Ashya King was taken out of Southampton General Hospital by his mother and father against medical advice.
Hampshire Police believe he may have been taken to Spain and police are at a Marbella property owned by the family.
Officers said they now thought his family had "taken steps to be able to feed him".
It was unclear precisely what they meant but Hampshire Assistant Chief Constable Chris Shead added: "The feeding system that Ashya needs and the other associated medical care is complex, and I would appeal to Ashya's family not to think that they are able to administer this care themselves."
It is feared the battery on his medical feeding unit, which is designed only for temporary use and is not easy to replace, has now run out.
He said it was unclear whether Ashya's parents had spare batteries.
"Without properly administered food Ashya's situation is very serious," he said.
Ashya and his family were last seen on a ferry to France on Thursday evening.
Mr Shead cautioned it was possible the family may not have travelled on to Spain and asked people across Europe to remain vigilant.
According to Ian Pople, a consultant neurosurgeon, the battery in the feeding machine used by Ashya can't be changed easily.
It is integrated within the machine, much like an iPhone, and it means the machine has to be taken apart to replace the battery.
It's also not designed to be run on batteries for a long period and is usually plugged into the mains.
In other words, it's only battery-reliant for short periods, such as going to the toilet, or moving between wards.
Although the arrest warrant was "based around neglect", Mr Shead said this did not necessarily mean the parents would be charged with that offence.
"It purely gives us the power to arrest and then we will be able to speak to them," he said.
Ashya's paternal grandmother, Patricia King, said the couple were "wonderful" and had been distraught at their child's illness.
Ms King, who lives in Southsea, said her son was "the most caring and wonderful father you could ever have".
She also praised her daughter-in-law, saying she had kept a bedside vigil while Ashya was in hospital.
"We are a very close family," she said.
Mr Shead said his force was considering sending officers from Hampshire to assist Spanish police in Marbella.
He also thanked the Spanish authorities for their help with the search for the family and urged any medical professionals to be on the lookout for the family.
Mr Shead said the latest information was "positive", adding: "There have been widespread media alerts across Europe.
"We would now encourage anyone with links to Spain particularly, to also help us spread the appeal via social media."
Interpol has issued a missing persons alert to all 190 of its member countries and said it was treating all information on the case as "high priority".
Brett King, 51, and Naghemeh King, 45, removed Ashya from the ward on Thursday.
A spokesman for the hospital, which contacted police six hours after the family left, said on Friday: "Ashya was a long-term patient who was permitted to leave the ward under the supervision of his parents as part of his ongoing rehabilitation.
"When the length of time he had been absent became a cause of concern to staff yesterday afternoon they contacted police after a search of the site and attempts to contact the family were unsuccessful."
Mr Shead said police were told by the hospital the child was missing at 20:35 BST on Thursday - more than six hours after he had been taken by his parents.
On why the hospital did not alert police sooner, he said: "That is something that we need to look at."
Parents have the right to remove their children from hospital unless they are prevented from doing so by a court order - it has not been confirmed whether Ashya was subject to an order.
If doctors are concerned that parents intend to remove a child, deny it the medical treatment it needs, and expose it to the risk of serious harm, they can seek a court order.
This will normally involve CAFCASS (the Children and Family Court Advisory and Support Service), the non-departmental public body which provides guardians to represent the best interests of children in family court proceedings.
Once an order is in place, any parent who removes their child in breach of the order is committing a contempt of court for which they could be imprisoned.
Hampshire Police confirmed the family are Jehovah's Witnesses, but there is no suggestion this is why he was taken.
Officers were keeping an "open mind" on the motives, Mr Shead said.
The Office of Public Information for Jehovah's Witnesses said in a statement: "There is absolutely no indication, as far as we are aware, that their decision is in any way motivated by any religious convictions."
Jehovah's Witnesses say they refuse blood transfusions on the basis of biblical teaching. Their website says the Old and New Testaments "clearly command us to abstain from blood".
The family, from Southsea, Hampshire, were travelling in a grey Hyundai I800 Style CRDI, registration KP60 HWK. Officers have asked for anyone who sees the vehicle to contact them.

A European arrest warrant has been issued for the parents of a five-year-old boy with a brain tumour, missing from hospital since Thursday.


The service said it had a shortage of 24 staff - the equivalent of 12 ambulance crews - that could have led to delays for "less serious calls".
It said support was sought from voluntary and private ambulance crews.
The shortage was due to a factors including rostered leave, sickness, vacant shifts and cancelled overtime.
John McPoland from the NIAS said the shortage left the service about 20% down on the usual 60 crews it expected to have in place for a Saturday night shift.
He added that the staff shortage was an ongoing issue.
"We are experiencing difficulty at the weekend and we have been relying on the voluntary crews and on the private ambulances," he said.
"We also rely on our staff coming in and doing overtime.
"We have been dealing with situations like this for quite a while now.
"We're absolutely not happy about it but we will take steps to try to address it."
He added that the reduced service would mostly be felt by patients "whose situation is not immediately or potentially life-threatening".

The Northern Ireland Ambulance Service (NIAS) has said it had to operate a reduced level of cover on Saturday night due to a shortage of staff.


Were rolling Suicide
Wake up
Grab a brush and put a little makeup
Hide your scars to fade away the shakeup
Whyd you leave the keys upon the table?
Here you go, create another fable, you wanted to
Grab a brush and put a little makeup, you wanted to
Hide the scars to fade away the shakeup, you wanted to
Whyd you leave the keys upon the table? You wanted to
I dont think you trust
In my self-righteous suicide
I cry when angels deserve to die
Ah! Wake up
Grab a brush and put a little makeup
Hide the scars to fade away the
Whyd you leave the keys upon the table?
Here you go, create another fable, you wanted to
Grab a brush and put a little makeup, you wanted to
Hide the scars to fade away the shakeup, you wanted to
Whyd you leave the keys upon the table? You wanted to
I dont think you trust
In my self-righteous suicide
I cry when angels deserve to die
In my self-righteous suicide
I cry when angels deserve to die
Father, father, father, father
Father, father, father, father
Father, into your hands I commend my spirit
Father, into your hands
Why have you forsaken me?
In your eyes, forsaken me?
In your thoughts, forsaken me?
In your heart, forsaken me? Oh
Trust in my self-righteous suicide
I cry when angels deserve to die
In my self-righteous suicide
I cry when angels deserve to die


Conversion, software version 7.0
Looking at life through the eyes of a tire hub
Eating seeds as a pastime activity
The toxicity of our city, of our city
You, what do you own the world? How do you own disorder, disorder?
Now, somewhere between the sacred silence, sacred silence and sleep
Somewhere between the sacred silence and sleep
Disorder, disorder, disorder
More wood for their fires, loud neighbors
Flashlight reveries caught in the headlights of a truck
Eating seeds as a pastime activity
The toxicity of our city, of our city
You, what do you own the world? How do you own disorder, disorder?
Now, somewhere between the sacred silence, sacred silence and sleep
Somewhere between the sacred silence and sleep
Disorder, disorder, disorder
You, what do you own the world? How do you own disorder?
Now, somewhere between the sacred silence, sacred silence and sleep
Somewhere between the sacred silence and sleep
Disorder, disorder, disorder
When I became the sun, I shone life into the mans hearts
When I became the sun, I shone life into the mans hearts


You!
Why do they always send the poor?
Barbarisms by Barbaras with pointed heels
Victorious victories kneel for brand new spanking deals
Marching forward, hypocritic and hypnotic computers
You depend on our protection, yet you feed us lies from the table cloth
La, la, la, la, la, la, la, la, la, la, ooh-ooh
Everybodys going to the party, have a real good time
Dancing in the desert, blowing up the sunshine
Kneeling roses disappearing into Moses dry mouth
Breaking into Fort Knox, stealing our intentions
Hangars sitting dripped in oil, crying, Freedom
Handed to obsoletion, still, you feed us lies from the table cloth
La, la, la, la, la, la, la, la, la, la, ooh-ooh
Everybodys going to the party, have a real good time
Dancing in the desert, blowing up the sunshine
Everybodys going to the party, have a real good time
Dancing in the desert, blowing up the sunshine
Blast off, its party time
And we dont live in a fascist nation
Blast off, its party time
And where the fuck are you?
Where the fuck are you?
Where the fuck are you?
Why dont presidents fight the war?
Why do they always send the poor?
Why dont presidents fight the war?
Why do they always send the poor?
Why do they always send the poor?
Why do they always send the poor?
Why they always send the poor?
Kneeling roses disappearing into Moses dry mouth
Breaking into Fort Knox, stealing our intentions
Hangars sitting dripped in oil, crying, Freedom
Handed to obsoletion, still, you feed us lies from the table cloth
La, la, la, la, la, la, la, la, la, la, ooh-ooh
Everybodys going to the party, have a real good time
Dancing in the desert, blowing up the sunshine
Everybodys going to the party, have a real good time
Dancing in the desert, blowing up the sun
Where the fuck are you?
Where the fuck are you?
Why dont presidents fight the war?
Why do they always send the poor?
Why dont presidents fight the war?
Why do they always send the poor?
Why do they always send the poor?
Why do they always send the poor?
Why do they always send the poor?
Why do they always send the poor?
Why do they always send the poor?
They always send the poor, they always send the poor


Life is a waterfall
Were one in the river and one again after the fall
Swimming through the void, we hear the word
We lose ourselves, but we find it all
Cause we are the ones that wanna play
Always wanna go, but you never wanna stay
And we are the ones that wanna choose
Always wanna play, but you never wanna lose
Aerials in the sky
When you lose small mind, you free your life
Life is a waterfall
We drink from the river then we turn around and put up our walls
Swimming through the void, we hear the word
We lose ourselves, but we find it all
Cause we are the ones that wanna play
Always wanna go, but you never wanna stay
And we are the ones that wanna choose
Always wanna play, but you never wanna lose, oh
Aerials in the sky
When you lose small mind, you free your life
Aerials, so up high
When you free your eyes, eternal prize
Aerials in the sky
When you lose small mind, you free your life
Aerials, so up high
When you free your eyes, eternal prize
Ah, ah, ah, ah, ah, ah
Ah, ah, ah-ah, ah-ah, ah-ah-ah
Ah, ah, ah, ah, ah, ah
Ah, ah, ah-ah, ah-ah, ah-ah, om


The Kombucha mushroom people, sitting around all day
Who can believe you? Who can believe you?
Let your mother pray
Sugar
Sugar
Im not there all the time, you know
Some people, some people, some people call it insane
Yeah, they call it insane
I play Russian Roulette every day, a mans sport
With the bullet called life
Yeah, mama called life
Yeah and every time I try to go where I really want to be
Its already where I am
Cause Im already there
The Kombucha mushroom people, sitting around all day
Who could believe you? Who could believe you?
Let your mother pray
Sugar
I got a gun the other day from Sako
Its cute, its small, fits right in my pocket
Yeah, right in my pocket
My girl, you know, she lashes out at me sometimes
And I just fucking kick her
And then, ooh baby, shes okay
People are always chasing me down
Tryna push my face to the ground
Where all they do is suck out my motherfucking brains
My brains
The Kombucha mushroom people, sitting around all day
Who can believe you? Who can believe you?
Let your mother pray
I sit in my desolate room
No lights, no music
Just anger, I killed everyone
Im away forever, but Im feeling better
How do I feel? What do I say?
Fuck you, it all goes away
How do I feel? What do I say?
Fuck you, it all goes away
How do I feel? What do I say?
In the end, it all goes away
How do I feel? What do I say?
In the end, it all goes away
How do I feel? What do I say?
In the end, it all goes away
How do I feel? What do I say?
In the end, it all goes away
How do I feel? What do I say?
In the end, it all goes away
How do I feel? What do I say?
In the end, it all goes away
In the end, it all goes away
In the end, it all goes away
In the end, it all goes away
In the end, it all goes away


Why dont you ask the kids at Tiananmen Square?
Was fashion the reason why they were there?
They disguise it, hypnotize it
Television made you buy it
Im just sitting in my car and waiting for my
Shes scared that I will take her away from there
Dreams and her country left with no one there
Mesmerized the simple-minded
Propaganda leaves us blinded
Im just sitting in my car and waiting for my girl
Im just sitting in my car and waiting for my girl
Im just sitting in my car and waiting for my girl
Im just sitting in my car and waiting for my girl


Such a lonely day and its mine
The most loneliest day of my life
Such a lonely day, should be banned
Its a day that I cant stand
The most loneliest day of my life
The most loneliest day of my life
Such a lonely day, shouldnt exist
Its a day that Ill never miss
Such a lonely day and its mine
The most loneliest day of my life
And if you go, I wanna go with you
And if you die, I wanna die with you
Take your hand and walk away
The most loneliest day of my life
The most loneliest day of my life
The most loneliest day of my life
Such a lonely day and its mine
Its a day that Im glad I survived


Theyre tryna build a prison
Theyre tryna build a prison
Oh
Following the rights movements, you clamped down with your iron fists
Drugs became conveniently available for all the kids
Following the rights movements, you clamped down with your iron fists
Drugs became conveniently available for all the kids
I buy my crack, my smack, my bitch
Right here in Hollywood
Nearly two million Americans are incarcerated
In the prison system, prison system of the US
Theyre tryna build a prison
Theyre tryna build a prison
Theyre tryna build a prison
Theyre tryna build a prison
For you and me to live in
Another prison system
Another prison system
Another prison system
For you and me
Minor drug offenders fill your prisons, you dont even flinch
All our taxes paying for your wars against the new non-rich
Minor drug offenders fill your prisons, you dont even flinch
All our taxes paying for your wars against the new non-rich
I buy my crack, my smack, my bitch
Right here in Hollywood
The percentage of Americans in the prison system
Prison system has doubled since 1985
Theyre tryna build a prison
Theyre tryna build a prison
Theyre tryna build a prison
Theyre tryna build a prison
For you and me to live in
Another prison system
Another prison system
Another prison system
For you and me
For you and I, you and I, you and I, you and I
Theyre tryna build a prison
Theyre tryna build a prison
Theyre tryna build a prison for you and me
Oh, baby, you and me
Oh, oh
All research and successful drug policy
Shows that treatment should be increased
Oh
And law enforcement decreased
While abolishing mandatory minimum sentences
Oh
All research and successful drug policy
Shows that treatment should be increased
Oh
And law enforcement decreased
While abolishing mandatory minimum sentences
Utilizing drugs to pay for secret wars around the world
Drugs are now your global policy, now you police the globe
I buy my crack, my smack, my bitch
Right here in Hollywood
Drug money is used to rig elections and train brutal
Corporate sponsored dictators around the world
Theyre tryna build a prison
Theyre tryna build a prison
Theyre tryna build a prison
Theyre tryna build a prison
For you and me to live in
Another prison system
Another prison system
Another prison system
For you and me
For you and I, you and I, you and I, you and me
Theyre tryna build a prison
Theyre tryna build a prison
Theyre tryna build a prison for you and me
Oh, baby, you and me


Dead man lying on the bottom of the grave
Wondering when savior comes, is he gonna be saved?
Maybe youre a sinner into your alternate life
Maybe youre a joker, maybe you deserve to die
They were crying when their sons left, God is wearing black
Hes gone so far to find no hope, hes never coming back
They were crying when their sons left, all young men must go
Hes come so far to find the truth, hes never going home
Young men standing on the top of their own graves
Wondering when Jesus comes, are they gonna be saved?
Cruelty to the winner, bishop tells the king his lies
Maybe youre a mourner, maybe you deserve to die
They were crying when their sons left, God is wearing black
Hes gone so far to find no hope, hes never coming back
They were crying when their sons left, all young men must go
Hes come so far to find the truth, hes never going home
Welcome to the soldier side, where theres no one here but me
People all grow up to die, there is no one here but me
Welcome to the soldier side, there is no one here but me
People on the soldier side, there is no one here but me


Na-na-na, na-na-na-na, na-na-na-na-na
Hey you, see me, pictures, crazy
All the world Ive seen before me passing by
Ive got nothing; to gain, to lose
All the world Ive seen before me passing by
You dont care bout how I feel
I dont feel there anymore
You dont care bout how I feel
I dont feel there anymore
You dont care bout how I feel
I dont feel there anymore
You dont care bout how I feel
I dont feel it anymore
Anymore, na-na-na, na-na-na-na, na-na-na-na
Hey, you are me, not so pretty
All the world Ive seen before me passing by
Silent, my voice, Ive got no choice
All the world Ive seen before me passing by
You dont care bout how I feel
I dont feel there anymore
You dont care bout how I feel
I dont feel there anymore
You dont care bout how I feel
I dont feel there anymore
You dont care bout how I feel
I dont feel it anymore
I dont see
I dont hear
I dont speak
I dont feel...
Na-na-na, na-na-na-na, na-na-na-na-na
Na-na-na, na-na-na-na, na-na-na-na-na
Hey you, see me, pictures, crazy
All the world Ive seen before me passing by
Ive got nothing; to gain, to lose
All the world Ive seen before me passing by
You dont care bout how I feel
I dont feel there anymore
You dont care bout how I feel
I dont feel there anymore
You dont care bout how I feel
I dont feel there anymore
You dont care bout how I feel
I dont feel it anymore
I dont sleep
I dont eat
I dont live
I dont feel


sooner

preferably sooner sooners okie Oklahoman


demand

necessitate demands request requirement activity imposition need demand


the clinical features of our cases demonstrated some of the already known characteristics of the variable spectrum of hiv infection da are the most important risk category in italy of the arc cases evolved into aids during a month followup on average the most frequent oi in our aids cases were pcp c albicans esophagitis and chronic mucocutaneous ulcers an high percentage of neurologic involvement from hiv was observed and HM were encountered in aids ks and undifferentiated b lymphoma as well as in arc HD statistically significant worsening of the immunologic situation is evident as the disease progresses from las to aids G1 b lymphocytes represent most of the cells of the germinal center during the hyperplastic stage of lymphadenopathy reversal of the tt ratio appears early during the initial stage of lymphadenopathy and is due to a decrease of cd and a relative increase of cd also destruction of the follicular dendritic cells is an early feature which becomes more evident as the disease advances and the lymph node evolves toward progressive involution activated blymphocyte augmentation with polyclonal ig secretion appears to be related to TI b stimulation by coinfection such as cmv ebv and hbv the increase of CD8 lymphocytes seems to be partly related to the excessive activation of b lymphocytes and partially directed to the cells INF by hiv or coated with its proteins the destruction of follicular dendritic cells has been interpreted not only as a killer effect of the virus but also as a result of the intervention of ctl sensitized to the cells containing the virus their destruction may contribute to the impaired recognition of soluble antigen which is one of the main features of the immune deficiency of hiv infection


ceftobiprole bpr is an investigational cephalosporin with activity against staphylococcus aureus including methicillinresistant s aureus mrsa strains the pharmacodynamic pd profile of bpr against s aureus strains with a variety of susceptibility phenotypes in an immunocompromised murine pneumonia model was characterized the bpr mics of the test isolates ranged from to mugml pharmacokinetic pk studies were conducted with infected neutropenic balbc mice and the bpr concentrations were measured in plasma epithelial lining fluid elf and lung tissue pd studies with these mice were undertaken with eight s aureus isolates two MSSA strains three hospitalacquired mrsa strains and three CA mrsa strains subcutaneous bpr doses of to mgkg of body weightday were administered and the NC in the number of log cfuml in lungs was evaluated after h of therapy the pd profile was characterized by using the free drug exposures f determined from the following parameters the percentage of time that the concentration was greater than the mic t mic the Cmax in serummic and the area under the concentrationtime curvemic the bpr pk parameters were linear over the dose range studied in plasma and the elf concentrations ranged from to of the free plasma concentration ft mic was the parameter that best correlated with tau against a diverse array of s aureus isolates in this mu pneumonia model the effective dose ed ed and stasis exposures appeared to be similar among the isolates studied bpr exerted maximal antibacterial effects when ft mic ranged from to regardless of the phenotypic profile of resistance to betalactam fluoroquinolone erythromycin clindamycin or TCs


we have taken a basic biologic RPA to elucidate the pathophysiology of BPD bpd the CLD based on cellmolecular mechanisms of physiologic lung OD stretch coordinates PTHrP pthrp signaling between the ATII cell and the mesoderm to coordinately upregulate key genes for the homeostatic FB phenotype including peroxisome proliferator G1 TRG ppargamma adipocyte differentiation related protein adrp and OB and the retrograde stimulation of type ii cell surfactant synthesis by leptin each of these paracrine interactions requires cellspecific receptors on adjacent cells derived from the mesoderm or endoderm respectively to serially upregulate the signaling pathways between and within each celltype it is this PET compartmentation that is key to understanding how specific agonists and antagonists can predictably affect this mechanism of AM homeostasis using a wide variety of pathophysiologic insults associated with bpd barotrauma oxotrauma and infection we have found that there are type ii cell andor FB cellmolecular effects generated by these insults which can lead to the bpd phenotype we have exploited these cellspecific mechanisms to effectively prevent and treat lung injuries using ppargamma agonists to sustain this signaling pathway it is critically important to judiciously select physiologically and developmentally relevant interventions when treating the preterm neonate


lipoperoxidationderived aldehydes for example MDA mda can damage proteins by generating covalent adducts whose accumulation probably participates in tissue damage during aging however the mechanisms of adduct formation and their stability are scarcely known this article investigates whether oxidative steps are involved in the process as a MM of the process the interaction between mda and bovine SS Al bsa was analyzed incubation of bsa with mda resulted in rapid quenching of tryptophan fluorescence and appearance of mda protein adduct fluorescence transition metal ion traces interfered with the latter process mda induced generation of peroxides in bsa which was preventable with the antioxidant BHT bht mdaexposed bsa underwent aggregation degradation and bhtsensitive gel retardation effects phycoerythrin fluorescence disappearance a marker of damage mediated by ROS species indicated synergism between mda and metal ions the interaction between reactive aldehydes and proteins is likely to occur in several steps some of them oxidative in nature giving rise to T3 LPO endproducts which could participate with AGEs in the generation of tissue damage during aging


gb virus c gbvc or HGV hgv is transmitted by the parenteral route but the importance of sexual transmission needs to be ascertained gbvchgv infections were investigated using rna and eantibody PCD methods in subjects INF by the HIV-1 hiv divided into groups of individuals each according to their main risk factor for hiv infection blood product recipients group intravenous drug users group homosexuals group or heterosexual SE group the overall prevalence of gbvchgv infection was no significant difference was observed in gbvc hgv prevalence among the four CG and in CG and respectively hepatitis c virus hcv antibodies used as a control for parenteral exposure were found in and of the subjects in groups and versus only and of the subjects in groups and respectively p similarly coinfections with gbvchgv and hcv were significantly associated with the parenteral route p these data emphasized the usefulness of combining the detection of rna and the e antibody to determine the actual prevalence of gbvchgv infection the high prevalence of the gbvchgv markers among the HIV+ subjects especially those with sexual exposure provides additional evidence that this route of transmission plays a key role in the epidemiology of gbvchgv the potential influence of gbvchgv infection on the course of hiv disease needs further DUE


to quantify the amount of CL NO harvested in modified RND


backward SBS was used to control the growth of ASE ase reducing the unwanted emission in a pulseamplified cw tisapphire laser system from to less than x in the final output suppression of ase substantially improved the spectral SQ of the laser and broadened the range over which the laser is useful the SO duration was compressed but the pulse remained nearly transform limited


in order to study the rate of intestinal absorption and hepatic uptake of mediumchain fatty acids mcfa six growing pigs mean body weight kg were fitted with a permanent fistula in the duodenum and with three catheters in the portal vein i.c. and HV respectively two electromagnetic flow probes were also set up one around the portal vein and one around the hepatic artery a mixture of octanoic and decanoic acids esterified as mediumchain triacylglycerols together with maltose dextrine and a nitrogenous fraction was continuously infused for h into the duodenum samples of blood were withdrawn from the three vessels at regular intervals for h and further analysed for their nonesterified octanoic and decanoic acid contents the concentration of nonesterified octanoic and decanoic acids in the portal blood rose sharply after the beginning of each infusion and showed a biphasic timecourse with two maximum values one T3 min and a later one between and min only of octanoic acid infused into the duodenum and of C10 were recovered in the portal flow throughout each experiment the amounts of nonesterified mcfa taken up per h by the liver were close to those absorbed from the gut via the portal vein within the same periods of time showing that the liver is the main site of utilization of mcfa in pigs these results have been discussed with a special emphasis laid on the possible mechanisms of the biphasic timecourse of mcfa absorption and the incomplete REC in the HPB of the infused fatty acids


based on traditional chinese medicine theory and clinical experience traditional chinese herbal drug toxicity has its own special connotation from the perspective of history and logic the different comprehension of toxicity between western medicine and traditional chinese medicine was discussed after retracing the meaning of drug toxicity in traditional chinese medicine the authors suggest that its not feasible to T0 the chinese medicine coping mechanically and applying indiscriminately the concept and the research idea about modern drug toxicity since there is different understanding of drug toxicity between traditional chinese medicine and WM many control elements are involved in the use of traditional chinese herbal drugs and chinese drug components and actions are complex as compared with western drugs more and more drugs with toxicity will be found due to the relativity of drug toxicity currently the study of chinese drug toxicity should pay more attention to the relation between the toxicity and chinese drug nature compatibility and the corresponding disease or syndrome DP T3 making definition of chinese drug toxicity and its connotation


A Porthcawl RNLI crew with a medic and the coastguard search and rescue helicopter were sent to Sker Beach, near Kenfig Nature Reserve, at 12:50 GMT on Sunday.
Crewman Chris Page said the rider had head injuries and was very cold from lying unconscious on wet sand.
She was treated before being flown to Cardiff's University Hospital of Wales.

A woman has been airlifted to hospital after falling from a horse on a Bridgend county beach.


Verheydt, who had been with Maastricht since 2015, has signed a three-year contract with Harry Kewell's side.
The 25-year-old scored 13 goals in 43 appearances in all competitions last season.
Meanwhile, Watford winger Dennon Lewis, 20, has joined the Reds on a loan deal until 31 December.
Lewis, who made 29 National League appearances on loan at Woking last season, played under Kewell when the Australian was coach of Watford's under-23 team.
Find all the latest football transfers on our dedicated page.

League Two side Crawley Town have signed striker Thomas Verheydt from Dutch second-tier side MVV Maastricht for an undisclosed fee.


The 32-year-old had been playing in the Isthmian Premier Division with Leatherhead following his release by Newport at the end of last season.
Pidgeley has made 260 appearances in spells with nine clubs, including Chelsea, Watford and Millwall.
Forest Green are currently second in the National League table, one point behind leaders Cheltenham Town.
Pidgeley could make his Rovers debut when they host Aldershot on Friday.

National League side Forest Green Rovers have signed goalkeeper Lenny Pidgeley until the end of the season.


The suspected green mamba was found on a ship that had docked in Aberdeen from west Africa last month.
The snake died after it was placed in a freezer by the animal charity after attempts to rehome it with specialist reptile keepers failed.
The snake was later identified as a harmless green tree snake.
Police Scotland said a complaint was under consideration.
Scottish SPCA Ch Supt Mike Flynn said: "We were called out after a green snake arrived in Aberdeen on a boat from Africa.
"The snake was thought to be a green mamba, one of the deadliest snakes in the world. The snake was taken by police escort to our Aberdeenshire animal rescue and rehoming centre.
"Sadly the snake, which staff genuinely believed to be a green mamba, had to be put to sleep after our attempts to rehome it to specialist reptile keepers were unsuccessful."
He added: "We could not keep the snake in our centre due to severe health and safety concerns, as the closest anti-venom is held in Bedford. Green mambas also require a Dangerous Wild Animal Licence which the society does not have.
"The safety of our staff and the public is paramount and as such the snake was placed in a freezer where it passed away.
"The Scottish SPCA is proud of its policy not put healthy animals to sleep. Animals are only put to sleep on veterinary advice if they are too ill or too aggressive to be rehomed, or where we are legally required to do so.
"The decision to euthanise the snake was not taken lightly. Unfortunately, the snake has since been identified as a harmless green tree snake. This has been an honest mistake on the society's part as we genuinely believed this was an extremely deadly snake."
The western green mamba feeds on small animals and rodents and is mainly found in the coastal tropical rainforests of western Africa.
Experts say its bite can be fatal in as little as 30 minutes.

A complaint about the Scottish SPCA putting what was thought to be one of the world's most deadly snakes to sleep is being investigated by police.


The all-rounder has been included in the T20 squad to face Sri Lanka on 5 July at the Ageas Bowl, having been part of the World T20 squad in March.
"It's nice to be involved again," the 26-year-old slow left-armer and right-handed batsman told BBC Radio Solent.
"I wasn't expecting to be as I thought Moeen Ali would, but him being rested hands me another opportunity."
Dawson failed to make an appearance during England's run to the World T20 final in India this year, but his limited-overs performances for Hampshire this season have kept him in contention.
"I'm not sure what team they'll go with," he said.
"I've had some good performances for Hampshire in one-day and T20 cricket and if I keep going with that, hopefully I might get a chance."

Hampshire's Liam Dawson says it would be "amazing" to make his England Twenty20 debut on his home ground.


The Egypt-backed plan had envisaged a regional forum which analysts say might have forced Israel to reveal whether or not it has nuclear weapons.
The proposal was blocked by the US, the UK and Canada. The next review is set for  2020.
Israel neither confirms nor denies it has a stockpile of nuclear weapons.
Speaking after four weeks of negotiations, US Under-Secretary of State Rose Gottemoeller accused Egypt and other Arab countries of "not willing to let go of these unrealistic and unworkable conditions" for future talks.
She also said some participants tried to "cynically manipulate" the whole process.
But Egypt warned that the failure to reach a deal "will have consequences in front of the Arab world and public opinion", the Associated Press news agency reports.
Last month, Egypt had proposed to stage a regional conference - with or without Israel's participation and without an agreed agenda.
Some analysts suggested that this move might have forced Israel - which is not a party to the Treaty on the Non-Proliferation of Nuclear Weapons (NPT) - to publicly clarify its position on nuclear weapons.
Decisions at NPT review conferences - held every five years - are made by consensus.
The failure of the current talks means the next gathering could only be held in 2020 at the earliest.

A UN conference aimed at preventing the proliferation of nuclear weapons has ended in failure after a row over a nuclear-free Middle East proposal.


Mothers-to-be are more likely to get malaria as their immunity is lowered, says the Royal College of Obstetricians and Gynaecologists (RCOG).
Malaria carries serious risks for mother and baby including miscarriage, stillbirth and premature labour.
The tropical disease is transmitted by mosquitoes and causes a fever, flu-like symptoms, vomiting and diarrhoea.
There have been no malaria-related deaths in pregnant or recently pregnant women in the UK in the past decade but the RCOG says it has been receiving inquires from worried women.
In the UK, about 1,500 cases of malaria are reported each year and about 10 people will die, said the RCOG.
It says all non-essential trips to areas with a high risk of malaria should be avoided.
Risk areas include large areas of Africa, Asia including China and India, Central and South America, parts of the Middle East and some Pacific Islands.
If the trip is unavoidable, the college advises women to seek advice from a centre with expertise in malaria which will provide information on ways to reduce the risk of infection.
Women should make sure they are aware of the risk, take out measures such as mosquito nets for bite prevention and take anti-malarial medication.
Philippa Marsden, who chairs the RCOG's patient information committee, said although the risks were still relatively small it was important that women were well-informed.
Cath Broderick of the RCOG women's network said: "If women are worried about symptoms after returning from a high-risk country and think they may have malaria, they should see a doctor immediately and inform them of their recent travels."
Symptoms can take a week or more to develop after being bitten.

Pregnant women should visit countries with a risk of malaria only if their trip is essential, experts are warning.


Researchers at the University of Sheffield said the tumours were effectively "fertilising" the bone to help themselves grow.
The study, in the journal Nature, said it may be possible to protect bone from a tumour's nefarious influence and consequently stop the cancer's spread.
Cancer charities said this opened up "a whole new avenue for research".
Around 85% of breast cancers that spread around the body end up in bone, at which point the cancer is difficult to treat and more deadly.
The scientists, in Sheffield and the University of Copenhagen, discovered patients with secondary cancers had higher levels of an enzyme called LOX being produced by their tumours and released into the blood.
Bone is constantly being broken down and rebuilt. But in a series of experiments on mice, the research team showed LOX was disrupting the process and leaving lesions and holes in the bone.
Using drugs to block LOX prevented the cancer from spreading.
Dr Alison Gartland, a reader in bone and cancer biology at the university, told the BBC News website: "We think it's a significant breakthrough in trying to prevent metastases (secondary tumours) in breast cancer.
"The cancer cells in the primary tumour are actually fertilising the soil for the future growth of itself, LOX is changing the environment in bone to make it better to grow."
The animal tests also showed that a set of osteoporosis drugs called bisphosphonates could prevent the spread of cancer.
Bisphosphonates also interfere with the way bone is recycled in order to strengthen it.
They are already given to some cancer patients, but the Sheffield team believe they could have a much larger role.
The effect was discovered only in oestrogen-negative breast cancers. They account for around a third of cases, but are far more deadly.
Katherine Woods, from Breast Cancer Campaign and Breakthrough Breast Cancer, said: "By unveiling the role that the protein LOX is playing, these results open up a whole new avenue for research and treatments that could stop breast cancer spreading to the bone.
"The research also adds weight to the growing body of evidence supporting the role of bisphosphonates in stopping secondary breast cancer in its tracks.
"The reality of living with secondary breast cancer in the bone is a stark one, which leaves many women with bone pain and fractures that need extensive surgery just when they need to be making the most of the time they have left with friends and family."
The findings may also apply in colon cancer.

Breast cancers can manipulate the structure of bone to make it easier to spread there, a study has found.


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Context: This is the most common method of construction procurement and is well established and recognized. In this arrangement, the architect or engineer acts as the project coordinator. His or her role is to design the works, prepare the specifications and produce construction drawings, administer the contract, tender the works, and manage the works from inception to completion. There are direct contractual links between the architect's client and the main contractor. Any subcontractor has a direct contractual relationship with the main contractor. The procedure continues until the building is ready to occupy.

Question: There are direct contractual links between who?


Context: After strengthening his government in northern China, Kublai pursued an expansionist policy in line with the tradition of Mongol and Chinese imperialism. He renewed a massive drive against the Song dynasty to the south. Kublai besieged Xiangyang between 1268 and 1273, the last obstacle in his way to capture the rich Yangzi River basin. An unsuccessful naval expedition was undertaken against Japan in 1274. Kublai captured the Song capital of Hangzhou in 1276, the wealthiest city of China. Song loyalists escaped from the capital and enthroned a young child as Emperor Bing of Song. The Mongols defeated the loyalists at the battle of Yamen in 1279. The last Song emperor drowned, bringing an end to the Song dynasty. The conquest of the Song reunited northern and southern China for the first time in three hundred years.

Question: What area was Kublai trying to capture by defending Xiangyang?


Context: The neighborhood of Sunnyside is on Fresno's far southeast side, bounded by Chestnut Avenue to the West. Its major thoroughfares are Kings Canyon Avenue and Clovis Avenue. Although parts of Sunnyside are within the City of Fresno, much of the neighborhood is a "county island" within Fresno County. Largely developed in the 1950s through the 1970s, it has recently experienced a surge in new home construction. It is also the home of the Sunnyside Country Club, which maintains a golf course designed by William P. Bell.

Question: Where is the home of the Sunnyside Country Club?


Context: The historical measure of a steam engine's energy efficiency was its "duty". The concept of duty was first introduced by Watt in order to illustrate how much more efficient his engines were over the earlier Newcomen designs. Duty is the number of foot-pounds of work delivered by burning one bushel (94 pounds) of coal. The best examples of Newcomen designs had a duty of about 7 million, but most were closer to 5 million. Watt's original low-pressure designs were able to deliver duty as high as 25 million, but averaged about 17. This was a three-fold improvement over the average Newcomen design. Early Watt engines equipped with high-pressure steam improved this to 65 million.

Question: What was the ideal duty of a concept engine?


Context: Imperialism and colonialism both dictate the political and economic advantage over a land and the indigenous populations they control, yet scholars sometimes find it difficult to illustrate the difference between the two. Although imperialism and colonialism focus on the suppression of an other, if colonialism refers to the process of a country taking physical control of another, imperialism refers to the political and monetary dominance, either formally or informally. Colonialism is seen to be the architect deciding how to start dominating areas and then imperialism can be seen as creating the idea behind conquest cooperating with colonialism. Colonialism is when the imperial nation begins a conquest over an area and then eventually is able to rule over the areas the previous nation had controlled. Colonialism's core meaning is the exploitation of the valuable assets and supplies of the nation that was conquered and the conquering nation then gaining the benefits from the spoils of the war. The meaning of imperialism is to create an empire, by conquering the other state's lands and therefore increasing its own dominance. Colonialism is the builder and preserver of the colonial possessions in an area by a population coming from a foreign region. Colonialism can completely change the existing social structure, physical structure and economics of an area; it is not unusual that the characteristics of the conquering peoples are inherited by the conquered indigenous populations.

Question: what do conquering people take away from native populations?


Context: Bills can be introduced to Parliament in a number of ways; the Scottish Government can introduce new laws or amendments to existing laws as a bill; a committee of the Parliament can present a bill in one of the areas under its remit; a member of the Scottish Parliament can introduce a bill as a private member; or a private bill can be submitted to Parliament by an outside proposer. Most draft laws are government bills introduced by ministers in the governing party. Bills pass through Parliament in a number of stages:

Question: Who may also submit private bills to Parliament?

an outside proposer
an outside proposer
an outside proposer


import java . io . * ; import java . util . * ; import static java . lang . System . in ; class Main { static long mod = 1000000000 + 7 ; public static void main ( String [ ] args ) throws IOException { Scanner sc = new Scanner ( System . in ) ; int n = sc . nextInt ( ) ; int [ ] a = new int [ n ] ; for ( int i = 0 ; i < n ; i ++ ) a [ i ] = sc . nextInt ( ) ; long ans = help ( a ) ; System . out . println ( ans ) ; } static long help ( int [ ] a ) { if ( a [ 0 ] != 0 ) return 0 ; int maxDist = 0 ; for ( int w : a ) maxDist = Math . max ( maxDist , w ) ; int [ ] rec = new int [ maxDist + 1 ] ; for ( int w : a ) rec [ w ] ++ ; if ( rec [ 0 ] != 1 ) return 0 ; for ( int i = 1 ; i <= maxDist ; i ++ ) { if ( rec [ i ] < 1 ) return 0 ; } long [ ] dp = new long [ maxDist + 1 ] ; dp [ 0 ] = 1 ; for ( int i = 1 ; i <= maxDist ; i ++ ) { long base = power ( 2 , rec [ i - 1 ] ) - 1 ; dp [ i ] = power ( base , rec [ i ] ) * dp [ i - 1 ] % mod ; long sameLayer = ( ( long ) rec [ i ] ) * ( ( long ) rec [ i ] - 1 ) / 2 ; dp [ i ] = dp [ i ] * power ( 2 , sameLayer ) % mod ; } return dp [ maxDist ] ; } static long power ( long base , long p ) { long ans = 1 ; while ( p > 0 ) { if ( p % 2 == 1 ) ans = ans * base % mod ; base = base * base % mod ; p /= 2 ; } return ans ; } }

def powmod ( a , b , P ) : NEW_LINE INDENT if b == 0 : NEW_LINE INDENT return 1 NEW_LINE DEDENT stk = [ ] NEW_LINE while b > 1 : NEW_LINE INDENT stk . append ( b % 2 ) NEW_LINE b //= 2 NEW_LINE DEDENT c = a % P NEW_LINE while len ( stk ) > 0 : NEW_LINE INDENT t = stk . pop ( ) NEW_LINE c = ( c * c ) % P NEW_LINE if t == 1 : NEW_LINE INDENT c = ( c * a ) % P NEW_LINE DEDENT DEDENT return c NEW_LINE DEDENT N = int ( input ( ) ) NEW_LINE A = list ( map ( int , input ( ) . split ( ) ) ) NEW_LINE P = 10 ** 9 + 7 NEW_LINE def count ( A ) : NEW_LINE INDENT S = [ 0 for _ in range ( max ( A ) + 1 ) ] NEW_LINE for a in A : NEW_LINE INDENT S [ a ] += 1 NEW_LINE DEDENT if A [ 0 ] != 0 or S [ 0 ] != 1 : NEW_LINE INDENT return 0 NEW_LINE DEDENT cnt = 1 NEW_LINE for i in range ( 1 , len ( S ) ) : NEW_LINE INDENT if S [ i ] == 0 : return 0 NEW_LINE path1 = powmod ( ( powmod ( 2 , S [ i - 1 ] , P ) - 1 ) % P , S [ i ] , P ) NEW_LINE path2 = powmod ( 2 , S [ i ] * ( S [ i ] - 1 ) // 2 , P ) % P NEW_LINE cnt = cnt * path1 * path2 % P NEW_LINE DEDENT return cnt NEW_LINE DEDENT print ( count ( A ) ) NEW_LINE


from collections import defaultdict NEW_LINE def mod_pow ( x , n , mod ) : NEW_LINE INDENT if n == 0 : NEW_LINE INDENT return 1 NEW_LINE DEDENT res = mod_pow ( x * x % mod , n // 2 , mod ) NEW_LINE if n & 1 : NEW_LINE INDENT res = res * x % mod NEW_LINE DEDENT return res NEW_LINE DEDENT MOD = 10 ** 9 + 7 NEW_LINE N = int ( input ( ) ) NEW_LINE A = list ( map ( int , input ( ) . split ( ) ) ) NEW_LINE ok = True NEW_LINE zeros = 0 NEW_LINE cnt = defaultdict ( int ) NEW_LINE for i in range ( N ) : NEW_LINE INDENT if i == 0 : NEW_LINE INDENT if A [ i ] != 0 : NEW_LINE INDENT ok = False NEW_LINE DEDENT DEDENT if A [ i ] == 0 : NEW_LINE INDENT zeros += 1 NEW_LINE DEDENT cnt [ A [ i ] ] += 1 NEW_LINE DEDENT maxn = max ( cnt . keys ( ) ) NEW_LINE if zeros != 1 : NEW_LINE INDENT ok = False NEW_LINE DEDENT res = 1 NEW_LINE if ok == True : NEW_LINE INDENT for i in range ( 0 , maxn + 1 ) : NEW_LINE INDENT if i != 0 and cnt [ i ] == 0 : NEW_LINE INDENT ok = False ; NEW_LINE break NEW_LINE DEDENT K = cnt [ i ] NEW_LINE res = ( res * mod_pow ( 2 , K * ( K - 1 ) // 2 , MOD ) ) % MOD NEW_LINE if i != 0 : NEW_LINE INDENT t = cnt [ i - 1 ] NEW_LINE curr = mod_pow ( 2 , t , MOD ) NEW_LINE s = cnt [ i ] NEW_LINE curr2 = mod_pow ( curr - 1 + MOD , s , MOD ) NEW_LINE res = ( res * curr2 ) % MOD NEW_LINE DEDENT DEDENT DEDENT print ( res if ok == True else 0 ) NEW_LINE


import collections NEW_LINE MAX_N = 10 ** 5 + 1 NEW_LINE MOD = 1000000007 NEW_LINE same_dist = [ 0 ] * ( MAX_N + 1 ) NEW_LINE same_dist [ 1 ] = 1 NEW_LINE for i in range ( 2 , MAX_N + 1 ) : NEW_LINE INDENT same_dist [ i ] = same_dist [ i - 1 ] * pow ( 2 , i - 1 , MOD ) NEW_LINE same_dist [ i ] %= MOD NEW_LINE DEDENT n = int ( input ( ) ) NEW_LINE a = list ( map ( int , input ( ) . split ( ) ) ) NEW_LINE cnt_num = collections . Counter ( a ) NEW_LINE if not ( cnt_num [ 0 ] == 1 and a [ 0 ] == 0 ) : NEW_LINE INDENT print ( 0 ) NEW_LINE exit ( ) NEW_LINE DEDENT if len ( a ) == 1 : NEW_LINE INDENT print ( 1 ) NEW_LINE exit ( ) NEW_LINE DEDENT ans = 1 NEW_LINE cnt = 1 NEW_LINE for i in range ( 1 , n ) : NEW_LINE INDENT if cnt_num [ i ] == 0 : NEW_LINE INDENT print ( 0 ) NEW_LINE exit ( ) NEW_LINE DEDENT else : NEW_LINE INDENT ans *= same_dist [ cnt_num [ i ] ] NEW_LINE ans %= MOD NEW_LINE ans *= pow ( ( 2 ** cnt_num [ i - 1 ] - 1 ) , cnt_num [ i ] , MOD ) NEW_LINE ans %= MOD NEW_LINE DEDENT cnt += cnt_num [ i ] NEW_LINE if cnt == len ( a ) : NEW_LINE INDENT print ( ans ) NEW_LINE exit ( ) NEW_LINE DEDENT DEDENT


from collections import Counter NEW_LINE n = int ( input ( ) ) NEW_LINE a = [ int ( i ) for i in input ( ) . split ( ) ] NEW_LINE def power ( n , k ) : NEW_LINE INDENT if k == 0 : return 1 NEW_LINE elif k == 1 : return n NEW_LINE elif k % 2 == 0 : return power ( ( n ** 2 ) % mod , k // 2 ) NEW_LINE else : return ( n * power ( n , k - 1 ) ) % mod NEW_LINE DEDENT if a [ 0 ] != 0 or a . count ( 0 ) != 1 : print ( 0 ) NEW_LINE else : NEW_LINE INDENT c , ans , num , mod = Counter ( a ) , 1 , 1 , 10 ** 9 + 7 NEW_LINE for i in range ( 1 , max ( a ) + 1 ) : NEW_LINE INDENT if c [ i ] == 0 : NEW_LINE INDENT ans = 0 NEW_LINE break NEW_LINE DEDENT else : NEW_LINE INDENT ans = ( ans * power ( ( power ( 2 , num ) - 1 ) , c [ i ] ) * power ( 2 , c [ i ] * ( c [ i ] - 1 ) // 2 ) ) % mod NEW_LINE num = c [ i ] NEW_LINE DEDENT DEDENT print ( ans ) NEW_LINE DEDENT


import java . util . * ; public class Main { static final int MOD = 1_000_000_007 ; public static void main ( String [ ] args ) { Scanner sc = new Scanner ( System . in ) ; int n = sc . nextInt ( ) ; int [ ] a = new int [ n ] ; int [ ] d = new int [ n ] ; int dmax = 0 ; for ( int i = 0 ; i < n ; i ++ ) { a [ i ] = sc . nextInt ( ) ; d [ a [ i ] ] ++ ; dmax = Math . max ( a [ i ] , dmax ) ; } if ( a [ 0 ] != 0 || d [ 0 ] != 1 ) { System . out . println ( 0 ) ; return ; } for ( int i = 0 ; i <= dmax ; i ++ ) { if ( d [ i ] == 0 ) { System . out . println ( 0 ) ; return ; } } long ans = 1L ; for ( int i = 1 ; i <= dmax ; i ++ ) { long tmp = pow ( 2 , d [ i - 1 ] ) ; tmp = ( tmp + MOD - 1 ) % MOD ; ans = ( ans * pow ( tmp , d [ i ] ) ) % MOD ; ans = ( ans * pow ( 2 , ( long ) ( d [ i ] - 1 ) * d [ i ] / 2 ) ) % MOD ; } System . out . println ( ans ) ; } public static long pow ( long a , long n ) { long x = 1 ; while ( n > 0 ) { if ( n % 2 == 1 ) { x = x * a % MOD ; } a = a * a % MOD ; n >>= 1 ; } return x ; } }


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Thanks !! I am so ready for a good homegrown tomato . The squirrels and chipmunks have pulled almost all of ours . And ca n't wait to try your corn ! _____ From : Mills , Gail Sent : Monday , July NUM , NUM 9:46 AM To : Ellis , Regina ; Griffith , Pam ; Weed , Andrea ; Burton , Donna ; Beckett , Amanda Subject : Corn and Tomatoes for you in my office , come get what you want _____ CONFIDENTIAL : ATTORNEY/CLIENT PRIVILEGED ; ATTORNEY WORK PRODUCT The information contained in this email is intended for the individual or entity above . This email is protected by the Electronic Communications Privacy Act , NUM U.S.C. Sections NUM and is legally protected by the attorney/client privilege and/or work product doctrine . If you are not the intended recipient , please do not read , copy , use , forward or disclose this communication to others ; also , please notify the sender by replying to this message , and then delete this message from your system . Thank you . Circular NUM Notice - Regulations adopted by the Internal Revenue Service require us to inform you that any federal tax advice contained in this communication ( including attachments ) ( I ) is not intended or written by Burr & Forman LLP to be used , and can not be used , by any taxpayer for the purpose of avoiding penalties that may be imposed on the taxpayer , and ( II ) is not written to support the promotion or marketing of any transaction ( s ) or matter ( s ) addressed in this communication . Gail Livingston Mills Attorney at Law Direct : ( 205 ) 458-5300 Cell : ( 205 ) 616-9988 Main : ( 205 ) 251-3000 Fax : ( 205 ) 244-5681 420 North 20th Street , Suite 3400 Birmingham , Alabama 35203 www.burr.com < http://www.burr.com/ >


It would be nice , but not all mobile devices support a signature like that - I ' ve still got the original Droid - and another NUM months before the contract is up - and it wo n't do signatures . I would guess iPhones will handle signatures as well , but I 'm not sure how detailed . Probably something we should discuss at the next Tech Committee meeting - on those devices where we can require it , we probably should . I would actually like it because it is less obvious I 'm replying from my phone rather than the office . _____ From : Harlow , Tony Sent : Thursday , August NUM , NUM 12:55 PM To : Hayslip , Victor ; Vincent , India Subject : FW : New test See below for the signature I added to any email coming from my Droid . Do we need to have the same disclosure etc. . . that we have for emails coming from our outlook . With many of us communicating from our phones , should n't we require the same " Confidential ... " signature ? _____ CONFIDENTIAL : ATTORNEY/CLIENT PRIVILEGED ; ATTORNEY WORK PRODUCT The information contained in this email is intended for the individual or entity above . This email is protected by the Electronic Communications Privacy Act , NUM U.S.C. Sections NUM and is legally protected by the attorney/client privilege and/or work product doctrine . If you are not the intended recipient , please do not read , copy , use , forward or disclose this communication to others ; also , please notify the sender by replying to this message , and then delete this message from your system . Thank you . Circular NUM Notice - Regulations adopted by the Internal Revenue Service require us to inform you that any federal tax advice contained in this communication ( including attachments ) ( I ) is not intended or written by Burr & Forman LLP to be used , and can not be used , by any taxpayer for the purpose of avoiding penalties that may be imposed on the taxpayer , and ( II ) is not written to support the promotion or marketing of any transaction ( s ) or matter ( s ) addressed in this communication . _____ From : Hancock , Wes Sent : Thursday , August NUM , NUM 12:29 PM To : Harlow , Tony Subject : RE : New test That is awesome . is that from your driod ? Sent from my Android phone using TouchDown ( URL ) ----- Original Message ----- From : Harlow , Tony EMAIL ] Received : Thursday , NUM Aug NUM , 11:37 am To : Harlow , Tony EMAIL ] ; Hancock , Wes EMAIL ] Subject : RE : New test I am awesome ! Why is this print so small ? Anthony ( " Tony " ) Harlow Attorney at Law Direct : ( NUM ) NUM Main : ( NUM ) NUM Fax : ( NUM ) NUM NUM North NUM Street Suite NUM Birmingham , Alabama NUM URL < URL > _____ CONFIDENTIAL : ATTORNEY/CLIENT PRIVILEGED ; ATTORNEY WORK PRODUCT The information contained in this email is intended for the individual or entity above . This email is protected by the Electronic Communications Privacy Act , NUM U.S.C. Sections NUM and is legally protected by the attorney/client privilege and/or work product doctrine . If you are not the intended recipient , please do not read , copy , use , forward or disclose this communication to others ; also , please notify the sender by replying to this message , and then delete this message from your system . Thank you . Circular NUM Notice - Regulations adopted by the Internal Revenue Service require us to inform you that any federal tax advice contained in this communication ( including attachments ) ( I ) is not intended or written by Burr & Forman LLP to be used , and can not be used , by any taxpayer for the purpose of avoiding penalties that may be imposed on the taxpayer , and ( II ) is not written to support the promotion or marketing of any transaction ( s ) or matter ( s ) addressed in this communication . _____ From : Harlow , Tony Sent : Thursday , August NUM , NUM 11:37 AM To : Harlow , Tony ; Hancock , Wes Subject : New test Anthony ( " Tony " ) Harlow Attorney at Law Direct : ( NUM ) NUM Main : ( NUM ) NUM Fax : ( NUM ) NUM NUM North NUM Street Suite NUM Birmingham , Alabama NUM URL CONFIDENTIAL : ATTORNEY/CLIENT PRIVILEGED ; ATTORNEY WORK PRODUCT The information contained in this email is intended for the individual or entity above . This email is protected by the Electronic Communications Privacy Act , NUM U.S.C. Sections NUM and is legally protected by the attorney/client privilege and/or work product doctrine . If you are not the intended recipient , please do not read , copy , use , forward or disclose this communication to others ; also , please notify the sender by replying to this message , and then delete this message from your system . Thank you . Circular NUM Notice - Regulations adopted by the Internal Revenue Service require us to inform you that any federal tax advice contained in this communication ( including attachments ) ( I ) is not intended or written by Burr & Forman LLP to be used , and can not be used , by any taxpayer for the purpose of avoiding penalties that may be imposed on the taxpayer , and ( II ) is not written to support the promotion or marketing of any transaction ( s ) or matter ( s ) addressed in this communication . Anthony ( " Tony " ) Harlow Attorney at Law Direct : ( 205 ) 458-5122 Main : ( 205 ) 251-3000 Fax : ( 205 ) 278-9795 420 North 20th Street Suite 3400 Birmingham , Alabama 35203 www.burr.com < http://www.burr.com/ >


.... we are thankful ; Apologies I did not make time to speak at length with you . Burr & Forman - results matter < outbind : / / NUM : / / URL > _____ CONFIDENTIAL : ATTORNEY/CLIENT PRIVILEGED ; ATTORNEY WORK PRODUCT All previous disclaimers apply to this message as well . To see a full list of disclaimers that apply to email from URL visit : < URL > URL . _____ From : Mills , Gail Sent : Monday , August NUM , NUM 12:47 PM To : Meszaros , Erin ; Miles , L'Tanya S. Subject : RETREAT WAS GREAT !!! Gail Livingston Mills Attorney at Law Direct : ( NUM ) NUM Cell : ( NUM ) NUM Main : ( NUM ) NUM Fax : ( NUM ) NUM NUM North NUM Street , Suite NUM Birmingham , Alabama NUM URL < URL > _____ CONFIDENTIAL : ATTORNEY/CLIENT PRIVILEGED ; ATTORNEY WORK PRODUCT The information contained in this email is intended for the individual or entity above . This email is protected by the Electronic Communications Privacy Act , NUM U.S.C. Sections NUM and is legally protected by the attorney/client privilege and/or work product doctrine . If you are not the intended recipient , please do not read , copy , use , forward or disclose this communication to others ; also , please notify the sender by replying to this message , and then delete this message from your system . Thank you . Circular NUM Notice - Regulations adopted by the Internal Revenue Service require us to inform you that any federal tax advice contained in this communication ( including attachments ) ( I ) is not intended or written by Burr & Forman LLP to be used , and can not be used , by any taxpayer for the purpose of avoiding penalties that may be imposed on the taxpayer , and ( II ) is not written to support the promotion or marketing of any transaction ( s ) or matter ( s ) addressed in this communication . L'Tanya S. Miles Executive Assistant to CMO Direct : ( 404 ) 685-4283 Main : ( 404 ) 815-3000 Fax : ( 404 ) 214-7974 < mailto:llmiles@burr.comelicia > lmiles@burr.com 171 Seventeenth Street , NW Suite 1100 Atlanta , Georgia 30363 < http://www.burr.com/ > www.burr.com


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Myanmar 's pro-democracy leader Aung San Suu Kyi will return home late Friday but will remain in detention after recovering from surgery at a Yangon hospital , her personal physician said .

Myanmar 's pro-democracy leader Aung San Suu Kyi will be kept under house arrest following her release from a hospital where she underwent surgery , her personal physician said Friday .


Robert Walsh , 40 , remained in critical but stable condition Friday at Staten Island University Hospital 's north campus .

Walsh , also 40 , was in critical but stable condition at Staten Island University Hospital last night .


In fiction : Edward P. Jones ( " The Known World " ) and Scott Spencer ( " A Ship Made of Paper " ) .

The fifth nominee for fiction is Scott Spencer , for A Ship Made of Paper .


Because of the accounting charge , the company now says it lost $ 1.04 billion , or 32 cents a share , in the quarter ended June 30 .

Including the charge , the Santa Clara , Calif.-based company said Monday it lost $ 1.04 billion , or 32 cents per share , in the period ending June 30 .


The top rate will go to 4.45 percent for all residents with taxable incomes above $ 500,000 .

For residents with incomes above $ 500,000 , the income-tax rate will increase to 4.45 percent .


The S & P / TSX composite rose 87.74 points on the week , while the TSX Venture Exchange composite gained 44.49 points .

On the week , the Dow Jones industrial average rose 11.56 points , while the Nasdaq Stock Market gained 39.42 points .


Nearly 300 mutinous troops who seized a Manila shopping and apartment complex demanding the government resign gave up and retreated peacefully after some 19 hours .

Mutinous troops who seized a Manila shopping and apartment complex demanding the government resign ended a 19-hour standoff late Sunday and returned to barracks without a shot fired .


" Jeremy 's a good guy , " Barber said , adding : " Jeremy is living the dream life of the New York athlete .

He also said Shockey is " living the dream life of a New York athlete .


Carlson on Tuesday said he would not recuse himself from the case .

Service officials said Carlson refused to recuse himself from the case .


At community colleges , tuition will jump to $ 2,800 from $ 2,500 .

Community college students will see their tuition rise by $ 300 to $ 2,800 or 12 percent .


What is the step by step guide to invest in share market in india?

What is the step by step guide to invest in share market?


What is the story of Kohinoor (Koh-i-Noor) Diamond?

What would happen if the Indian government stole the Kohinoor (Koh-i-Noor) diamond back?


How can I increase the speed of my internet connection while using a VPN?

How can Internet speed be increased by hacking through DNS?


Why am I mentally very lonely? How can I solve it?

Find the remainder when [math]23^{24}[/math] is divided by 24,23?


Which one dissolve in water quikly sugar, salt, methane and carbon di oxide?


Astrology: I am a Capricorn Sun Cap moon and cap rising...what does that say about me?

I'm a triple Capricorn (Sun, Moon and ascendant in Capricorn) What does this say about me?


What keeps childern active and far from phone and video games?


What should I do to be a great geologist?


Motorola (company): Can I hack my Charter Motorolla DCX3400?

How do I hack Motorola DCX3400 for free internet?


What would be the reason there's an extra fee on my statement?


Is there a way I can get my ATM card back from the machine?


Why did my my transfer get declined?


Do you know why my card payment was reverted?


I'm concerned about a payment that has recently been made on my card.  I do not recognize the name that the transaction went to, can you help me?


As for limits are top ups included?


Can I top up with a cheque?


I found a charge for a direct debit that was not made by me.


The exchange rate on my purchase is wrong.


Can I resent my passcode?


Question: There are direct contractual links between who?

the architect's client and the main contractor


Question: What area was Kublai trying to capture by defending Xiangyang?


Question: Where is the home of the Sunnyside Country Club?


Question: What was the ideal duty of a concept engine?


Question: what do conquering people take away from native populations?


Question: Who may also submit private bills to Parliament?

an outside proposer
an outside proposer
an outside proposer


resumption of the session


i declare resumed the session of the european parliament adjourned on friday 17 december 1999 and i would like once again to wish you a happy new year in the hope that you enjoyed a pleasant festive period


although as you will have seen the dreaded 'millennium bug' failed to materialise still the people in a number of countries suffered a series of natural disasters that truly were dreadful


you have requested a debate on this subject in the course of the next few days during this partsession


in the meantime i should like to observe a minute' s silence as a number of members have requested on behalf of all the victims concerned particularly those of the terrible storms in the various countries of the european union


please rise then for this minute' s silence


(the house rose and observed a minute' s silence)


madam president on a point of order


you will be aware from the press and television that there have been a number of bomb explosions and killings in sri lanka


one of the people assassinated very recently in sri lanka was mr kumar ponnambalam who had visited the european parliament just a few months ago


``Alan is a superb local bathroom fitter and whilst he came across some problems with this job but he sorted them out straight away Alan is very honest and straight with his pricing and a good eye for detail!, no hidden costs`` - Mrs. D Sawyer
I designed and fitted the bathroom suite to suit this smaller room, Firstly taking out the existing suite,sourcing all the suite from a local Northampton plumbing supplier,newly plastered walls and with travertine effect ceramic tiles and anti-slip vinyl flooring. Plumbing in thermostatic shower valve with a 2.bar shower pump to create a luxurious shower.


A selection of images from the Birmingham & District Premiere Cricket League between Kidderminster Cricket Club and Walsall Cricket Club. Played at Chester Road Walsall CC won the game 207 All out (44.3). Kidderminster 205 All Out (49.3)


so, unless that's gonna be feasible, then ...


because he was probably just arrested at the moment by singh.


instead, he folded his arms and cocked his head, as if encouraging--or daring--kaye to continue.

instead, he folded his hands and cocked his head as kaye encouraged - or called for - to continue.


he reached for the microphone, and i heard his voice faint on the ship.

he reached for a microphone and i could hear his voice booming faintly throughout the ship.


she said it with such simple dignity until garion's throat tightened.

she said it with such simple dignity mat a lump caught in gar-ion's throat.


###############################################################################
##
##  Copyright (C) 2013-2014 Tavendo GmbH
##
##  Licensed under the Apache License, Version 2.0 (the "License");
##  you may not use this file except in compliance with the License.
##  You may obtain a copy of the License at
##
##      http://www.apache.org/licenses/LICENSE-2.0
##
##  Unless required by applicable law or agreed to in writing, software
##  distributed under the License is distributed on an "AS IS" BASIS,
##  WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
##  See the License for the specific language governing permissions and
##  limitations under the License.
##
###############################################################################

from autobahn.asyncio.websocket import WebSocketClientProtocol, \
                                       WebSocketClientFactory

import asyncio

class MyClientProtocol(WebSocketClientProtocol):

   def onConnect(self, response):
      print("Server connected: {0}".format(response.peer))

   @asyncio.coroutine
   def onOpen(self):
      print("WebSocket connection open.")

      ## start sending messages every second ..
      while True:
         self.sendMessage(u"Hello, world!".encode('utf8'))
         self.sendMessage(b"\x00\x01\x03\x04", isBinary = True)
         yield from asyncio.sleep(1)

   def onMessage(self, payload, isBinary):
      if isBinary:
         print("Binary message received: {0} bytes".format(len(payload)))
      else:
         print("Text message received: {0}".format(payload.decode('utf8')))

   def onClose(self, wasClean, code, reason):
      print("WebSocket connection closed: {0}".format(reason))

if __name__ == '__main__':

   import asyncio

   factory = WebSocketClientFactory("ws://localhost:9000", debug = False)
   factory.protocol = MyClientProtocol

   loop = asyncio.get_event_loop()
   coro = loop.create_connection(factory, '127.0.0.1', 9000)
   loop.run_until_complete(coro)
   loop.run_forever()
   loop.close()


from itertools import chain

from django.utils.itercompat import is_iterable

class Tags:
    """
    Built-in tags for internal checks.
    """
    admin = 'admin'
    caches = 'caches'
    compatibility = 'compatibility'
    database = 'database'
    models = 'models'
    security = 'security'
    signals = 'signals'
    templates = 'templates'
    urls = 'urls'

class CheckRegistry:

    def __init__(self):
        self.registered_checks = set()
        self.deployment_checks = set()

    def register(self, check=None, *tags, **kwargs):
        """
        Can be used as a function or a decorator. Register given function
        `f` labeled with given `tags`. The function should receive **kwargs
        and return list of Errors and Warnings.

        Example::

            registry = CheckRegistry()
            @registry.register('mytag', 'anothertag')
            def my_check(apps, **kwargs):
                # ... perform checks and collect `errors` ...
                return errors
            # or
            registry.register(my_check, 'mytag', 'anothertag')
        """
        kwargs.setdefault('deploy', False)

        def inner(check):
            check.tags = tags
            checks = self.deployment_checks if kwargs['deploy'] else self.registered_checks
            checks.add(check)
            return check

        if callable(check):
            return inner(check)
        else:
            if check:
                tags += (check, )
            return inner

    def run_checks(self, app_configs=None, tags=None, include_deployment_checks=False):
        """
        Run all registered checks and return list of Errors and Warnings.
        """
        errors = []
        checks = self.get_checks(include_deployment_checks)

        if tags is not None:
            checks = [check for check in checks if not set(check.tags).isdisjoint(tags)]
        else:
            # By default, 'database'-tagged checks are not run as they do more
            # than mere static code analysis.
            checks = [check for check in checks if Tags.database not in check.tags]

        for check in checks:
            new_errors = check(app_configs=app_configs)
            assert is_iterable(new_errors), (
                "The function %r did not return a list. All functions registered "
                "with the checks registry must return a list." % check)
            errors.extend(new_errors)
        return errors

    def tag_exists(self, tag, include_deployment_checks=False):
        return tag in self.tags_available(include_deployment_checks)

    def tags_available(self, deployment_checks=False):
        return set(chain.from_iterable(
            check.tags for check in self.get_checks(deployment_checks)
        ))

    def get_checks(self, include_deployment_checks=False):
        checks = list(self.registered_checks)
        if include_deployment_checks:
            checks.extend(self.deployment_checks)
        return checks

registry = CheckRegistry()
register = registry.register
run_checks = registry.run_checks
tag_exists = registry.tag_exists


"""
The :mod:`sklearn.utils` module includes various utilites.
"""

from collections import Sequence

import numpy as np
from scipy.sparse import issparse
import warnings

from .murmurhash import murmurhash3_32
from .validation import (as_float_array, check_arrays, safe_asarray,
                         assert_all_finite, array2d, atleast2d_or_csc,
                         atleast2d_or_csr, warn_if_not_float,
                         check_random_state)
from .class_weight import compute_class_weight

__all__ = ["murmurhash3_32", "as_float_array", "check_arrays", "safe_asarray",
           "assert_all_finite", "array2d", "atleast2d_or_csc",
           "atleast2d_or_csr", "warn_if_not_float", "check_random_state",
           "compute_class_weight"]

# Make sure that DeprecationWarning get printed
warnings.simplefilter("always", DeprecationWarning)

class deprecated(object):
    """Decorator to mark a function or class as deprecated.

    Issue a warning when the function is called/the class is instantiated and
    adds a warning to the docstring.

    The optional extra argument will be appended to the deprecation message
    and the docstring. Note: to use this with the default value for extra, put
    in an empty of parentheses:

    >>> from sklearn.utils import deprecated
    >>> deprecated() # doctest: +ELLIPSIS
    <sklearn.utils.deprecated object at ...>

    >>> @deprecated()
    ... def some_function(): pass
    """

    # Adapted from http://wiki.python.org/moin/PythonDecoratorLibrary,
    # but with many changes.

    def __init__(self, extra=''):
        """
        Parameters
        ----------
        extra: string
          to be added to the deprecation messages

        """
        self.extra = extra

    def __call__(self, obj):
        if isinstance(obj, type):
            return self._decorate_class(obj)
        else:
            return self._decorate_fun(obj)

    def _decorate_class(self, cls):
        msg = "Class %s is deprecated" % cls.__name__
        if self.extra:
            msg += "; %s" % self.extra

        # FIXME: we should probably reset __new__ for full generality
        init = cls.__init__

        def wrapped(*args, **kwargs):
            warnings.warn(msg, category=DeprecationWarning)
            return init(*args, **kwargs)
        cls.__init__ = wrapped

        wrapped.__name__ = '__init__'
        wrapped.__doc__ = self._update_doc(init.__doc__)
        wrapped.deprecated_original = init

        return cls

    def _decorate_fun(self, fun):
        """Decorate function fun"""

        msg = "Function %s is deprecated" % fun.__name__
        if self.extra:
            msg += "; %s" % self.extra

        def wrapped(*args, **kwargs):
            warnings.warn(msg, category=DeprecationWarning)
            return fun(*args, **kwargs)

        wrapped.__name__ = fun.__name__
        wrapped.__dict__ = fun.__dict__
        wrapped.__doc__ = self._update_doc(fun.__doc__)

        return wrapped

    def _update_doc(self, olddoc):
        newdoc = "DEPRECATED"
        if self.extra:
            newdoc = "%s: %s" % (newdoc, self.extra)
        if olddoc:
            newdoc = "%s\n\n%s" % (newdoc, olddoc)
        return newdoc

def safe_mask(X, mask):
    """Return a mask which is safe to use on X.

    Parameters
    ----------
    X : {array-like, sparse matrix}
        Data on which to apply mask.

    mask: array
        Mask to be used on X.

    Returns
    -------
        mask
    """
    mask = np.asanyarray(mask)
    if np.issubdtype(mask.dtype, np.int):
        return mask

    if hasattr(X, "toarray"):
        ind = np.arange(mask.shape[0])
        mask = ind[mask]
    return mask

def resample(*arrays, **options):
    """Resample arrays or sparse matrices in a consistent way

    The default strategy implements one step of the bootstrapping
    procedure.

    Parameters
    ----------
    `*arrays` : sequence of arrays or scipy.sparse matrices with same shape[0]

    replace : boolean, True by default
        Implements resampling with replacement. If False, this will implement
        (sliced) random permutations.

    n_samples : int, None by default
        Number of samples to generate. If left to None this is
        automatically set to the first dimension of the arrays.

    random_state : int or RandomState instance
        Control the shuffling for reproducible behavior.

    Returns
    -------
    Sequence of resampled views of the collections. The original arrays are
    not impacted.

    Examples
    --------
    It is possible to mix sparse and dense arrays in the same run::

      >>> X = [[1., 0.], [2., 1.], [0., 0.]]
      >>> y = np.array([0, 1, 2])

      >>> from scipy.sparse import coo_matrix
      >>> X_sparse = coo_matrix(X)

      >>> from sklearn.utils import resample
      >>> X, X_sparse, y = resample(X, X_sparse, y, random_state=0)
      >>> X
      array([[ 1.,  0.],
             [ 2.,  1.],
             [ 1.,  0.]])

      >>> X_sparse                   # doctest: +ELLIPSIS +NORMALIZE_WHITESPACE
      <3x2 sparse matrix of type '<... 'numpy.float64'>'
          with 4 stored elements in Compressed Sparse Row format>

      >>> X_sparse.toarray()
      array([[ 1.,  0.],
             [ 2.,  1.],
             [ 1.,  0.]])

      >>> y
      array([0, 1, 0])

      >>> resample(y, n_samples=2, random_state=0)
      array([0, 1])

    See also
    --------
    :class:`sklearn.cross_validation.Bootstrap`
    :func:`sklearn.utils.shuffle`
    """
    random_state = check_random_state(options.pop('random_state', None))
    replace = options.pop('replace', True)
    max_n_samples = options.pop('n_samples', None)
    if options:
        raise ValueError("Unexpected kw arguments: %r" % options.keys())

    if len(arrays) == 0:
        return None

    first = arrays[0]
    n_samples = first.shape[0] if hasattr(first, 'shape') else len(first)

    if max_n_samples is None:
        max_n_samples = n_samples

    if max_n_samples > n_samples:
        raise ValueError("Cannot sample %d out of arrays with dim %d" % (
            max_n_samples, n_samples))

    arrays = check_arrays(*arrays, sparse_format='csr')

    if replace:
        indices = random_state.randint(0, n_samples, size=(max_n_samples,))
    else:
        indices = np.arange(n_samples)
        random_state.shuffle(indices)
        indices = indices[:max_n_samples]

    resampled_arrays = []

    for array in arrays:
        array = array[indices]
        resampled_arrays.append(array)

    if len(resampled_arrays) == 1:
        # syntactic sugar for the unit argument case
        return resampled_arrays[0]
    else:
        return resampled_arrays

def shuffle(*arrays, **options):
    """Shuffle arrays or sparse matrices in a consistent way

    This is a convenience alias to ``resample(*arrays, replace=False)`` to do
    random permutations of the collections.

    Parameters
    ----------
    `*arrays` : sequence of arrays or scipy.sparse matrices with same shape[0]

    random_state : int or RandomState instance
        Control the shuffling for reproducible behavior.

    n_samples : int, None by default
        Number of samples to generate. If left to None this is
        automatically set to the first dimension of the arrays.

    Returns
    -------
    Sequence of shuffled views of the collections. The original arrays are
    not impacted.

    Examples
    --------
    It is possible to mix sparse and dense arrays in the same run::

      >>> X = [[1., 0.], [2., 1.], [0., 0.]]
      >>> y = np.array([0, 1, 2])

      >>> from scipy.sparse import coo_matrix
      >>> X_sparse = coo_matrix(X)

      >>> from sklearn.utils import shuffle
      >>> X, X_sparse, y = shuffle(X, X_sparse, y, random_state=0)
      >>> X
      array([[ 0.,  0.],
             [ 2.,  1.],
             [ 1.,  0.]])

      >>> X_sparse                   # doctest: +ELLIPSIS +NORMALIZE_WHITESPACE
      <3x2 sparse matrix of type '<... 'numpy.float64'>'
          with 3 stored elements in Compressed Sparse Row format>

      >>> X_sparse.toarray()
      array([[ 0.,  0.],
             [ 2.,  1.],
             [ 1.,  0.]])

      >>> y
      array([2, 1, 0])

      >>> shuffle(y, n_samples=2, random_state=0)
      array([0, 1])

    See also
    --------
    :func:`sklearn.utils.resample`
    """
    options['replace'] = False
    return resample(*arrays, **options)

def safe_sqr(X, copy=True):
    """Element wise squaring of array-likes and sparse matrices.

    Parameters
    ----------
    X : array like, matrix, sparse matrix

    Returns
    -------
    X ** 2 : element wise square
    """
    X = safe_asarray(X)
    if issparse(X):
        if copy:
            X = X.copy()
        X.data **= 2
    else:
        if copy:
            X = X ** 2
        else:
            X **= 2
    return X

def gen_even_slices(n, n_packs):
    """Generator to create n_packs slices going up to n.

    Examples
    --------
    >>> from sklearn.utils import gen_even_slices
    >>> list(gen_even_slices(10, 1))
    [slice(0, 10, None)]
    >>> list(gen_even_slices(10, 10))                     #doctest: +ELLIPSIS
    [slice(0, 1, None), slice(1, 2, None), ..., slice(9, 10, None)]
    >>> list(gen_even_slices(10, 5))                      #doctest: +ELLIPSIS
    [slice(0, 2, None), slice(2, 4, None), ..., slice(8, 10, None)]
    >>> list(gen_even_slices(10, 3))
    [slice(0, 4, None), slice(4, 7, None), slice(7, 10, None)]
    """
    start = 0
    for pack_num in range(n_packs):
        this_n = n // n_packs
        if pack_num < n % n_packs:
            this_n += 1
        if this_n > 0:
            end = start + this_n
            yield slice(start, end, None)
            start = end

def tosequence(x):
    """Cast iterable x to a Sequence, avoiding a copy if possible."""
    if isinstance(x, np.ndarray):
        return np.asarray(x)
    elif isinstance(x, Sequence):
        return x
    else:
        return list(x)

class ConvergenceWarning(Warning):
    "Custom warning to capture convergence problems"


#!/usr/bin/python
# encoding: utf-8 -*-

# Copyright: (c) 2013, Matthias Vogelgesang <matthias.vogelgesang@gmail.com>
# GNU General Public License v3.0+ (see COPYING or https://www.gnu.org/licenses/gpl-3.0.txt)

from __future__ import absolute_import, division, print_function
__metaclass__ = type

ANSIBLE_METADATA = {'metadata_version': '1.1',
                    'status': ['preview'],
                    'supported_by': 'community'}

DOCUMENTATION = '''
---
module: kernel_blacklist
author:
- Matthias Vogelgesang (@matze)
version_added: '1.4'
short_description: Blacklist kernel modules
description:
    - Add or remove kernel modules from blacklist.
options:
    name:
        description:
            - Name of kernel module to black- or whitelist.
        required: true
    state:
        description:
            - Whether the module should be present in the blacklist or absent.
        choices: [ absent, present ]
        default: present
    blacklist_file:
        description:
            - If specified, use this blacklist file instead of
              C(/etc/modprobe.d/blacklist-ansible.conf).
'''

EXAMPLES = '''
- name: Blacklist the nouveau driver module
  kernel_blacklist:
    name: nouveau
    state: present
'''

import os
import re

from ansible.module_utils.basic import AnsibleModule

class Blacklist(object):
    def __init__(self, module, filename, checkmode):
        self.filename = filename
        self.module = module
        self.checkmode = checkmode

    def create_file(self):
        if not self.checkmode and not os.path.exists(self.filename):
            open(self.filename, 'a').close()
            return True
        elif self.checkmode and not os.path.exists(self.filename):
            self.filename = os.devnull
            return True
        else:
            return False

    def get_pattern(self):
        return r'^blacklist\s*' + self.module + '$'

    def readlines(self):
        f = open(self.filename, 'r')
        lines = f.readlines()
        f.close()
        return lines

    def module_listed(self):
        lines = self.readlines()
        pattern = self.get_pattern()

        for line in lines:
            stripped = line.strip()
            if stripped.startswith('#'):
                continue

            if re.match(pattern, stripped):
                return True

        return False

    def remove_module(self):
        lines = self.readlines()
        pattern = self.get_pattern()

        if self.checkmode:
            f = open(os.devnull, 'w')
        else:
            f = open(self.filename, 'w')

        for line in lines:
            if not re.match(pattern, line.strip()):
                f.write(line)

        f.close()

    def add_module(self):
        if self.checkmode:
            f = open(os.devnull, 'a')
        else:
            f = open(self.filename, 'a')

        f.write('blacklist %s\n' % self.module)

        f.close()

def main():
    module = AnsibleModule(
        argument_spec=dict(
            name=dict(type='str', required=True),
            state=dict(type='str', default='present', choices=['absent', 'present']),
            blacklist_file=dict(type='str')
        ),
        supports_check_mode=True,
    )

    args = dict(changed=False, failed=False,
                name=module.params['name'], state=module.params['state'])

    filename = '/etc/modprobe.d/blacklist-ansible.conf'

    if module.params['blacklist_file']:
        filename = module.params['blacklist_file']

    blacklist = Blacklist(args['name'], filename, module.check_mode)

    if blacklist.create_file():
        args['changed'] = True
    else:
        args['changed'] = False

    if blacklist.module_listed():
        if args['state'] == 'absent':
            blacklist.remove_module()
            args['changed'] = True
    else:
        if args['state'] == 'present':
            blacklist.add_module()
            args['changed'] = True

    module.exit_json(**args)

if __name__ == '__main__':
    main()