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<< Back to BFS Home
Impacting Generations

BFS is a company
made of stories.
Stories of teams and individuals Taking Charge and reaching their maximum potential.
Lets Hear Your Story

Looking back at 1,000s of stories on the impact the BFS Program has had on so many we feel we need a space to share them, and inspire future successes. We are launching the "Impacting Generations" initiative to do just that.
For over 35 years BFS has been in the forefront of teaching coaches and young athletes how to get the most out of themselves, and their teams - on and off the field. Winning championships is a huge part of the what the BFS Total Program is about, but winning in life is an even larger part of the BFS message. We firmly believe that through athletics and physical education, in all it's many forms, every young person can grow to be a more complete and prepared person for life's goals and dreams.
BFS has been collecting and printing many of these stories in the BFS Magazine for years and proudly highlighting the BFS Male and Female "Athletes of the Year" as well as the "High School of the Year" within those pages. In fact the entire history of the BFS Magazine is available online in the BFS Archives for free and is a great resource for motivation. However we realize that we can only feature a small portion of the stories of BFS in our publications. And there are so many more stories.
So this year we are bringing to life the "Impacting Generations" page at www.biggerfasterstronger.com/impact. Through the use of all the new channels available for sharing our experiences including Facebook, Twitter, YouTube and of course Email, we will bring together your stories to help inspire others to reach their full potential.

It is the stories of all the people, students, athletes, coaches, parents and administrators, that we have impacted positively which inspiresus here at BFS. These are the results which motivate us to keep doing the absolute best we can to help you reach for that championship ring on the field of play and in life!

Click here and share your story with BFS…
Impacting Generations

Your stories shared with BFS may be published on this page and in other BFS materials both electronic and print.

Bloomfield High School, NJ

Dear BFS,

Mike Carter from Bllomfield, NJ here. Just thought I would give you an update about my son Michael you meet when you were here several years ago, Mike graduates tomorrows night form Bloomfield High. He will Graduate with a GPA of 3.8+ and in top 20 percent of his class of over 400.

Mike was a two sport captain in football and baseball(2 years). Mike was a 2 year stater and was part of a very solid group of seniors that help bring Bloomfield to their first state championship game in many years. As QB he threw for 20 TD and ran for another10. The offense had over 35oo yards total yards. Mike was named player of the year for a sidelinechatter.com. they cover several counties in Northern New Jersey.In baseball,Mike played centerfield and was a four year starter who became the school and county all time hit leader with 152 career hits.He hit over .450 as a senior and had a carrer 411 average for 370 career at bats. Mike was named county player of the year as well as by sideleinechatter.com.

Mike also really gets after it in the weight room. At 5'9 175 lbs, Mike is able to bench 295, squat 385 lbs, power clean 255, and deadlift 405 lbs .Mike will attend Rutgers University on a baseball scholarship.

Had the pleasure of a life time to coach Mike in football. Could not be any prouder.

Thanks for your time

Mike Carter, HFC Bloomfield NJ

Colby High School

Dear BFS,

We completed the season with a trip to the state semi-finals losing to the eventual state champs. We lost two games during our conference schedule but avenged one of them with a victory in a play-offf game. The other loss came at the hands of a state final participant in another division. Overall I was very proud of how we played. I felt like we improved as the season went along as we only had two returners on offense and three on defense. We will begin workouts after Thanksgiving and some of the kids are alread asking when they can begin.

I talked to Dennis Moon at the state games and he informed me he was now working for you guys. He is a good man and I'm sure it will work out well. He also mentioned that you are poised to take the reins at BFS. Congratulations and I'm sure the best is yet to come for the company.

Jeff Rosemeyerl

Colby High School

Zanesville High School

Dr. Shepard visited our school in the late 90's when we started our run of winning in Ohio high school boys basketball. Dr. Shepard had such great energy and passion that day and he really left a great impression on our kids and staff. We were featured in the magazine during that time as well as my son Logan, who will be playing his final year of college basketball at Maryland this year.

Scott Aronhalt
Athletic Director

Great commitment from Pope John Paul II High School in Hyannis, MA - We expect some great results from their work ethic in their new BFS Weight room!

Greg Streit, Technology Education
Assistant Football / Track - Edgar High School, Edgar, WI

BFS Clinicians, I am writing to you to tell you the success of our athletic programs here at Edgar High School that are using the BFS program. We use this program religiously in our summer school fitness class, and throughout our football and track season and we have had your clinicians here at least twice in the past. Our footbal lteam has gone 41-1 over the past three years winning two state championships and one runner up. Our girls track and field team has won two state championship sin a row and were runner ups in 2008. They have also become the first team in Wisconsin state history to score over 100 points at the state track and field meet. Not only did they score 114 points in 2010, they repeated that performance with 108 points in 2011. We would love to do a story on these programs to be featured in your BFS magazine that your company publishes. Our student athletes have bought into your program and it has made all the difference in our athletic programs. Thanks for your time and we hope to hear from you at some time.

BFS Be An 11 Presentation

Mike Zeller - Lenoir City Schools

Hey John, We ended up 7-6 with some big upsets. Beat Farragut, a school twice our size and who we call "the chosen ones," in the 9th week to qualify for the playoffs. Beat the defending 5A State Champions in the first round 34-30. We drove the ball 80 yards five times. Won our second round 26-12. Got put out in the quarterfinals 34-26 by an undefeated team that ended up losing in the Championship game by 4 points. Good news is we have 15 returning starters. 9 on offense.

With that said, check your calendar for the weekend of April 13/14. Definitely would like to bring you here for a Be 11 clinic, possibly the

2 Day deal. Let me know what your schedule looks like. Hope things are well with you and your family. God Bless, Mike Zeller

Chris and Cory Klem

This quote is from Chris Klem, his son is Freshman HS Football Player Cory Klem. In Indiana, Cory is one of the Top Football players in his Class. He was one of only a handful of players selected to attend the FBU Top Gun Camp in West Virgina this past summer.
"To do BFS, is to BELIEVE - Cory believes he can accomplish every goal he sets, because of BFS, he also understands and is willing to do the work to achieve his goals". Chris Klem

Mighty Titans Scotty Delong TYFL President an Football Parent

Beginning with the current 8th grade group when they were 6th graders and continuing all the way down to our current 6th graders, the TYFL has been amazingly successful in play outside our regular league play against ALL opponents, many of which we will play as part of our Jr. High or High School schedules, but also much larger schools and clubs from around the country. The Secret for all three groups (6th - 8th) is undeniably the Bigger Faster Stronger(BFS)State Championship Club created and spear headed by BFS Clinician Coach Sellers. These boys began a very basic physical conditioning/ football knowledge program based the key parts of the BFS program as 4th graders that evolves into a full blown BFS strength an conditioning program by the time they are 9th graders. In this program they create a PHYSICAL AND MENTAL "gap" that when compared to schools that begin their strength programs as freshman, cannot be overcome. The difference is clear on the football field and is apparent to even the untrained eye how we completely physically dominate each and every opponent. However, more importantly than the strength gains, is the trust, loyalty, accountability and belief they will be good enough to win a 3A state championship in football.These qualities were developed with the BFS "Be an 11" program. When the boys see each other at least one time per week, putting in the time and effort, doing the same things, and improving toward the same dream both physically and mentally, they are building a TEAM dynamic that has a strong psychological effect on making them want to stay together. In a 3A program numbers retention is as important as anything else we do and this program is helping us do just that. It has been AMAZING! TYFL = Titan Youth Football League, feeder program for Gibson Southern HS in Southern Indiana. Home of the Mighty Titans Scotty Delong TYFL President an Football Parent

The BFS WRSC is your passport to the next level!
From program info to safety and spotting protocols, BFS has the knowledge to build your championship program. Check the BFS Calendar for Certifications near you !

Dont forget to follow us on twitter or friend us up at facebook

facebook twitter

For more info visit www.biggerfasterstronger.com or call 800-628-9737


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Top Green Tips to Afford Going Green

Top Ten Ways to Afford Going GreenWant to go green but think it’s too expensive? Think again. You can actually SAVE $20-$50 every month by choosing products and services that protect the planet. These green tips show you how:

Buy reusables. Compare a sponge to a roll of paper towels. One sponge may cost as little as $.99. A roll of paper towels runs around $1.99. But one sponge lasts as long as SEVENTEEN ROLLS of paper towels. You could save as much as $33 in paper towels before you have to throw the sponge away. (Meanwhile, keep sponges fresh by washing in the dishwasher with the dishes; microwave on high heat for 30 seconds to kill germs.)

Switch to compact fluorescent light bulbs. The CFLs may cost $2-4 more thanTop Ten Ways to Afford Going Green the incandescent bulb you’re used to. But the CFL uses 66% less energy and lasts ten times as long. So over the course of the lifetime of the bulb, you can save as much as $30-$50 on electricity. Plus – think of all the time you’re saving changing light bulbs. (NOTE: Choose Energy Star-rated bulbs and don’t turn them on and off frequently to make them last longest.)

Forget bottled water. When you buy bottled water, you’re buying a plastic bottle, a label, the energy to transport the bottle to your store, a bottle cap, and the water inside the bottle — which, almost half the time, is actually tap water! And even though water is very cheap when it flows out of your tap, it can cost as much as 10,000 times more when it’s served in a bottle. Buy a reusable water bottle and fill it up at your own tap. If you’re worried about water quality, use the money you save on bottled water to buy a filter for your faucet.

Top Ten Ways to Afford Going GreenSave gas. This sounds like a “no brainer,” but you’d be surprised how many people waste gas – and money. Pump up your car tires to improve fuel efficiency by 3.3%. Use cruise control for as much as a 14% fuel efficiency gain. Go to Gas Buddy to find the cheapest gas in your driving range. Car pool to share driving costs with others. Consider these other tips.

Buy in bulk. You pay nearly twice the price for the same weight when you buy small, individually wrapped servings of a product rather than the bulk size. Laundry detergent, fabric softener, dishwasher detergent, shampoo, soap, conditioner, snacks, soft drinks and many other items offer a bulk or ‘economy’ size. Even buying a half-gallon container of juice is cheaper than buying individual juice boxes.

Plug into a power strip. 40 percent of the energy used to power consumer electronics is devoured when the devices are turned off. That’s nearly 5 percent of the total electricity American homes consume. A power strip lets you plug several appliances or lots of office equipment into one larger outlet that you can turn off with minimal hassle, automatically cutting power to all devices that are plugged into it.

Take a tax credit. New fuel-efficient hybrid vehicles save gas and earn you tax credits, too. The amount, as determined by the IRS, ranges from $250 to $3150.

Use Craig’s List or Freecycle. Before you pay full price for furniture, appliances, sporting equipment or lawn and garden tools, go “shopping” online – at clearinghouses that help you acquire the goods you need at no or low cost. In the same vein, get books from libraries, or swap bought books with friends. Trade in your gently worn clothes at thrift stores, and pocket the savings or apply to the purchase of something equally thrifty.

Top Ten Ways to Afford Going GreenDonate. Giving your used clothing and household goods to the Salvation Army, your local church, or a local charity for veterans lightens the load at the landfill and earns you a tax write-off for your charitable donations.

Choose quality over quantity. Simplify your needs overall. Then, buy clothes, jewelry, toys, tools, furniture and other commodities that are made to last. You may spend a few more dollars up front but save money in the long run when you don’t need to replace items that break or wear out quickly.

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Bil Browning

Dead frat pledge covered in anti-gay slurs

Filed By Bil Browning | January 11, 2007 5:25 PM | comments

Filed in: Living
Tags: frat boys, homophobic behavior, Obituary, Texas

An 18 year old freshman at the University of Texas in Austin was found dead of alcohol poisoning after a frathouse pledge party. While that may not be too surprising, a recently released medical examiner's report did shock the community.

The pledge was found with numerous anti-gay slurs and obscene drawings on his body - done while he lay dying. Phanta "Jack" Phoummarath's family has told the media that he wasn't gay. His blood alcohol level was .41

A tragedy, to be sure. And made even more obscene by the homophobic and bigoted scrawls they decorated him with instead of seeking medical attention on his behalf.

Phoumarrath was found dead the day after the party, his body still in the fraternity bedroom in which he passed out the night before.

Dr. Roberto Bayardo of the medical examiner's office reported that party-goers had used green and black markers to write "FAG," "I'm gay" and "I AM FAT" on Phoummarath's head, face, torso, legs and feet. Someone also added several drawings depicting naked men and women on his body and blackened his toenails.

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Why You Should Blog Every Single Day

Do you check your email every single day? Or, if it’s your work email, do you check your email every day? Or maybe you have your email open all the time, like me. At least why you are working? Well, if you are active online, run an online business, and answer emails and your phone, then there’s no reason why you shouldn’t blog every day. Or at least post “something” each and every day. Why? By keeping your website (and your blog) active, you’re telling everyone: not only the search engines, but real humans, that you are alive and well, your business is thriving, and you are there for them: your customers. [Read more…]

Easter Bunny Kicked Out of PRWeb Press Release Web Site

The Easter Bunny has officially been kicked out of PRWeb, the popular press release web site. According to Standing Dog’s latest blog post, the Easter Bunny could not be included in a recent press release due to the fact that the Easter Bunny is “parodic”.

The popular press release distribution service recently contacted Standing Dog Interactive in regards to a pending press release that dealt with an Easter brunch. Writers at the Dallas-based interactive marketing agency were shocked to learn that the Easter Bunny was deemed “parodic” and could not be mentioned in an introduction, tongue-in-cheek be damned.

According to the editors at Vocus, they did not feel that it was correct to mention the Easter Bunny in a press release–although the mention of the Easter Bunny in this case was related to an Easter promotion that was being done at a hotel.

Do You Have a Plan for Social Media Crisis Management?

Social Media Crisis Management

If you have a social media team at your company, or you have someone who is handling the social media accounts for your brand and your business, then you probably should have a plan for social media crisis management. If there is an issue that comes up all of a sudden that must be addressed, do you have a plan in place to handle it? [Read more…]


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Old 10-06-2010, 04:40 PM
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shenecke shenecke is offline
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Originally Posted by bluebee View Post
Tom, over at EAS, says you have to in order to "reboot" the DICE.

Worse yet, you have to short the battery at least once a week because that's how often my DICE locks up.
I would smash that Dice! What a piece of s&%t!
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Old 11-17-2011, 08:28 AM
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Originally Posted by Griffoun View Post

If you're talking about Latitude, it says I have no history.

And people like FourSquare and Facebook and doing check-ins all over the place.... which I can never understand.
There you can see every Youtube video you have seen,every Google search you have done,every location you have searched on Google Maps,copy of every contact in your contact book,every Google Device you have used,etc..
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Originally Posted by 16n69 View Post
I really don't give a rat's a$$ what you or anyone else the time I was impressed and thrilled to get an early preview of the cars...I am a fan of BMW and maybe I did over react...I want to always like a new bimmer...but they have made that increasingly more difficult...the F30 SUCKS compared to Bimmers past...period.
You are certainly welcome to your new and improved opinion, but the raw numbers point to the F30 being an improvement in a great many measurable ways.
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Old 11-13-2012, 10:39 PM
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Originally Posted by Hemorrhage View Post
Anyway...I drove it like Clarkson.

Fixed your post

I'm not expert - but it dying like that and then taking off could be a sign it wasn't doing well to begin with....

Did I cause this? Or were the weird launches an early sign of the turbo dying
Yes to both questions. You did drive it around for 30 minutes first so it was all the way warmed up, right????
The models and equipment (standard and optional) illustrated in this post reflect my misunderstanding of vehicles supplied by BMW AG to the German market. In other EU member states, the truthyness of my posts may vary. Please ignore this post. Subject to change.

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Old 01-17-2013, 11:39 AM
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Originally Posted by moviebumm View Post
I think the 2014 lexus IS looks decent although similar to the current IS. The problem with the current IS much like most of the other Lexus models is that they do not drive well. I will have to reserve judgement until I drive a 2014 IS but when I decide the time is right to get a new car, the F30 however will be on the top of my list while the IS is at the bottom.
If the new IS hnaldes anything like the new GS, the F30 will have take a backseat to it.
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Image Analysis software wanted

Brian Olson olsonb at
Sun Feb 14 19:18:53 EST 1999

Yes, I'd like to find freeware.  Basically I just want a program that will determine the number of objects in an image.  Something that
I could set thresholds on size, etc.
Do you know of any commercial software available?

Charles Schneider #3254 wrote:

> In article <FB9B72FA9A235C95.D1D9E8DC9C3D2036.6AF4DE27F9BF9B8C at>, Brian Olson <olsonb at> writes:
> |> I am looking for software that will quantify aphids scanned with a
> |> desktop scanner.  Any helpful hints would be appreciated.
> |> Thanks
> |>
> Freeware or not?
> --
> CS
> reponse : oter nsp dans mon adresse.
> reply : remove nsp in my address.

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text:
Mechanical stress and lignification

Tony Travis ajt at
Thu Apr 2 13:08:42 EST 1992

mwfolsom at (Mike Folsom) writes:
: [...]
: Such a heavy question for April's fool day -

I realised the date when I posted the question ;-)

It _is_ a serious question though!

: Oh well, since you insist -
: Have you buzzed through the plant defense literature?  Seems
: to me that lignification is one of the mechanisms plants use
: to defend against pathogens.  Now how different is this from the

No, but you are right because I have seen reference to this in the
'physiology' literature in relation to lignification and turgor
maintenance during water stress.

: production of lignin in response to mechanical stress?  I seem to
: remember that people who do research in the area of plant
: defense mechanisms often use mechanical techniques, e.g.
: sandpaper, grinding powerders, etc, to induce plant responses.
: I guess I'm wondering if the same techniques used to analyze
: plant defense responses could be applied to the questions
: which interest you.
: Are we on the same wavelength?

Yes we are.

The mechanical techniques you mention are intended to breach the cuticle
aren't they?

What I'm interested in knowing is do varieties that exhibit resistance
to lodging damage (falling over) have genetic characteristics that
result in thicker and more lignified cell walls, or do they have the
ability to adapt to mechanical (bending) stress by increasing the rate
of cell wall deposition and/or lignification in response to a
mechanical stimulus such as the load from leaves in the canopy blowing
about in the wind.

I studied forestry many years ago and I remember that trees produce
'reaction' wood if the soil they are growing in gives way making the
trunk lean over.  The wood is produced at the point of greatest
mechanical stress and is not simply a geotropic response.  I'm
interested to know if this is a response to a mechanical stimulus like,
for example, the response of Mimosa pudica to the impact of raindrops
on its leaves (I'm not suggesting it is the same mechanism though).

We are investigating the differences in anatomy of maize varieties in
our lab, but we are using samples from mature plants.  I wondered if
some of the differences we see are evidence of adaptation.  This is
important because lignification, in general, reduces the usefulness of
crop plants that are used to feed animals.

If plants can be selected for their ability to adapt to mechanical
stress when lodging is likely, the extent of lignification would be
reduced under conditions where lodging is less likely to occur because
the mechanical stress would be absent.  At present, varieties that are
known to resist lodging damage are thought to do so because of more
robust anatomy (thicker and more lignified sclerenchyma in particular).

    Tony Travis <ajt at>  | Dr. A.J.Travis
                                      | Rowett Research Institute,
                                      | Greenburn Road, Bucksburn, Aberdeen,
                                      | AB2 9SB. UK. tel 0224-712751

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Collagen purification

Abdullah Shaito aas10 at
Thu Jun 25 07:52:06 EST 1998

I am in great need for a method to purify collagen type I and III from rat
hearts by pepsin digestion folowed by differential precipitatin.Anyone who
knows this method please helpas I am getting very low recovery

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Help! I have a parasite

Omar O. Barriga oobarrig at
Fri Feb 28 18:31:31 EST 1997

In article <01bc250f$36ebee20$3dd165cc at steve-wendy> "Steve + Wendy" <swkemp at> writes:
>From: "Steve + Wendy" <swkemp at>
>Newsgroups: bionet.parasitology
>Subject: Help! I have a parasite
>Date: 28 Feb 1997 00:32:35 GMT
>Lines: 10
>Message-ID: <01bc250f$36ebee20$3dd165cc at steve-wendy>
>X-Newsreader: Microsoft Internet News 4.70.1155
>Xref: bionet.parasitology:2124

>Does anyone out there have any information on this parasite :

>My wife has been sick for several months and her doctor found this
>parasite. Her doctor first prescribed Tetracyline and it did not go away.
>She is now on Diodoquin 650mg 3/d - but we are not sure if it is killing
>the thing or not.

>If anyone has any information it would be very much appreciated.

Steve + Wendy:

	Dientamoeba fragilis is an intestinal protozan of humans to
which most specialists do no assign any pathogenic power. That is,it does
not cause disease. I am sure that somebody will come up with an anecdotal
case in which D. fragilis caused some obscure symptoms in some obscure country
in 1826 or about. The fact is, D. fragilis is NOT a cause of disease in >99%
of the cases.  Yoy may do better looking for another case for your wife's
	Good luck,
				Omar O. Barriga

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text:
Hydroponics Web Page

Stan plantone at iquest.net
Sun Feb 26 14:05:22 EST 1995

In article <3iolfj$dkd at steel.interlog.com>, cbriggs at interlog.com (Cullan
Briggs) says:
   >There's a new Hydroponics web page at http://www.io.org/~global

fwiw, my home page "Plantasia On-line" can be found at URL:

   it is under construction, and will encompass many different gardening
   issues.  planning some really neat things, including a constantly
   updating live picture of my indoor garden!

Plantasia Garden Company's on-line catalog can be found at URL:

   it is also under construction, and is due for a drastic format change
   in the next several months, but you can start poking around now.

HELP, HELP, HELP... any comments, suggestions, or contributions you would
like to make to any of my pages would be happily accepted.  i am pressed
for net-time as it is, so if anyone is interested in helping maintain
part of the Plantasia OnLine web page, please give me a holler via email.

i especially need contributions and current information on ORGANIC/SOIL
gardening, FLOWER gardening, HYDROPONIC/OUTDOOR gardening, and HOUSEPLANT
gardening.  the bulk of my personal knowledge and experience is in indoor
gardening under lights (vegetables and herbs), indoor hobby hydroponics,
and outdoor container gardeing.

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text:
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BARRETT, MICHAEL, physician and teacher; b. 16 May 1816, in London, England, son of Michael Barrett and Frances Scott; m. Ellen McCallum, and they had four sons and two daughters; d. 26 Feb. 1887 in Toronto, Ont.

Michael Barrett received the greater part of his early education at Caen, France. In 1833 his father, an English barrister, determined to emigrate and took the family to Upper Canada. Michael lived for a time at Penetanguishene serving as a sailor and engaging in fishing and trading activities on Georgian Bay. Later he taught school at Newmarket, where he turned out on the loyalist side during the rebellion of 1837. About this time his father moved to Natchez, Miss., where Michael later joined him.

About 1843 Barrett returned to Canada West and studied law in Toronto for two years. In 1845 he was appointed second English master at Upper Canada College and assistant master of the college boarding-house. Later he became first English master, and also taught French and geography, but eventually devoted his teaching mainly to physiology, chemistry, and anatomy. His active connection with the college lasted for 35 years. In 1846 he entered King’s College, from which he received a ba in 1849 (he received an ma from the University of Toronto in 1853), and where he also studied medicine. In 1852 he was licensed by the provincial medical board, and in 1855 he was awarded the honorary degree of md from Victoria College.

In 1852 Barrett joined the Toronto School of Medicine, then headed by John Rolph*, and lectured in chemistry and medical jurisprudence. In 1854 the school became affiliated with Victoria College in Cobourg as the medical department of the latter, and Barrett became one of its five professors. He became a member of the senate of the University of Toronto as a representative of the Toronto School of Medicine in 1855 and served in that capacity for some six years. In 1856, after a disagreement between Rolph and his staff, all of the latter, including Barrett, broke with Rolph and set themselves up as an independent proprietary school, taking with them the name, the Toronto School of Medicine, which affiliated with the University of Toronto. At the university Barrett also served as an examiner in medicine and arts in the late 1850s and early 1860s as well as examiner in physiology and comparative anatomy for about five years following 1862. He continued as a professor in the medical school until his death, serving as lecturer in physiology after Dr James Bovell*’s retirement in 1870. He also lectured in this subject at the Ontario Veterinary College in Toronto from the 1860s until his death.

In the last years of his life Barrett played an important part in the establishment of the Ontario Medical College for Women. At a time when women were being denied admission to existing medical schools, Augusta Stowe* Gullen, who would be the first woman to secure an md in Canada, appealed to Barrett and other medical men for assistance. Barrett presided over a public meeting which endorsed plans for a women’s medical school, and he also delivered the main address at the opening of the college in Toronto on 1 Oct. 1883. He was appointed dean and taught at the college until his death.

G. M. Craig

Academy of Medicine (Toronto), William Thomas Aikins papers. “Michael Barrett, M.A., M.D.,” Canadian Practitioner (Toronto), 12 (1887): 94–95. Globe, 28 Feb. 1887. Toronto Daily Mail, 28 Feb. 1887. W. P. Bull, From medicine man to medical man: a record of a century and a half of progress in health and sanitation as exemplified by developments in Peel (Toronto, 1934). W. G. Cosbie, The Toronto General Hospital, 1819–1965: a chronicle (Toronto, 1975). Augusta Stowe Gullen, A brief history of the Ontario Medical College for Women (n. p., 1906).

General Bibliography

Cite This Article

G. M. Craig, “BARRETT, MICHAEL,” in Dictionary of Canadian Biography, vol. 11, University of Toronto/Université Laval, 2003–, accessed July 3, 2015, http://www.biographi.ca/en/bio/barrett_michael_11E.html.

The citation above shows the format for footnotes and endnotes according to the Chicago manual of style (16th edition). Information to be used in other citation formats:

Permalink: http://www.biographi.ca/en/bio/barrett_michael_11E.html
Author of Article: G. M. Craig
Title of Article: BARRETT, MICHAEL
Publication Name: Dictionary of Canadian Biography, vol. 11
Publisher: University of Toronto/Université Laval
Year of publication: 1982
Year of revision: 1982
Access Date: July 3, 2015


text:
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Original title:  Photograph Judge Maguire, Montreal, QC, 1868 William Notman (1826-1891) 1868, 19th century Silver salts on paper mounted on paper - Albumen process 8.5 x 5.6 cm Purchase from Associated Screen News Ltd. I-30759.1 © McCord Museum Keywords:  male (26812) , Photograph (77678) , portrait (53878)

Source: Link

MAGUIRE, JOHN, lawyer, judge of the Superior Court; b. April 1810 at Maguire’s Bridge in Fermanagh County, Ireland, son of Matthew Maguire and Catherine O’Hara; d. 5 July 1880 at Quebec.

John Maguire arrived in Canada in 1823 with his parents. He attended the Petit Séminaire of Quebec and completed his classical education there. He then received legal training in the office of William Power*, and on 20 Sept. 1834 became a member of the bar.

During the 1837 insurrection John Maguire marched under the standard of the Patriotes. He then rallied to the party of Louis-Hippolyte La Fontaine* and offered himself as a candidate on the Liberal-Conservative ticket for the city of Quebec, but was defeated. From then on he turned his talents to municipal politics. Maguire had been a member of the city council for the district of Champlain since 1846 and he occupied this post until 1854. In 1852 he also became inspector and superintendent of police for the city of Quebec. The following year, the English Protestants of Quebec accused him of negligence in carrying out his duty at the time of the riot caused by Alessandro Gavazzi*, a fanatical, anti-Catholic Italian who had come to Quebec to give lectures against “papism” [see Charles Wilson. An inquiry conducted by two Protestant justices of the peace cleared Maguire of all blame. Still in the setting of municipal administration, he was active on the aqueduct committee, where he exerted all his influence to provide Quebec City with the water services it needed.

In 1852 Maguire was appointed judge of the Court of Sessions of the Peace for the district of Quebec. Sixteen years later he became judge of the Superior Court for the district of Bonaventure, and, from 1 Sept. 1873, for the district of Rimouski. In 1877, with two of his colleagues, Judges Thomas McCord* and Louis-Napoléon Casault*, he had the courage to deliver a judgement condemning the Catholic priests of Bonaventure County, who during the previous electoral campaign had supported the Conservative candidate by using their spiritual authority. As Judge Maguire refused to retract, he incurred the wrath of Bishop Jean-Pierre-François Laforce* Langevin, and the bishop excommunicated him. This sentence was lifted by Bishop George Conroy in the autumn of 1877.

At his death, on 5 July 1880, he left his wife, Frances Agnes Horan, sister of Bishop Edward John Horan, the first principal of the école Normale Laval, and nine of his 14 children.

Béatrice Chassé

Rapport des commissaires nommés pour faire une enquête sur la conduite des autorités de police lors de l’émeute de l’église Chalmers, le 6 juin 1853, avec les minutes des procédés et des témoignages rendus devant la dite commission (Québec, 1854). Journal de Québec, 25 oct. 1853; 6 juill., 9 juill. 1880. Morning Chronicle (Quebec), 6 July 1880. Quebec Mercury, 8 July 1880. F.-J. Audet, “Commissions d’avocats de la province de Québec, 1765 à 1849,” BRH, XXXIX (1933), 587. P.-G. Roy, Les juges de la province de Québec, 335. Robert [Philippe] Sylvain, “Séjour mouvementé d’un révolutionnaire italien à Toronto et à Québec,” RHAF, XIII (1959–60), 183–229.

General Bibliography

Cite This Article

Béatrice Chassé, “MAGUIRE, JOHN,” in Dictionary of Canadian Biography, vol. 10, University of Toronto/Université Laval, 2003–, accessed July 3, 2015, http://www.biographi.ca/en/bio/maguire_john_10E.html.

The citation above shows the format for footnotes and endnotes according to the Chicago manual of style (16th edition). Information to be used in other citation formats:

Permalink: http://www.biographi.ca/en/bio/maguire_john_10E.html
Author of Article: Béatrice Chassé
Title of Article: MAGUIRE, JOHN
Publication Name: Dictionary of Canadian Biography, vol. 10
Publisher: University of Toronto/Université Laval
Year of publication: 1972
Year of revision: 1972
Access Date: July 3, 2015


text:
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THOMPSON, JOHN SPARROW, editor, teacher, and writer; b. 1795 at Waterford (Republic of Ireland); m. 24 March 1829, in Halifax, N.S., Charlotte Pottinger, and they had seven children, two of whom seem to have died in infancy; d. 21 Oct. 1867 at Halifax.

John Sparrow Thompson’s parents are almost unknown. His father died before Thompson was 24 and his mother, Mary (Sparrow?) Thompson, in 1832. Both were Methodists, reflecting, no doubt, John Wesley’s mission to Waterford, 1747–53. About 1818 Thompson left Waterford for London. His life there may not have been altogether satisfactory; as early as 1819 his mother was writing that work could apparently be found in America. He may have been a shoemaker but does not seem to have had ambitions in a trade. He liked writing and became proficient at it. A friend wrote to him in 1826: “. . . what you feel you write in good style but you are deficient in the language of strong emotion, perhaps because you [think] . . . such language would be bombast. . . .” By this time Thompson had made up his mind. After a visit to Waterford, he sailed from England early in 1827 in the Osprey for Halifax.

In 1828 he started a private school. Halifax’s score of private schools often provided a thin enough living for their instructors. Thompson had some real talent for teaching, having knowledge of mathematics and astronomy, and being well read in English literature and history. He was also an excellent shorthand writer, a subject his school taught. Advertisements for his school appear in the Novascotian in 1835–36 and 1844, and in the Royal Gazette in 1857. In the early 1850s he was a Halifax school commissioner, along with Alexander Forrester.

Thompson’s teaching career was at times concurrent with, at others consecutive to, his editorial pursuits. In 1830 he became editor of the Halifax Monthly Magazine, a position he held until 1833. His facility in shorthand also brought him substantial extra income. It was Thompson who reported Joseph Howe*’s speech at his libel trial of 1835. Shortly after this Thompson founded the Acadian Telegraph, a newspaper whose first number included the beginning of his “Compendious history of Nova Scotia. . . .” This history, characteristically perhaps, he never finished. The newspaper lasted from August 1836 until February 1838. Thompson then became editor of Howe’s Novascotian while Howe was in England from April to October 1838. In 1839 Thompson became editor of the Pearl, a literary weekly begun in 1837 and purchased by Howe in June 1839, which folded in August 1840. Thompson then became assistant editor, and subsequently editor, of the Novascotian until June 1842.

John Sparrow Thompson was more than a Reformer: he was a radical. He hated class privilege and believed in equal rights and opportunities for all men. On these grounds alone he could never be indifferent to politics; but aside from that, a man’s duty as citizen enjoined his participation. Thompson had a strong sense of independence that scorned sycophancy or even trimming. When he wanted to commit the Pearl unequivocally to the temperance cause, Howe felt compelled to rein him in: “you . . . are about to rush headlong into a warfare with the whole state of society around you, for no sufficient reason, and with the certainty of sacrificing the very means in your hands of promoting the cause you espouse.”

Thompson felt he owed a great deal to Howe. “I have long considered myself in several ways your debtor,” Thompson wrote to him in 1836. And not infrequently Howe’s letters of the later 1830s have remarks on delightful rides with Thompson about Halifax and the province. Howe was as passionate and impulsive personally as was Thompson politically; Thompson had a more controlled and purposeful nature, and a keener, if less ductile, mind. Thompson was also quite unambitious, and, given his penchant for uttering unpalatable truths, was probably unsuited for public life. Nor was he well suited for business. The failure of the Acadian Telegraph might owe something to the times and the number of other papers, but also to Thompson’s unwillingness to sell himself or his paper. A friend wrote him in 1855 about the Athenaeum, with which Thompson was also associated: “. . . there must be business tact and energy. Especially there must be continuous personal application for Advertisements. . . .” These Thompson could not give. He neither sought money nor worried too much about the making of it. In this, at least, he and Howe resembled each other. They remained close friends for life. It was said Howe would rarely write anything of importance that he did not first submit to Thompson’s judgement.

It was owing to Howe that Thompson was appointed queen’s printer in February 1843 during the coalition government. When Howe quarrelled with the governor, Lord Falkland [Lucius Bentinck Cary*], and resigned from the government in December 1843, Thompson’s position was weakened. Falkland charged him with writing partisan reports against the government. These charges Thompson denied, but he resigned in February 1844. He may even have refused to write articles defending Lord Falkland. Resignation was not easy for Thompson; he was now nearing 50, with a family of at least four young children. His brother Joseph wrote consolingly from Ireland: “Yes, better to leave the field honourable in the estimation of friend and partisan rather than wage war (no matter how great the spoils) at the expense of the faintest reproach of conscience. . . .” There indeed spoke the Methodist conscience! How difficult life was for Thompson is suggested by his request to Howe for a loan in August 1846. Howe, in “exile” at Musquodoboit, could only send a blank promissory note with his endorsement; Thompson should “get some friend whose credit is good to put his name under mine. Without that it will be useless to try.”

When Howe returned to office in 1848, in James Boyle Uniacke*’s Reform government, Thompson was reappointed queen’s printer and served until April 1854. He was then replaced by William Annand*, who accepted the office on condition that provision be made for Thompson. Apparently it was not, for Thompson went back to teaching and newspaper work. A Conservative government between 1857 and 1860 prevented any official appointment, but in 1860, on Howe’s return to power, Thompson was made chief official reporter for the assembly, which he remained until the electoral defeat of Howe’s government in 1863. He was also appointed in 1861 chief of the money order department of the Nova Scotia Post Office, a position he held until just before his death.

Thompson had a strong belief in the virtues of local initiative. He was a firm supporter and for many years secretary of the Halifax Mechanics’ Institute, founded in 1831. In later times he loved to gather a few friends to read a paper of his own or to hear another’s. His sense of relevance and his sharp mind showed often to advantage, and he frequently carried a meeting by his cogent good sense. He had a strong dislike of affectation and sentimentality. Associated with Thompson’s Methodism was his belief in temperance. At the opening of the new Temperance Hall in 1850, he described how the Sons of Temperance had met heretofore in the Mason’s Hall: “although courtesy from the proprietors was invariably experienced, bacchanalian strains, frequently mingled with the Temperance Hymn and Address. . . .”

His chief literary work was a labour of love, a collected edition of the poetry of John McPherson* published in 1862. The extensive introduction suggests something of Thompson’s own viewpoint: “Much of a country’s wealth consists in her better minds. To allow the memory of such to disappear, may be considered about as inappropriate and injudicious, as would be the interring of money wealth. . . . Nova Scotia cannot afford to lose such property. . . .” McPherson, too, had had to teach, and his love of meditative peace was “sadly out of keeping with the noise, and roughness, and fagging, and poor pecuniary remuneration. . . .” There spoke Thompson’s experience, too. But he was of tougher metal: an unsparing, yet modest critic whose earnestness was enlivened with an Irish wit, and an Irish accent, which he retained to the end of his life. Irishman that he was, he loved debate and argument. Yet Thompson was a man of charity, unlike many tough-minded reformers. He would burst out against some wrongdoer in high places and afterwards express, as a friend put it, “sympathy for the wicked fool, notwithstanding his offences.” Thompson’s philosophy can be summed up in a sentence from the edition of McPherson: “The mind is the true kingdom of man. . . .” This great gift, together with his integrity, firmness, and spirit, were to be passed on to his more famous son, Sir John Thompson*.

P. B. Waite

[An attractive, indeed haunting, portrait of J. S. Thompson by William Valentine* hangs in the PANS. There is a useful collection of letters including some from Howe and McPherson in the J. S. Thompson papers at PAC (MG 24, C4). There are also a few Thompson letters in the Howe papers (PAC, MG 24, B29). Primary sources should also include the newspapers he edited and the journals to which he contributed. In addition, there are at least two pamphlets: The building and its objects: an essay, read– January 10, 1850, at the first public meeting of the Sons of Temperance in the new Temperance Hall, Poplar Grove, Halifax (Halifax, 1850); The eastern shore: report, to a committee of the Grand Division, S. of T., of Nova Scotia, concerning a temperance and educational mission to the eastern shore of Halifax County (Halifax, 1860). His book on McPherson is: Poems, descriptive and moral . . . (Halifax, 1862).

There is a memoir on Thompson in vol.293, ff.001804-10 of the Sir John Thompson papers (PAC, MG 26, D), written by William A. Hendry of Halifax for Lady Thompson. The information in that memoir was not available to Sir Joseph Andrew Chisholm* for his paper, “John Sparrow Thompson,” N.S. Hist. Soc., Coll., XXVI (1945), 1–31, which has considerable material on Thompson’s newspaper activity. There is also a short article by “Occasional,” in the Acadian Recorder (Halifax), 11 Jan. 1930.  p.b.w.]

General Bibliography

Cite This Article

P. B. Waite, “THOMPSON, JOHN SPARROW,” in Dictionary of Canadian Biography, vol. 9, University of Toronto/Université Laval, 2003–, accessed July 3, 2015, http://www.biographi.ca/en/bio/thompson_john_sparrow_9E.html.

The citation above shows the format for footnotes and endnotes according to the Chicago manual of style (16th edition). Information to be used in other citation formats:

Permalink: http://www.biographi.ca/en/bio/thompson_john_sparrow_9E.html
Author of Article: P. B. Waite
Publication Name: Dictionary of Canadian Biography, vol. 9
Publisher: University of Toronto/Université Laval
Year of publication: 1976
Year of revision: 1976
Access Date: July 3, 2015


text:
Aporepressor --> inactive repressor

a repressor that cannot combine with an operator gene until it has combined with a corepressor (usually a product of a protein pathway); after activation, the repressor arrests production of the proteins controlled by the operator gene; a homeostatic mechanism for regulation of repressible enzyme systems.

Synonym: aporepressor.

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tumour specific antigen

(Science: immunology, oncology) antigen on tumour cells detected by cell-mediated immunity. For virus transformed cells tSTA (unlike t antigen) is found to differ for different individual tumours induced by the same virus. May consist of fragments of T antigens exposed at the cell surface.

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FERC report indicates U.S. added bioenergy capacity in August

By Erin Voegele | September 20, 2013

The Federal Energy Regulatory Commission’s Office of Energy Projects has released its Energy Infrastructure Update report for August, noting that two new biomass power generation units were placed in service during the month with a combined installed capacity of 3 megawatts (MW).

During the first eight months of 2013, the FERC report shows that 46 new biomass power generation units were placed in service. Together, those units have a combined annual production capacity of 171 MW. During the same period of 2012, FERC data shows that 171 biomass power generation units were placed into service, with a combined capacity of 409 MW.

As of the close of August, the FERC estimates the U.S. is home to 15.19 gigawatts (GW) of installed biomass production capacity, accounting for 1.3 percent of total U.S. capacity.

The report does not indicate any additional coal, nuclear, water, wind, geothermal or waste heat power generation units came online in August. However, three natural gas units with a combined capacity of 1,297 MW, 20 solar units with a combined 578 MW capacity and one oil unit with a 1 MW capacity were brought into service.

A full copy of the report can be downloaded here.

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    Leave a Reply

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text:
Document Detail

CDKL5 Mutations as a Cause of Severe Epilepsy in Infancy: Clinical and Electroencephalographic Long-term Course in 4 Patients.
MedLine Citation:
PMID:  22832775     Owner:  NLM     Status:  Publisher
CDKL5 mutations cause severe epilepsy in infancy with subsequent epileptic encephalopathy. As yet, few studies report on long-term observations in patients with CDKL5-related epileptic encephalopathy. In this study, we describe the evolution of the epilepsy phenotype and the electroencephalographic (EEG) features in 4 patients during a maximum observation period of 22 years. All 4 patients had epilepsy starting with focal seizures in the first 3 months of life, evolving to epileptic spasms between the ages of 2 and 6 years and later on to tonic seizures. In 3 patients, epilepsy was resistant to antiepileptic therapy. Although there was no common EEG pattern in all patients, late hypsarrhythmia until the age of 9 years was observed in 2 patients. CDKL5-related epileptic encephalopathies are a group of refractory seizure disorders starting in early infancy. The phenomenon of late hypsarrhythmia may help define a subgroup of patients with severe and adverse outcomes.
Johanna Jähn; Almuth Caliebe; Sarah von Spiczak; Rainer Boor; Irina Stefanova; Ulrich Stephani; Ingo Helbig; Hiltrud Muhle
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-25
Journal Detail:
Title:  Journal of child neurology     Volume:  -     ISSN:  1708-8283     ISO Abbreviation:  -     Publication Date:  2012 Jul
Date Detail:
Created Date:  2012-7-26     Completed Date:  -     Revised Date:  -
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  -
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -
Export Citation:
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MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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Document Detail

Exercise training improves exercise capacity and quality of life in patients with inoperable or residual chronic thromboembolic pulmonary hypertension.
MedLine Citation:
PMID:  22848542     Owner:  NLM     Status:  MEDLINE
BACKGROUND: Aim of this prospective study was to evaluate the effects of exercise training in patients with inoperable or residual chronic thromboembolic pulmonary hypertension (CTEPH).
METHODS: Thirty-five consecutive patients with invasively confirmed inoperable or residual CTEPH (16 women;19 men; mean age 61±15 years, mean pulmonary artery pressure, 63±20 mmHg; primary inoperable n = 33, persisting pulmonary hypertension after pulmonary endarterectomy n = 2) on stable disease-targeted medication received exercise training in-hospital for 3 weeks and continued at home for 15 weeks. Medication remained unchanged during the study period. Efficacy parameters have been evaluated at baseline, after 3 and 15 weeks by blinded-observers. Survival rate has been evaluated in a follow-up period of median 36.4 months (interquartile range 26.6-46.6 months).
RESULTS: All patients tolerated exercise training without severe adverse events. Patients significantly improved the mean distance walked in 6 minutes compared to baseline by 61±54 meters after 3 weeks (p<0.001) and by 71±70 meters after 15 weeks (p = 0.001), as well as scores of quality-of-life questionnaire, peak oxygen consumption and maximal workload. NT-proBNP improved significantly after 3 weeks of exercise training (p = 0.046). The 1-year survival rate was 97%, 2-year survival rate was 94% and the 3-year-survival 86% respectively.
CONCLUSION: Training as add-on to medical therapy may be effective in patients with CTEPH to improve work capacity, quality of life and further prognostic relevant parameters and possibly improves the 1-, 2- and 3-year survival rate. Further multicentric randomized controlled studies are needed to confirm these promising results.
Christian Nagel; Felix Prange; Stefan Guth; Jochen Herb; Nicola Ehlken; Christine Fischer; Frank Reichenberger; Stephan Rosenkranz; Hans-Juergen Seyfarth; Eckhard Mayer; Michael Halank; Ekkehard Grünig
Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-07-25
Journal Detail:
Title:  PloS one     Volume:  7     ISSN:  1932-6203     ISO Abbreviation:  PLoS ONE     Publication Date:  2012
Date Detail:
Created Date:  2012-07-31     Completed Date:  2013-04-09     Revised Date:  2013-07-12
Medline Journal Info:
Nlm Unique ID:  101285081     Medline TA:  PLoS One     Country:  United States
Other Details:
Languages:  eng     Pagination:  e41603     Citation Subset:  IM
Centre for Pulmonary Hypertension, Thoraxclinic at University Hospital Heidelberg, Heidelberg, Germany.
Data Bank Information
Bank Name/Acc. No.:
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MeSH Terms
Aged, 80 and over
Chronic Disease
Exercise Therapy / adverse effects,  methods*
Follow-Up Studies
Hypertension, Pulmonary / complications,  physiopathology*,  surgery,  therapy*
Middle Aged
Pulmonary Embolism / complications*
Quality of Life*
Survival Analysis
Young Adult

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Treatment of biceps tendon lesions in the setting of rotator cuff tears: prospective cohort study of tenotomy versus tenodesis.
MedLine Citation:
PMID:  20551285     Owner:  NLM     Status:  MEDLINE
BACKGROUND: During rotator cuff repair, biceps tendon lesions are frequently encountered. However, there is still controversy about optimal treatment for these lesions.
PURPOSE: To compare the results of tenotomy and suture anchor tenodesis prospectively.
STUDY DESIGN: Cohort study; Level of evidence, 2.
METHODS: From January 2006 to June 2007, 90 patients (age, >55 years) with a rotator cuff tear and biceps tendon lesion (tear more than 30%, subluxation or dislocation, or degenerative superior labrum anterior to posterior lesion type II) were evaluated prospectively. The first 45 patients treated consecutively underwent biceps tenodesis, and the next 45 underwent biceps tenotomy. Postoperatively, patient evaluations were conducted with a focus on (1) "Popeye" deformity, (2) arm cramping pain, and (3) elbow flexion powers (measured with a hand dynamometer). Overall shoulder function was assessed with the American Shoulder and Elbow Surgeons (ASES) score and the Constant score.
RESULTS: At final follow-up, 43 in the tenodesis and 41 in the tenotomy groups were available for evaluation. There was no difference between groups in demographic data such as age, sex, dominant arm, and the time from symptom to surgery and in preoperative ASES score, Constant score, and rotator cuff tear size. A Popeye deformity occurred in 4 (9%) in the tenodesis group and in 11 (27%) in the tenotomy group (P = .0360). Mild cramping pain was observed in 2 in the tenodesis group and 4 in the tenotomy group (P = .4274). Mean elbow flexor power ratio (vs the contralateral side) showed no difference between the 2 groups, with mean values of 0.92 +/- 0.15 (tenodesis) and 0.94 +/- 0.19 (tenotomy) (P = .7475). The ASES and Constant scores were improved from 38.9 +/- 14.2 and 52.1 +/- 21.3 to 84.7 +/- 13.6 and 82.9 +/- 13.5 in the tenodesis group (P < .0001) and from 35.2 +/- 10.5 and 48.1 +/- 21.3 to 79.6 +/- 15.8 and 78.3 +/- 14.1 in the tenotomy group (P < .0001), respectively.
CONCLUSION: Suture anchor tenodesis of the long head of the biceps tendon appears to lead to less Popeye deformity than tenotomy. No other clinical variables showed a difference between the 2 modalities.
Kyoung Hwan Koh; Jin Hwan Ahn; Sang Min Kim; Jae Chul Yoo
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2010-06-15
Journal Detail:
Title:  The American journal of sports medicine     Volume:  38     ISSN:  1552-3365     ISO Abbreviation:  Am J Sports Med     Publication Date:  2010 Aug
Date Detail:
Created Date:  2010-08-02     Completed Date:  2010-12-03     Revised Date:  -
Medline Journal Info:
Nlm Unique ID:  7609541     Medline TA:  Am J Sports Med     Country:  United States
Other Details:
Languages:  eng     Pagination:  1584-90     Citation Subset:  IM
Department of Orthopaedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-Dong, Kangnam-Gu, Seoul, Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Cohort Studies
Humerus / surgery
Middle Aged
Muscle, Skeletal / surgery*
Outcome Assessment (Health Care)
Prospective Studies
Rotator Cuff / injuries*,  surgery
Shoulder Joint / surgery
Tendon Injuries / surgery*
Comment In:
Z Orthop Unfall. 2010 Sep;148(5):508   [PMID:  20931697 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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Document Detail

On the relationships between disgust and morality: A critical review.
MedLine Citation:
PMID:  23628537     Owner:  NLM     Status:  In-Data-Review
Background: Disgust is, at its core, an emotion that responds to cues of parasites and infection, likely to be evolved to protect human organism from the risk of disease. Interestingly, a growing body of research implicates disgust as an emotion central to human morality. The fact that disgust is associated with appraisals of moral transgressions and that this emotion influences moral judgments implies a remarkable puzzle: Why does an emotion that originally functions in the domain of infectious entities become such a good candidate to play the role of a moral arbiter? The aim of the present review is to clarify the nature of the relationship between disgust and morality. Method: First, we examine the relevant features of disgust in order to explore whether the phenomenology of disgust favors its implementation as a defensive mechanism against offensive social entities. Second, we critically review the most striking findings about the effects of disgust on moral judgments. Results: The revisited analysis of the literature strongly suggests a bidirectional causal link between disgust and moral cognition. Conclusions: We propose that the particular phenomenology of disgust (which involves a sense of offensiveness and rejection) favored the co-adaptation of this emotion to the moral domain.
Antonio Olivera La Rosa; Jaume Roselló Mir
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Publication Detail:
Type:  Journal Article
Journal Detail:
Title:  Psicothema     Volume:  25     ISSN:  1886-144X     ISO Abbreviation:  Psicothema     Publication Date:  2013 May
Date Detail:
Created Date:  2013-04-30     Completed Date:  -     Revised Date:  -
Medline Journal Info:
Nlm Unique ID:  101189384     Medline TA:  Psicothema     Country:  Spain
Other Details:
Languages:  eng     Pagination:  222-6     Citation Subset:  IM
Universitat de les Illes Balears.
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MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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Ask Professor Sarah Bellum

Professor Sarah Bellum answers your questions on navigating the often-uncharted waters of early career development. Professor Bellum is communicated by Patricia L. Clark, founder of the Early Careers Committee and a member of Council. Do you have a question for Professor Bellum? Send it to Your privacy is assured!

How can I improve the chance of my abstract being selected for a platform presentation?

Q: As an active member of the Biophysical Society, I have enjoyed presenting posters at the Annual Meeting over the years. This year, however, I was very keen to contribute to a platform session and requested that my abstract be considered for a talk. Indeed, I also volunteered my services for the arduous task of chairing a platform session. But yet again, my abstract was programmed as a poster rather than a platform talk. Is my research not of sufficient interest to the biophysical community? I regularly see some of the same faces providing talks at the Annual Meeting. Why are they selected and others not considered?

A: Competition for platform session talks at the Biophysical Society Annual Meeting is steep: for the 2012 Meeting, over 3,700 abstracts were submitted. Roughly a third of these submissions requested a platform presentation, which amounted to three times the total number of speaking slots available (~400). But there are several things that you can do to improve your chances of having your abstract selected for an oral platform presentation. Here, I have focused specifically on the Biophysical Society and its Annual Meeting, but I suggest you also consult other sources for more general advice for packaging and promoting your research—a quick search of The Chronicle of Higher Education web site using the key words “research networking publicize” returned 196 articles in their “Advice” section alone!

First, make sure that you select an abstract category that is a good fit for your research. Will the members of this community find your results interesting? The answer can help decide between two categories that might initially appear to be equally good fits for your research. For example, if you characterized the unique folding properties of a novel protein structure using fairly standard fluorescence techniques, your results will likely be of more interest to the protein folding community than the community of biophysicists who develop novel fluorescence techniques. And of course, write your abstract in a way that clearly demonstrates and objectively supports a significant contribution to the body of knowledge in your chosen category.

Second, pick a popular abstract category. The Society is committed to sponsoring an Annual Meeting that reflects the diverse interests of its membership, but given that there are many more requests for platform talks than slots available, platform sessions are typically programmed for abstract categories that receive at least 40 submissions. You can use the past Meeting programs [1] to figure out which categories tend to be popular each year. However, 40+ submissions is a guideline, not a rule: it varies depending on the number of total abstracts submitted, and abstracts from “small” categories are often combined to create additional platform sessions in areas that do not receive enough submissions to be considered independently. But do not despair if your research does not fall within a pre-existing popular abstract category: see below for alternative suggestions for how to land a speaking slot.

Third, make sure you and your research are on the radar of those selecting platform speakers. After the abstract submission deadline, each member of the Program Committee and the Council of the Biophysical Society will be assigned to one or more specific abstract categories. These members of the Society are responsible for deciding which abstracts are selected for platform talks versus poster sessions. The most popular categories receive hundreds of submissions each year, so it is important to make sure that your abstract stands out from the crowd. Over the long term, the best way to do this is to publish high-quality articles in high-quality journals. But if you do not yet have a publication record in your abstract area, or if your publications have not yet produced a platform invitation, you can further increase the visibility of your abstract by getting the members of Council and the Program Committee in your area and related ones to know you and your research, as these are the people most likely to select speakers for platform sessions in your area.

A great way to get to know the members of Council and the Program Committee is to be an active participant in the leadership of the Society, either by becoming a member of a Society committee or participating in subgroups. Many current and past members of committees and Council first got involved with the governance of the Society because they were interested in participating in the subgroup governance or annual meeting programs developed by the Society committees. In addition to putting you in closer contact with the people who decide which abstracts are selected for platform sessions, joining a committee or subgroup is a great way to give back to the broader biophysical community, and support the efforts of the Society.

Networking matters because we are all very busy, and abstract programming is yet one more task added to an already too-long to-do list. Council and the Program Committee want to put together the strongest possible Annual Meeting program, but they do not have the time to decipher impenetrable abstracts or do the background reading required to understand the significance of a specific argument outside their own research sub-field. Some also worry whether people who they do not know will give a strong oral presentation. One unfortunate consequence of these concerns is that it becomes all too easy to select speakers who have spoken before. So, make it easy for those in charge to select your abstract: write clearly, and become known as a good speaker. Even if you are currently struggling to secure speaking slots, you can use other mechanisms to increase your visibility in your research area: Ask thoughtful questions after other talks, and introduce yourself to session organizers, members of Council, and Program Committee members. Briefly mention what you work on and why it is fascinating. It would not hurt to point out that you are a dedicated Meeting attendee and would be thrilled to give a talk at a future Meeting.

Fourth, consider other ways to secure a speaking slot at the meeting. Abstract categories – like research areas – are not static, and the Annual Meeting has mechanisms in place to help members organize around new and emerging areas. One of these is the annual New & Notable Symposium, where members can nominate themselves or others for consideration for a late-breaking talk at the Meeting. As a member, you should receive an email from the Society asking for New & Notable nominations in November. Another option is to submit a proposal to chair a member-organized platform session. This requires arranging in advance (typically by September) with seven other abstract submitters to participate in your proposed platform session, and describing how your session topic is not addressed by existing platform sessions. Proposing a member-organized session requires more work from you than submitting an abstract to an existing category, but it can be a great way to help a community focus around an emerging technique or finding. Complete details for developing your proposal are available on the Annual Meeting web site [2]. Finally, please do consider the possibility that, particularly if your research focus has shifted over time, you might now have moved into a field that, while fascinating in its own right, is not well-represented within the Biophysical Society. The Society has an obligation to host an Annual Meeting that is representative of its membership, and if your area represents <1% of the membership, it is not likely that your area will be featured at the Meeting. In this scenario, you can either try to attract more members of your field to participate in the Biophysical Society and its Annual Meeting—perhaps assembling a member-organized session, described above—or start a subgroup that will attract more researchers in your field to the Meeting, thus increasing membership and posters in the field.

June 2012 Table of Contents


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Therapeutic effect of near infrared (NIR) light on Parkinson's disease models.

13:19 EDT 3rd July 2015 | BioPortfolio

Summary of "Therapeutic effect of near infrared (NIR) light on Parkinson's disease models."

Parkinson's disease (PD) is a neurodegenerative disorder that affects large numbers of people, particularly those of a more advanced age. Mitochondrial dysfunction plays a central role in PD, especially in the electron transport chain. This mitochondrial role allows the use of inhibitors of complex I and IV in PD models, and enhancers of complex IV activity, such as NIR light, to be used as possible therapy. PD models fall into two main categories; cell cultures and animal models. In cell cultures, primary neurons, mutant neuroblastoma cells, and cell cybrids have been studied in conjunction with NIR light. Primary neurons show protection or recovery of function and morphology by NIR light after toxic insult. Neuroblastoma cells, with a gene for mutant alpha-synuclein, show similar results. Cell cybrids, containing mtDNA from PD patients, show restoration of mitochondrial transport and complex I and IV assembly. Animal models include toxin-insulted mice, and alpha-synuclein transgenic mice. Functional recovery of the animals, chemical and histological evidence, and delayed disease progression show the potential of NIR light in treating Parkinson's disease.

Department of Neurology, Medical College of Wisconsin, 8701 W. Watertown Plank Rd, Milwaukee, WI, 53226, USA.

Journal Details

This article was published in the following journal.

Name: Frontiers in bioscience (Elite edition)
ISSN: 1945-0508
Pages: 818-23

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The primary objective of the study is to determine the utility of blood plasma infrared spectroscopy (biospectroscopy) in distinguishing subjects with idiopathic Parkinson's disease from h...

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The Effect of Exercise on Individuals With Parkinson's Disease

The goal of this trial is to compare the effect of two different exercise programs on neuro-physiological, motor, functional, and quality-of-life issues in individuals with Parkinson's dis...

Medical and Biotech [MESH] Definitions

Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.

That portion of the electromagnetic spectrum usually sensed as heat. Infrared wavelengths are longer than those of visible light, extending into the microwave frequencies. They are used therapeutically as heat, and also to warm food in restaurants.

Techniques using energy such as radio frequency, infrared light, laser light, visible light, or acoustic energy to transfer information without the use of wires, over both short and long distances.

Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.

A condition caused by the neurotoxin MPTP which causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (PARKINSON DISEASE, SECONDARY). MPTP toxicity is also used as an animal model for the study of PARKINSON DISEASE. (Adams et al., Principles of Neurology, 6th ed, p1072; Neurology 1986 Feb;36(2):250-8)

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News | June 4, 2014

Swiss World Cargo: Collaborating To Make A Difference

Contact The Supplier

Active Container damage is a very sensitive topic within Swiss WorldCargo. Until the beginning of 2013, the damage ratio (damaged units in % of total volume) steadily increased over the years. These damages did not affect the quality of the container performance, as the damage usually occurred outside of the container. The costs however were rising to an unacceptable level.

That is why Swiss WorldCargo initiated a Kaizen (Process Improvement) Workshop in order to determine where, when and why these damages happen and to implement corrective actions to prevent them in the future. The workshop took place in Chicago, where 13 participants joined from all over the world. Besides Swiss World Cargo, members from Envirotainer and Lufthansa Cargo also participated.

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Cytovance Biologics Inc. Awarded Biopharmaceutical Development and Manufacturing Contract by Fountain BioPharma, Inc.

10/31/2012 11:06:49 AM

OKLAHOMA CITY, OK--(Marketwire - October 31, 2012) -

Cytovance Biologics, Inc. and Fountain BioPharma, Inc. jointly announce the execution of a Biopharmaceutical Development and Manufacturing collaboration for FB301, a novel monoclonal antibody (mAb) being developed for the treatment of allergy as a lead indication.

Under the scope of this agreement, Cytovance will spearhead the cell line generation, cell culture process optimization, recovery and purification development, cGMP manufacturing as well as technical and regulatory support to facilitate Fountain's clinical program. FB301 will be developed at Cytovance Biologics' state-of-art process development and analytical laboratories and manufactured at its 44,000 sq. ft. production facility that was custom-designed for multi-product cGMP manufacturing and meets U.S. and EU regulatory standards.

"Cytovance is excited that Fountain has chosen us to support this innovative treatment for Allergy," said Darren Head, President and Chief Executive Officer of Cytovance Biologics. "Our experienced staff and state-of-the-art facilities are prepared to deliver the highest quality of development and manufacturing services for successful completion of this clinical milestone for FB301."

"We have successfully completed several development and manufacturing service agreements with Asian clients in the past two years and are actively expanding our services to the Asian Pacific region, led by Dr. Jeffrey Su, our Chief Scientific Officer," added Mr. Head.

"The FB301 antibody is Fountain's flagship product, which represents a new, innovative medicine to treat a vast array of IgE-mediated allergic diseases; FB301 is licensed from Academia Sinica, the internationally renowned and most prestigious research institute in Taiwan," said Dr. Willie Lin, President of Fountain BioPharma, Inc. "We are pleased to collaborate with Cytovance for advancing the development of Fountain's FB301 product, and look forward to a prosperous relationship between the two companies."

About Cytovance® Biologics

Cytovance® Biologics is a biopharmaceutical contract manufacturing company specializing in the production of therapeutic proteins and antibodies from both mammalian cell culture and microbial fermentation. In addition to its cGMP manufacturing services, the company offers process development, cGMP cell banking and support services from its Oklahoma City state-of-the-art facilities. Our customers receive unparalleled services that meet global regulatory standards and facilitate efficient completion of clinical development.

Learn more at www.cytovance.com.

About Fountain BioPharma, Inc.

Fountain BioPharma, Inc. is a biotechnology company focused on the discovery, development and delivery to patients of novel antibody therapeutics for treatment of cancer, autoimmune disorders and allergic diseases. Fountain has built a fully-integrated set of capabilities in antibody-based product development which supports its innovative pipelines of clinical stage product candidates. Fountain' proprietary research is based on three core technology platforms, which include: (1) healthy and disease-specific fully human antibody libraries; (2) protein-, cell- and tissue-based antibody screening, and (3) top IgE and anti-IgE R&D in the world. The company has multiple research and development collaborations with prestigious research institutes in Taiwan including Academia Sinica, National Health Research Institute and National Taiwan University Hospital.

Learn more at www.fountainmab.com.

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Jodie Gutkowski
Marketing Communications Manager
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Ethicon Endo-Surgery, Inc. Extends Research Partnership with $13.5 Million Grant to University of Cincinnati

6/22/2010 7:10:12 AM

LAS VEGAS, June 22 /PRNewswire/ -- Ethicon Endo-Surgery, Inc. (EES) today announced it has renewed its research collaboration agreement with the University of Cincinnati (UC) and its Metabolic Diseases Institute (MDI). The three-year, $13.5M grant extension, is part of the EES Metabolic Applied Research Strategy (MARS), which also includes research from GI Metabolism Laboratory and Weight Center at the Massachusetts General Hospital (MGH). The MARS initiative is aimed at improving the understanding of the physiological changes resulting from bariatric surgery. EES will highlight findings and potential implications of this research from both institutions this week at the annual meeting of the American Society for Metabolic and Bariatric Surgery (ASMBS).

With an estimated 300 million adults worldwide categorized as clinically obese(i), the overarching goal of the MARS initiative is to develop additional, less invasive treatment options and improved outcomes for people with obesity. Current surgical intervention options for patients with obesity have been shown to resolve Type II diabetes in a significant number of patients (78 percent of gastric bypass patients(ii) and 73 percent in banding patients(iii)) and may result in weight loss of 81 percent of their excess weight as early as 12 months after surgery.(iv) However, these techniques have resulted in weight loss that exceeds the amount expected based on reduced caloric intake alone. MARS research is underway to explain this discrepancy.

At UC's MDI, Randy Seeley, Ph.D. is leading efforts aimed at increasing the understanding of why other metabolic procedures, such as vertical sleeve gastrectomy (VSG) and laparoscopic greater curvature plication (LGCP), work. Including this new grant, the EES MARS initiative has invested more than $33M with UC and the GI Metabolism Laboratory and Weight Center at the MGH, where Lee Kaplan, M.D., Ph.D., is leading research into understanding the mechanisms of action in Roux-en-Y gastric bypass surgery.

This past Sunday, Seeley presented data and findings, which stem from the MARS initiative, on the mechanism of action of VSG during an educational course for physicians attending ASMBS, illustrating a greater understanding of how the procedure impacts physiological factors contributing to body weight regulation and resolution of co-morbid conditions. Also at ASMBS, EES will highlight research from the GI Metabolism Laboratory and Weight Center at the MGH during a presentation and educational event.

"If we can truly understand the physiology behind how bypass surgery works, we can leverage this knowledge to create less invasive devices and procedures, creating a variety of weight loss options," said Dr. Kaplan, director of the GI Metabolism Laboratory and Weight Center at the MGH. "Finding ways to 'bypass the bypass' is a very exciting area of research that we hope will deliver options that are well suited for the large percentage of obesity sufferers who aren't currently receiving treatment."

Preliminary MARS results have been, and will continue to be, shared this year at several diverse clinical and scientific conferences. Recently, data were presented at Digestive Disease Week (DDW) 2010 by researchers from the GI Metabolism Laboratory and Weight Center at the MGH that demonstrated Roux-en-Y Gastric Bypass (RYGB) accelerated an increase in circulating levels of certain bile acids following meals. Because these bile acids have previously been shown to activate thermogenesis (the production of heat) in muscle and brown adipose tissue, the researchers concluded that this accelerated response from patients who have undergone RYGB may be linked to the increased energy expenditure. This conclusion provides valuable insight into how RYGB works and may lead researchers to novel treatments that are less invasive but still deliver both weight loss and metabolic improvements.

"Ethicon Endo-Surgery is committed to collaborating with clinicians to develop new, comprehensive bariatric solutions while also ensuring that people with obesity have access to current treatment options that can help them achieve sustained weight loss and reduce co-morbidities," said Karen Licitra, group Chairperson, Ethicon Endo-Surgery. "Due to the incredible research being performed at institutions such as UC and MGH, the MARS program is yielding very exciting results that are changing our understanding of how bariatric surgery works. We strongly believe continued efforts in this area will dramatically improve our collective ability to treat obesity and metabolic diseases."

MARS Research at ASMBS and American Diabetes Association Annual Meetings

Dr. Kaplan will discuss the MARS initiative and potential implications for bariatric surgery at the EES booth (#403) on Thursday, June 24, at 9:45 a.m. Dr. Kaplan will also present to ASMBS attendees during the evening of Tuesday, June 22, at an EES-sponsored event that will feature a panel of experts discussing a variety of important topics, including metabolics, new technology and revision surgery.

New ways to prevent and treat obesity and diabetes will also be a central focus at the upcoming American Diabetes Association annual meeting June 25-29 in Orlando, Florida. Dr. Kaplan will discuss data from the MARS initiative and advances in metabolic surgery during a continuing medical education (CME) symposium on biological and mechanical treatments of diabetes, sponsored in part by an educational grant from EES.

About Ethicon Endo-Surgery

Ethicon Endo-Surgery develops and markets advanced medical devices for minimally invasive and open surgical procedures, focusing on procedure-enabling devices for the interventional diagnosis and treatment of conditions in general and bariatric surgery, as well as gastrointestinal health, gynecology and surgical oncology. More information can be found at www.ethiconendo.com.

(i) World Health Organization. Global Strategy on Diet, Physical Activity and Health. 2003.

(ii) Buchwald, H. et al. Weight and Type 2 Diabetes after Bariatric Surgery: Systematic Review and Meta-analysis. American Journal of Medicine. 2009; 122(3): 205-206.

(iii) Dixon, JB et al. Adjustable Gastric Banding and Conventional Therapy for Type 2 Diabetes. Journal of the American Medical Association. 2008; 299(3): 316-323.

(iv) Wittgrove, AC, et al. Laparoscopic Gastric Bypass, Roux-en-Y: Technique and Results in 75 Patients With 3-30 Months Follow-up. Obesity Surgery 1996: 6, 500-504

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Pharma: Clinic Roundup

Thursday, May 2, 2013
• Almirall SA, of Barcelona, Spain, and Forest Laboratories Inc., of New York, reported positive topline results from AUGMENT COPD, the second six-month pivotal Phase III trial evaluating the efficacy and safety of investigational fixed-dose combinations of aclidinium bromide (LAMA) and formoterol fumarate (LABA), delivered in the Pressair (Genuairn outside the U.S.) inhaler.

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Tihomir Topuzovski

Doctoral Researcher

School of Geography, Earth and Environmental Sciences

Tihomir Topuzovski

Contact details

School of Geography, Earth and Environmental Sciences
University of Birmingham
B15 2TT

Supervisors: Dr Stefan Buzarovski, Dr Dominique Moran (and Dr Mark Bassin in the first year of research)

The purpose of this thesis is to investigate the ‘instrumental territorialisation’ (the concept based on Foucauldian and Deleuzian premise) of the Western Balkans, and the manner in which this process is enmeshed within wider political and cultural dynamics. Through this, I explore the relevance of theoretical concepts such as panopticon and heterotopia within the context of the region, while interrogating the different ways in which the rearrangement of the state and regional boundaries have been implicated in the rise of new identities and artistic practices.

Tihomir Topuzovski has three degrees (two BAs in Philosophy and Art, and an MA in Art), and has received various academic achievement awards and research grants. He has also published a number of papers and participated in individual group exhibitions. Tihomir's PhD is funded by a School studentship and an Overseas College Scholarship.

Research interests

Political philosophy, Aesthetics, The territorial aspects of post communist transitions

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