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Monthly Archives: April 2014

Researchers from the Institute of Neuroscience at the Universitat Autònoma de Barcelona claim to have reversed memory loss in Alzheimers disease mouse models, using gene therapy.

The team of researchers discovered the cellular mechanism involved in memory consolidation and were able to inject the hippocampus with a gene which causes the production of a protein blocked in patients with Alzheimer’s, Crtc1 (CREB regulated transcription coactivator-1). Once restored, the protein allows free passage to signals needed to activate the genes involved in long-term memory functioning.

When the Crtc1 protein is altered, the genes responsible for the synapsis or connections between neurons in the hippocampus cannot be activated and the individual cannot perform memory tasks correctly, explained Carlos Saura, head of the research team.

The study authors suggest that a cure for AD lies in developing pharmacological therapies, which can activate the Crtc1 protein thus preventing, slowing down or reverting cognitive changes.

Their research appears on the cover of the 23 April edition of The Journal of Neuroscience.

Source: Journal of Neuroscience

JPND has launched a rapid action call for leading scientists in the field to establish working groups to enhance the use of existing longitudinal cohort studies for neurodegenerative disease research.

Current population and disease-focused cohorts offer a significant opportunity for advancing our understanding of the risks of developing neurodegenerative conditions and the influences on disease progression. Such cohorts also offer the prospect of providing platforms for prevention and intervention studies in the longer term.

As identified in the recently published report of the JPND Action Group on Longitudinal Cohort studies in ND research, a number of methodological challenges remain if such resources are to be fully exploited. The report also identified a number of areas where further thinking is specifically needed to provide the necessary consensus and framework to support future studies of impact for the field. These were:

  • assessing the presymptomatic stages of ND, where new methodological approaches, tools and measures are required.
  • the development of standards to support brain imaging, where guidelines are needed to frame future multimodal imaging approaches and perspectives in molecular imaging.
  • measurement of cognitive, behavioural and functional changes of relevance to ND progression and outcome , where a consensus on the methodologies to be used is needed.
  • data handling, where the emergence of ‘omics’ technologies requires new approaches to data integration and the interrogation and accessibility of big data sets.
  • cohort alignment: in depth work is needed to identify where cohorts can be brought together in selected areas, with concurrent work on how data pooling can realistically be achieved.
  • clinical data linkage: an assessment is needed of how studies with clear clinical linkage might be exploited in prospective studies, such that study harmonisation might be achieved, with the identification of best practice for of data protection, storage and dissemination solutions.
  • the potential for exploiting intervention-studies of potential risk factors where ND is not the primary focus (eg. clinical trials in hypertension, diabetes etc), to ascertain how they could be used to adequately address risk of ND as an outcome.

JPND has decided that these issues can be progressed most effectively through assembling motivated groups of leading experts in the ND field. Accordingly community-led Working Groups are to be supported that can push forward the conceptualization of such topics in order to provide guidelines and/or best practice frameworks of value to the wider research community. Areas to be considered are highlighted above, although other topics that are similar in theme may be proposed.

Funds available and form of support

Up to 450,000 in total will be available to fund Working Groups under this call, with each Working Group able to bid up to 50,000 for support of its activities, which are expected to run for a maximum of 6 months. As the Working Groups will be expected to deliver reports of wide applicability to the field of ND research, only one activity will be funded in any topic area. Funding will cover the costs of meetings and travel required to deliver the Working Groups’ objectives.

Participating JPND countries

This is a transnational call and Working Groups can be comprised of members of any JPND-member country and beyond. However, the lead-coordinator of the Working Group should be based in one of the following countries that are contributing to this call:

  • Denmark, Danish Strategic Research Council
  • France, French National Research Agency
  • Germany, Federal Ministry of Education and Research (pending final approval)
  • Italy, Ministry of Health
  • Luxemburg, National Research Fund
  • The Netherlands, The Netherlands Organisation for Health Research and Development
  • Norway, The Research Council of Norway
  • Sweden, The Swedish Research Council for Health, Working Life and Welfare
  • United Kingdom, Medical Research Council

The proposal submission deadline for the call is 17:00 (GMT+1, Summer Time) on June 16th, 2014

More information on the call is available at:

Media enquiries should be directed to:

Derick Mitchell,, +353 1 2345103

A new line of mice promises to circumvent many of the problems of existing models by recapitulating much of the pathology seen in presymptomatic Alzheimer’s, without overexpressing APP or interrupting other mouse genes.

Over the last two decades, researchers have generated dozens of different mouse models of Alzheimer’s disease. The most commonly used lines carry mutant forms of human Abeta precursor protein (APP), either alone or in combination with human presenilin, tau, or other genes.

Used for both basic research and drug discovery, these animals have provided a wealth of information. However, there have been niggling doubts from the beginning that some of their phenotypes may have little to do with the human disease, and negative clinical trials later reinforced critical debate about the validity of overexpression models.

For example, some models can only be maintained on specific genetic backgrounds, some die young or have surprising phenotypes when crossed with other mouse lines, and in others amyloidosis drifts later in successive generations, suggesting gene expression changes from parents to offspring.

Enter a new line of mice that promises to circumvent many of these problems. Researchers led by Takaomi Saido have engineered APP knock-ins. These animals recapitulate much of the pathology seen in presymptomatic AD, without overexpressing APP or interrupting other mouse genes. How do these knock-ins compare? Click on the link below:

Source: AlzForum

Autopsies have revealed that some individuals develop the cellular changes indicative of Alzheimer’s disease without ever showing clinical symptoms in their lifetime.

Vanderbilt University Medical Center memory researchers have discovered a potential genetic variant in these asymptomatic individuals that may make brains more resilient against Alzheimer’s.

"Most Alzheimer’s research is searching for genes that predict the disease, but we’re taking a different approach. We’re looking for genes that predict who among those with Alzheimer’s pathology will actually show clinical symptoms of the disease," said principal investigator Timothy Hohman, Ph.D., a post-doctoral research fellow in the Center for Human Genetics Research and the Vanderbilt Memory and Alzheimer’s Center.

The article, "Genetic modification of the relationship between phosphorylated tau and neurodegeneration," was published online recently in the journal Alzheimer’s and Dementia. (click to access the Pubmed abstract)

The researchers used a marker of Alzheimer’s disease found in cerebrospinal fluid called phosphorylated tau. In brain cells, tau is a protein that stabilizes the highways of cellular transport in neurons. In Alzheimer’s disease tau forms "tangles" that disrupt cellular messages.

Analyzing a sample of 700 subjects from the Alzheimer’s Disease Neuroimaging Initiative, Hohman and colleagues looked for genetic variants that modify the relationship between phosphorylated tau and lateral ventricle dilationa measure of disease progression visible with magnetic resonance imaging (MRI). One genetic mutation (rs4728029) was found to relate to both ventricle dilation and cognition and is a marker of neuroinflammation.

"This gene marker appears to be related to an inflammatory response in the presence of phosphorylated tau," Hohman said. "It appears that certain individuals with a genetic predisposition toward a ‘bad’ neuroinflammatory response have neurodegeneration. But those with a genetic predisposition toward no inflammatory response, or a reduced one, are able to endure the pathology without marked neurodegeneration."#

Hohman hopes to expand the study to include a larger sample and investigate gene and protein expression using data from a large autopsy study of Alzheimer’s disease.

Source:  Vanderbilt University, USA

Google Glass is being used by people suffering from Parkinsons disease in a groundbreaking experiment to see if the technology can help improve their day-to-day lives.

Newcastle University, UK is trialling new technology to help patients suffering from Parkinson’s disease live more independently by reminding them to swallow, speak up and take their medication.

The Google technology, which is not yet available in Europe, reminds the patients to take their medication, contacts relatives in an emergency and can even prevent debilitating episodes of paralysis  known as freezing.

The system works like a hands-free smartphone, displaying information on the lens of the Glass. It is voice-operated and linked to the internet.

The beauty of this research project is we are designing the apps and systems for Glass in collaboration with the users so the resulting applications should exactly meet their needs, said Dr John Vines of the School of Computing Science.

Source: Newcastle University

Results out of a study funded by The Michael J. Fox Foundation for Parkinson’s Research (MJFF) have enabled researchers to secure a $23 million grant from the National Institutes of Health (NIH), USA, continuing a repurposed drug approved for hypertension to Phase III testing for slowing Parkinson’s progression.

The trial investigating the compound isradipine will be the most advanced, current study into a disease-modifying therapy for Parkinson’s, an unmet need.

Isradipine is a calcium channel blocker prescribed to treat high blood pressure. Epidemiological data from population-scale studies note a lower incidence of Parkinson’s disease (PD) among people who take this drug.

Furthering PD researchers’ interest, laboratory tests have shown that blocking calcium channels protects dopamine neurons, degeneration of which is one of the hallmarks of Parkinson’s disease.

Source: The Michael J. Fox Foundation for Parkinson’s Research


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Carson City’s WNC baseball beats Eastern Utah |

Carson City’s WNC baseball beats Eastern Utah

Western Nevada College

An unfavorable late-afternoon forecast must have been the reason why the Western Nevada College Wildcats and Utah State University Eastern Golden Eagles completed their nine-inning nonconference baseball game in less than two hours on Thursday afternoon.

"That was probably the fastest nine-inning game I've ever been a part of," said WNC freshman outfielder Bradley Lewis after the Wildcats' 3-0 victory at John L. Harvey Field. "We just wanted to play our game, win and get out before it rained."

The game started an hour earlier than planned due to a threat of late-afternoon thundershowers in the Carson City area.

By flip-flopping its starting pitchers and relievers, WNC is turning the unique strategy into a winning streak. Pitchers Josh Mill, Max Karnos and Connor Zwetsch combined on a five-hit shutout as the Wildcats won their fifth straight game and raised their overall record to 29-20.

"Everything is working right now," Karnos said. "Our pitchers are throwing strikes, our hitters are hitting the ball hard and we're making plays. Hopefully we can keep this going into the playoffs and then we'll have a chance of winning some games."

Mill, a freshman reliever, made his third start for the Wildcats and blanked the Golden Eagles for the first four innings. Karnos, a starting pitcher for most of the season, entered in the fifth inning and needed only 26 pitches to navigate his way through four innings of work and earn his fifth victory in nine decisions. Zwetsch wiggled his way out of a bases-loaded jam in the ninth inning to earn his team-leading seventh save.

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"It felt good commanding my fastball, and I focused on getting ahead of the hitters, doing my job the best I could," Mill said. "We all have our roles; we get switched out every now and then. I would see myself as a bullpen guy still and I'm comfortable of a role anywhere I can fit in."

"Mill threw more fastballs and threw more strikes today, but the biggest difference was we made every play," WNC Coach D.J. Whittemore said.

WNC scored twice in the second on the strength of some extra-base hitting. D.J. Peters started the inning with a double to left field and scored on a triple to center by Kody Reynolds. The Wildcats made it 2-0 on a one-out sacrifice bunt by Blake Morin. Lewis hit a two-out triple but was stranded on third.

In the fifth, Jake Bennett produced WNC's third run, knocking in Morin, who reached on a two-base throwing error.

Karnos entered in the fifth inning and barely worked up a sweat in a quick outing that preserved his arm. He needed only four pitches to retire the Golden Eagles in order in the fifth and seven more in a 1-2-3 sixth inning.

But the seventh started ominously for Karnos and the Wildcats as the first two Eastern Utah players reached base. Karnos, however, took some steam out of the rally by narrowly throwing out Greg Money at third base on a sacrifice bunt attempt.

"I heard third from the dugout, so I turned and chucked it, and I knew I was going to need to rush it," Karnos said. "It was a game-changer."

Eastern Utah freshman pitcher Dakota Carlson, who defeated WNC earlier in the season, quieted the Wildcat bats over the final three innings.

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Paul Gehl, The Newberry Library | Newberry

Paul Gehl, The Newberry Library

Thursday, February 22, 2018

Center for American History and Culture Programs
Chicago: City of Commerce and Design, 1890-1990 Seminar

Collecting Chicago Design: Who Should Do It, When, and Where

Paul Gehl, Curator Emeritus at the Newberry Library, was responsible across nearly thirty years for maintaining and enlarging the Newberry’s collections on printing and design. For this seminar session, Paul will give a brief slide talk about the Newberry’s collections as they document various aspects of Chicago design history and then offer some thoughts about what still needs collecting and who should be doing it. Dan Meyer, Alison Fisher and Tanner Woodford will offer examples from collections they have developed or used, and Paul will lead the seminar participants in an informal discussion about developing priorities, institutional commitments needed, and the role private collectors can play.

The Chicago: City of Commerce and Design, 1890-1990 Seminar is part of Art Design Chicago, an exploration of Chicago’s art and design legacy, an initiative of the Terra Foundation for American Art with presenting partner The Richard H. Driehaus Foundation.

Cost and Registration Information

Newberry Scholarly Seminar papers are pre-circulated electronically. For a copy of the paper, email the Scholl Center at Please do not request a paper unless you plan to attend.


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COLUMBUS (AP) — Columbus is honoring the longest-serving police officer in the city’s history, whose 56 years of service began when officers still checked in via call box.

Lt. Karl Barth was hired by the city on Sept. 25, 1961. He officially retired Monday and will be recognized by the city Division of Police on Friday.

The agency says the 77-year-old Barth took only one sick day in his career. He served under eight mayors and met 11 presidents, beginning with John F. Kennedy.

Barth helped with planning for some of the city’s biggest events over the years, including the annual Red, White & Boom fireworks show, the Columbus marathon, the Arnold sports festival and the Quarter Horse Congress.


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NRHS House Principal, Middle School English Chair Named

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NRHS House Principal, Middle School English Chair Named

September 09, 2017 - 10:41

City School District of New Rochelle

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NEW ROCHELLE, NY -- The New Rochelle Board of Education filled two key administrative positions on Tuesday. Daniel Gonzalez, who served as the assistant principal at Isaac E. Young Middle School, was named the House I principal at New Rochelle High School, and Beatrice Lopez, a former assistant principal in the Bronx, was named the new middle school English department chairperson.

Gonzalez joined the New Rochelle school district in 2004 as a teacher and facilitator at the Jefferson Elementary School. He later moved to IEYMS as administrative dean and became assistant principal in 2016. In taking one of the four house principal positions at NRHS, Gonzalez replaces Gustavo Barbosa, who was named the secondary school social studies chairperson in June.

Superintendent Dr. Brian Osborne said Gonzalez's "track record is excellent. His administrative skills, his diligence and his deep dedication to all of our kids is going to make him a tremendous asset to New Rochelle High School."

Lopez replaces Laurie Marinaro as the middle school English department chairperson. Before coming to New Rochelle, Lopez served two years as assistant principal for the Rafael Hernandez Dual Language Magnet School in the Bronx. She previously taught at several schools in New York City and Florida. In the late 1990s until 2003, she was an adjunct instructor and co-director of the Hunter College Welfare Rights Initiative.

"She demonstrates the kind of keen insight that only comes when someone has truly dedicated themselves to studying every aspect of teaching and learning," Osborne said. "I am confident that her leadership will not only support very effectively our middle school English language arts teachers but will also add to our district administrative team and make a positive impact on the entire district."


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Backyard play equipment is not all slides and swings anymore. Sandboxes are going out of fashion, too, being replaced by spring-free trampolines, ziplines and rock-climbing walls.

DETROIT — It is the kind of tree house that a kid could spend all day and all night inside.
Patrick and Cindy Mifsud's kids have in fact pulled all-nighters in the cedar and pine play set nestled in their backyard in Dearborn Heights, Mich.
The tree house sits a story above ground in an old-growth tree and is supported by beams. The tree was trimmed to accommodate and support the structure as well.
Custom made a decade ago by the Outdoor Fun Store in Canton, Mich., the 10-by-10 foot tree house has five paned windows, a shingled roof and a 9-foot ceiling. The inside, with a kid-sized bunk bed with waterproof mattresses, is made cozier by a television and a fan both mounted into the walls. A ladder leads up to a landing and stairs lead up to the second landing at the door.
A sliding board provides a swift and fun trip from the first landing to the ground.
"Maybe I wanted this kind of a tree house when I was a kid," Patrick Mifsud said with a smile. With two older children who have outgrown the playset, it's now the domain of his 13-year-old son. A custom play set of this intricacy could cost about $25,000, said Dan Wright, owner of the Outdoor Fun Store.
Backyard play equipment is not all slides and swings anymore. Sandboxes are going out of fashion, too, being replaced by spring-free trampolines, ziplines and rock-climbing walls. Modular and custom options are as vast as whatever you can dream up — from swing sets with crawl tunnels or billy goat bridges to clubhouses, "penthouses" or contraptions that could rival the local county park.
Dave Byrum, owner of Kids Gotta Play in New Hudson, Mich., formerly Rainbow Recreation of Michigan, boasts the largest factory in the nation for backyard playsets.
It offers 100 customizable modular sets — which the company refers to as play systems — made of naturally decay-resistant California redwood, western cedar and coast Douglas fir. They run from about $999 to as high as $45,000 or more. The modular equipment grows with the child — pieces for stronger, older kids, such as monkey bars and chain ladders, can be added over time, Byrum said. The typical Rainbow play system runs between $3,000 and $4,000 and costs about $400 to $600 to install.
Sloped or uneven backyards are accommodated with supports and frames to keep the play system level, Byrum said.
Before selecting a design online or from a catalog, make sure to try it. "You've got to come into the showroom and let the kids test it out," Byrum said. "Let the kids loose, see what they like."

Backyard Play Set Basics and Safety

- Wooden playscapes, once typically made of sharp-edged lumber, have been retooled with rounded edges. Bargain hunters and do-it-yourselfers beware of pressure-treated wood because it contains arsenic. Choose cedar instead.
- Platforms, bridges and ramps need guardrails. Children should not play on wet equipment.
- A home play area should maintain a shock-absorbing surface, such as mulch or wood chips, at least 6 feet around and about 3- to 4-inches deep for rubber mulch and 6- to 8-inches deep for wood chips. Be sure to use landscaping fabric underneath any mulch to keep out the grass and weeds.
- Wood chips available at landscaping or gardening stores will suffice. Some play system owners opt for recycled rubber that looks like landscaping mulch. It's offered in a variety of colors from $12.99 to $14.99 for a 30-pound bag.
- Metal swing sets start at about $199 at toy stores or big box merchants. Wooden modular systems can cost $999 and up.

SOURCES: Outdoor Fun Store, Kids Gotta Play


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Dems Need a 'Superconvention'
Earlier superdelegate event could fix Dems' drama: Politico
By Matt Cantor,  Newser User
Posted Feb 24, 2008 3:22 PM CST
Sen. Hillary Rodham Clinton, D-N.Y., gestures to Barack Obama at the debate at the Austin Democratic Debate at the Recreational Sports Center on the University of Texas campus in Thursday, Feb. 21, 2008...   (Associated Press)
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(Newser) – With a tight race and a “crazy quilt of anti-democratic rules” that govern the Dems’ race for the nomination, we need a fair and transparent way to settle the matter. How? Try a July “superconvention,” writes Dan Gerstein in Politico. Superdelegates would gather to hear speeches from each candidate, openly debate the matter themselves—then cast their votes.

To keep the contest out of the feared “smoke-filled rooms,” the event would be televised. Some might call it an unnecessary precursor to the standard convention—but it would allow the winner months more campaigning before the general election. Unrealistic? Perhaps, writes Gerstein, but “maybe an off-the-wall solution is just what is needed to settle this off-the-wall campaign.”


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Starbucks Shrugs Off Big Mac Attack
Company refuses to get steamed as rivals move in for the kill
By Rob Quinn,  Newser Staff
Posted Dec 11, 2008 3:09 AM CST
A man pulls a cart past the Starbucks store inside the Beachwood Mall in Beachwood, Ohio, last month.    (AP Photo/Amy Sancetta)
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(Newser) – So far Starbucks isn't giving two beans about rival efforts to keep the coffee wars piping hot, the Seattle Post-Intelligencer reports. The latest not-so-subtle salvo—a McDonald's espresso billboard declaring "Four Bucks is Dumb" erected within sight of Starbucks' Seattle headquarters—has yet to meet a response, and execs hint they intend to take the high road.

"We're not going to get sucked into the 'my-coffee-is-better-than-yours' type of coffee conversation," Starbucks' chief marketing officer told investors last week. "We're going to play at a much higher level." Analysts expect attack ads to keep coming as the economy slumps, but believe Starbucks will carry on with its current campaign of selected ads promoting social responsibility.


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Airport Hires 'Bird Collie'
'Wildlife management canine' better than horns, whistles at preventing bird strikes
By Rob Quinn,  Newser Staff
Posted May 12, 2009 2:59 AM CDT
A flock of birds, disturbed by a plane's takeoff, takes flight from the side of the runway of a regional airport in New York state.   (AP Photo/The Daily Messenger, Vasiliy Baziuk, File)
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(Newser) – An Oregon airport's specialist is doing a better job at scaring away birds than the horns, whistles and propane cannons she replaced, officials tell the Los Angeles Times. Border collie Filly—official title "wildlife management canine"—is employed to shoo flocks of geese and other winged hazards away from the runway. The collie, which was donated by an animal shelter, is "really good at her job and she really likes her job," said Filly's trainer.


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PANAMA CITY — Greg Yordon with Panama City’s Beltone Hearing Center has been recognized as a Beltone senior master practitioner for top sales of the company’s hearing aids, fitting more than 310 devices and helping 156 people locally in 2016.

Yordon has 27 years of experience as a hearing care practitioner. “Unlike most medical fields, we can see results immediately,” Yordon said in a news release. “Seeing the joy on the faces of the people we help hear better is tremendously gratifying.

“The tears shed in our office are a full spectrum emotional roller coaster. Tears of anxiety of never hearing grandchildren to tears of happiness in hearing grandchildren for the first time. How could someone not love that type of job reward?”

Beltone Hearing Center is at 1031 W. 23rd St.


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Karl Rove In A Snit That Fox & Friends Hosts Ask Him About Code Pink Protester

Reported by Julie - April 18, 2010 -

Back when Congressman Joe Wilson shouted, "You lie," at President Obama, Karl Rove thought it was hilarious, and lauded Wilson as a "good guy." Ignoring the blatant racism and nearly all-white crowds, Rove referred to the tea partiers as "a wide and diverse group," and has supported the Tea Party Movement. Plus, as most of us know, Rove has long been a proponent of doing whatever it takes to achieve an agenda. As reported by the Washington Examiner, the Rove-supported town hall protests were ". . . the return of the Karl Rove playbook: The effort to mobilize the angriest fringe of the Republican base was guided by a conservative dream team that included the same GOP henchmen who Swift-boated John Kerry in 2004, smeared John McCain in 2000, wrote the script for Republican obstructionism on global warming, and harpooned the health care reform effort led by Hillary Clinton in 1993." So given all of this, one would think that Karl Rove is a big believer in people using whatever tactic they think will get the job done, right? Think again -- especially when the target of the protest is Karl Rove himself, and the protester is a Code Pink activist interrupting his book signing. With video.

Rove took umbrage with the hosts of Fox & Friends this weekend for asking him about the Code Pink protester who showed up at his recent book signing. In the past, Rove has acted strangely intimidated -- maybe even frightened -- of the Code Pink protesters.

But this weekend, when asked about the disruption, Rove indignantly sounded off to the giggling Fox & Friends hosts, saying, "This is sad. You people are recycling stuff that happened three or four weeks ago. Please. This is a small blemish on what was otherwise a great trip . . . sort of sad and pathetic people . . . can you imagine being some kind of nut wandering around with handcuffs thinking you've got the right to arrest anybody you want?"

Hmmm . . . no more so than wandering around dressed like this.


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MedMira Expands U.S. Growth Plan with New Equity Investment from OnSite Lab

HALIFAX, March 25, 2015 /CNW/ - MedMira Inc. (TSXV: MIR) is entering into a new CAD $1.1 million equity investment with OnSite Lab Holding AG (OnSite Lab) to support the Company's growth plans in the United States.  These funds will contribute to advancing the Company's progressive sales and marketing drive, including upcoming product launches for its three products under review by the United States Food and Drug Administration, as well as bolstering the Company's physical presence in the United States to support growing sales opportunities.

"The U.S. market is one of the most advanced and highly regulated diagnostic markets in the world; a market that demands innovative products with the utmost quality and reliability. MedMira's patented Rapid Vertical Flow Technology has excelled in this market, enabling rapid testing solutions for both traditional healthcare providers as well as new tools for researchers. This is a clear sign that MedMira's unique and cost effective product offering are the next evolution in rapid testing," said Dr. Kevin Jones, Senior Director, Global Sales and Marketing, MedMira.

As part of the growth plan, a wholly-owned subsidiary focused on sales, marketing, and logistics will provide customer service, expanded sales channel support, as well as product launch planning and implementation.  Direct sales and marketing support teams will be on the ground in the U.S., the Company's most important market, enabling an aggressive strategy roll-out, sales revenue growth, and increased value to MedMira shareholders.

Under the terms of the deal, OnSite Lab will acquire 22,000,000 equity units at $0.05 per unit.  Each equity unit consists of one common share and one common share purchase warrant and is subject to a four month hold period which expires on July 28, 2015.  Each full warrant entitles the investor to purchase one common share of MedMira at $0.10 per share exercisable over four years.  OnSite Lab is the Company's controlling shareholder and has previously made investments in the Company totalling CAD $17.6 million.

About MedMira

MedMira is a leading developer and manufacturer of vertical flow rapid diagnostics. The Company's tests provide hospitals, labs, clinics and individuals with instant diagnosis for diseases such as HIV and hepatitis C in just three easy steps. The Company's tests are sold under the Reveal®, Multiplo and Miriad brands in global markets. Based on its patented Rapid Vertical Flow Technology, MedMira's rapid vertical flow HIV test is the only one in the world to achieve regulatory approvals in Canada, the United States, China and the European Union. MedMira's corporate offices and manufacturing facilities are located in Halifax, Nova Scotia, Canada. For more information visit Follow us on Twitter and LinkedIn.

This news release contains forward-looking statements, which involve risk and uncertainties and reflect the Company's current expectation regarding future events including statements regarding possible approval and launch of new products, future growth, and new business opportunities.  Actual events could materially differ from those projected herein and depend on a number of factors including, but not limited to, changing market conditions, successful and timely completion of clinical studies, uncertainties related to the regulatory approval process, establishment of corporate alliances and other risks detailed from time to time in the company quarterly filings.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

SOURCE MedMira Inc.

For further information: Andrea Young, Corporate Communications, T. 902-450-1588, E.

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News & Opinion

Democracy needs an outspoken, challenging & uncensored press

Our national newsbrands are committed to lively, intense and engaged political debate, which is more important than ever at election time, writes Newsworks' Vanessa Clifford for Campaign

Since Theresa May’s election bombshell, there have been two stories dominating media news – the "will she/won't she" TV debate saga and speculation (particularly in the trade press) about how badly-behaved newspapers could be over the course of the campaign.

Amongst condemnation of political biases and impassioned headlines, as well as questions over newspapers' influence, it's hard to ignore the edge of ever-present irony. If newspapers are irrelevant to readers, then why are they still occupying so much airtime? Why bother taking them to task over their self-declared biases if they hold no weight anyway?

The fact is that newspapers come into their own at times like this. In this country, we're lucky enough to have over 20 national titles, reaching 47 million people with a spread of political views and voices. It’s this unbridled range of opinions which defines newsbrands and sets them apart from broadcasters like the BBC.

Democracy is an outspoken, challenging and uncensored press. You're never going to agree with everything that is written, far from it, but that’s the whole point. Interestingly, it's the titles that most often infuriate the liberal media elite which are consistently most read in the UK.

But whether you're a paid up Guardian member or a die-hard Mail devotee, there should be one thing you can agree on (several actually, but more on that later) – newspapers are indispensable at election time. Why? Precisely because they are not balanced or bland, on the one hand, or downright cynical or mischievous on the other, as tends to be the case where the more exotic, fake-news-infested reaches of the internet are concerned.

The figures back up this role. Recent Newsworks research, conducted in conjunction with Tapestry and focused on 1,000 adults, found that 55% of people learn about politics from newspapers (compared with 19% citing social media). Even 18-24s are more likely to cite newspapers (43%) than social media (41%) as a place where they find out about politics.

I put this down to the fact that our national press are absolutely committed to lively, intense and engaged political debate. What's more, readers understand and value this purpose.

When it comes to election campaigns, we so often get caught up in quantifying newspapers' influence on the electorate, rolling out The Sun's infamous 1992 headline in a variety of guises. This mind-set presumes an old-fashioned, one-sided dichotomy where the press is dictating to the masses. As ever, things just aren’t as linear as that.

In reality, our research shows that people gravitate towards titles which hold similar values to them and rely on them to help navigate a wide range of topics, from politics to pop culture. In fact newspapers emerged as the strongest indicator of how people defined themselves, over age and social class.

Yet there is a difference between drawing on newspapers to help build an understanding of an issue and unquestioningly accepting everything that is written. Reading the opinions of others helps galvanise what we do and don't agree with. It's a relationship built on discourse rather than dictation.

On a broader level (here comes the 'later'), just as the relationships between newspapers and readers are more complex than often presumed, so are the readers themselves. While it's easy and sometimes very necessary to lump people together into clearly defined groups, it can blind us to cross-overs and correlations.

A Conservative voting, Telegraph buying Brexiteer and Corbyn loving, Camden dwelling Metro reader may share little in common on paper, but look closer. By examining what divides and what unites them, shared believes and values can emerge.

In these politically charged times, it can be tempting to take a linear view both of people and the press – in vs out, left vs right, right vs wrong – but this negates the complexities and contradictions that come with democracy. This is what our press embodies. Without it, we lose the texture and authenticity of politics.

So, here we go again? Absolutely.

A version of this piece was first published by Campaign

You're never going to agree with everything that is written, far from it, but that’s the whole point

Vanessa Clifford, CEO, Newsworks
by Vanessa Clifford 10/05/17

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Nexstim logo

Nexstim Plc issues shares in standby equity distribution agreement pursuant to the financing arrangement announced on 21 July 2016, 5 December 2016

05 December 2016

Nexstim Plc (NXTMH:HEX, NXTMS:STO) (“Nexstim” or the “Company”), a medical technology company with a pioneering navigated non-invasive brain stimulation system, announces that, pursuant to the authorisations received at the Company's extraordinary general meeting on 18 August 2016 and the financing arrangement entered into with Bracknor Investment and the Finnish Innovation Fund Sitra which was announced on 21 July 2016, the Board of Directors of the Company has today resolved on issuing 2,333,341 new shares to Sitra with a subscription price of EUR 499,999.98 based on the stand-by equity distribution agreement (SEDA). The Board of Directors of the Company has also decided to list the issued new shares. The new shares will be listed approximately on 9 December 2016. After the issuance, the total number of registered shares in the Company will be 34,517,793.

Martin Jamieson, Chairman and CEO

Further information is available on the website or by contacting:

Nexstim                                                                                +447715163942

Martin Jamieson, Chairman and CEO

UB Securities Oy (Certified Adviser)                                                                         +358 (0)9 2538 0246

Consilium Strategic Communications                                                                     +44 (0)20 3709 5700

Mary-Jane Elliott / Ivar Milligan

About Nexstim Plc

Nexstim is a medical technology company which has pioneered its technology in brain diagnostics with the Navigated Brain Stimulation (NBS) system as the first and only FDA-cleared and CE-marked navigated Transcranial Magnetic Stimulation (nTMS) system for pre-surgical mapping of the motor and speech cortices. Based on the same technology platform, the Company has developed a system called Navigated Brain Therapy (NBT®) which is CE-marked for chronic neuropathic pain, major depression and stroke therapy. Nexstim's shares are listed on Nasdaq First North Finland and Nasdaq First North Sweden. For more information please visit

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Tuesday, September 6, 2016

UK Prime Minister Tells Citizens of European Union Countries: Don't Come to Britain if You Don't Have a Job!

MIGRANTS from the European Union hoping to come to Britain could be banned from doing so unless they have a job under new considerations proposed by Theresa May.

The Prime Minister is looking to bolster the work permit system to ensure EU migrants cannot come to British soil unless they are in some form of employment.

It comes as Mrs May looks to hit back at critics who blasted her for appearing to backtrack on plans to implement an Australian-style points-based immigration system.

But the Premier, speaking at the conclusion of the G20 Summit in China, was forced to concede she is likely to only get “some” or an “element” of control over the free movement of EU migrants into Britain.

The Prime Minister said she will instead balance controls on immigration with getting the "best deal possible for trade in goods and services with the EU".

She added: "What the British people voted for on the 23rd of June was to bring some control into the movement of people from the European Union to the UK. A points-based system does not give you that control."

Mrs May’s acknowledgement has concerned former Ukip leader Nigel Farage, who says he is “worried” by her remarks.

Mr Farage said: “The people were clear in wanting a points-based immigration system, which is why so many went out and voted to leave the European Union. Any watering down from that will lead to real anger.”

The promise to move towards a points-based immigration system was a central pillar of the Leave campaign and Tory Brexit-backing MPs are angry about Mrs May’s “back-sliding”.

Mrs May refused to commit to other key pledges from the EU referendum campaign, including ending Britain's EU contributions and using the money give the NHS an extra £100million a week.

She said: "In terms of immigration numbers as Home Secretary we did start putting the numbers down. They have subsequently risen.

"What we will not have an ability to do is when we come out of the EU have some control on the movement of people coming from the EU into the UK."

Yesterday Britain sent a warship, HMS Diamond, to join an EU fleet committed to preventing migrants from entering European territory.

With the migrant crisis growing, there is growing pressure on Mrs May to invoke Article 50 and commit to pre-Brexit freedom of movement pledges.

- uk express

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Who Said It?

Matt Kenseth's second win in the Chase was hardly easy.  Like his win earlier in October at Talladega Superspeedway, Sunday's Hollywood Casino 400 at Kansas Speedway featured several wrecked cars.  However, in this instance, Kenseth was involved himself when he scraped the wall on Lap 173 trying to avoid a wreck.

"I thought it was over when I got in the fence when Aric [Almirola] wrecked under Mark [Martin]," Kenseth said after recovering for the win.

The No. 17 has now won two of the last three races.  Unfortunately, a 35th-place finish at Dover in late September left Kenseth in an insurmountable hole; he still trails points leader Brad Keselowski by 55 points.

Top 5 Questions for the Chase's Top-5

5. Kasey Kahne (-30) - Even if he makes up 30 points on Brad Keselowski, is there any guarantee he can jump the other three drivers at the same time?

4. Clint Bowyer (-25) - How many of the remaining four races does he need to win to realistically have a chance to overtake the points lead?

3. Denny Hamlin (-20) - Can he rekindle the hot streak that made him a top Chaser in enough time to win the Cup?

2. Jimmie Johnson (-7) - Will he make a run at the Cup without winning a single Chase race?

1. Brad Keselowski (Leader) - How big does Jimmie Johnson look in the rear view mirror and is it intimidating to have the five-time champion right behind him?


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Shaun Buffington ran in a familiar place on his way to winning the first NHMS legends race of the season.  It was the two unfamiliar faces behind him that surprised in the 2013 opener.  Teammates Dean Dezak (second) and Mike Alton (third) both made their first career appearances on the NHMS podium.

Dezak finished comfortably in second, but Alton was forced to contend with three-time NHMS winner, Tom Gray, throughout the 12-lap race.  Gray, a teammate of Buffington's, has had more success, and Alton said after the race that he'd expected that he might get passed at some point.

The race in the Moat Mountain Road Course Legends Series was the first of a doubleheader on the weekend.  The drivers will be back on the 1.6-mile course again at 11 a.m. on Sunday morning.


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NEW YORK >> Private equity firm Sycamore Partners is buying office supplies chain Staples for $6.9 billion.

The companies said Wednesday that shareholders of Framingham, Massachusetts-based Staples will get $10.25 per share.

Staples’ stock closed Wednesday up 77 cents, or 8.4 percent, to $9.93, fueled by a late-afternoon report of a deal. The stock rose another 1.5 percent in extended trading after the deal was announced.

Changing shopping patterns, like the shift to online buying, have hurt office-supplies megastores like Staples. Amazon has become a prime competitor to Staples for corporate customers.

The deal with New York-based Sycamore Partners will allow Staples to adjust to the challenges as a private company.

Staples’ sales have declined 6.1 percent over the past five years to $18.2 billion.

Staples Inc. is the largest “big box” office-supply chain, but it cut the number of stores it runs to roughly 1,600 from nearly 2,300 in 2012, according to FactSet.

Last year, Staples shredded a proposed $6.3 billion merger with rival Office Depot after encountering stern resistance from antitrust regulators that culminated in a federal judge blocking the deal.

Staples confirmed in April that it was exploring a possible sale. Sycamore Partners’ Managing Director Stefan Kaluzny said the deal will help Staples pursue its long-term strategy.

“With an iconic brand, a winning strategy, and dedicated and passionate associates who are deeply focused on the customer, Staples is truly an outstanding enterprise,” Kaluzny said.

The companies said they expect this deal to close by the end of the year.


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Every day, newspapers report on college students’ alcohol abuse problems. For example, The Washington Post published several articles in recent months related to college students’ alcohol abuse including the stabbing of a Bowie State University student by a University of Maryland student. The Chronicle of Higher Education recently published several articles regarding serious problems related to fraternities. Last week, an article in the New York Times reported the arrest of Oklahoma quarterback Baker Mayfield for public intoxication.

Connecticut has 43 colleges and universities. More than 28,000 students will enter or return to our Connecticut State University System this fall 2017. Some will be entering school for the first time and others will be returning for another year. Many students are away from home and parental supervision, and parents are concerned for their welfare. One of the concerns relates to problems associated with alcohol abuse.

Extensive research has shown that college students often inaccurately perceive that their peers consume more alcohol than they actually consume. These inaccurate perceptions of the social norm may encourage students to try to “fit in” by drinking more than they normally would. They already fit in, but they do not know it.

Parents can be proactive and clarify their sons’ and daughters’ misperceptions this summer before they leave for school. Parents can do this by engaging them in discussions throughout the summer regarding college students’ drinking and students’ misperceptions regarding their peers’ consumption of alcohol.

Clarifying students’ misperceptions regarding their peers’ consumption of alcohol often results in students making better choices when confronted with drinking opportunities. Proactive endeavors by parents can facilitate this ongoing process.

C. Kevin Synnott

Assistant professor, Eastern Connecticut State University


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Nick's Cycling and Fitness

Location & Directions 319-752-8480
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> Bicycling Catalog > Bikes > Road > Sport/Performance > Cannondale > Synapse Carbon Women's Tiagra
Cannondale Synapse Carbon Women's Tiagra

Cannondale Synapse Carbon Women's Tiagra

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  • This item is not permitted to be shipped, however it can be purchased online and picked up at your convenience.

Product Details

2017 Cannondale Synapse Carbon Women's Tiagra

Paved, gravel, chip seal—it doesn't matter, it all just adds to the adventure. No matter what impulse drives you, the ynapse's perfect blend of race-day prowess, spot-on handling, and all-day comfort says "get after it". The BallisTec carbon frame features Cannondale's endurance race geometry for a perfect balance between pure race position and upright comfort. The shaped blades and offset dropouts of the tapered SAVE Plus fork allow the front wheel to track smoothly over rough surfaces for amazing comfort and control. With your trusty Shimano Tiagra drivetrain and Tektro brakes, you'll have smooth, precise shifting and powerful stopping on tap. And Cannondale's women's specific components include a smart touches like narrower, short reach bars and a women's saddle to ensure comfort over the long haul.

Features and Information

  • Specifications close open

    Specification Description
    Frame Synapse Women's, BallisTec Carbon, Di2 ready, SAVE PLUS, BB30a
    Fork Synapse SAVE PLUS, BallisTec Carbon, 1-1/8" to 1-1/4" tapered steerer
    Wheels/Rims RS 2.0, 28-hole
    Spokes Stainless Steel, 15g
    Tires Schwalbe Lugano, 700x25
    Crankset Cannondale Si, BB30a
    Chainrings 50/34T
    Chain KMC 10-speed
    Front Derailleur Shimano Tiagra
    Rear Derailleur Shimano Tiagra
    Rear Cogs Shimano HG500 11-32 10-speed
    Shifters Shimano Tiagra
    Handlebars Cannondale C3 Women's Compact Wing, butted 6061 alloy
    Tape/Grips Cannondale Bar Tape, 3.5mm wide
    Stem Cannondale C3 6061 Alloy, 31.8, 6 deg.
    Brake Levers Shimano Tiagra
    Brakes Tektro R741, dual pivot, cartridge pad
    Saddle Selle Royal Seta S1 Women
    Seat Post Cannondale C3 Alloy, 25.4x300mm

    * Subject to change without notice.

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  • Part Numbers close open

    Option Barcode Manufacturer's Part Number Vendor Number
    Black / 48cm 00884603650134 C12407F1048 CSG-C12407F1048
    Black / 54cm 00884603650158 C12407F1054 CSG-C12407F1054
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  • Consumer Reviews close open

    by PowerReviews


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Way High Patrolman

Are you way high?
Now you can be with this humorous policeman uniform. Costume includes Shirt, pants, and hat with dreadlocks. Adult size 33-45.

See more from FunWorld

item #   FW130174    In Stock

Qty:   $33.00

  Shop for More Halloween Costumes and Haunted House Props
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Breakfast for Dinner

I've never been one to really pay attention to proper meal times. I've been known to have mac'n'cheese at any hour of the day, and tonight I decided that nothing sounded better than breakfast for dinner. If you serve this as dinner, I highly recommend pairing it with a margarita.

Tofu, Pepper, and Kale Skillet
(Makes 1 serving)

• 1/2 small bell pepper cut into thin inch long strips.
• 1 serving of lite firm tofu (about 5 oz.) cut into 1/2 in. cubes
• 1/4 c. black beans (I used canned, which were drained and rinsed)
• 1/2 c. chopped baby kale
• 1 large egg
• 1/4 avocado
• 1/2 tsp minced garlic
• season with salt, cumin, and chili powder to taste
• hot sauce and cilantro are optional

1. Heat a small skillet to medium and add a small amount of olive oil to the pan. When it is hot, add the garlic and let cook for about a minute.
2. Add beans, tofu, peppers, and seasoning.
3. Stir the mixture semi-frequently until peppers are soft. Add the kale and cover for a few minutes.
4. Remove the mixture from the pan and place on a plate. Cook the egg to your liking (I prefer over easy) in the same pan then place on top of the kale, tofu, and bean mixture.
5. Garnish dish with sliced avocado, cilantro, and whatever hot sauce you like (I'm a big Cholula fan!).
6. Eat everything ;)

Calories: 310     Carbs: 21g     Fat: 17g     Protein: 23g     Fiber: 10g


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earn money by captcha, captcha service

Forum for making game localization requests via posts/polls/whatever.
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earn money by captcha, captcha service

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Every Horse Has a Story to Tell

When it comes to the best of Hokkaido, delicious local food may immediately come to mind, but we cannot talk about Hokkaido without mentioning the beloved horses on this island. Approximately 8,000 horses are bred in Japan every year, and 70% of this takes place in the Hidaka area, the largest breeding area of the nation. As we have seen a long history of equine sports all over the world, humans and horses live closely together still now.

Located on the hill overlooking the Sea of Japan in Iwanai town near Niseko, the Horse Trust is a non-profit organization that provides a home for retired horses to enjoy the rest of their lives peacefully.

Mr. Sakai’s first encounter with horse racing occurred back in the day when he was a chef in Sapporo and he purchased horse racing tickets for his friend who was really into horse race bidding. Partly because one of his friends was riding in horse racing, he began to develop his passion for jockeys rather than the gambling aspect of horse racing. In spite of attempts to become a jockey himself, his eyesight was not fully qualified so he chose a career as a horse trainer and caretaker. Although he went back to his old job after three years of working with horses, his enthusiasm for equine services remained strong; he was offered a new job in an equestrian center in Niseko which was managed by a large hotel group. After all, he started his dream business in Niseko called Niseko Joba (horse riding) Village fourteen years ago. He reunited with one of the horses retired from the training facility and needless to say accepted his former trainee horse in his equine center, which later led him to increase determination to save as many horses as possible.

Ever since he watched the Horse Trust in Kagoshima on television, he worked very hard towards the goal of launching a similar service to rescue more horses in Hokkaido. Preparing for the organization while running his core business was time consuming and very exhausting. First started out from his family home in Kyowa town, he established the Horse Trust to Iwanai town in 2013 with relocation assistance from the town. There are 30 retired horses, including 2 from the disaster affected area in Fukushima, living happily and independently in the 10 hectares of pasture. Mr. Sakai repeatedly uses the word “horses as economic animals”. Humans unconsciously overlook the fact that many race horses get culled for human consumption as well as pet food once their legendary period is regarded as ended. Therefore, he might continue to search for ways to secure a loving, quality home for more and more horses who need to be acknowledged after retirement, shifting the focus from the mere monetary value of horses. He treats horses as if they were children, sounding like a dormitory leader supervising his beloved students.

He certainly recognizes the importance of promoting regional development through his equine services. “My goal is not to have a petting zoo but to create a natural scenery with horses in it.” The legendary champion Oguri Cap provided a total local economic impact of one million dollars after retirement, by being seen by tourists from all over Japan.

He has dreams about creating a beautiful sight where people could enjoy watching grazing horses with the ocean in the background. He will try to increase the capacity for rescuing more horses in the home, starting with 50 horses first. One of his aims is a contribution to revitalize abandoned land and farms by turning them into productive pastureland. ”I would like everyone to remember the long history and close relationship between humans and horses, almost like a close family member. I am trying my best to rescue and assist as many horses as possible. ”By saying that, I would like more and more people to understand the force behind this service and support.”

Horse Trust Hokkaido in Iwanai is only a one-hour drive away from Niseko.

Share your thoughts.

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NanoDays 2012 Digital Kit

NISE Net offers a digital download of the NanoDays kit, complete with instructions, lesson plans, supply lists, marketing materials, and multimedia files. Consider this option if you do not meet eligibility criteria, are affiliated with an organization that does not hold public events, would like to preview the contents, are located outside the United States, or want to create multiple copies of print resources. NISE Net members are welcome to download a zip file of the free NanoDays digital kit by clicking on the link below. Click here to download the full kit. If you would prefer not to download the entire kit, you are welcome to simply download portions of the kit, as outlined below.

What's in the 2012 digital kit zip file?

I. Digital files of documents to help you get started: Download a zip file of the two guides listed below. (Size: 6.5 MB)

II. Digital files of instructional guides, signs, and supplies for this year's hands-on nano activities: Download a zip file of the activities listed below. (Size: 354 MB)

III. Digital files of marketing and promotional materials: Download a zip file of the materials listed below (Size: 738 MB)

IV. Digital files of staff & volunteer training materials: Download a zip file of the materials listed below. (Size: 9.7 MB)

V. Educational Media

VI. Staff and Volunteer Training Media

To find more information, such as vendor contact info, for any physical resource or consumable material in the NanoDays kit, check under the "Resources tab" of the specific Catalog product's page.


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JCP&L Completed More Than 160 Infrastructure Projects in 2014 to Help Enhance Service Reliability

MORRISTOWN, N.J., Jan. 7, 2015 -- Jersey Central Power & Light (JCP&L) completed more than 160 infrastructure projects and other work in 2014 to help enhance service reliability to its 1.1 million customers in northern and central New Jersey.

"About $250 million was budgeted in 2014 for these projects that help enhance day-to-day service reliability for our customers along with maintaining our system's capability to handle future load growth," said Jim Fakult, president of JCP&L.  "When measuring the average outage duration for customers for 2014, our results show a 17 percent improvement compared to 2013 results, which we can largely attribute to the infrastructure work that has been done this year, and in previous years, to make our system more robust."

Some of the key JCP&L projects in 2014 included:

  • Completing a $15 million expansion of a substation in Monmouth County, which included adding a new transformer, circuit breaker and control building.  The project also provides greater redundancy to benefit 170,000 customers in the county by connecting with existing substations in Red Bank and Tinton Falls.
  • Completing the installation of a new circuit breaker and transformer at a substation in Manalapan in Monmouth County at a cost of $1.2 million.  The project also included adding two new distribution circuits.
  • Completing a $2 million installation of circuit breakers at a substation in Burlington County to provide greater operational flexibility and resiliency for the local and regional transmission network.
  • Completing more than $2 million of upgrades, including adding new circuit breakers, at a substation in Raritan River in Middlesex County.
  • Starting construction of a $10 million expansion of a substation in West Amwell in Hunterdon County.  The project will include a new half-mile transmission line loop to connect the expanded substation with a nearby 230-kilovolt transmission line.
  • Completing nearly $6 million of upgrades on 118 distribution circuits across the JCP&L service area.  The work included installing more resilient fuses, adding larger cross-arms to increase wire clearance and installing fault indicators to help identify problem areas on a circuit to help expedite the restoration process if an outage occurs.
  • Completing upgrades totaling $2.75 million at a substation in Hightstown in Mercer County.  The project included installing a new 115 kilovolt circuit breaker for a transmission line that will run from Englishtown to Wyckoff.
  • Completing installation of equipment in Hunterdon, Monmouth, Morris and Sussex counties that automatically transfers customers to adjacent circuits in the event of an outage.
  • Trimming trees to maintain proper clearances along nearly 3,400 miles of power lines at a cost of approximately $24 million.

Service reliability projects planned for in 2015 include new substations, transmission lines and circuit upgrades.

In 2014, JCP&L made it easier for customers to check the progress of service restoration efforts when they experience a power outage.  The company's 24/7 Power Center outage maps now display the status of crews restoring service after a power outage.  With this enhancement, JCP&L customers can see when crews have been dispatched, when they are working on a repair, and when additional crews or equipment are needed to complete restoration work.

JCP&L customers also can subscribe to email and text message alert notifications to receive billing reminders, weather alerts in advance of major storms, and updates on scheduled or extended power outages.  Customers can also use two-way text messaging to report outages, request updates on restoration efforts, and make other inquiries about their electric accounts.

As part of its storm restoration process, in 2014 JCP&L rolled out two new apps that employees can use on mobile devices to automatically enter damage information into the company's outage management system.  The new hazard app on company smart phones allows responders in the field to electronically document hazardous situations.  Once the hazard assessment is complete, repair crews can use the new damage assessment app on company mobile computers to develop an itemized list of materials and equipment that will be needed to make repairs at damage locations.  The app uses a highly detailed map showing JCP&L's circuits.

JCP&L, a FirstEnergy Corp. (NYSE: FE) subsidiary, serves 1.1 million New Jersey customers in the counties of Burlington, Essex, Hunterdon, Mercer, Middlesex, Monmouth, Morris, Ocean, Passaic, Somerset, Sussex, Union and Warren.  Follow JCP&L on Twitter @JCP_L, on Facebook at or online at

FirstEnergy is a diversified energy company dedicated to safety, reliability and operational excellence.  Its 10 electric distribution companies form one of the nation's largest investor-owned electric systems, serving customers in Ohio, Pennsylvania, New Jersey, West Virginia, Maryland and New York.  Follow FirstEnergy on Twitter @FirstEnergyCorp.

Editor's Note:  Photos of several of the JCP&L infrastructure projects that were completed in 2014 are available for download on Flickr.

Forward-Looking Statements: This news release includes forward-looking statements based on information currently available to management. Such statements are subject to certain risks and uncertainties. These statements include declarations regarding management's intents, beliefs and current expectations. These statements typically contain, but are not limited to, the terms "anticipate," "potential," "expect," "forecast," "will," "intend," "believe," "estimate" and similar words. Forward-looking statements involve estimates, assumptions, known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements, which may include the following: the speed and nature of increased competition in the electric utility industry, in general, and the retail sales market in particular; the ability to experience growth in the Regulated Distribution and Regulated Transmission segments and to successfully implement our revised sales strategy in the Competitive Energy Services segment; the accomplishment of our regulatory and operational goals in connection with our transmission plan and pending distribution rate cases and the effectiveness of our repositioning strategy; the impact of the regulatory process on pending matters in the various states in which we do business including, but not limited to, matters related to rates and pending rate cases, and the Electric Security Plan IV in Ohio; the impact of the federal regulatory process on the Federal Energy Regulatory Commission (FERC) regulated entities and transactions, in particular FERC regulation of wholesale energy and capacity markets, including the PJM markets and also FERC-jurisdictional wholesale transactions, FERC regulation of cost-of-service rates, including FERC Opinion No. 531's revised Return on Equity methodology for FERC-jurisdictional wholesale generation and transmission utility service and FERC's compliance and enforcement activity, including compliance and enforcement activity related to NERC's mandatory reliability standards; the uncertainties of various cost recovery and cost allocation issues resulting from American Transmission Systems, Incorporated's realignment into PJM Interconnection, L.L.C.; economic or weather conditions affecting future sales and margins such as a polar vortex or other significant weather events, and all associated regulatory events or actions; regulatory outcomes associated with storm restoration costs, including but not limited to, Hurricane Sandy, Hurricane Irene and the October snowstorm of 2011; changing energy, capacity and commodity market prices including, but not limited to, coal, natural gas and oil, and their availability and impact on margins; the continued ability of our regulated utilities to recover their costs; costs being higher than anticipated and the success of our policies to control costs and to mitigate low energy, capacity and market prices; other legislative and regulatory changes, and revised environmental requirements, including, but not limited to, possible greenhouse gases emission, water discharge, and coal combustion residuals regulations, the potential impacts of Cross-State Air Pollution Rule, and the effects of the United States Environmental Protection Agency's Mercury and Air Toxics Standards rules including our estimated costs of compliance; the uncertainty of the timing and amounts of the capital expenditures that may arise in connection with any litigation, including New Source Review litigation, or potential regulatory initiatives or rulemakings (including that such expenditures could result in our decision to deactivate or idle certain generating units); the uncertainties associated with the deactivation of certain older regulated and competitive fossil units, including the impact on vendor commitments, and the timing thereof as they relate to, among other things, Reliability Must Run arrangements and the reliability of the transmission grid; the impact of other future changes to the operational status or availability of our generating units; adverse regulatory or legal decisions and outcomes with respect to our nuclear operations (including, but not limited to the revocation or non-renewal of necessary licenses, approvals or operating permits by the Nuclear Regulatory Commission or as a result of the incident at Japan's Fukushima Daiichi Nuclear Plant); issues arising from the indications of cracking in the shield building at Davis-Besse; the risks and uncertainties associated with litigation, arbitration, mediation and like proceedings, including, but not limited to, any such proceedings related to vendor commitments; replacement power costs being higher than anticipated or not fully hedged; the ability to comply with applicable state and federal reliability standards and energy efficiency and peak demand reduction mandates; changes in customers' demand for power, including, but not limited to, changes resulting from the implementation of state and federal energy efficiency and peak demand reduction mandates; the ability to accomplish or realize anticipated benefits from strategic and financial goals, including, but not limited to, the ability to continue to reduce costs and successfully execute our announced financial plans designed to improve our credit metrics and strengthen our balance sheet through, among other actions, our previously-implemented dividend reduction and our other proposed capital raising initiatives; our ability to improve electric commodity margins and the impact of, among other factors, the increased cost of fuel and fuel transportation on such margins; changing market conditions that could affect the measurement of certain liabilities and the value of assets held in our Nuclear Decommissioning Trusts, pension trusts and other trust funds, and cause us and/or our subsidiaries to make additional contributions sooner, or in amounts that are larger than currently anticipated; the impact of changes to material accounting policies; the ability to access the public securities and other capital and credit markets in accordance with our announced financial plans, the cost of such capital and overall condition of the capital and credit markets affecting us and our subsidiaries; actions that may be taken by credit rating agencies that could negatively affect us and/or our subsidiaries' access to financing, increase the costs thereof, and increase requirements to post additional collateral to support outstanding commodity positions, letters of credit and other financial guarantees; changes in national and regional economic conditions affecting us, our subsidiaries and/or our major industrial and commercial customers and other counterparties with which we do business, including fuel suppliers; the impact of any changes in tax laws or regulations or adverse tax audit results or rulings; issues concerning the stability of domestic and foreign financial institutions and counterparties with which we do business; and the risks and other factors discussed from time to time in our United States Securities and Exchange Commission filings, and other similar factors. The foregoing review of factors should not be construed as exhaustive. New factors emerge from time to time, and it is not possible for management to predict all such factors, nor assess the impact of any such factor on FirstEnergy's business or the extent to which any factor, or combination of factors, may cause results to differ materially from those contained in any forward-looking statements. FirstEnergy expressly disclaims any current intention to update, except as required by law, any forward-looking statements contained herein as a result of new information, future events or otherwise.

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eatitWe had our first flu and like some it was deceiving. As alternative medicines ADP (Oregano oil), Immuplex, and increased A, D, C, zinc were very effective for us.

The illness started as gut discomfort with balance issues and nausea as well as those prone to migraines might experience an episode. It goes into fatigue and then lifts very quickly in just a couple days. Also in my case I had an odd desire for port (which lowers the immune system.)

This last bit might sound silly but they have actually found this is very common where viruses effect desires in order to increase survivability. The most famous is Toxoplasmosis aka cat scratch fever aka crazy cat-lady disease. This bugger will cause rats/mice to no longer fear cat urine and actually contribute to them getting eaten by said cat. This is because Toxoplasmosis cannot breed inside a rat/mice, only in a cat. So this little critter actually does mind control on the rat/mice to get them eaten.
Actually this whole concept is so intriguing that I am including it in my next novel, Source Code.

Luckily, this flu critter doesn’t do anything like that. But if you find yourself craving alcohol, sugar, and/or chocolate more than usual – it could be this bug and try to hold out for 24 hours.

As a side note as it will likely come up. Our household doesn’t do flu vaccines for two reasons.
1. Usually the vaccines still use thermosol (mercury) as a cheap preservative and I always found it ironic that folks flip out if you break a thermometer in your hand or heaven forbid swallow it, but bypassing the natural filter (the gut) and injecting it straight into your veins as long as it is labeled “vaccine” – well that’s just dandy. This is what triggered my son’s autism in a 24 hour period and contributed to my wife’s health deterioration (due to this and amalgam fillings which are 60% mercury, and a booster shot which also had thermosol.) It was my fault, even if I was caving to peer pressure.

2. 85% of immunity is the boundary — gut, lungs, skin. Only 15% is T-cells, White blood cells, lymph, etc. Jacking up your internal immunity is like a country stopping terrorism by hiring 3million FBI agents and keeping the borders unmanned. It’s a bit nuts. A much better approach is nutrition and hygiene. Worse everything from asthma to MS is an indicator of an over triggered immune system aka TH2 Dominance.

Of course there is a strong counter argument. My only point is take a few cycles on research as the only “public” pressures are market/profit driven and oddly enough there are as many cons as pros on a flu shot especially if you are immune compromised at all due to illness or age.

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How to Restore your Old House

How to Restore your Old HouseThe word restoration is no doubt very much common for the constructors or the building persons but what about the idea of restoring your old house. Well it sound a bit different but this article will discuss about all the pros and the cons of installing the steps of hiring the contractors for restoring the old house which is very nearby your heart. There are certain things which must be kept in mind at the time of restoring your old house.

Well if you will ask me than it is more appropriate to hire the contractors who possess their specialty in field of restoration of buildings or the old houses. Doing the restoration on your own is very difficult because your profession is not of constructing the old houses or restoring the same.

This article will help you to ascertain certain things which you should keep in mind at the time of restoring your old house and giving it a perfect look which you think is appropriate and attractive according to your perception.

  • It must be pretty clear that why are you undertaking the process of restoration because if your house is not too old than there is no need and question of restoring it but if it is not appropriate you think to be left as such than restoring your house id necessary.
  • It is advisable to take into consideration the history of the house which is going to be restored because every house has their different stories which is not the similar as the other. Its foundations, architecture, base, etc are always different than that of the other houses which has been constructed. So it is advisable to take in to consideration the base and the foundation of your house which is going to be restored.
  • It is definitely depended on the needs and the wishes of the home owners of how they want their old house to be restored. And to comply with your wish of having your house to the dream house, architectures or the contractors must be hired for complying with the requirements of the home owners. Hiring the contractors will help you to ascertain the best of their knowledge which can increase the look as well as the construction of the old house to the new house.
  • Well if you have finally decided for restoring your old house with the new one than you must keep in mind certain things like do not change whole look of the old house and keep certain thing the similar of the old house to the new restored house. There is the reason behind this, it will help your house to look better and this will give you the remembrance of your old house which is converted to the new and the restored house.
  • The historic touch which is preserved in your old house must be maintained in your restored house too. Don’t change the historic windows and the doors which are installed in your old house. This will give your house a fascinating effect which can increase the look of your new restored house.


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Essential Education Costs

The table below - or this attachment for download advises families of the costs requested by the College for the Essential Items provided.
Centrepay is a free direct fee paying service available to parents who receive a centre link payment. Parents will need to fill out a Centrepay Deductions form nominating the amount , payment would be worked out by the amount due divided by number of school weeks, this amount is then doubled as Centrelink payments are paid fortnightly The form is returned to the student campus school for processing


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Newton Free Library kicks off teen summer reading program on June 20 at 7:00 p.m.

Ice Cream Party: Teen Summer Reading Kick-Off, Tuesday, June 20, 7:00 pm, Druker Auditorium: Stop by the Library to celebrate the beginning of summer with ice cream provided by J.P. Licks and Minute-to-Win-It games. While you’re here pick up information on the Teen Summer Reading program. Get involved as we explore the theme, “Build a Better World” with programs throughout the summer.

Log your reading throughout the summer and help us reach our teen goal of 400,000 minutes. If we reach our goal we’ll get a community prize (i.e. Nintendo Switch, bean bag chairs, etc.) that you can vote on for the new teen space. Grades 6-12 (this event is for teens only)


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Not Martha

thing I like: really small hair straightening iron

I needed a straightening iron, but just for my bangs. I didn’t want to spend a lot because the only circumstances under which I see myself straightening all of my hair are those of being really bored and stuck at home. The inexpensive straightening irons you can find at drugstores were monstrously large, and the smaller Chi models were just more than I wanted to pay for something I’m only going to use on days when I’m too lazy to blow dry my hair. And then I found the perfect thing, the 1/2 inch BaByliss mini iron. The plates are only 1/2 inch wide, and the whole iron is about 6 inches long. The description mentions that it would be good for travel, and that the smaller sized plates allow you to get close to the scalp but let’s face it, this baby is made to do bangs.

This review video on YouTube is very helpful and shows the scale of the iron, though I swear it looks large in her hands. The iron is about 6 inches long, like a very skinny stapler. Amazon gave me a delivery estimate of a few weeks but it arrived in just two days. I’d take a picture of to give you a better idea of scale but my camera, TRAGEDY!!, is broken. Here is the Babyliss on top of a dollar bill:

Related note, I was looking around the house for something that would help me keep the iron perched on the corner of my porcelain vanity and found that a square silicone pot holder like this one (which honestly isn’t much good as a pot holder) works great as a grippy and heat proof surface.

· comments [14] · 09-23-2008 · categories:beauty ·

14 responses so far ↓

  • 1 dawn // Sep 23, 2008 at 9:05 am

    Brilliant use for those pot holders! I don’t think I’ve ever used my set of four as they are intended to be used.

  • 2 suzer // Sep 23, 2008 at 9:11 am

    Seriously? Those are my favorite pot holders in the house. They don’t get hot, can go in the dishwasher if needed, and double as potholder/trivet.

  • 3 greta // Sep 23, 2008 at 9:19 am

    back to the flat iron! can you tell me what the plug is like? i have a tiny bathroom with an awkward plug situation and i hate using my current flat iron because i feel like it’s a constant fire hazard. this would be perfect (since i also only use it for my bangs) and i like the idea of being able to pack it easily for travel but am still not sure whether the plug would be any better. Is it the standard chunky hairdryer type plug?

  • 4 megan // Sep 23, 2008 at 9:29 am

    Greta – It’s just a plug. No convertor box of any sort. Does that help? I’d love to take a photo but (TRAGEDY!!) it’s broken.

  • 5 greta // Sep 23, 2008 at 9:38 am

    yay! that’s exactly what i wanted to hear. just a plug is perfect. thanks SO much!

  • 6 Lisa // Sep 23, 2008 at 10:41 am

    I’ve seen those potholders at the Dollar Tree for a dollar!

  • 7 Christine // Sep 23, 2008 at 12:09 pm

    I also hate those pot holders for their intended use so I use the same one, in black, for my hot glue gun mat. The dry glue peels right off it.

  • 8 Dodi // Sep 23, 2008 at 1:07 pm

    Those potholders are lousy. The heat goes right through them. I thought I was somehow using them wrong at first. I finally bought silicone and I hated it. Thankfully I didn’t buy the fancy mitts I was coveting.

    Mostly I use them now to keep plate or bowl from sliding off my lap desk when I eat in my lazy boy :) Didn’t think of them for glue gun mats. Excellent idea.

  • 9 Uyek // Sep 23, 2008 at 1:12 pm

    Oh, I have one of those “pot holders” too. Useless!
    I seem to be on the band waggon when it comes to demoting it to a trivet.
    Glad to read here that it is a design issue not a user error.

  • 10 brook Owens // Sep 23, 2008 at 10:52 pm

    that iron works great! the boys love that at the salon!

  • 11 KarWar // Sep 24, 2008 at 3:21 am

    ooh, i’m gonna get a potholder for my curling iron

  • 12 Susan // Sep 25, 2008 at 5:58 pm

    I need to pick up one of those. I only straighten my bangs and I am trying to move away from doing that as they grow out…I’ve gotten lots of tips and ideas at

  • 13 Julie in Houston // Sep 27, 2008 at 6:44 pm

    Thats so funny that you said that the silicone sqaure pot holders suck! I bought two green ones that were so cute, but they arejust too stiff or someting and I’m always afraid I’ll burn my hand. They do work as trivets though. I think I need to get one of those other ones that look like a duck bill. LOL, that’s the only way i can describe them. You put your fingers in the tip and thumb in the botton. Whatever!

  • 14 Salty // Oct 13, 2008 at 12:48 pm

    Lady I can’t believe you bought that gadget with only 1 review! So brazen! So bold! I admire your tenacity. These days when I search for stuff [I don’t need] on Amazon I white knuckle any purchase that is endorsement-free. Now that it has the NotMartha seal of approval- I may have to put aside my Chi-envy and pony up for this little dandy.

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Press releases

Order repeat prescriptions in time for the bank holiday

Patients in Nottingham City are being urged to check their medicine cabinets and order any repeat prescriptions in plenty of time for the May bank holiday.

“If you know you’ll need to take medication over the bank holiday take a moment now to plan ahead and make sure you have time to get your prescriptions and medication,” said Hugh Porter, Clinical Chair of NHS Nottingham City Clinical Commissioning Group (CCG) and a GP at Cripps Health Centre. “A little forward planning now could save a great deal of inconvenience and help make sure everyone has a relaxing break.”

GP surgeries will be closed on bank holiday Monday and many pharmacies will be operating reduced opening hours.

If you do need medical help or advice over the bank holidays there are a number of places that can help:

If you need help fast but don’t think it’s a 999 emergency, you can call 111. The service is available 24 hours a day, seven days a week, and is free to call from landlines and mobile phones.

If you have a minor illness or injury you can go to an NHS walk-in centre at London Road or on Upper Parliament Street.

If you need advice for minor health problems you can speak to your pharmacist for on-the-spot advice and remedies for a wide range of problems such as stomach upsets, coughs and colds. Details of Nottingham City pharmacies that are open on bank holiday Monday can be found online at www.bit.ly/bank_hol_pharmacies.

Information is also available online via NHS Choices – here you will find a wide range of online health and symptom checkers at www.nhs.uk.

If you think you need to see a GP out-of-hours, telephone 111. The 111 service can put you in contact with the GP out-of-hours service, which can arrange for you to see a doctor or nurse during evenings and weekends if needed.

You should only call 999 or visit the Emergency Department (A&E) in a real emergency. This includes a serious injury or life-threatening problem such as loss of consciousness, severe breathing difficulty, heavy bleeding, severe chest pain, suspected broken bones, deep wounds (e.g. stab wounds), swallowing something harmful or poisonous or a drug overdose.

Published: 18 May 2015


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First Previous 2 OF 3 NextLast

Robert Ferguson

2 of 3 portraits of Robert Ferguson

Robert Ferguson

by William Ward, after Henry William Pickersgill
mezzotint, early 19th century
14 in. x 11 1/8 in. (356 mm x 281 mm) plate size; 18 5/8 in. x 13 1/4 in. (474 mm x 338 mm) paper size
Purchased with help from the Friends of the National Libraries and the Pilgrim Trust, 1966
Reference Collection
NPG D36691

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Sitterback to top

  • Robert Ferguson (1769-1840), Politician; MP for Fife, Dysart, Kirkcaldy and Haddingtonshire. Sitter in 3 portraits.

Artistsback to top

  • Henry William Pickersgill (1782-1875), Portrait painter. Artist associated with 108 portraits, Sitter in 7 portraits.
  • William Ward (1766-1826), Engraver; father of William James Ward. Artist associated with 167 portraits.

Related worksback to top

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Events of 1800back to top

Current affairs

Widespread food riots after poor harvests of 1798-9. Theorist, Thomas Malthus, controversially argues that poverty and food shortages are an inevitable consequence of population growth, challenging assumptions that populousness was a sign of national prosperity and power. His thesis contributed forcefully to the debate over the existing Poor Law.

Art and science

William Wordsworth publishes his Preface to the Lyrical Ballads; a retrospective explanation of his experimental poems written with Samuel Taylor Coleridge. It becomes one of the best-known manifestos of Romantic literature.

Lord Castlereagh, Chief Secretary for Ireland, is the main architect of the Act of Union under which Ireland is merged with Great Britain and the Irish parliament is abolished.
British troops support successful uprising by Maltese against the French.
Napoleon is victorious against Austrians at Marengo and reconquers Italy.

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Bomoseen, Vermont CNA Classes

Bomoseen CNA Training - VT's Free Bomoseen, VT CNA Training Program Directory

You can receive your certification in as little as 3 to 8 weeks.
Bomoseen CNA classes - online & campus-based programs are available.
Admissions Advisor Tip: Don't limit your options. Contact multiple schools to see the differences in what they offer, like financial aid packages.

On-Campus & Online CNA Schools

How to Become a CNA in Bomoseen, Vermont

Since Nurse Aides are needed throughout the Nation, you will be able to secure employment opportunities in any state you become certified. In Vermont, medical field job security is higher than most careers. You can earn your CNA license after completing a training program. CNA course requirements vary by state according to state regulations. However, many CNA programs can be completed in 8 to 12 weeks. Plus, CNA courses are considerably cheaper than attending LPN school and are an excellent way to get started in a healthcare career.

PCT / CNA / CMA - What's the Difference?

This depends on where you live. Some PCT courses include EKG phlebotomy training. Some Patient Care Technician programs also include HHA (Home Health Aid) certification. However, in some work environments the titles CNA and PCT are used interchangably. Some hospitals in Vermont may be hiring Nurse Care Techs (NCT), a position which you can apply for with your CNA license.

CMA can stand for Certified Medication Aide or Certified Medical Assistant, both which perform separate but overlapping duties in the workplace.

How Much Does CNA Training Cost in Bomoseen?

Nursing assistant courses at vocational colleges and allied health schools usually range between $400 and $1200. When choosing a CNA school, learn about all the associated costs required at each institution. Some schools list their program cost as all expenses included. However other schools may also require you to purchase additional materials (such as books, scrubs and materials for your clinicals) which have separate fees from the tuition costs.

CNA Refresher Courses around Bomoseen usually cost around $100-$200.

Need Tuition Assistance?

While many schools do not offer financial aid for students enrolled in their CNA course, some training programs may offer assistance to help with the cost of the course or certification. Also, some CNA employers will even pay for your Nurse Assistant training or reimburse you after you successfully complete your CNA training.

Some employers in Bomoseen will cover a percentage of your CNA tuition; others will pay tuition costs up to a specific dollar amount. Often, new CNAs are required to work a particular number of months at the employer that covered their school bills. Or you may just need to reimburse them for any of the tuition costs they paid on your behalf.

When Can I Start CNA Training in Bomoseen?

Many schools that offer CNA training have new sessions beginning every 6 to 8 weeks. In many areas in Vermont, you can find CNA training starting in November 2017, December 2017, January 2018, or February 2018 available for registration now. Unlike nursing programs in Vermont, you can usually find a school starting a new session of their CNA course fairly quickly. However, some schools offer CNA classes in semester format. At these schools, you may need to wait up 3 or 4 months to start your course.

Becoming a Nurse Aide in Bomoseen a great way to quickly gain experience in the medical field. Check out Vermont CNA Salary info.

More programs in this area

Genesis Eldercare/Mountain View
9 Haywood Ave
Rutland, Vermont 5701
Stafford Technical Center
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The Pines at Rutland
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Addison County Home Health
P.O.Box 754
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Helen Porter Healthcare and Rehabilitation Center
30 Porter Drive
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Patricia A. Hannaford Career Center
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Northlands Job Corps Center
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Randolph Technical Career Center
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Cedar Hill Continuing Care Community
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Mount Ascutney Hospital and Health Center
289 County Road
Windsor, Vermont 5089
River Valley Technical Center
307 South St. (Scott Farr)
Springfield, Vermont 5156
Barre Technical Center
155 Ayers Street
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Berlin Health & Rehab Center
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Rowan Court
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