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Wiz Khalifa Confirms Collaboration With Joey Bada$$

The two have never officially collaborated on wax, so it prompted us to ask for a collaboration (with the prayer hand emoji, of course). Wiz heeded our call. On twitter this afternoon, the KK strain creator confirmed that a collaboration is in the bag, and not only that, “it sounds like album material.” We can’t be mad at that. Shortly after, production collective Cookin Soul caught wind, and jumped in the mix. While this particular... Read More

Wiz Khalifa Sues Former Manager & Rostrum Records For Unfair “360 Deal”

Wiz Khalifa has filed a lawsuit against his former manager, Benjy Grinberg, and his record label Rostrum Records for pressuring him into an unfavorable “360 deal.” Benjy Grinberg began managing Wiz Khalifa in 2004, when the rapper was 16, and he signed him to his label, Rostrum Records, soon thereafter. Wiz dropped Grinberg as his manager in 2014, though it seems that his deal with Rostrum has continued to this day. His contract with... Read More

Wiz Khalifa Arrested At Los Angeles International Airport For Allegedly Using A Hoverboard

According to TMZ,Video of the incident was caught by onlookers and seems to show police slamming the rapper to the ground while yelling “stop resisting.” He does not appear to be resisting at all. On Saturday night, the chart-topping 27-year-old rapper posted a video taken by an onlooker that depicts a swarm of police officers confronting him at Los Angeles International Airport for allegedly using a hoverboard. “This? I didn’t do nothing,... Read More

Juicy J – For Everybody Feat. Wiz Khalifa And R. City

It was only a matter of time before Wiz Khalifa took his shady Amber Rose tweets and went straight to the studio for some more slick talk. After tweeting out “thinkin she a prize? she a pie. everybody get a slice” two weeks ago, the 27-year-old rapper is telling us how he really feels about his ex-wife/baby’s mother with a scathing verse on Juicy J’s new song, “For Everybody.” Right off the bat, the Pittsburgh rapper goes in on mothers... Read More

Wiz Khalifa Reportedly Building A Case Against Amber Rose To Gain More Custody Of Their Son

Wiz Khalifa is reportedly working towards a claim that Amber Rose is an irresponsible parent in an effort to be granted more custody of their son, Sebastian. Yesterday, things got dramatic when Khloe Kardashian decided to call Amber Rose out on her comments regarding Tyga and Kylie Jenner’s relationship. Amber criticized Tyga for leaving his wife and child, and dating a 17-year-old, which made Khloe decided to hop on Twitter and defend her... Read More

Wiz Khalifa – DayToday: Zumiez In-Store

In the latest DayToday vlog, Wiz Khalifa and Taylor Gang take over Zumiez in Burbank, CA, to promote their recent clothing collaboration with Neff. New album ‘Blacc Hollywood’ in stores August 19th. Watch the video below.  Read More

Ty Dolla $ign Ft The Weeknd & Wiz Khalifa – Or Nah (Remix)

Ty Dolla $ign drops off the official visual for the ‘Or Nah (Remix)’ featuring The Weeknd, and Wiz Khalifa. It is produced by DJ Mustard. Directed by Ryan Patrick. Watch the video below.  Read More

Wiz Khalifa – Maan (Video)

Wiz Khalifa returns with an official visual for ‘Maan’, which is his remix of Schoolboy Q’s ‘Man Of The Year’. Directed by David Camarena. New album ‘Blacc Hollywood’ coming soon.   Watch the video below.    Read More

Wiz Khalifa – Smokin Drink (Video)

Here is an unreleased visual from Wiz Khalifa for his track ‘Smokin Drink’. Directed by Gregory Neiser. This is taken from his ‘Cabin Fever 2′ mixtape, which was released in 2012. Watch the video below.    Read More

Machine Gun Kelly Ft Wiz Khalifa – Mind Of A Stoner (Video)

Machine Gun Kelly premieres the official visual for ‘Mind Of A Stoner’ featurng Wiz Khalifa. Directed by Charlie Zwick. Watch the video below.    Read More

Wiz Khalifa – We Dem Boyz

Wiz Khalifa kicks off the campaign for his next studio effort by liberating the first single ‘We Dem Boyz’. It is produced by Detail. Expect the album ‘Blacc Hollywood’ to drop later this year. Listen to the track below.    Read More

Wiz Khalifa – Got Me Some More (Prod. by Young Chop)

After previewing it a while back, Wiz Khalifa unleashes the full and CDQ version of his single ‘Got Me Some More’ produced by Young Chop. New album ‘Blacc Hollywood’ coming in 2014. Listen to the track below.    Read More

Amber Rose Shows Off Her Before And After Pregnancy Profile

Amber Rose celebrated achieving her post-baby weight-loss goal by posting a before and after shot of her body to Instagram. Amber gave birth to her and Wiz Khalifa’s son Sebastian Taylor Thomaz back in February. She’s said previously that her weight-loss is the result of a healthy diet and a vigorous workout routine.  Read More

Grafh Ft Wiz Khalifa – Like Me

Grafh joins forces with Wiz Khalifa for his latest single ‘Like Me’ produced by KE On The Track. This will serve as the first offering from his forthcoming project ‘Pain Killers: Reloaded’. Here is what Grafh had to say about the track and possibly signing to Taylor Gang: “I feel this song exudes a lot of confidence & self assurance. It was just me showing off. We were in LA in the studio, I played it for Wiz and he said ‘yeah thats... Read More

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Friday, May 4, 2007

Let Them Eat Cake!

Who feels the most rewarded here I ask you? The giver? Or the receiver?
I'm having fun sending my pal Bundt cake pans this year, and she is sending me pictures of the results! I of course am drooling over them with coffee in hand, and loving the fact that they are non caloric via cyberspace! I would surely trade a few calories for a bite though. GRUNT.
Ahhh Blima the baker... I miss my dear friend. We see each other once or twice a year ( if lucky) as she resides in Montreal. I'm trying to get her to SnowBird to Pismo soon. We take roadtrips together and make some of the best memories I have. In between these trips we cyber chat, email, and send each other fun things via snail mail. I count myself lucky to have such a love.
You can (and should) check out her website (on the right column) with many of her favorite recipes posted. She loves to cook, and is nothing short of professional, albeit, its generally for friends and family.
She feeds her family, and she feels full.

Jan said...

Those are truly beautiful!! Man... mine never come out that pretty... :-) I bet they taste good too!!!

Anonymous said...

Thank G,
Thanks Jan, yes they are very pretty but its all in the pan.
I really have to stop this for awhile and return to Weight Watchers. :)

DearGina said...

You think maybe that was a hint for me not to send em? ROFL!!

Jan said...

I've baked enough to know while pans make a difference, there's a little more to it than that!! :-) Keep sending those pans Gina!!! :-) And thanks for sharing those! Gorgeous!!

Barb said...

Mmmmmm I can smell them bakingggg!!! I personally know how good a cook...baker Blima is. But Gina...don't sell yourself short. You make the best Mexican food ever. ( Also lots of other food too) xoxox

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Jun 22, 2011

The Grand Girls Anthology

Image: Sabine Delafone
Munich-based publisher Sabine Magnet is the initiator of a cool project called The Grand Girls Anthology, an almanac of women's views on various topics. The anthology is an independent compilation of works by women of all ages and nationalities, and all of its proceeds will be donated to charity organisations supporting girls. Currently, The Grand Girls Anthology is looking for submissions in English or German for the upcoming "Revolution" issue. For more detailed bi-lingual information and submission guidelines please check out the project's homepage.

1 comment:

  1. Sabine Delafon
    ; )


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ON THE HUNT: ‘Several Missing’ After Fire in NYC

Screen Shot 2015-03-27 at 9.08.31 AM

After three buildings went up in flames yesterday evening in NYC, a few people have not been found. Hopefully their lives were not claimed by that fire.

At least two people are thought to be missing after an explosion sent flames tearing through a Manhattan building.

The blast, the result of faulty utility work, caused three buildings to collapse on Thursday, injuring 19 people, four critically.

Fire fighters and medical staff have been working through the night.

The city mayor’s office and the New York Police Department say two people are missing, but note that the situation is fluid.

Earlier, NYPD officials told the BBC that as many as six people were missing. They say that they are investigating all leads, and the number may rise.

Officials said early indications are that the explosion was caused by shoddy plumbing and gas work inside one of the buildings.

Read more: BBC News

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Expired: Makers Square

Makers Square
JTI, with a rich legacy of 128 years, is a premier technological institute in India. With the motto to steer the all-round development of the students here, to create individuals of the highest calibre, who not only go on to have valuable contributions in their field of expertise, but also establish themselves as concerned citizens of the society.

Technovanza, the annual techno-managerial event of VJTI is organized by the students with the motto of ‘Taking Technology to the Society’, which was coined by Dr. A.P.J. Abdul Kalam, a motto to bring together all technical enthusiasts and technical foundations under one roof.

Some Interesting Facts:

· Approximately 35,000 people attend the event over the three days
· More than 170 colleges participated in over 50 events from all over India
· Technovanza received patronage from UNESCO
· Mega Event Robowars with a prize money of 1.25 lacs
· Over 50 start-ups participated in the Innovation Spotlight, the start-up and internship expo held at Technovanza
· Projects like Hexagon city implemented in Japan and Germany
· 2D and 3D Cube Arts for elite speakers and prominent sponsors

Awards:- Rs 30000

Deadline:- 23-12-2016

Take this challenge


text:
Shown off at the 2009 TED conference (aka Mosquito Madness), these Siftables blocks are location aware, motion sensitive, touch interactive and work with other blocks to take on a variety of functions.

Monstermunch posted on the Siftables, which have a 3-axis accelometor that allows for gesture-based controls, and an OLED touchscreen that allows direct user input. Developed in MIT's Media Lab, the blocks communicate with one another while within proximity, meaning they can peform unique functions next to specific blocks. The creator, David Merrill, says this type of physical UI is better suited to the way the brain works, which makes it more intuitive.

In the demo, these blocks, roughly 1.5"x1.5", can be programmed to do anything. They can as a calculator that spit out answers when you put numbers and operation signs in any order and a color blender where you "pour" color blocks into a mixing block. There's even a musical sequencer, where you can rearrange blocks to change patterns, or tap instrument and effects blocks to the sequence to add new sounds on top.

One of the cooler ones was an interactive storybook in which a kid places character and object blocks next to each other, and an improvised, interactive story is projected up on a TV screen.

The thing I like most is that it manages to be forward thinking, while mostly using tech that is currently available for mass production. And they're currently working to patent and commericalize the tech. You can check out more at the Siftables homepage. [Siftables via Monstermunch via BBG]


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Glee TV Show Wiki

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  • Talk:Goodbye

    Don't get me wrong, I love Rachel. But seriously this is really messed up. How about Mike...

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Glee TV Show Wiki

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Silver Aymara Earring

Artesanias de Chile

$ 140.00

  • Silver Aymara Earring
  • Silver Aymara Earring

This product is currently sold out.

Please fill in the form below if you'd like to be notified when it becomes available.

  • Description
  • Impact
    • These sterling silver earrings capture the native wildlife of Chile with their delicate botanical style. The set is adorned with red beads, small medallions and floral engraving to symbolize life and fertility. In a peasant economy where the livelihood depends on agriculture and livestock production, fertility symbols, such as water and flowers, are symbols of abundance, prosperity and welfare. Each set is a beautiful handmade gift made by silversmiths of the Arica and Parinacota regions of Chile.

      • Sterling silver
      • Red bead
      • 1"W x 2"L
    • Artesanias de Chile // Chile

      As well as providing fair employment to their artisans, Artesanias de Chile is also involved in the outreach, training and education of their partners and communities. In teaching traditional Chilean crafts, they share their skills and heritage to a community of otherwise disadvantaged artisans.


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The Godfather Wiki

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    Christopher "Clammy" Abbandando was Genco Abbandando's nephew. Christopher became the owner of...

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Joe walks across a Manhattan street alongside a visually impaired personDirector Joseph Lovett has glaucoma, a disease that robs 4.5 million people worldwide of their vision. After years of slowly losing his sight, Joe decides to take action: to investigate how people all over the country respond to vision-loss. His search begins small, with people Joe meets on the streets of his hometown New York City, and gradually leads him to places and people around the country, of all different ages and backgrounds. Each has a fascinating story about dealing with the vision loss caused by sight-robbing diseases, infections and accidents. As a filmmaker, Joe uses the tool he knows best to gather information, to connect with individuals, and to find answers to share with the world.

Joe covers one eye with his hand on a visit to a low vision therapistGoing Blind interweaves Joe’s story with that of his fellow subjects. Inviting us into the intimate spaces of the visually impaired and blind, Joe takes us into the homes, hospitals, and workplaces of these characters. In his own self-portrayal, he bravely shows how glaucoma is threatening a filmmaker’s entire lifestyle. With determination, Joe does everything he can to slow down the course of his disease from medication to surgeries, visual aids, and the support of family and friends. From his subjects and fellow members of the visually impaired community, Joe receives a guiding light in a darkening world. An array of intimate anecdotes provide a glimpse into the world of low vision and blindness for sighted and visually impaired viewers. A startling 37 million people worldwide have lost their vision, while in the United States alone, Lighthouse International reports that 10 million people are legally blind or visually impaired. Here are the stories of six of them.

Jessica teaching visually impaired students how to make clay sculpturesJessica Jones
Originally from Atlanta, Georgia, Jessica serendipitously met Joe on the streets of her current home, New York City, while she was training her seeing-eye dog, Chef. Jessica was only 32 and an artist teaching in the New York City public school system when she lost her vision in eight months from diabetic retinopathy. Initially, Jessica faced opposition through her illness with a lack of knowledge on both her and her family’s part and a dearth of career opportunities. Determined not to succumb to these obstacles, Jessica finds multiple strategies and technology assistance to cope with her blindness, and finally lands an art teaching position at the Lavelle School for the Blind in the Bronx.

Emmet, smiling, raises his hand while seated at his desk in classEmmet Teran
Eleven-year old Emmet has low vision due to his albinism, a condition he inherited from his father who also lives with low vision. Emmet needs every detail enlarged in order to see, limiting his participation in school, sports, and activities with friends. Recent operations provide hope, yet Emmet takes it upon himself to cope with his illness—participating in an after school comedy troupe. Emmet’s humor is uplifting to himself, and his family and friends.

Steve learning to use a cane on the sidewalkSteve Baskis
Texas native Steve Baskis was 22 and Private First Class in the Army when a roadside bomb north of Baghdad hit his vehicle. In addition to injuries all over his body, Steve suffered a Traumatic Brain Injury (TMI) when shrapnel from the bomb created nerve damage to his eyes, leaving him blind. Going Blind documents Steve’s transition from recovery at Hines Blind Rehabilitation Center outside of Chicago to his new life at his own apartment, cleverly designed by himself for independent living as a blind person.

Pat reads with a visual aidPat Williams
Pat Williams is a legally blind woman, who struggles to bridge her place between the world of the sighted and that of the visually impaired. As a program support assistant at the New York City center for Veterans Affairs, Pat has found ways to adapt her work environment to her own needs. Yet at times it is necessary for her to receive help from family for daily needs. For five years of Pat’s life, she was afraid to go outside because of her condition. Throughout the film, Pat works to strike a balance between relying on family and remaining a fiercely independent woman who does not let her disability define her.

Peter shows Joe photos of his architectural projectsPeter D’Elia
An 85-year-old working architect suffering from macular degeneration, Peter D’Elia has been slowly losing his vision over the past 10 years. His career was in crisis when he noticed that his vision was failing even in his good right eye. Through passion, stamina, and an open mind for new opportunities, Peter finds the drive to continue working, trying new medication for his illness, and fighting to restore his sight. Despite vision loss, Peter continues to pursue his love of architecture at his home in New Jersey.

Ray guides Joe through his workspace at The Seeing EyeRay Kornman
At age 29, while at a routine doctor’s visit to renew his contact lens prescription, Ray Kornman discovered he had retinitis pigmentosa, an incurable eye disease that would leave him blind by the age of 40. In Going Blind, Ray discloses his initial feelings of hopelessness and vulnerability before learning of the various services available for the blind. Ray’s life changed when he got his guide dog at the Seeing Eye in Morristown. Now, secure in his condition and content with his life, Ray’s mission is to spread the message about the power of guide dogs.


text:
670c Home - Gospel Warriors Ministries

Who We Are?

Welcome to Gospel Warriors Ministries Website. Our desire is to encourage you in your walk with Christ, and to hopefully impart something to you to help you grow into a mature and complete christian fully equipped and able to embrace and fulfill your destiny.
The purpose of our website is to offer word based topics to challenge you, and to inform and update you on activities that we perform in reaching the lost and hurting.
We are a 501(c)3 non profit organization, and although our outreach is small, the principles of integrity foundate every aspect of our efforts.
"A Ministry of Integrity"


text:
Make a blog

2 years ago

How to Succeed like Perry Belcher

Every internet marketer likes to become successful. But, success is not something that you can acquire within several weeks or days. If you like to succeed, you must know the factors you should take note for you to get rid of any problems in the end. If you're just starting with your online venture yet you don't have a clue on where to get started, there are several ways for you to become successful.

Developing a business plan is one of the best ways to succeed in the today's online market. You have to bear in mind that every business requires a marketing plan. Without this, you won't stay on the right direction because you don't know the things you want to achieve. Creating a business plan is not a hard task. However, for you to create an effective one, you must always take for consideration of your goals because this will lead you to success. Bear in mind that if you don't have a clue about the things you want to accomplish, you will not search for the right way to success. Therefore, create a business plan before consider deciding to launch your business.

Focus and dedication is another important thing you should need to be a successful online marketer. You are only person who is molding your own future. If you will not focus on your business and you will just go with the flow, you could not get your preferred results. You need to strive for you to succeed. Clicking go there likely provides aids you might give to your pastor. According to Perry Belcher, you need to be creative or innovative. When you are managing a business, you also have to create new things for you to stay ahead of the competition from some businesses. By making a trend in the industry, success will follow.

You don't actually need to follow the latest trends. But, for beginners, it is a good idea to stick with the trends as this can be risky to create a new trend. But, if yo


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Do you have the skills employers want?

Employers usually want to employ people with a particular skill or set of skills. In this article we define what a skill is and how can you show that you have the skill(s) that employers want.

What is a skill?

According to, a skill is defined as “the ability, coming from one’s knowledge, practice, aptitude, etc., to do something well.”

How can you identify the skills employers want in Zambia?

Start by looking at the job advertisements listed on Employers use job advertisements to show applicants the skills required. Use the job advertisements to identify the most important skills, remembering to include soft skills (such as communication, tact, diplomacy etc.) as well as hard skills such as qualifications and experience. It may help if you write down a list of the skills required. This will help you to identify the skills you already possess and provide information on skills that you may need to develop.

How can you identify your own skills?

A great way to identify your own skills is to conduct a quick skills assessment. You can find out how to conduct a skills assessment in the article listed below. You may also want to read the article on transferable skills.

How can you demonstrate your skills in your application?

Remember that the employment market in Zambia is extremely competitive and in order to be successful you need to create a carefully planned application. The good news is that now you should have a better undestanding of (a) the skills employers want in Zambia and (b) your own skills. Now you just need to demonstrate these skills in order to pursuade the employer that you are the best candidate for the role. To find out how you can demonstrate your skills in your application check out the article below.

What if I am missing skills?

If you are misssing a skill that is required by an employer then you may need to take some action that will help move you in the right direction. This action could include udertaking additional education, experience or skill-building activities. If you possess most of the skills required it may still be worth applying, however this will depend on the of the importance of the skill that is missing.

To view a range of FREE online courses check out:

Additional Information

To find more free careers advice in Zambia just visit: Careers Advice

Search for Jobs

To search for the latest jobs in Zambia visit:


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Alzheimer's disease (AD) affects 20% of those over the age of 75 and 50% over the age of 85. It is difficult to identify early stages of AD and there are no methods to quantitatively follow disease progression. Therapies to slow AD or to cure AD are also absent. One of the neuropathological features of AD is the neurofibrillary tangles made of abnormally phosphorylated tau protein. The discovery of mutations in the tau gene that cause age-related neurodegenerative diseases, such as frontotemporal dementia, has led to research showing that (1) abnormally phosphorylated tau is sufficient to cause disease and (2) neuronal death is caused by abnormal tau. Moreover, AD is now considered a "tauopathy". To discover new biomarkers and therapeutics for AD and other tauopathies, it is critical to determine how tau causes disease. While many investigators have focused in the well-known property of tau as a microtubule-associated protein, we have focused on identifying new properties for tau, as there are many microtubule-associated proteins that have no connection to AD. We have found that tau associates with Src-family non-receptor tyrosine kinases and is tyrosine phosphorylated. We have also found that tau can up-regulate kinase activity and that both abnormally phosphorylated and mutated forms of tau can associate more strongly with Fyn, a Src-family kinase. In fact, other investigators have shown that deleting Fyn is neuroprotective for AD in mouse models. Because tau is tyrosine phosphorylated, we investigated the possibility that tau might function as a signal transduction protein. We found that tau potentiated NGF-induced MAPK and AP1 activation in neuronal cells and that phosphorylation of tau at thr231 and tyr18/tyr29 were critical for this new property. Microtubule binding was not involved. In addition, we found that tau associated with the protein tyrosine phosphatase SHP2 in an NGF-dependent manner. In this application, we propose to investigate the tyrosine phosphorylation of tau using two approaches.
In Specific Aim I, we will determine if deletion of Fyn from a tauopathy mouse model alters the tau pathology and neuronal viability in the model. We will also determine if the behavior of the mouse is altered.
In Specific Aim II, we will investigate the function of abnormally phosphorylated tau. Specifically, we will investigate the role of phosphorylation in the interaction between tau and SHP2 as well as the functional significance of the interaction.
In Specific Aim III, we will determine if SHP2 is activated in AD. SHP2 and MAPK activation will also be investigated in a mouse tauopathy model.
These aims will (1) advance our knowledge of the mechanisms undertaken by abnormally phosphorylated tau and (2) determine if these mechanisms are taking place during neurodegeneration. Abnormally phosphorylated tau is the earliest sign of neurodegenerative disease and our investigation aims to identify the earliest steps taken towards the neuropathogenic process. Our data will aid in the identification of new targets for disease therapeutics and new biomarkers for tracking disease progress.

Public Health Relevance

Alzheimer's disease is the sixth leading cause of death in the United States and caring for Alzheimer's disease patients costs close to $200 billion per year. Our laboratory is investigating tau protein, a critical component in Alzheimer's disease neuropathology. Our goal is to identify mechanisms activated by tau that lead to cell death. The data will suggest new targets for disease therapeutics and new biomarkers for tracking disease progress.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Research Project (R01)
Project #
Application #
Study Section
Special Emphasis Panel (ZRG1-MDCN-F (03))
Program Officer
Miller, Marilyn
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Iowa
Internal Medicine/Medicine
Schools of Medicine
Iowa City
United States
Zip Code
Bhaskar, K; Hobbs, G A; Yen, S-H et al. (2010) Tyrosine phosphorylation of tau accompanies disease progression in transgenic mouse models of tauopathy. Neuropathol Appl Neurobiol 36:462-77
Leugers, Chad J; Lee, Gloria (2010) Tau potentiates nerve growth factor-induced mitogen-activated protein kinase signaling and neurite initiation without a requirement for microtubule binding. J Biol Chem 285:19125-34
Bhaskar, Kiran; Yen, Shu-Hui; Lee, Gloria (2005) Disease-related modifications in tau affect the interaction between Fyn and Tau. J Biol Chem 280:35119-25
Lee, Gloria; Thangavel, Ramasamy; Sharma, Vandana M et al. (2004) Phosphorylation of tau by fyn: implications for Alzheimer's disease. J Neurosci 24:2304-12


text:
Each brain imaging modality reports on a different aspect of the brain (e.g. gray matter integrity, blood flow changes, white matter integrity) and each has strengths and weaknesses. However the vast majority of studies analyzes each imaging modality separately and interprets the results independently of one another. Many mental illnesses, such as schizophrenia, bipolar disorder, depression, and others, currently lack definitive biological markers and rely primarily on symptom assessments for diagnosis. One area which can benefit greatly from the combination of multimodal data is the study of schizophrenia. The brain imaging findings in schizophrenia are widespread and heterogeneous and have limited replicability. We show evidence that, in part, the lack of consistent findings is because most models do not combine imaging modalities in an integrated manner and miss important changes which are partially detected by each modality separately. Combining multimodal imaging data is not easy since, among other reasons, the combination of multiple data sets consisting of thousands of voxels or time points yields a very high dimensional problem, requiring appropriate data reduction strategies. There are two important areas that we focus on in this new phase of the project. First, we will focus on developing data fusion strategies that will leverage our initial success in developing ICA-based tools for combining multiple tasks and modalities. We will develop and validate approaches which can scale easily from one to many different data types. In the first funding period we focused mainly on pair-wise combinations of multimodal data. However, the results have convinced us that allowing higher order relationships is also important (e.g. we show pilot data in which using 3-way relationships improves our ability to discriminate schizophrenia and control groups). In this proposal we will significantly expand this work and develop novel methods to efficiently exploit high-order joint information not just pair-wise. Next, we will develop new tools that will identify correspondences among modalities. For example we show that structural and functional patterns of covariation are in some cases remarkably similar to one another and in others cases quite distinct and these relationships can predict diagnosis. We will thoroughly test our approach using a well characterized data set involving multiple illnesses that have overlapping symptoms and which can sometimes be misdiagnosed and treated with the wrong medications for months or years (schizophrenia, bipolar disorder, and unipolar depression). As before, we will provide open source tools and release data throughout the duration of the project via a web portal and the NITRIC repository, hence enabling other investigators to compare their own methods with our own as well as to apply them to a large variety of brain disorders. 36

Public Health Relevance

Each brain imaging modality reports on a different aspect of the brain with different strengths and weaknesses and there are now literally thousands of putative imaging biomarkers. This project will develop multivariate methods which use higher order statistics to combine diverse information in a scalable manner, identify correspondence among data types and also provide a sophisticated data sharing and management system.

National Institute of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Research Project (R01)
Project #
Application #
Study Section
Special Emphasis Panel (ZRG1-NT-B (08))
Program Officer
Pai, Vinay Manjunath
Project Start
Project End
Budget Start
Budget End
Support Year
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Bridwell, David A; Steele, Vaughn R; Maurer, J Michael et al. (2014) The relationship between somatic and cognitive-affective depression symptoms and error-related ERPs. J Affect Disord 172C:89-95
Çetin, Mustafa S; Christensen, Fletcher; Abbott, Christopher C et al. (2014) Thalamus and posterior temporal lobe show greater inter-network connectivity at rest and across sensory paradigms in schizophrenia. Neuroimage 97:117-26
Bridwell, David A; Kiehl, Kent A; Pearlson, Godfrey D et al. (2014) Patients with schizophrenia demonstrate reduced cortical sensitivity to auditory oddball regularities. Schizophr Res 158:189-94
Allen, Elena A; Damaraju, Eswar; Plis, Sergey M et al. (2014) Tracking whole-brain connectivity dynamics in the resting state. Cereb Cortex 24:663-76
Castro, Eduardo; Gomez-Verdejo, Vanessa; Martinez-Ramon, Manel et al. (2014) A multiple kernel learning approach to perform classification of groups from complex-valued fMRI data analysis: application to schizophrenia. Neuroimage 87:1-17
Calhoun, Vince D (2014) Brain networks: the next steps. Comment on: "Understanding brain networks and brain organization" by Luiz Pessoa. Phys Life Rev 11:440-1
Plis, Sergey M; Sui, Jing; Lane, Terran et al. (2014) High-order interactions observed in multi-task intrinsic networks are dominant indicators of aberrant brain function in schizophrenia. Neuroimage 102 Pt 1:35-48
Chen, Zikuan; Liu, Jingyu; Calhoun, Vince D (2013) Susceptibility-based functional brain mapping by 3D deconvolution of an MR-phase activation map. J Neurosci Methods 216:33-42
Bridwell, David A; Wu, Lei; Eichele, Tom et al. (2013) The spatiospectral characterization of brain networks: fusing concurrent EEG spectra and fMRI maps. Neuroimage 69:101-11
Gollub, Randy L; Shoemaker, Jody M; King, Margaret D et al. (2013) The MCIC collection: a shared repository of multi-modal, multi-site brain image data from a clinical investigation of schizophrenia. Neuroinformatics 11:367-88

Showing the most recent 10 out of 44 publications


text:
IN VITRO vs. IN VIVO FUNCTION The most reliable approach for establishing the in vivo function of an enzyme is by genetics coupled with biochemical analyses. Numerous examples demonstrate that the physiological roles assigned to enzymes based on in vitro reactions they catalyze are incorrect. In perhaps tne most famous example, Arthur Kornberg discovered DNA polymerase I which was thought to be the sole E. coli DNA polymerase and, therefore, must be responsible for DNA replication [2]. However, mutants lacking DNA polymerase I grew and made DNA normally;hence, DNA polymerase I could not be the replicatlve polymerase [3, 4]. The replicatlve polymerase later was shown to be DNA polymerase 111, a much more complicated enzyme that, given the reaction conditions and template used for DNA polymerase I, is virtually inactive. However, mutants of polymerase I are super-sensitive to both UV and mutagens, showing that the in vivo role of polymerase I is DNA repair [5]. Kornberg desen/ed the Nobel Prize, but the fact remains that the physiological role of DNA polymerase I was in error due to the lack of genetics. A less famous but immediately relevant example of the in vivo ambiguity of an In vitro assigned function is provided by the computationally predicted and experimentally verified assignments of the N-succinyl Arg/Lys racemase [6] and L-Ala-D/L-Phe dipeptide epimerase [7] functions to members the MLE subgroup of the enolase superfamily. In both examples, Jacobson (Computation Core) predicted substrate promiscuity that was confirmed by enzymatic assays (EN Bridging Project). However, for both enzymes, the identity of the in vivo substrate as well as the physiological importance of the reaction is unknown. The Microbiology Core will apply genetic analyses and metabolomics to determine the in vivo roles of enzymes for which the In vitro functions are predicted by the Computation Core and verified by the Bridging Projects. Enzymes that emerge from the bottom of the funnel of Figure 1 in the Program Summary may be active with one, a few, or many related substrates with varying catalytic efficiencies. Which substrate(s) do they use in vivo? A combination of bacterial genetics, phenotypic characterization, and metabolite analysis will enable the physiological roles of the EFI targets to be evaluated and assigned.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
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Project #
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University of Illinois Urbana-Champaign
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Mashiyama, Susan T; Malabanan, M Merced; Akiva, Eyal et al. (2014) Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere. PLoS Biol 12:e1001843
Akiva, Eyal; Brown, Shoshana; Almonacid, Daniel E et al. (2014) The Structure-Function Linkage Database. Nucleic Acids Res 42:D521-30
Zheng, Heping; Hou, Jing; Zimmerman, Matthew D et al. (2014) The future of crystallography in drug discovery. Expert Opin Drug Discov 9:125-37
Wichelecki, Daniel J; Graff, Dylan C; Al-Obaidi, Nawar et al. (2014) Identification of the in vivo function of the high-efficiency D-mannonate dehydratase in Caulobacter crescentus NA1000 from the enolase superfamily. Biochemistry 53:4087-9
Dong, Guang Qiang; Calhoun, Sara; Fan, Hao et al. (2014) Prediction of substrates for glutathione transferases by covalent docking. J Chem Inf Model 54:1687-99
Wichelecki, Daniel J; Vendiola, Jean Alyxa Ferolin; Jones, Amy M et al. (2014) Investigating the physiological roles of low-efficiency D-mannonate and D-gluconate dehydratases in the enolase superfamily: pathways for the catabolism of L-gulonate and L-idonate. Biochemistry 53:5692-9
Bouvier, Jason T; Groninger-Poe, Fiona P; Vetting, Matthew et al. (2014) Galactaro ?-lactone isomerase: lactone isomerization by a member of the amidohydrolase superfamily. Biochemistry 53:614-6
Wichelecki, Daniel J; Froese, D Sean; Kopec, Jolanta et al. (2014) Enzymatic and structural characterization of rTS? provides insights into the function of rTS?. Biochemistry 53:2732-8
Pandya, Chetanya; Dunaway-Mariano, Debra; Xia, Yu et al. (2014) Structure-guided approach for detecting large domain inserts in protein sequences as illustrated using the haloacid dehalogenase superfamily. Proteins 82:1896-906
Kumar, Ritesh; Zhao, Suwen; Vetting, Matthew W et al. (2014) Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine. MBio 5:e00933-13

Showing the most recent 10 out of 49 publications


text:
Graduate Studies
GRE Verbal Practice | TOEFL Practice Test | Online Degrees | Courses | Universities in USA | Search

GRE Vocabulary Flash Cards

line (of police acting as a guard)

While no protests were reported Saturday, residents said police continued to cordon off streets leading to government buildings in the seats of the two counties, known as Zhenglan and Xiwu in Chinese or Shuluun Huh and Ujumchin in Mongolian. ...

The cordon around the Christchurch CBD's most quake-damaged buildings is to shrink again tomorrow. A section of Zone 6, a cordoned area on the north side of the Avon River, is to open from 12pm. The area is bounded by Peterborough, ...


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A life of ease is a difficult pursuit.
-- William Cowper

Thursday, September 6, 2012

Live with enjoyment

Enjoyment is not something you take. It is something you give.

Enjoyment is not a function of your circumstances. Enjoyment is a choice you can make, regardless of the circumstances.

When you choose to enjoy where you are, it opens your eyes to the positive possibilities. When you decide to enjoy what you’re doing, your effectiveness skyrockets.

Enjoy your day, and you add joy not only to your own life but also to all of life around you. Enjoy who you are, and from who you are will flow great and meaningful value.

Give the gift of your own genuine enjoyment. Demonstrate your gratitude and immense respect for life by truly enjoying each precious moment.

Instead of reacting to life with frustration or disappointment or anger, make the choice to enjoy what life brings your way. Live with enjoyment, and give the best of who you are.

— Ralph Marston

Become a member and replace these ads
with your own positive affirmations.


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My Nonprofit Reviews

Akiva - charity reviews, charity ratings, best charities, best nonprofits, search nonprofits

773 profile views
1 reviews

Review for Partners in Torah, Passaic, NJ, USA

Rating: 5 stars

A number of years ago, I responded to an impassioned plea by the founder of this wonderful organizaion to get involved in being a mentor to another Jew who has expressed an interest in learning more about his heritage. Getting involved in this way has fostered a bond of friendship and has enabled a connection of spiritual growth for my partner and I; I can't imagine how this could happen without having Partners In Torah as the forum which facilitated this connection. I have been learning with my current partner in Torah for many years now. So much good has come out of our relationship; I have tried to help him thru many issues in his spiritual progression; he has enriched my life with his sincerity and goodness. This organization beams with "success stories"; it is truly a win-win organization for all those involved.

I've personally experienced the results of this organization in...

seeing the transformation of people connecting to their priceless heritage.

What I've enjoyed the most about my experience with this nonprofit is...

the ability to learn and befriend a complete stranger by encouraging and sharing our common heritage.

The kinds of staff and volunteers that I met were...

truly wonderful, non-judgemental people.

If this organization had 10 million bucks, it could...

bring the light of Torah to so many more Jews thirsty for it.

How frequently have you been involved with the organization?

About every week

When was your last experience with this nonprofit?

Role:  Volunteer & I became a volunteer mentor to learn Torah with a Partners In Torah student.


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My Nonprofit Reviews

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1 reviews

Review for Bayou Land Conservancy, Houston, TX, USA

Rating: 5 stars

Cynthia Salvaggio and her crew at Bayouland Conservancy helped fund my students to their only field trip this year. Bayouland Conservancy taught my students and myself about science topics that brought us into the outdoors. It was wonderful because my students got to experience many things at the conservancy such as view a decomposing deer, digging up nonnative plants, scavenger hunt, and learning about certain types of plants and trees. the experience was awesome and my kids really enjoyed being able to go outside the city limits to see what nature has to offer them!

I've personally experienced the results of this organization in...

Being outside doing the same activities as my students were doing was an awesome experience. It built relationships with my students that you cannot bring into the classroom. We laughed and learned a lot of cool new stuff.

If I had to make changes to this organization, I would...

Do nothing.

Role:  Client Served & I helped watch over my students do the activities.


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Archives for Ergonomic Chair

7 Tips for Choosing the Best Ergonomic Chair

Choosing the right ergonomic chair for your body type is not the easiest task, but with a little research and helpful advice you will find the chair of your dreams. The following tips provide you with a base of what to look when shopping for an ergonomic chair, whether it is for home or the office.

Tip #1: All ergonomic chairs are not created equal. The saying “you get what you pay for” definitely applies to ergonomic chairs as well. You will find chairs ranging in price from $50 to $1000 and everywhere in between. Some will fall apart in a year and some will last a lifetime. Make sure you set your budget as high as you can if you want the best, most comfortable ergonomic chair.

Tip #2: One size chair does not fit all users. When looking for an ergonomic chair the more adjustable features it has the better. Not only will it make it easier for you to adjust the chair to your body type but if the chair you buy is going in a place where others might use it also it will make adjusting it to fit their needs that much easier.

Tip #3: Pay attention to the size and shape of the actual seat cushion and back rest. Most ergonomic chair manufacturers have a variety of seat sizes to choose from and the size you need is determined by, you guessed it, the size of your body! This is the first place ergonomic chairs differ from standard computer chairs because standard chairs rarely come in more than one size.

Tip #4: Can the height and tilt of the seat cushion be adjusted? Most chairs allow you to adjust the height easily but being able to adjust the tilt of the seat is a special feature that usually only ergonomic chairs have. Being able to set the tilt where you want it allows for even grater comfort than height adjustability alone.

Tip #5: Does the back cushion have multiple depth settings? A back cushion that only stays in one place is not very ergonomic so most ergonomic chair manufacturers include a feature that allows you to adjust the depth, or tilt, of your back support cushion. This is another adjustment that will help get your body in the proper posture for extended computer use.

Tip #6: Opt for the adjustable arms feature to really bring your seating experience to a whole new level. Adjustable chair arms allow you to change the height and tilt of the arms so they can fit users with various heights and seating postures.

Tip #7: Make sure the chair you end up purchasing is covered under warranty for at least one year. Good chair manufacturers will always include a warranty and they stand by their products 100%, it’s the less expensive brands you need to watch out for.

Minimizing Injuries With Ergonomic Chairs

Biotechnology experts claim that in the course of an office-based worker’s career, he or she would be spending 80,000 hours sitting on a chair, usually in front of a computer. Not a lot of people know that sitting for prolonged periods causes more injuries to the body than standing. To prevent such injuries, many offices now furnish their premises with ergonomic chairs for the use of their employees.

It is important to use ergonomic chairs in the workplace. As stated above, sitting for long hours can harm the body more than standing does. It is because while standing, the pressure of supporting the body is evenly distributed along the spine. The circulation of blood in the body is unhindered, and the spine freely receives the nutrients that it needs to remain fluid and flexible.

Sitting, however, makes the pressure of supporting the body uneven along the spine. The brunt of the pressure is received by the lumbar portion of the spine, which is the lower back. Blood circulation is blocked, and so the lower portion of the spine does not receive enough nutrients, causing it to harden. Preventing the lumbar portion of the spine from hardening is one of the health problems that ergonomic chairs aim to address.

However, buying even the best-designed and the most expensive of ergonomic chairs would be useless if the people using them do not sit on them correctly. Aside from using ergonomic chairs, a few minor adjustments to a person’s sitting habits will greatly reduce the cumulative damages that prolonged sitting can do to the spine.

For example, in the case of lower back pain, it can either mean that the lumbar portion of the spine is not being supported, or there is too much pressure on the vertebrae. It could also be that the muscles of the thigh are pulling at the spine because the legs are dangling and the feet are not flat on the floor. To address this problem, the backrest of the ergonomic chairs being used should be tilted forward slightly so it curves against the lumbar area of the spine. Another adjustment that should be made on the ergonomic chairs being used is to adjust the height of the chair itself so the legs are not dangling.

In the case of neck strain, tensed shoulders and pain in the upper back, it means the head is tilted too far forward or too far back. The arms also are not being supported. The adjustments that need to be made on the ergonomic chairs being used are, first, tilting the seat and the backrest either forward or backward so that the back, neck and the head are in a completely vertical position. As for the arms, the armrests of the ergonomic chairs being used should be raised or lowered so the arms are resting upon them comfortably.

If pain is experienced on the buttocks, then it means that there is too much pressure on the person’s rear. The ergonomic chairs being used should then be tilted so that the people using them are sitting deeper into the chair. The back of the thighs should also be in the seat pan.

Even the best and the most expensive ergonomic chairs cannot help reduce the damage sustained to the body if they are not being used correctly. Only a few minor adjustments to these chairs and to the person’s sitting habits are necessary, but the effects shall be great in the long run.


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B-Greek: The Biblical Greek Forum

B-Greek is an electronic conference designed to foster communication concerning the study of the Greek Bible.

Classics List: Discussion of Greek and Latin Classical Literature

The Classics List is dedicated to discussion of the Greek and Latin classical literature. The site also provides links to many other sites related to the classics. You can check the archives of past discussions here.

While the focus of this list is the classical literature, and not the language per se, topics related to Greek linguistics are sometimes a part of the discussions.

Inscriptions-L: The Epigraphy List

INSCRIPTIONES-L (formerly EPIGRAPH-L and still often referred to as the “Epigraphy List”) is a moderated discussion list devoted to the study of Classical Epigraphy. While the primary focus of the list is the discussion of inscriptions from the Greek and Roman worlds, discussion of inscriptions from 'peripheral cultures' is also welcome.

The Linguist List Site: Resources for Linguists and Students of Linguistics

The Linguist List site provides access to many resources of interest to linguists and students of linguistics. While it is not directly concerned with Ancient Greek, the topic does come up on the list discussions from time to time and many of the resources available through this site will prove useful for students of Greek who want to broaden their knowledge of linguistics.

Textkit's Greek and Latin Forum

Textkit's Greek and Latin Forum has a section dealing specifically with Greek that covers learning everything from Homeric Greek to the Hellenistic Koine.


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Green Lantern Wiki

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The Older Brother of Hal Jordan.

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  • Jack Jordan

    The eldest Jordan brother, Jack has been voted the D.A. for Coast City, a position that has made...

  • Jack Jordan/Gallery

    Jack Jordan

  • Jordan Family Tree

                                Jessica Jordan Martin Jordan Titus Jordan Jeremiah Jordan Lawrence...

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Carpet Cleaning,
Upholstery & Flood

With a solid experience of more than two decades In the industry, Maxi Carpet Services is a professional carpet and upholstery cleaning company that operates in Wellington, the Kapiti Coast as well as the Hutt Valley regions. We strive to provide the best carpet cleaning Wellington can offer.

In addition to in-depth cleaning services, we also provide a wide array of Wellington upholstery services along with commercial and residential property water damage repair services.

We only work with trained carpet cleaners who use state of the art equipment to make sure your carpets are thoroughly cleaned.

Expert Carpet Cleaning Wellington

Carpet Cleaning is one of our most popular services and you can count on us to ensure your rugs and carpets are professionally cleaned using high-end products and technologies.

Dirty carpets are not only unsightly, but they can also take their toll on your health and the health of your family. Germs, dust and mould that grow in the carpet fibers can lead to a variety of respiratory conditions, or worsen the already existing ones such as asthma.

At Maxi Carpet Services, you will get high-quality, speedy and professional cleaning services for your carpets. We are experts at removing pet odour from carpets and use gentle cleaning products that do not damage your carpets in any way. Maxi Carpet Services offer a thorough deep steam cleaning service that will leave your carpets looking as good as new!

High-Quality Upholstery Cleaning Wellington

Your carpets and rugs are not the only ones that require regular and in-depth cleaning: your upholstery needs that as well. You can now have your lounge suite, your sofa or your mattress cleaned quickly and efficiently, in the privacy of your own home.

Recover from Water Damage Wellington

There is nothing more expensive and annoying than being flooded and realising your carpets, floor or the overall wall structure of your home have been compromised.

At Maxi Carpet Services, you can benefit from professional water damage solutions that will help you minimise the effects of water damage on your home. We are available on a 24/7 basis, and our certified technicians are always ready to promptly respond to your water damage emergency!

Get In Touch With Maxi Carpet Services For A Free Quote!

Whether you are interested in professional carpet cleaning services or prompt water damage solutions such as restoration and drying, you can get a free no obligation quote from Maxi Carpet Services by visiting our website

We offer carpet cleaning services both for commercial and for domestic properties, use only environmentally-safe products and specialise in all types upholstery cleaning jobs.

Contact our friendly team to make a booking!

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Contact Maxi Carpet & Floods

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How I know the hospital census.

My way to work goes through one of our myriad basement areas, the one where empty beds are stored.  I’ve seen literally none, and a lot.

The other night there were so many I couldn’t believe it:

Our count is down. This, too, shall pass.

  1. That’s a good place to look for lost ED gurneys. A sort of bed and gurney swap meet.

  2. Bob Rakov says:

    Same here in our little west Texas hospital. Whereas last weekend, not a bed to be found. Go figure.

  3. Enjoy the quiet time, my friend. Our ER census is a reflection of how many beds are sitting in the hallways during a shift. When I arrive, if the hallways are empty, I run and get a coffee to start my day. If I have to thread around beds, then no coffee for me.

    I hope you have lots of coffee this week! Nice post.

  4. A greater mystery than these spare beds is what happens to the pillows we occasionally have in the ED. They start in ED as precious commodities and then go upstairs with the patient on admission. However, they never come back to the ED. They go off into the great abyss of the admission wards never to be seen again. We must go through thousands of pillows. Is there really a pillow monster on the admission floors that consumes these things? Just one of life’s mysteries, I guess.

  5. nurse 1961 says:

    Beds were used up today and patient’s waited in the ED for more. Over 200 patients in a 12-hour shift. At one point we were waiting for 28 admission beds. The reprieve is over!!

  6. Despite how bad that looks that is actually fairly normal for late night when the transporters clear all the wayward stretchers off the units. It has happened that way for the five years I have been here. Not saying the census isn’t off just that the “runway” in the photo has been used as a temp holding area for a long time.

  7. I noticed it because I walk past it twice a day. Crazy.

  8. Our 62 bed hospital was 25% over capacity this past week. 13 patients boarding in our 14 bed ER; all ER patients seen on hall gurneys. Seems like they came out of nowhere…

  9. I can usually tell how busy the hospital is by who the doctor in the ED is. LOL

  10. nurse 1961 says:

    We can tell how “bad” our day is going to be by looking at which doc is coming in. Two slow docs in a row on a normal day kills the LOS numbers.

    Just a hint: Not everyone needs a “work-up”, we are an ED not the physician office!!!!


text:
mercredi 11 mars 2015

[2015] Australia Virgin LG G3 D850 NCK Code Unlocking to work with Claro,Optus

Australia Virgin LG G3 D850 Overview:

The new LG G3 flagship sports 5.5-inch, 1440 x 2560 (QHD) pixel resolution screen, which provides the super-crisp, 538 pixels per inch. Dimensions are pretty compact for the screen size, resulting in excellent 76.4% screen to body size ratio. The Android 4.4 KitKat-based handset is powered by a quad-core Snapdragon 801 and 3GB of LPDDR3 RAM. It features 32GB of internal storage and a microSD slot. The main 13-megapixel rear shooter comes with the company's improved Optical Image Stabilization+ and has a laser auto focus assist beam, which delivers fast focus even in low light scenarios. The 2.1-megapixel front-facing cam comes with an "enhanced selfie mode".

Unlock Australia Virgin LG G3 D850

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You can request the code by submitting your imei

Your phone will also keep working with your current lock to service provider.

Take Your
Australia Virgin LG G3 D850with you on vacations and use the local service provider sim card in your phone and save roaming fees.

Australia Virgin LG G3 D850 Unlocking Instructions

1: Turn on phone with Not Accepted SIM card.

2: A menu will pop up to Insert the code.

3: Insert the provided code and press OK

4: Device is now unlocked.

After Unlocking Australia Virgin LG G3 D850 will work with

Also any where in the world with any Supported Carrier

*Supported carriers can vary based on your locked to carrier and your region, please confirm with your service provider, before placing order

Your phone will be permanently Unlocked,it will not erase your contacts or any data from your phone.

Reasons to remote unlock your Australia Virgin LG G3 D850:

* If you are travelling, buy a local SIM card and save on roaming fees

* The resell value of Australia Virgin LG G3 D850 will increase significantly as it is available to more carriers.

* Easily switch between SIM card, using the same phone.

* Unlock your phone from the comfort of your own home

* You never send your phone to anybody.

* There is absolutely no risk of damaging your Australia Virgin LG G3 D850 by unlocking it.

* Very easy, no technical experience necessary.

* The phone is permanently unlocked, even after updates

* Warranty will not be voided by this Code

* 100% Guaranteed, if we cannot get you your unlock code we will refund you no questions asked.

via Welcome to gsm-tips

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    Christopher Edward Martin, better known as DJ Premier, (born on March 21, 1966 in Houston...

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This is a screenshot of Grand Theft Auto V - a copyrighted video game by Rockstar Games.

On GTA Wiki, it is believed that the use of web-resolution screenshots, for identification and critical commentary on the game in question or the copyrighted characters or items depicted on the screenshot, qualifies as fair use under Copyright law, as such display does not significantly impede the right of the copyright holder to sell the copyrighted material, is not being used to generate profit in this context, and presents ideas that cannot be exhibited otherwise. To re-use this image, you must link back to this page.

See GTA Wiki:Copyright for more detail on our copyright policy.

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    Chopper Killer is Rockstar verified air race featured in Grand Theft Auto Online. It is...

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GTA Wiki

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"Francis" redirects here. For the airport in GTA III, see Francis International Airport, Shoreside Vale. For the airport in GTA IV, see Francis International Airport, Dukes.
"There's no good and no evil... just shades of fucking grey."
―Francis McReary

Francis "Frankie" McReary (Irish: Proinsias Mac Ruairí) is a character in the Grand Theft Auto series who appears as a main character in Grand Theft Auto IV.

Francis is the corrupt Deputy Police Commissioner, and the second-oldest son of the McReary Family. He works at the Westminster Police Station in Westminster, Algonquin.

Francis is the brother of Patrick McReary, Derrick McReary, and Gerald McReary. He is the second -oldest child of the McReary family if his only sister Kate, is included.

Francis and his brothers grew up in an Irish Catholic home. He is frowned upon by his brothers, who consider him a hypocrite for his career in Law Enforcement; Patrick McReary remarks that "Francis is just as crooked as we are — moreso"; Francis gives his brothers similar disdain for their open criminality. He initially wanted to become a priest, but as his brother Patrick recalls, he had to abandon that ambition after being caught cheating on his final test to be a priest; he also had a selfish tendency to steal money from the church donation plate as an altar boy.

Francis tells Niko that his philosophy to cleaning up the streets of Liberty City is "one percent at a time" — assassinate small-time crooks and drug dealers one by one, to "improve" the city without involving the legal system. This may be mere self-justification on Francis' part — the tasks he sets for Niko are overwhelmingly focused on covering up his own misdeeds. Francis is implied to have illicit tastes, which go unspecified but which may be related to drugs and/or prostitution, as he orders the assassination of a drug-dealing pimp who is implied to be personally inconveniencing him.

It seems he has the same philosophy as Frank Tenpenny, thinking if a necessary number of people do like he does, the community would improve.

Events of Grand Theft Auto IV

Francis first meets Niko Bellic during a publicity spot with Manny Escuela. Later in the game, he calls Niko and arranges a meeting at Castle Gardens, where he reveals that he knows of Niko's criminal activity in Liberty City; Niko agrees to work for Francis in exchange for his turning a blind eye to Niko's other crimes.

Francis first orders the death of a blackmailer who possesses incriminating photographs, and then the death of Tom Goldberg, a lawyer who has evidence against Francis. He has Niko kill a drug-dealer and pimp in the East Holland projects, and then the dealer's accomplice, who is threatening to talk to the police about McReary.

Blood Brothers

After Francis' brother Derrick returns from Ireland, Derrick intends to expose Francis' corruption out of spite, something Francis could not accept as he aspires to become the Commissioner of the LCPD. He orders Niko to kill Derrick during a meeting he has arranged with his brother. Niko either chooses to follow Francis' orders, or goes against them and spares Derrick's life by killing Francis instead. Either choice will end Niko's career with Francis, although Niko can choose to exploit Francis' guilt in the future if he survives. Killing Derrick also allows the player to gain ability of using Francis to remove any wanted level against him for the duration of the story. If assassinated during the mission Blood Brothers, he is then buried at the Colony Island cemetery.

Mission Appearances

Wanted level reduction

If Francis' life spared in Blood Brothers, the player can call him and have any wanted level they have cleared by him. Although this can be done multiple times, the wait required between calls is undetermined — calling too soon after the last successful call will merely redirect to Francis' answering machine. Once the player finishes the story missions, Francis' ability will not be available anymore because most contacts, him included, on Niko's cell phone are deleted at the end of the game.

  • Francis McReary appears to be based on Hector Cruz, a character in the film "Entrapment" played by Will Patton. Both characters work for law enforcement and share the same moustache.
  • If Niko kills Francis, his gravestone in Colony Island reads: "Here Lies Francis McReary, Brave, Honest, Shot Dead." Derrick's gravestone will say the same thing if he is killed, but his grave will be in Steinway.
  • Francis drives a black Landstalker, seen in the opening cutscene of Blood Brothers.
  • As Francis is an LCPD officer, he has no record on the LCPD police database.
  • If Niko kills Francis, in the mission I'll Take Her..., Gerald McReary says that he and Francis were never really close, but that "I'll miss him."
  • He appears to be very hypocritical throughout Grand Theft Auto IV; he speaks freqently of second chances or chances at redemption, but he orders Niko to kill Clarence Little because "He is guilty as sin."
  • Sometimes, if Niko starts getting chased by the police while on friendship activities with Packie, he will often shout "Look, Frankie's boys!".
  • Francis can be seen on the homepage for
  • In Blood Brothers, Niko can call Francis once to increase his payout, to $20,000, if he kills Derrick.
  • Francis is the first member of the McReary family Niko meets and works for.
  • Blood Brothers is the only time in the game when Francis appears outside of cutscenes.
  • Although his rank is given as "Deputy Police Commissioner" it is likely that he is in fact the First Deputy Commissioner which is the rank below Commissioner in New York (and most likely Liberty City) Police Department. It is also quite possible that he is (or was originally intended to be) the Chief of Police since both Niko and the officer behind the desk in the cutscene for Final Interview refer to him as such. One thing to note is that in New York, the role of Police Commissioner is a ceremonial post and the holder is elected by the mayor i.e. not necessarily a police officer, whereas the Chief is a serving member of the Department who has worked his way up through the ranks over time.
  • Due to the fact he originally wanted to become a priest and Derrick's reference to Cain and Abel in "Blood Brothers" Francis may represent Cain. This is supported by the fact that his other brothers hate him, and Kate referenced looking up to Derrick and his other brothers respecting him, as well as the fact that it was Francis who first asked Niko to kill Derrick. However also due to the fact he is the only police officer in a family a criminals and Francis telling his mother "He has always been a good boy", he may also represent Abel, if a heavily deconstructed version.

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Guardian Life Guardian TV Facebook Instagram Twitter

China’s third-quarter growth falls to 6.6%

By AFP   |   17 October 2016   |   12:09 pm

China’s growth slipped to a seven-year low of 6.6 percent in the third quarter, according to an AFP survey, despite ample stimulus and a red-hot property market in the world’s second-largest economy.

The median forecast for expansion in gross domestic product (GDP), based on a poll of 18 economists, represents an easing from the second quarter’s 6.7 percent.

It would be the slowest quarterly growth since the first three months of 2009, in the middle of the global financial crisis.

As the world’s biggest trader in goods China is crucial to the global economy and its performance affects partners from Australia to Zambia.

GDP expanded 6.9 percent in 2015 — its weakest in a quarter of a century — and the government has targeted growth in a range of 6.5-7.0 percent for this year.

The AFP poll forecast China will just meet the goal, with the median full-year prediction at 6.6 percent.

“Our expectation is that growth will continue to slow. The largest headwind on the horizon is the housing sector, which peaked in April 2016 and thus is now in the correction phase of its cycle,” Brian Jackson of IHS told AFP.

Beijing is trying to execute a difficult structural transition away from dependence on low-end exports and heavy industry toward consumption and services, but entrenched interests have slowed progress.

At the same time, authorities have sought to combat a slowdown through hefty fiscal stimulus and loose home-buying policies that have fuelled property market booms in urban areas.

“Economic growth in the third quarter was better than market expectations,” Rong Jing, a Beijing-based analyst with BNP Paribas, told AFP, but pointed to possible risks arising from the real-estate boom.

“The property bubble risk will continue to balloon if the government does not take tightening measures, as it would cause a very negative impact on the economy and the financial system,” she added.

“The biggest restraint this year that prevents monetary easing is the real estate market.”

In recent weeks lawmakers have unveiled tighter home-buying regulations in major cities to cool down galloping property prices.

– Mixed signals –
Recent indicators have painted a mixed picture of China’s economic health.

An official measure of manufacturing activity maintained its strongest level in nearly two years in September while auto sales grew at their fastest rate in three years in the world’s biggest car market.

Data Friday showed that the price of goods at the factory gate rose in China for the first time in more than four years in September, a positive sign for demand after years of dropping prices battered manufacturers and put a damper on growth.

“Recent economic data suggest that China’s growth momentum has stabilised,” said Raymond Yeung, an economist with ANZ. He pointed to recovery in private investment after “a period of massive decline”.

But exports sank 10.0 percent year-on-year in September, suggesting the Asian giant is yet to see the bottom of its years-long growth slowdown.

Imports returned to negative territory last month after a brief rise in August, with iron ore and copper volumes dropping, leading analysts to warn that the recent recovery in manufacturing activity could be short-lived.

Looking ahead, GDP growth faces the “downward pressure of a coming housing downturn, in particular in the first half of 2017” said Claire Huang of Societe Generale.

Zhao Yang of Nomura expected China’s yuan currency to be “much weaker” and forecast slower growth in the fourth quarter “due to the cooling down property market and waning demand from post-flood reconstruction”.

But Mizuho economist Shen Jianguang said that China’s growth this year could be “stronger than the official data suggests”, in contrast to last year when official figures probably overstated true expansion, he added.

Official Chinese figures are viewed with widespread scepticism, and in July the government altered its growth calculation method for the second time in less than a year.

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Eavesdropping In: The Real Easter Bunny, Georgina Bloomberg Models, Ian Reitman's Hilton Deal

by SUSANNAH LONG · April 5, 2010

The Snopes.Com fact-lovers hate us and our kind. [Times]

Easter Bunny on a leash makes us want to be reincarnated as bunnies so we can have bunny babies. [Gothamist]

Mayor Bloomberg's baby girl Georgina signs with Wilhelmina. [Page Six]

Devi's ex-owner reopens a gingerbread cottage of barbecue in Times Square [Eater]

Bottle Girls are the new town hussies. Tiger Woods is involved. Obvi. [NYMag]

Ian Reitman crawled into bed with Hilton Hotels to get "Up In The Air" made. We wish we could replace "Hilton Hotels" with "George Clooney" in this sentence. Alack! [NYMag]


text:
Moving Guide

How to Pack Books

Most of us don’t give books any special consideration while moving them. Whether you are moving old textbooks, paperback novels or a prized collection of first editions, properly packing your books will prolong their shelf life and prevent damage.

Supplies needed: Packing books is relatively easy and takes very few resources; all you need are small boxes, blank newsprint and packing tape. The boxes should be small as paper is very heavy and large boxes filled with books would be very difficult to move.

  1. Prepare a small, sturdy box by double taping the bottom.
  2. You can pack the books one of three ways, depending on the size of the book and the box. You can pack them straight up (like on a library shelf), on their side, or with their spines down. If you are packing them on their side, you want to pack the largest books on the bottom, and the smallest on top. Any combination of these directions will work; the idea is to pack a small box as full as possible and prevent the books from shifting around and being damaged during the move.
  3. Fill any extra space with crumpled blank newsprint. Slightly overfilling the box with newsprint is preferable to leaving room for the books to shift during transport.
  4. Make sure the box weighs around 30 pounds. Seal and mark box.
  5. For prized books that you want to maintain in excellent condition, wrap every book individually with packing paper. If your books are bound in paper or a limp binding (i.e. leather-bound books), reinforce the covers with colorless cardboard before wrapping them.
  6. Once the books are boxed and sealed, do not to leave the box on the floor, as moisture and condensation can damage the books.
  7. Avoid filling empty space in the boxes with any loose items that could potentially damage the books.
uShip Movers

How to Pack & Move Your Computer

Your computer needs special care during the moving process. Not only is computer hardware valuable, but data is often irreplaceable. Computers are delicate electronic devices and you should make sure that they are safely packed, and your important files are backed up. If you have a laptop, just put it in your regular laptop carrying case and take it with you in the car during your move. Otherwise, follow the steps below to ensure safe delivery of your computer.

1. Back It Up

The data that you have on your computer can often be of more value than the computer itself. Protect your financial records, family photos, music collections and the countless other files on your computer by making a backup of your important data before your move. If you have a DVD-R or CD-R drive with the ability to “burn” data (save data to a blank disc), you can make copies of all your files. If you don’t have a recordable disc drive, then you should consider a USB memory drive. They are cheap, safe and can store quite a bit of data. You also have the option of an external hard drive, which can store huge amounts of data and back your computer up completely.

When backing up your files, don’t forget:

  • Documents, spreadsheets, and presentations
  • Pictures
  • Music files
  • System settings, like favorite websites
  • Emails
  • Financial records
  • Saved passwords

2. Disconnect the Cables

Once you are done backing up your files, shut off your computer, monitor and any peripherals and disconnect all the cables, starting with power cables. If you’re not very familiar with setting up a computer, make sure you label the cables as you disconnect them. “Twisty ties” or Velcro ties are really useful for keeping cables organized. Store all the cords in a separate box than your computer and don’t forget to wrap your keyboard, mouse and other components before packing them away.

3. Wrap it, Pack it and Seal it

Once your data is backed up and your cables safely stored away, it’s time to pack your computer. The best option is to use the original packaging or purchase a computer packing kit complete with padding at any moving supply store.

Pack your computer upright, or with the motherboard side down. You want to make sure that the box is padded well enough so the computer is snug in the box. Protect your computer by wrapping it in bubble wrap and filling empty space with padding such as packing peanuts or paper so it doesn’t take damage on the road.

Your monitor should receive equal care. Protect the screen with padding and ensure the box is not too large. For the older CRT monitors, pack them with the screen side down, properly cushioned with bubble wrap or packing paper. For flat screen monitors, you can pack them much like packing a mirror. If you can’t get a specialty box, make sure that the bottom is sturdy and well cushioned to protect it from damage.

Keyboards, mice and cables should go in the same box as your computer if there is room. For multiple computers, make sure to pack each computer’s peripherals in their respective boxes. Mark all boxes with computer equipment as “FRAGILE” along with the room in your new house they belong in.

4. That’s a Wrap!

With your computer safely packed away, the only thing left is to put it back together when you arrive. As a safety precaution, you will want to plug your power cable in last. Once your computer is up and running, do a quick check to make sure everything is working correctly and you haven’t lost any data.


text:
The Tea Parties and the Jealous Power and Money

Kelleigh Nelson’s Tea Party series, parts 1 & 2 Parts 3 & 4: “The Tea Parties: Organizers & Operators“ scrutinizes the professional movers, shakers, shepherds, and gatekeepers of nationwide Tea Party enterprises. ------GB------ July 29, 2011, 11:05 am CT "It is a known fact that the policies of the government today, whether Republican or Democrat  are closer to the 1932 platform of the Communist … [Read more...]


text:
National Reciprocity Bill Will Apply to Non-Resident Gun Carry Permits (This is nuclear)

January 11, 2017 5:52 pm
Rep. Richard Hudson (R., N.C.) clarified on Wednesday that his national concealed carry reciprocity bill would apply to permits issued by states to non-residents. After Hudson introduced the Concealed Carry Reciprocity Act of 2017 last week, questions were raised about whether it would apply to permits issued by some states to non-residents. In an interview with the Free Beacon, Hudson confirmed that permits issued by any state to residents or non-residents would have to be recognized by all other states under his legislation.
“My legislative intent is to ensure a non-resident carry permit is recognized, and I’ve confirmed this with legislative counsel and Judiciary Committee staff,” Hudson said.

Source: National Reciprocity Bill Will Apply to Non-Resident Gun Carry Permits

This is not only nuclear but terraforming. If passed, all the efforts by Michael Bloomberg to keep New York City “under control” (read, depending o the graces of the authority) will become sand in a hurricane. Same for Chicago and selected locations in California. Citizens of those places can get a CWP from Florida or Utah or wherever they issue out-of-state licenses and be able to defend themselves.

I am sure that the respective states will throw in some wrenches such as firearms identification cards like in Illinois and maybe some other restrictions that will need to be fought at state legislature and court level. But they Opposition does not have the impulse for that it once had.

Now, don’t get mad if the Non-Resident reciprocity gets tossed out and we get Plain Jane Reciprocity. Sometimes deals need to be made and we cannot let Perfect be the enemy of Damned Good. But keep fingers crossed for it anyway as it could be the crack in the dam for those Freedom-less states.

Owner/Operator of this Blog. Pamphleteer De Lux. I lived in a Gun Control Paradise: It sucked and got people killed. I do believe that Freedom scares the political elites.

  1. There will still be legal traps that are designed to ensnare legal carriers. Have hollow points in your firearm? Felony. Have a regular capacity mag? Felony. Carrying a gun with a red dot unless it’s on a full moon and the 4th Sunday in February? Felony.

    Unfortunately, national reciprocity will be the start of a different kind of legal war.

    • Just let me carry in NJ. At this point, something is better than nothing. Getting our camel’s nose under their tent for once would be a fantastic thing.

  2. Take your victories where you can find them and fight the abuses as and where they occur.

  3. With all due respect — and thanks, don’t get me wrong — to Rep. Hudson, where in the bill does it explicitly say that non-resident permits must also be recognized?

    Should the bill become law, and when it is challenged in court by anti-gun states, the first and foremost thing the courts will consider is what the law says. “Legislative intent” will be a factor, but a small one compared to the plain-text language. As we all should know by now, intent is not transferable.

    If I were to bring a bill and my honest-to-God intent is to preserve public land access to ensure hunters can continue enjoying their pastime, but a line in my bill says that while the land is accessible, hunting is banned on it within the borders of my state, it doesn’t matter one iota what my intent was; the language overrides it.

    If his intent is to make non-resident permits equally valid for the purposes of national reciprocity, I will want to see language in the bill clearly expressing that.

    And yes, I know we may lose that portion but keep general national reciprocity (for resident permits only). It would still be a good bill and worth passing into law. My point is only that his intent can and will get thrown out the window if legislated push comes to litigated shove, so to me it’s an empty promise.

  4. I think the most important part of carry reciprocity is getting people with permits into the states where legal carry has been effectively banned. The citizens of these states will realize that they do not cause, “OMG! Blood in the Streets! Wild West Shootouts!” and all the other gun control lies we have heard.

    Permitted Carry passed in Minnesota and all the dire consequences never happened. A few years later, it passed in Wisconsin, and the streets again did not run red with blood.

    When the citizens of NJ, Maryland and DC see that people with permits are not trouble, they will be able to change their own state laws. They will regain their rights again, Step by step, the same way we lost them, and then regained them.

  5. Imagine the consternation in NYC if the NRA Convention is held in Manhattan and 50,000 people are carrying. Imagine the shock, when the biggest story is All Those Evil Guns, and Nothing Happened!

Feel free to express your opinions. Trolling, overly cussing and Internet Commandos will not be tolerated .

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Katherine Bryan Hoover, age 25

Lost to gun violence on July 26, 2014 in Brooksville, Florida.

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    1 Ridgewood High School
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text:
William Valdez, age 69

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Lost to gun violence on August 31, 2015 in San Angelo, Texas.

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Want to say more about William or about how gun violence has affected your life?

This January we will release a video about gun violence and we would like to include messages from people like you. To leave your message just call 📞 (773) 453-5556 and press 2.

Other nearby fatal shootings:

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