
import dataclasses
import re
import string
from typing import Any, Dict, Iterator, List, Mapping, Optional, Sequence, Tuple

import numpy as np

from . import residue_constants


A     :	Any    = Mapping[str, np.ndarray]
A     :	Any    = Mapping[str, Any]  # Is a nested dict.
A     :	Union[str, Any]    = 0.01







@dataclasses.dataclass(frozen=a			)
class 			__A:
				snake_case_						   =    42  # [num_res, num_atom_type, 3]

				# Amino-acid type for each residue represented as an integer between 0 and
				# 20, where 20 is 'X'.
				snake_case_						   =    42  # [num_res]

				# Binary float mask to indicate presence of a particular atom. 1.0 if an atom
				# is present and 0.0 if not. This should be used for loss masking.
				snake_case_						   =    42  # [num_res, num_atom_type]

				# Residue index as used in PDB. It is not necessarily continuous or 0-indexed.
				snake_case_						   =    42  # [num_res]

				# B-factors, or temperature factors, of each residue (in sq. angstroms units),
				# representing the displacement of the residue from its ground truth mean
				# value.
				snake_case_						   =    42  # [num_res, num_atom_type]

				# Chain indices for multi-chain predictions
				snake_case_						   =    None

				# Optional remark about the protein. Included as a comment in output PDB
				# files
				snake_case_						   =    None

				# Templates used to generate this protein (prediction-only)
				snake_case_						   =    None

				# Chain corresponding to each parent
				snake_case_						   =    None



def     __lowerCAmelCase			(			a__  )       ->  Protein:
				__a										=    R'''(\[[A-Z]+\]\n)'''
				__a										=    [tag.strip() for tag in re.split(a__						,    a__  ) if len(a__  ) > 0]
				__a										=    zip(tags[0::2]						,    [l.split('''\n'''  ) for l in tags[1::2]]  )

				__a										=    ["N", "CA", "C"]
				__a										=    None
				__a										=    None
				__a										=    None
				for g in groups:
								if "[PRIMARY]" == g[0]:
												__a										=    g[1][0].strip()
												for i in range(len(a__  )  ):
																if seq[i] not in residue_constants.restypes:
																				__a										=    '''X'''  # FIXME: strings are immutable
												__a										=    np.array(
												    [residue_constants.restype_order.get(a__						,    residue_constants.restype_num  ) for res_symbol in seq]  )
								elif "[TERTIARY]" == g[0]:
												__a										=    []
												for axis in range(3  ):
																tertiary.append(list(map(a__						,    g[1][axis].split()  )  )  )
												__a										=    np.array(a__  )
												__a										=    np.zeros((len(tertiary[0]  ) // 3, residue_constants.atom_type_num, 3)  ).astype(np.floataa  )
												for i, atom in enumerate(a__  ):
																__a										=    np.transpose(tertiary_np[:, i::3]  )
												atom_positions *= PICO_TO_ANGSTROM
								elif "[MASK]" == g[0]:
												__a										=    np.array(list(map({'''-''': 0, '''+''': 1}.get						,    g[1][0].strip()  )  )  )
												__a										=    np.zeros(
												    (
												        len(a__  ),
												        residue_constants.atom_type_num,
												    )  ).astype(np.floataa  )
												for i, atom in enumerate(a__  ):
																__a										=    1
												atom_mask *= mask[..., None]

				assert aatype is not None

				return Protein(
				    atom_positions=a__						,    atom_mask=a__						,    aatype=a__						,    residue_index=np.arange(len(a__  )  )						,    b_factors=a__						,    )


def     __lowerCAmelCase			(			a__						,    a__ = 0  )       ->  List[str]:
				__a										=    []

				__a										=    prot.remark
				if remark is not None:
								pdb_headers.append(F"""REMARK {remark}"""  )

				__a										=    prot.parents
				__a										=    prot.parents_chain_index
				if parents is not None and parents_chain_index is not None:
								__a										=    [p for i, p in zip(a__						,    a__  ) if i == chain_id]

				if parents is None or len(a__  ) == 0:
								__a										=    ['''N/A''']

				pdb_headers.append(F"""PARENT {' '.join(a__  )}"""  )

				return pdb_headers


def     __lowerCAmelCase			(			a__						,    a__  )       ->  str:
				__a										=    []
				__a										=    pdb_str.split('''\n'''  )

				__a										=    prot.remark
				if remark is not None:
								out_pdb_lines.append(F"""REMARK {remark}"""  )

				__a										=    42
				if prot.parents is not None and len(prot.parents  ) > 0:
								__a										=    []
								if prot.parents_chain_index is not None:
												__a										=    {}
												for p, i in zip(prot.parents						,    prot.parents_chain_index  ):
																parent_dict.setdefault(str(a__  )						,    []  )
																parent_dict[str(a__  )].append(a__  )

												__a										=    max([int(a__  ) for chain_idx in parent_dict]  )
												for i in range(max_idx + 1  ):
																__a										=    parent_dict.get(str(a__  )						,    ['''N/A''']  )
																parents_per_chain.append(a__  )
								else:
												parents_per_chain.append(list(prot.parents  )  )
				else:
								__a										=    [['''N/A''']]

				def make_parent_line(a__  ) -> str:
								return F"""PARENT {' '.join(a__  )}"""

				out_pdb_lines.append(make_parent_line(parents_per_chain[0]  )  )

				__a										=    0
				for i, l in enumerate(a__  ):
								if "PARENT" not in l and "REMARK" not in l:
												out_pdb_lines.append(a__  )
								if "TER" in l and "END" not in lines[i + 1]:
												chain_counter += 1
												if not chain_counter >= len(a__  ):
																__a										=    parents_per_chain[chain_counter]
												else:
																__a										=    ['''N/A''']

												out_pdb_lines.append(make_parent_line(a__  )  )

				return "\n".join(a__  )


def     __lowerCAmelCase			(			a__  )       ->  str:
				__a										=    residue_constants.restypes + ['''X''']

				def res_atoa(a__  ) -> str:
								return residue_constants.restype_atoa.get(restypes[r]						,    '''UNK'''  )

				__a										=    residue_constants.atom_types

				__a										=    []

				__a										=    prot.atom_mask
				__a										=    prot.aatype
				__a										=    prot.atom_positions
				__a										=    prot.residue_index.astype(np.intaa  )
				__a										=    prot.b_factors
				__a										=    prot.chain_index

				if np.any(aatype > residue_constants.restype_num  ):
								raise ValueError('''Invalid aatypes.'''  )

				__a										=    get_pdb_headers(a__  )
				if len(a__  ) > 0:
								pdb_lines.extend(a__  )

				__a										=    aatype.shape[0]
				__a										=    1
				__a										=    0
				__a										=    string.ascii_uppercase
				__a										=    None
				# Add all atom sites.
				for i in range(a__  ):
								__a										=    res_atoa(aatype[i]  )
								for atom_name, pos, mask, b_factor in zip(a__						,    atom_positions[i]						,    atom_mask[i]						,    b_factors[i]  ):
												if mask < 0.5:
																continue

												__a										=    '''ATOM'''
												__a										=    atom_name if len(a__  ) == 4 else F""" {atom_name}"""
												__a										=    ''''''
												__a										=    ''''''
												__a										=    1.00
												__a										=    atom_name[0]  # Protein supports only C, N, O, S, this works.
												__a										=    ''''''

												__a										=    '''A'''
												if chain_index is not None:
																__a										=    chain_tags[chain_index[i]]

												# PDB is a columnar format, every space matters here!
												__a										=    (
												    F"""{record_type:<6}{atom_index:>5} {name:<4}{alt_loc:>1}"""
												    F"""{res_name_a:>3} {chain_tag:>1}"""
												    F"""{residue_index[i]:>4}{insertion_code:>1}   """
												    F"""{pos[0]:>8.3f}{pos[1]:>8.3f}{pos[2]:>8.3f}"""
												    F"""{occupancy:>6.2f}{b_factor:>6.2f}          """
												    F"""{element:>2}{charge:>2}"""
												)
												pdb_lines.append(a__  )
												atom_index += 1

								__a										=    i == n - 1
								if chain_index is not None:
												if i != n - 1 and chain_index[i + 1] != prev_chain_index:
																__a										=    True
																__a										=    chain_index[i + 1]

								if should_terminate:
												# Close the chain.
												__a										=    '''TER'''
												__a										=    (
												    F"""{chain_end:<6}{atom_index:>5}      {res_atoa(aatype[i]  ):>3} {chain_tag:>1}{residue_index[i]:>4}"""
												)
												pdb_lines.append(a__  )
												atom_index += 1

												if i != n - 1:
																# "prev" is a misnomer here. This happens at the beginning of
																# each new chain.
																pdb_lines.extend(get_pdb_headers(a__						,    a__  )  )

				pdb_lines.append('''END'''  )
				pdb_lines.append(''''''  )
				return "\n".join(a__  )


def     __lowerCAmelCase			(			a__  )       ->  np.ndarray:
				return residue_constants.STANDARD_ATOM_MASK[prot.aatype]






def     __lowerCAmelCase			(			a__						,    a__						,    a__ = None						,    a__ = None						,    a__ = None						,    a__ = None						,    a__ = None						,    )       ->  Protein:
				return Protein(
				    aatype=features['''aatype''']						,    atom_positions=result['''final_atom_positions''']						,    atom_mask=result['''final_atom_mask''']						,    residue_index=features['''residue_index'''] + 1						,    b_factors=b_factors if b_factors is not None else np.zeros_like(result['''final_atom_mask''']  )						,    chain_index=a__						,    remark=a__						,    parents=a__						,    parents_chain_index=a__						,    )

from __future__ import annotations

import typing
from collections import Counter


def     __lowerCAmelCase			(			a__  )       ->  typing.Counter[int]:
				__a										=    Counter()
				for base in range(1						,    max_perimeter + 1  ):
								for perpendicular in range(a__						,    max_perimeter + 1  ):
												__a										=    (base * base + perpendicular * perpendicular) ** 0.5
												if hypotenuse == int(a__  ):
																__a										=    int(base + perpendicular + hypotenuse  )
																if perimeter > max_perimeter:
																				continue
																triplets[perimeter] += 1
				return triplets


def     __lowerCAmelCase			(			a__ = 1000  )       ->  int:
				__a										=    pythagorean_triple(a__  )
				return triplets.most_common(1  )[0][0]


if __name__ == "__main__":
					print(F"Perimeter {solution()} has maximum solutions")