck<EOL>def kclear():
libspice.kclear_c()<EOL>
Clear the KEEPER subsystem: unload all kernels, clear the kernel
pool, and re-initialize the subsystem. Existing watches on kernel
variables are retained.

http://naif.jpl.nasa.gov/pub/naif/toolkit_docs/C/cspice/kclear_c.html