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Editorial: Admin disappoints with proposed parking plan

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On Sept. 4, an email was sent out to the Redwood community by Principal David Sondheim outlining the draft of newly proposed parking restrictions for the 2018-2019 school year. The new measures are being considered to mitigate problems with “safety,

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environmental impact/resource use, commute traffic congestion and student, parent and community impact,” according to Sondheim’s email. A survey was issued to students and parents to obtain feedback about this proposal; however, it will only be viewed and considered by Sondheim and Assistant Vice Principal Saum Zargar before a final draft is made. A mere three days were given to submit responses, but it is unclear whether this feedback will create discernible change to the policy.

The proposed changes include limiting the number of permits to the number of spaces available, assigned parking spots with “carpools given highest priority and long distances from school being given the next highest priority,” according to the email. The draft also prohibits all students in the school parking lot from driving their cars off campus at lunch and break.

The proposal has, rightfully, been met with outrage by the student body and members of the community. The administration’s proposed parking plan is inefficient, disregards the individual needs of students and largely fails to take student opinion into account.

Past parking policy has accepted all applications from upperclassmen, with this privilege extending to sophomores as of the 2016-2017 school year, creating a high demand for parking. Although this system was less than ideal, the proposed draft takes us from one end of the extreme to the other, with far too many restrictions.

One of the most protested changes is the assigned spots, which is an asinine attempt to monitor students’ parking at an excessive level of detail. The major flaws with this are two-fold.

The enforcement of such assignments will fall on campus security officers, who are tasked with ensuring student safety, not monitoring individual parking spots. Additionally, when assigned spots are empty due to absences, administration has said they will be given to visitors or substitutes, but not other students. Saving spaces for hypothetical needs defeats the purpose of finding a lasting solution to the problem for all involved, especially given our limited amount of parking spots.

Two criteria (carpooling and distance from school) for prioritization of permits given have been proposed, both of which are inconsiderate of student and community circumstances. Carpooling demands regularity in student schedules, which is rare; after-school jobs, sports, family obligations and excused absences require flexibility in transportation options. While the policy is meant to encourage carpooling, there are significant irrationalities that render it counterproductive.

Distance prioritization is another major issue with this proposal. Such priority would allow students living in areas such as Belvedere-Tiburon a greater chance of receiving a permit, despite their access to chartered Marin Transit buses. For students who live in areas such as Greenbrae or Corte Madera, there is an insufficient bus system to transport them to and from school, bringing into question the equity of student transportation. Although these areas are closer to school, walking to school is impractical as even two miles could take at least 40 minutes, nullifying the reasoning for the distance qualifier.

Not only is this proposal an inefficient use of our paid administration, as they will have to sift through complex details regarding distance and carpooling before issuing permits, but it is also a careless use of our monetary and spacial resources.

The most effective solution would be to issue as many parking permits as are requested within a designated time frame in the fall, which would lower the estimated 800 requested permits and allow a first-come-first-serve system, which has worked in the past. With this process, absences would not leave open spots, and students who need parking on any given day can fill them.

Administration believes that the entirety of the consequences of the proposed parking changes cannot be gauged until the changes are made. Unintended and unpredictable repercussions are inevitable with such an extreme strategy. Instead of overcompensating for the lax parking plan of past years, a better strategy is to start with a less drastic measure, such as simply limiting time for applications, and observe whether this alone will be sufficient to improve the situation. If there is enough evidence that the initial measures are ineffective, then administration would be justified in enforcing additional restrictions, such as assigning parking spaces.

Last year’s parking situation wasn’t optimal by any standards; there is no ideal solution for the parking problem simply because of the disparity between the number of people who want to park on campus and the space available. However, restricting our parking to this extent is not just logically flawed, but also sends a message that student and community voice are not adequately considered in school-wide decision making.


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My little girl Nina

I finely finished the outfit for my little girl Nina, just before the LDoll Festival 2016 in Lyon, France.

I am happy with the result 🙂 She turned out very ‘frenchy’, so to say 😉

I really hope she will find a loving home, though, as usual, I love her, as all my girls, so much..

Porcelain Beauty LILY in my Etsy shop looking for a loving home

My new porcelain ball-jointed doll NINA, looking for a new home in my Etsy shop

Commissioned Doll MARIA2

want to show today photos of my first commissioned doll. This is Maria2-porcelain ball-jointed doll. I gave her blue glass eyes of superior quality, hand-crafted in Germany.

It was a very valuable experience for me to work on a doll in certain time frames and under obligations. It was not always easy and smooth.. considering the unpredictable character of such a material as porcelain. But in the end, I think, she turned out a beauty 🙂 Love her Love her!!

The girl is already in her new home in Germany. I hope she will bring lots of joy to her very nice owner 🙂

My Porcelain BJD LISA is on Ebay Tonight!

Hello everyone!

My beloved porcelain ball jointed doll LISA is on Ebay tonight!

The auction will last for 5 days and end on Saturday 2.07.16.

And here is the Ebay link:

I hope my girl will soon find a new loving home 🙂 She is very beautiful and I love her sooo much!

More photos of Lisa can be found on my Flickr account.

Any questions? You are welcomed anytime!

Have a nice week 🙂

Max-Oscar-Arnold-Award for Contemporary Art Dolls

It is almost a month ago.. and I could not find a time to tell about such an important thing, that happened to me in Nuestadt bei Coburg, Germany. At the beginning of May I won a Max-Oscar-Arnold-Award for a Contemporary Art Dolls of the Bavarian Dolls City Neustadt bei Coburg :))

It is such an honor and SUCH a BIG push for me in my new passion and career as a doll artist. Again, a BIG Thank you for my family for supporting me on the way. I love you!!!

Here are some photos of the other participants and winners of the award. Wonderful art!

My doll Red Riding Hood was also presented in the category “Fantasy Dolls”.

Stay tuned 🙂

SpringDollFestival in Münster 2016

it is been a WHILE since I came back from two doll exhibitions in Germany.  And only now I think I can scrap a little time to tell you about it 🙂

It was my first time and first attempt to take part in such events…and let me tell you…IT WAS GREAT!!!!!

But first things first. In this post I’ll tell you about Spring Doll Festival in Muenster, Germany. Next post will be devoted to my participation in the Max-Oscar-Arnold-Award for Contemporary Doll Art in the city of Neustadt bei Coburg 🙂

The Spring Doll Festival was an event 2 in 1 so to say: an exhibition/salesroom and a doll contest for an award AMALIA, organized by a Puppen&Spielzeug doll magazine.

The contest theme was Flower Power. I am so happy that my doll received one of AMALIA awards :))!!

Hier is my table with the dolls..

You could see all kinds of dolls and toys at the exhibition. It was a wonderful experience for me. I have met so many talented artists, some of them I knew from social medias like Instagram and wanted to meet them in person for a long time 🙂

like a wonderful doll artist Anna Linberger – GCDoll

or Marina Demchenko..

or Viktoria Fribus..

And there was a magnificent Hildegard Günzel! I have been admiring her magical dolls for such a long time, having all her books and never even thinking about meeting the artist someday.. Well .. it happened in Münster 🙂 And Frau Günzel and her art dolls are more then you can imaging looking at the book photos! One of the nicest and positive persons I have ever met.. She is just GREAT! I am solo grateful for this experience ..

And here is Frau Günzel with my porcelain doll Lisa! :)) I can not believe myself that it happened!!

The two days in Münster were really full of experience and super interesting meetings with the visitors and great coming-together with the other doll artists.

I can not post here all the photos I’ve made of all kinds of dolls presented there. I will probably do it on my Flickr account, if you are interested 😉

I would like to finish for today with this photo..Like it so much!

People like dolls, dolls like people 🙂

Me with my little Tiger and Anna Linberger- Gentle Creation Doll meeting Cosplay People (I think this is the right word 😉

Stay tuned 🙂

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Home Decorating Ideas

Choosing Kitchen Worktops Designs

Diy Concrete Kitchen Worktops Ideas For Kitchen Freestanding Islands Tables Design In Kitchen With Tiles Flooring
There are pros and cons to all kitchen worktops design which can be divide into several options such as laminate kitchen worktops, granite kitchen worktops and wooden kitchen worktops. This is also an essential part when renovating or building a kitchen. Kitchens are the important part of a home and it is probably the most utilized space of a house. Choosing the perfect kitchen worktops is one of the important elements to consider. Advantages of Wooden Kitchen Worktops : Wood will always be a much-loved material. It looks beautiful and is available in so many variants. The sanding and finishing thereof is quite important. It can work well in traditional homes and modern homes. It is a pricey option but some might consider it a worthy investment. If you are running a tight budget you may want to consider buying an inexpensive common wood and staining it by technique to look luxurious. It is worth taking into account that wood will always require maintenance. Advantages of Granite Kitchen Worktops : Kitchen worktops granite are durable and long lasting. They are aesthetic modern and there are various types available. Scratches may occur but can be buffed out. Granite countertops are quite expensive and should be fitted professionally as it requires extra structure support. Other advantages include heat resistance, which increases the value of your home and it does not depreciate in value. It is also easy to clean. It should not be mistaken that granite top cannot be cracked or chipped. This is possible. Advantages of Laminate Kitchen Worktops : Kitchen laminate worktops are by far the most effective kitchen worktop. There are numerous designs and colors available. It is also hardwearing if it is a high quality laminate. The designs can be made to imitate different types of wood or can even resemble granite countertops. It is also easy to change the design as should you grow tired of your existing laminate kitchen worktops. It is after all the cheapest option available. 3 Tips on Choosing the Best Kitchen Worktop
  • Work out a budget so that you know which options you are working with.
  • The choice of your kitchen worktop should compliment your cupboard and will therefore also be a deciding factor.
  • If you have a small kitchen design a space efficient kitchen and choose materials that can easily be manipulated to save space.
Kitchen worktops either laminate kitchen worktops, granite or wooden tops alike have their own advantages. And it is recommended that you familiarize yourself with relevant information to ensure you make the best choice for your new kitchen remodeling ideas. The White Painted Solid Wood Kitchen Worktops Ideas For Contemporary Kitchen Design With Plank Flooring Options 150x150.jpg is segment of Choosing Kitchen Worktops Designs has dimension pixel. You can download and obtain the White Painted Solid Wood Kitchen Worktops Ideas For Contemporary Kitchen Design With Plank Flooring Options 150x150.jpg by click the images above to get multiple high resolution versions. Here is important information about Kitchen Designs.

Gallery of Choosing Kitchen Worktops Designs

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Kingdom Prologue: Genesis Foundations for a Covenantal Worldview

Publisher’s Description

As intimated by the subtitle, ‘Genesis Foundations for a Covenantal Worldview’, the immediate literary focus of this study is the book of Genesis and its account of the formative ages in the eschatological movement of the kingdom of God from creation to consummation. As also indicated by the subtitle, our biblical-theological commentary on Genesis is designed to uncover the foundations of God’s covenantally administered kingdom with its major historical developments and its institutional structures and functions. In this way ‘Kingdom Prologue’ seeks to provide an introductory sketch of the overall shape of the biblical worldview and the character of biblical religion.

Images of the Spirit

Publisher’s Description

The underlying concept developed here is the paradigmatic function of the theophanic Glory-cloud in the creation of the image of God. Dr. Kline identifies the major symbolic models employed in Scripture to expound the nature of the divine image in humanity – the priestly and the prophetic.

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Copyright © 2020 Reformed Forum


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New “IT” Images

The big screen adaptation of Stephen King’s novel “IT” is less then two weeks away from hitting theaters and a new set of high-resolution images reveals terrified kids from The Losers’ Club.

New “It” Teaser

The new Wonder Woman trailer wasn’t the only movie to have new material debut during Sunday nights MTV Movie Awards, New Line Cinema’s “It” saw a new teaser drop.

Jason's Movie Blog

A Movie Blog for the Latest Movie Reviews, Trailers, and More

Movies, Podcast, Posters, Blu-ray's/DVD's, Television, Humor

Hammy Reviews

Reviews of Films, TV Shows, WWE and more...

film reviews, etc.

Tony's Domain

A collection of fiction, art & musings by Tony Wilkins

Movies, thoughts, thoughts about movies.


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In Meghan Markle’s Footsteps!

LOCATION: Capetown, South Africa

WEATHER: Super! High 70. Sunny

Today we were 100% tourists – pounding the streets of Capetown and seeing its highlights.

Some friends had recommended the District Six Museum, so we checked it out. Here we are looking at the stories behind the 60,000 people that were removed from their houses in District Six during Apartheid…

Oops – wrong couple – Meghan and Prince Harry, not Karmen and George. They were here a few weeks ago.

It is a very interesting (and sad) museum. Actually an old church, it tells the stories of these people. Coincidentally, our cab driver told us he was born there, and his story was the same — that it was a delightful neighborhood full of diversity (everything imaginable except pure whites). Then, the whites bulldozed the area and resettled the residents in townships.

The Apartheid government imposed strict rules on where the non-Whites could walk, work, go to school, and shop. They had to carry cards that identified their race, and could be imprisoned for not carrying their cards or for violating the stipulations.

They were mostly divided between “black” (Bantu) and coloreds (everything else – mostly mixed, or Indian, Muslim, or Middle East). Coloreds were treated better, so some blacks tried to pass for colored. The government did a pencil test…..If the pencil stuck in one’s curly hair, you are black. If the pencil falls out, you are colored. If you are bald, the upper lip and nostrils were measured to make the decision. Wow!

Somehow, I don’t think Prince Harry and Megan Markle used the transportation we did – the Hop On Hop Off Bus…

It is really a deal at $30 for 3 days, with various routes all over the city and cape. It took us next to the cable car that goes up Table Mountain…

The cabin rotates 360 degrees while you are traveling up to the peak.

The views from the top are magnificent…

(not a very photogenic photo, but you get the idea….)

While we were there, the famous fog drifted in…

Some people climbed it!

Then, back on the bus to downtown. Many of the buildings still have their colonial facades.

On a different Hop On/Off bus, we drove through the touristy beach area. It is filled with elegant homes, high rises, classy shops and sidewalk cafes.

On our way home, we stopped at a grocery store to stock up again. George bought three kinds of billtong (jerky) in a deli case just for this popular food. He bought 3 kinds – game, ostrich, and kudu. A great snack, and not too expensive.

DINNER: Yeah! The BBQ grill (called braii here) works. The rooftop on the apartment has a nice, large BBQ area, and all 6 grills were busy tonight.

He grilled a pork steak and some veg (baby cabbage, onions, and bell peppers). Side was rocket (arugula) salad.

We were really pooped after a long day being a tourist!

Not imprisoned on Robben Island

LOCATION: Capetown, South Africa

WEATHER: Perfect! High 70 and sunny

Today’s highlight was a visit to Robben Island, where Nelson Mandela was in prison for 27 years. The island is a UNESCO world heritage site.

After a 30-minute ferry ride, we were escorted by bus to the prison area. Our guide is a former prisoner, there with Nelson Mandela. He was very stern.

The guide was very informative, and we learned that there both criminal as well as political prisoners there during his stay. Conditions were terrible – in this area 40-60 inmates slept on the cold hard floor.

At some point, the rest of the world learned about these prisoners, inspected the prison, and got conditions improved a bit, to include actual cots.

There were no white prisoners, but there was still differentiated treatment based on skin color – Blacks (called Bantu), coloreds, and asiastic. They were placed in different buildings and were given different types/amounts of food.

This is Mandela’s cell…

Then, we took a bus ride around the island. About 300 people still live in the little town where the wardens and military stayed when the prisoners were there. We stopped at the tip of the island where we could see Capetown across the water. There were huge clumps of seaweed in the water.

The island has had a long history of sadness. It was used as a prison back to the 1600s. Then, it was a dumping ground for people with mental illness and leprosy. This leper graveyard reminds us of that era…

Back on the mainland, this seal greeted us….

It was a very interesting outing We are glad we did it.

DINNER: Ostrich burgers!

They tasted more like beef than poultry.

First impressions of Capetown

LOCATION: Capetown, South Africa
WEATHER: Just perfect. Sunny. High 70

As we docked in the harbor, we enjoyed beautiful views of Table Mountain (appropriately named) that looms over the city.

We disembarked at about 10:00. There were LOTS of suitcases waiting for people to pick up. Our tiny rollerbag looked a little sad among all the huge cases. Just glad we don’t have to lug them around!

As we disembarked, this local gospel choir greeted us with dancing and singing.

We made our way to the very nice Air B&B apartment where we will stay for a week in Capetown. The apartment is very modern. We have views of the waterfront as well as Table Mountain from either side.

So far, it seems like a lovely city. We strolled through the V&A (Victoria and Albert) Waterfront which is full of shops, outdoor restaurants, and tourist attractions.

DINNER: We found a supermarket not far from our apartment and bought food for a few days. We will probably eat breakfast and dinners here, and eat lunch out. To our delight, we found gas BBQs on the rooftop deck, so bought food to grill.

Uh-oh….when we got ready to grill the chicken wings for tonight’s dinner, we could not get the grills to work. So, I improvised and sauteed the wings in a skillet inside. I added diced bell peppers, mushrooms, and onions. At the end, I added white wine and plain yogurt for a sauce. Not too shabby. Served with a salad. It is nice to be able to cook again.

Speaking of wine…..the South African wine is excellent so far, and quite cheap (especially compared to the cruise ship). We bought medium-priced bottles for $5 at the grocery store. $2 a glass in a cafe where we had lunch. I will like this!

The delightful cruise ends….

LOCATION: Last day on the Queen Elizabeth. Docked in Capetown, South Africa
WEATHER: Mild, high 70

We departed from Walvis Bay, watching huge jellyfish swim next to the ship in the harbor. We learned that only about 6 cruise ships dock here a year, so it hasn’t become very commercialized yet.

The seas almost immediately became rough. We just have one more day at sea before we reach Capetown. Many of the passengers are going on to Australia from here— 3 more weeks!

We tried to take advantage of the ship’s offerings one more time before we go….

A glimpse into one of the ship’s nice restaurants…

One final afternoon in a cozy nook to read a bit..

A final visit to the pub for a pint and trivia

We couldn’t resist this photo. This Thai waiter reminded us of Kim Jong-un – in both looks and personality….

A final show in the theatre….

These are the nice people, all Brits, who have been our dinner tablemates for the cruise. We had the 8:30 seating which we liked, although it made for late nights if we did a 10:30 show after dinner

This kind man, a Filipino, has been our waiter every night. He knows I like hot sauce and sets a bottle of Tabasco next to my place setting each evening….

George and I checked out the Churchill Cigar Room. He bought a Cuban cigar when we were in Tenerife, then enjoyed it under the guidance of Churchill…..

Boy – did it stink!

Saying a final goodbye to my good friend, the Queen, as we disembark, after 17 days together on the high seas.

Next stops – Capetown, the South African Wineland Area, Botswana, Victoria Falls, Johannesburg, then……???? No plans yet.

BOOKS: The Crowded Grave, another French mystery by Martin Walker. Again, I like his books as they remind me of the village where we housesat not far from Bordeaux. 5 stars out of 5

Namibia….What a Pleasant Surprise!

LOCATION: Docked at Walvis Bay on the SW coast of Africa. Sailing on the Queen Elizabeth from England to Capetown, South Africa

WEATHER: Nice. High 72. Mostly sunny

We docked in Walvis Bay, a port town of about 85,000 people in the country of Namibia. I have to admit I didn’t know much about this new country before. We were not expecting much, but were very pleasantly surprised. Here is its location.

We had splurged on one of the excursions offered by the ship. We had reservations on the Sandwich Harbor 4X4 trip at noon. So, with the morning free, we took a shuttle from the ship to a shopping mall. I was surprised to see a vibrant community with no obvious poverty. The mall had a few shops, but more importantly offered a coffee shop with wifi. (Hence, the last grouping of blog and Facebook posts.)

On our way back to the ship, we stopped at this little market where locals were selling some of their handiwork.There were 48 who had signed up for our trip. We were split into 8 groups of 6 each, in various 4×4 jeeps. It is customary to travel in convoys in case one of the jeeps gets into trouble.

Our first stop was a bay where there are thousands of pink and white flamingos. Just beautiful…Then, a few miles to Africa’s largest salt producers. There are hundreds of acres of flooded areas where salt is mined. This is our jeep driver showing us one of the salt the pink water…After about a mile, the hardened salt road ended and we started our off-road adventure. Away we go!!!

We followed the beach, driving just inches from the sea. We passed several seals sunbathing, and a jackal just waiting to grab one of the seal babiesThe entire area is a national park. We stopped at a pit stop where our driver cautioned us that this would be our only opportunity for a toilet.Then the fun really began. Our convoy turned inland toward the massive sand dunes. We went up and down – like a roller coaster.. Some of the angles were more than 45 degrees. A bit scary.One of the jeeps got stuck going up one of the steep dunes, and had to back up and start again. The trick is to zoom up fast.

We stopped at Sandwich Harbor. This entire coastline is called the Skeleton Coast, as so many ships in the past crashed along the seashore.Another stop was an unexpected lunch. The jeep drivers brought out tables, nibbles, beer, wine, pop, and water. Quite civilized in the middle of the desert!Our driver/guide was quite good. He spoke English to us, but Africaans to the other jeep drivers.

On our way back from the 4-hour trip, we passed some springbok and these ostriches….One of the other guests in our 6-person jeep was one of the lecturers from the ship. She is a well-known BBC reporter, and has presented lectures from her reporting in Afghanistan, Korea, and Russia. She seemed very nice, and politely reminded me to fasten my seat belt during the scariest parts of our dune excitement.

Back on board, we showered, and shook out about a cup of sand from our shoes. The cruise offers each of us comfy terrycloth bathrobes. We popped open the bottle of champagne that I had won dancing one night, and celebrated the end of a very nice afternoon.The captain makes general announcements every day. Today she spoke about the demographics of the ship’s population. Of the 1900 guests, about half are Brits. Next is Australians with about 25%, and the rest of us represent 25 countries. There are 30 Americans; we have met 4. About half of the 1000 crew are from the Phillipines. The others come from 47 different countries, with just one from the USA. Quite an international group!

DINNER: George had beef and I had a vegetarian Indian biryani. We chatted excitedly with our tablemates who had taken different excursions today and compared notes.We went to a comedy show, and then an early night.

Cruising the South Atlantic from Equator to Namibia

LOCATION: Slightly south of the Equator, along the coast of Africa – Libya, Cameroon
WEATHER: More sun, High 90

There are a lot of sun-burned Brits on board. One of our tablemates is brown as can be. She spends almost the entire day, each day, lying in the sun.

Today was a food festival. One of the chefs carved an ice sculpture on deck in about 15 minutes. Fascinating, and it must have been very challenging as the ice was quickly melting in the hot sun.

Then, there was an exhibition of other chefs’ handiworks in the ballroom. There were various stations – vegetable food carvings, pastry sculptures, bread artwork, and a sushi station.

I was invited to help make sushi rolls.

We could taste from each station. I passed on the patisserie and chocolate fondue stations, but made a bit of a pig of myself with the sushi.

There are beautiful live and fresh cut flowers all over the ship. The arrangements in the main lobby are especially impressive. They are changed every few days.

Each day we receive the “Daily Programme” with the following day’s offerings. It is always exciting to see what is up next.

In the last few days, we have enjoyed some excellent lectures on topics such as African Bushmen, Elephants, Moon Space Program, and Britain’s early ships.

We even had a lecture about Salvador Dali, and learned that he was a good friend of Walt Disney…..who knew? They even collaborated to produce a short (really weird) film.

There was a series of 3 lectures about Japan.

There are other things we don’t participate in, such as a darts tournament….

Nor gambling….

One afternoon, we watched a “Float Your Boat” contest to see which tiny ship, made by passenger teams, would float the best. Outstanding work!

And another day, we participated in a wine festival, tasting wines from around the world…

Meals continue to be great. Some of our recent entrees have been seared tuna, orange roughy, veal, and mahi mahi. One night, we skipped the sit-down dinner and ordered pizzas from the informal dining room.

The performances continue to be excellent. We attended the musical “Top Hat” performed by the ship’s actors and a vocalist who sang songs by Andrew Lloyd Weber. The ship has its own orchestra that accompanies each of the guest performers. They are superb, too.

Graduating from Pollywog to Shellback, then on to Namibia

LOCATION: Along the western coast of Africa sailing on the Queen Elizabeth.
WEATHER: Sunny. Hot. High 90

Today we crossed the Equator, around 2:00 PM, and the ship went all out for a big celebration. Years ago, the early sailors conducted an elaborate and somewhat dangerous ceremony for the crew who crossed the Equator for the first time. Now, the ship puts on a bit tamer, but similar, ceremony.

King Neptune ruled, and was elegant in his speech, with playacting pirates who had captured our ship. All a part of the “Crossing the Line” Ceremony.

We were 2 of the lucky 36 pollywogs (those who haven’t crossed the Equator before by ship) who volunteered to be in the show. We were warned to wear our swimsuits and to be prepared for a lot of goo. Almost everyone on board (2000 folks) gathered around the pool and upper deck to watch the ceremony.

We 36, in small groups, were seated around the pool while a “court” with a judge proclaimed we were guilty of a myriad of sins. After being judged guilty, we were doused, and I mean doused, with huge globs of food. The food, like bins of rice gruel, pudding, and noodles had been sitting in the hot sun for a few hours, so it was good and ripe. They dumped buckets of this warm, slimy food onto the 36 of us. It started smelling and feeling like vomit. Then, we were allowed to jump into the pool to wash off. (The pool soon turned into a gooey mess, too). At the end, we kissed a fish, which was also part tof the ceremony. All great fun as we evolved into Shellbacks – those who have crossed the line and survived.


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LUNA SEA The Anniversary 2017 at Nippon Budokan 29052017

Ever since the news about this anniversary live at Nippon Budokan was announced last year on the 23rd of December, I’m sure all SLAVES have been waiting for this day to come! We’ve definitely been missing them loads! Fans were already eagerly clapping along with the music that was playing before the concert started, and were waiting patiently although the concert started 20 minutes after stated time. Shinya’s neon green drum set, positioned at the center of the stage, quickly caught the attention of the attendees. He had posted a photo of it on his Twitter account earlier that day.

The classical piece, Moonlight Sonata, started playing as the arena darkened, and the members came out on stage one by one. Cheers from the fans were totally ground shaking at that moment. The first song, Metamorphosis, was a loud and powerful number, featuring SUGIZO’s out-of-this-world guitar riffs, and powerful drumming from Shinya. The audience was already all fired up and pumping their fists in the air. Others were head banging to the rhythm. Considering it was only early into the concert, how much more explosive can it get? The answer: A lot!

The next song, Precious, opened with a burst of fireworks on stage. As the fans were seated all around the stage, the band members would sometimes turn and face those sitting behind them as well. The head banging continued with the next few songs, Dejavu, JESUS, and Image. SUGIZO, guitarist INORAN, and bassist J gradually ventured onto the extended walkways to greet the fans seated on the first level. Some lucky fans even got to shake hands with SUGIZO! The band took a break, and vocalist Ryuichi addressed the crowd. He welcomed everyone and thanked them for coming. He also added that it was amazing that LUNA SEA had turned 28 this year, and promised that they would continue to do music even at 70 years old. No matter where they might be at that time, they would be rocking harder than ever! The End of the Dream and HURT were up next. The camera focused on SUGIZO’s guitar, which had the words, “Save Syria” in LED lights, a very important message to everyone in the world.

Then came a ballad number, NO PAIN. A curtain made up of LED lights, which was hovering above the stage before, now lowered onto the stage, enclosing the band in a “cage”. Images were then displayed on the LED light curtain. Next up was I’ll Stay With You, which continued the current laid back mood. SUGIZO opened the song on his violin, and INORAN and Ryuichi switched to acoustic guitars.

Then, it was time for some solos! Shinya was the first to present his solo, and drummed to an Arabic-sounding backing track, as the curtain of LED lights lifted slowly off the stage. As the fans shouted, “Shinya!” He played along, gesturing to them that they were not loud enough, and led them to shout his name in between the drumbeats.  “Give me more!  More!  Can you guys do it?! Can you?!” shouted Shinya, before assuring the audience that they were the coolest. At the last beat, three puffs of smoke erupted from the sides of the stage! Next up was J with his solo. He whipped out his bass, which was bright red, with the face of what looked like Mother Mary, on it. The arena sort of turned into a club, with lasers everywhere, and the strong beats from the back track that J was playing to. Shinya meanwhile started tossing his drumsticks to the crowd behind. J got the audience to shout, “Hey! Hey!” with him, as Shinya came in on the drums. J gave a shout out to the audience in the front, as well as right at the back, not forgetting those who were watching the show at the live viewing. “Budokan is the best!” he shouted. The rest of the band returned to the stage to play BLUE TRANSPARENCY, before leading into the next MC.

Ryuichi mentioned that LUNA SEA had met with many rainy days whenever they held their concerts, but the weather that day was perfect! He also said that although LUNA SEA had performed there six times, it still felt good to be back. He expressed his heartfelt thanks to all the fans who have supported LUNA SEA, and enabled them to continue doing music for 28 years, and would like to dedicate the next song, I for you, to all their fans. The atmosphere changed as mirror ball lights were projected all around the Budokan. That would not be complete with a soulful guitar solo by SUGIZO.

Another series of upbeat numbers began with the song, STORM. “Budokan! Can you guys give us some more! Please do whatever you want as long as you don’t hurt yourselves!” shouted Ryuichi. Emotions were running high as fans pumped their hands in the air to the beat. It was my personal favourite of the night as well, with SUGIZO’s awesome guitar solo. With no break in between, next up was TIME IS DEAD. The audience chanted, “Time is dead! Time is dead!” INORAN and SUGIZO came together and made a heart-shaped sign towards the audience at the back of the stage. Four of the members gathered to the center of the stage, and Ryuichi shouted, “Let’s go for more! Are you guys ready?” The audience was even more fired up with the next song, ROSIER. The main set list ended with Metamorphosis, and the members left the stage one by one. During the short break before the encore, the fans whipped out the fan-made blue pom-poms which were distributed earlier on, and also turned on their phone torches, making the Budokan look like it was filled with stars. They waved their phones while singing a birthday song to LUNA SEA. It was definitely an amazing sight.

The band came back on stage, wearing the concert tees, and thanked everyone for singing the birthday song. SUGIZO even threw his scarf into the crowd! The audience continued waving the blue pom-poms in the air during the next songs, Anthem of light and TONIGHT. It was now time for an introduction of the members, with Shinya going first! Ryuichi went, “let me introduce the best drummer in the universe!” and the audience shouted Shinya’s name loudly. The audience went on to shout the members’ names when they were introduced. When INORAN was introduced, he gave a slight bow, and said a few words. “I remember the time when we were doing a gig at a livehouse, when Ryu was not with us yet. He would come to see our gigs, and bring us food! Once, he brought us donuts, but when I opened the box, there was only one left!” he remarked. “Do you really need to say this here? I was sure that there were five in there though. Shinya, you ate them all, did you?” said Ryuichi. SUGIZO continued the donut story, saying that he remembered seeing two donuts in there. Ryuichi insisted that the “boss” should say a few words, and directed everyone to Shinya. “Hi! I’m the boss!” said Shinya.  “I remember that during those times, Ryuichi had green hair, and no eyebrows! To commemorate the green hair, we made the drum set green today!”

Laughs aside, Ryuichi announced to the audience that LUNA SEA would be releasing a new album by the end of this year, and teat the theme would be “love”. They chose this theme to remind everyone how important “love” is, amidst the horrible things happening around the world today. He also announced, on behalf of the band, that they would be having two days of concerts at Saitama Super Arena, this Christmas, on the 23rd and 24th of December. Streamers shot out from the stage at the beginning of the next song, Wish. The band paused after this song, and the members walked around the extended walkways to greet the fans. The fans started shouting for an encore again as the members huddled together at the centre of the stage, as though they were discussing something. Ryuichi finally announced, “we don’t want to leave just yet! Thank you all again for supporting us!”

The guitarists switched to acoustic guitars and sat down on stools to play the final song, MOTHER. SUGIZO then switched to his violin, halfway through the song, to perform his violin solo. After the final song, LUNA SEA gathered at the center of the stage and linked arms. All the members of the audience linked arms as well, and did a small jump together with LUNA SEA. It was certainly a night to remember, for all the fans present.

We wish LUNA SEA a very happy 28th anniversary and definitely hope that they’ll continue to make and perform music as long as possible!

LUNA SEA The Anniversary 2017 at Nippon Budokan 29052017 setlist

  1. Metamorphosis
  3. Dejavu
  4. JESUS
  5. Image
  6. The End of the Dream
  7. HURT
  8. NO PAIN
  9. I’ll Stay With You
  10. Shinya’s drum solo
  11. J’s bass solo
  13. I for You
  14. STORM
  16. ROSIER
  17. Metamorphosis

  1. Anthem of Light
  3. WISH

As reported by Elenaril

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What is Rendon City Business Directory About?

Rendon City Business DirectoryLocal Patriotism is what Rendon City Business Directory is about!

Thanks for visiting our Rendon City Business Directory. Our directory is mainly about connecting the local citizens to the local businesses. We also designed the directory to give you more than just a local business search. We want to help you find local news and events, to keep you informed of what’s going on locally. We want to help you support your community finding places to get involved in local events.

Since we are all about connecting you with your neighbor’s businesses, we also want to ask you to help us to do that. Please tell local businesses in your community about the Rendon City Business Directory and send us information about local news and events.

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We have many categories in our Rendon City Business Directory but we made a special Rendon Texas Events page to help connect the people of Rendon Texas with their neighbors. If you have a Rendon event you would like for us to list please contact us with the details. We want to post these events and help everyone in Rendon find out what’s happening locally. We strive to maintain quality listings and we want to hear feedback from our visitors. Let us know how we can help.

We appreciate you visiting our web site. We hope you find the articles we wrote informative and that you enjoy the local news, weather and events pages. It is most likely that you are a resident within our region, or found us on a Google search. If you are looking for information in another city besides Rendon, we have the Tarrant County City Directory and Johnson County City Directory links in the left column of most pages. These directories will give you additional city searches. Please feel free to ask us any questions on our contact page. We will be glad to answer your questions about our city business directory services we offer.

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3000 m
Jacuzzi and paddling pool
Directly on the Adriatic Coast
Swimming pool with sun loungers
Beautiful beaches nearby
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    Campsite Paradiso (Marche), Marche

    The family-friendly Paradiso Campsite is situated in the middle of Monte San Bartolo Nature Park in Casteldimezzo, an idyllic little village in the Marche region of Italy. Approximately five kilometres from the campsite lies the town of Gradara where you can find a supermarket that sells food and drinks. Paradiso Campsite stretches out over terraced grounds and offers spacious plots with plenty of shade and guarantee a relaxing family holiday in a beautiful woodland setting.

    The small pool offers refreshment on hot days with a Jacuzzi and a special area for kids. A path runs right through the nature park, offering a stunning panorama view of the coastal region, and takes you directly to the beach on the Adriatic Sea in roughly fifteen minutes. The beach can also be reached by car.

    Paradiso Campsite offers great leisure facilities for its guests. From the terrace of your accommodation you can enjoy a beautiful view of the surrounding hills of the Marche region which is characterised by hilltop castles, vineyards and forests. You might even catch a glimpse of some deer or stags straight out of the forest next to your accommodation ─ your children will love it! The campsite, which is surrounded by lush Mediterranean vegetation, has its own pool and surrounding sun terrace. For the kids there is a small playground. You can reach various parts of the beach with a short walk. If you need to grab some every day essentials then head to the campsite’s own minimarket where there is a small selection of food and drinks including fresh bread and rolls. If you don’t fancy cooking then treat yourself to a freshly baked pizza in the pizzeria or visit the restaurant.

    The landscape of the Marche region is characterised by green hills and beautiful medieval towns and villages. Near Gabicca Mare you can find numerous beaches including Vallugola beach with its pretty harbour, Baia Flaminia’s softly sloping beach and Fiorenzuola’s natural beach. Visit the university town of Urbino and have a look at the Palazzo Ducale. The centre of San Marino is also historically very impressive. It is worth taking a trip to the aquarium in Cattolica which also offers lively boulevards and plenty of shops. A particular highlight is Gradara Castle that dates back to the twelfth century.
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Dermal exposure assessment to benzene and toluene using charcoal cloth pads

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Author: Wendel de Joode, B. van · Tielemans, E. · Vermeulen, R. · Wegh, H. · Kromhout, H.
Institution: TNO Kwaliteit van Leven
Source:Journal of Exposure Analysis and Environmental Epidemiology, 1, 15, 47-50
Identifier: 238301
doi: doi:10.1038/sj.jea.7500349
Keywords: Health · Food and Chemical Risk Analysis · Benzene · Charcoal cloth pads · Dermal exposure · Toluene · acetylcysteine derivative · benzene · charcoal · organic solvent · toluene · airborne particle · ambient air · article · clothing · concentration (parameters) · drug blood level · human · industrial worker · inhalation · job analysis · occupational exposure · occupational hazard · occupational toxicology · personal monitoring · petrochemical industry · skin absorption · Administration, Cutaneous · Benzene · Charcoal · Chemical Industry · Environmental Exposure · Environmental Monitoring · Humans · Job Description · Occupational Exposure · Permeability · Petroleum · Toluene · Volatilization

Charcoal cloth pads have been used to assess volatile chemicals on the skin in a laboratory setting; however, they have not yet been applied to measure dermal exposure in occupational settings. This study aimed at evaluating whether charcoal pads can be used to assess dermal exposure to benzene and toluene in workers of a petrochemical plant. Inhalation and dermal exposure levels to benzene and toluene were assessed for workers of a petrochemical plant performing different jobs. Benzene uptake was assessed by determining S-phenylmercapturic acid in workers' urine samples. Dermal exposure levels on the charcoal pads were adjusted for ambient air levels of benzene and toluene by subtracting the amount of benzene or toluene measured in personal air from the amount of benzene or toluene measured on the charcoal pad. In general, measured external and internal exposure levels were low. The estimated contribution of the dermal route to internal benzene exposure levels was less than 0.06% for all jobs. Toluene personal air concentrations and benzene and toluene dermal exposure levels differed statistically significantly between job titles. For benzene, differences between jobs were larger for adjusted dermal exposures (maximum 17-fold, P = 0.02) than for inhalation exposures (maximum two-fold, P = 0.08). Also for toluene, although less clear, differences between jobs were larger for adjusted dermal exposures (maximum 23-fold, P = 0.01) as compared to inhalation exposures (maximum 10-fold, P = 0.01). Charcoal pads appeared to measure dermal exposures to benzene and toluene in addition to ambient air levels. Future studies applying charcoal cloth pads for the dermal exposure assessment at workplaces with higher dermal exposure to organic solvents may provide more insight into the biological relevance of dermal exposure levels measured by charcoal cloth pads. In addition, the design of the dermal sampler might be improved by configuring a dermal sampler, where part of the sampler is protected against direct contact and splashes, but still permeable for the gas phase. This design would most likely result in a better ability to correct for airborne concentrations at a given body location.


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Oh Sarah McLachlan!

The Visit Review

The Visit | Repulsive Reviews | Horror Movies

Although I haven’t seen some of his most recent work, I have always been a fan M. Night Shyamalan’s older films like The Sixth Sense, Signs, and Unbreakable. Even with those great films under his belt, it seems that over the past few years, the writer and director has been getting quite a bit of negative reviews. I don’t know firsthand how his last couple of projects were, but I was certainly excited for his latest, after seeing a myriad of commercials and teasers all over the internet. I am elated to say that The Visit certainly met my expectations, effectively living up to the hype it created months prior.

Becca (Olivia DeJonge), 15 years old, and Tyler (Ed Oxenbould, Alexander and the Terrible, Horrible, No Good, Very Bad Day), 13, are going to visit their grandparents for the very first time. After a long train ride, they are greeted with open arms by Nana and Pop Pop. It doesn’t take long, however, for the children to notice that their grandparents are exhibiting some extremely strange behavior, causing some alarm and the children to want to end their visit a little early…

While found footage films seem to be everywhere these days, it is a first for prolific writer, director, and producer, M. Night Shyamalan. More of a mockumentary than a found footage film per say, The Visit is technically being shot by aspiring filmmaker, Becca, who happens to be our 15-year-old protagonist. This style of filming happens to be quite fitting for the story-line actually, producing a more personal touch for a film that is essentially about family and the mending of close relationships. It is shot extremely well for a found footage type of movie and doesn’t come off as low-budget or trying to cut any corners just for the sake of ‘authenticity.’

Within the first 15 minutes or so of pressing play, I was already convinced that The Visit featured a talented cast. The two young stars, Olivia DeJonge and Ed Oxenbould, playing Becca and Tyler respectively, were outstanding from start to finish. I loved them together on screen, as they managed to create a very believable and natural brother/sister dynamic, and the character development created by Shyamalan, coupled with the duo’s acting chops made for a really great experience. I actually became more invested in the characters with each progressing scene, which doesn’t happen very often in the horror genre these days, sadly.

The Australian born youngsters weren’t the only impressive performers that The Visit had to offer, however. Our sweet old Nana and Pop Pop were played by Deanna Dunagan and Peter McRobbie, who both did a wonderful job with their respective roles. They were both extremely creepy, for lack of a better term, in their own distinctive ways — McRobbie with a subtle, silent approach and Dunagan with a more in-your-face, screaming, scratching at the walls type of hair-raising. The Visit got extremely eerie a lot sooner than I had anticipated, thanks to the very physical performance by Dunagan, or presumably her stunt double, crawling under the house during an impromptu hide-and-seek game, or her naked paint-scratching sessions, during one of her ‘sundowning’ episodes. Kathryn Hahn was also impressive as the children’s mother. I am used to seeing her in more comedic roles similar to her role as Alice in the hilarious Step Brothers, so it was a nice surprise to see her in a more serious fashion.

Perhaps one of the things that Shyamalan is best known for is his twist endings. While I was trying to figure out all sorts of convoluted possibilities for the climax of The Visit the entire time, I kind of missed the most obvious one, which happened to be what actually is presented to us. While saying that it is ‘obvious’ may sound like a bad thing, I can assure that it is not. The ending is actual deeply rooted in a very real realm of possibility, which further cements the effectiveness of this film. I thought it was a fitting end to a great film and I am happy with the entire production, overall.

I am a fan of M. Night Shyamalan and stand firm in my opinion that he is a great filmmaker. No writer or director is going to be able to make films that please everybody 100% of the time, but I appreciate his diversity and his persistence. The Visit proved to be a great film and I am extremely happy to have it in my ever-growing film collection. Included in the Blu-ray home release of the film is a 10 minute behind-the-scenes featurette on the making of the film. It does a fantastic job of purveying Shyamalan’s passion for filmmaking and gives a very small glimpse into his style of creating, which I found very fascinating.

The Blu-ray also offers an alternate ending, deleted scenes, and a collection of Becca’s photographs from her stay with her grandparents. Be sure to purchase a copy of The Visit on Blu-ray combo pack and DVD on Tuesday, January 5th from Universal Pictures Home Entertainment.

I give this film a Repulsive Rating of 4.5 white rapper freestyles out of 5.

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Increased risk of non-alcoholic fatty liver disease in women with gestational diabetes mellitus: A population-based cohort study, systematic review and meta-analysis.

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America’s Gulf Crisis: A Long-Term Recovery Plan after the Deepwater Horizon Oil Spill

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The Obama Administration in the fall of 2010 put forward an aggressive long-term recovery plan, including a call for dedicated funds, to help strengthen the Gulf region’s environment, economy, and health following the Deepwater Horizon oil spill. This report provides recommendations on five topic areas to ensure a seamless recovery and restoration effort in Gulf Coast. In summary, this plan encompasses five topic areas critical to the longâ€term recovery of the Gulf region:
  • Proposal to Congress to Dedicate Clean Water Act Civil Penalties to the Gulf Coast
  • Longâ€Term Ecosystem Restoration
  • Health and Human Services Recovery
  • Economic Recovery
  • Nonprofit Sector Recovery
Additional recommendations outlined in the report include that the Departments of Health and Human Services, Commerce, Agriculture, and Labor, in conjunction with the Small Business Administration (SBA), the Internal Revenue Service (IRS), the Corporation for National Community Service (CNCS), and other agencies, continue their important recovery work in close coordination with state and local governments and organizations.

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Get e-book Kaufmans atlas of mouse development supplement : with coronal sections

Free download. Book file PDF easily for everyone and every device. You can download and read online Kaufmans atlas of mouse development supplement : with coronal sections file PDF Book only if you are registered here. And also you can download or read online all Book PDF file that related with Kaufmans atlas of mouse development supplement : with coronal sections book. Happy reading Kaufmans atlas of mouse development supplement : with coronal sections Bookeveryone. Download file Free Book PDF Kaufmans atlas of mouse development supplement : with coronal sections at Complete PDF Library. This Book have some digital formats such us :paperbook, ebook, kindle, epub, fb2 and another formats. Here is The CompletePDF Book Library. It's free to register here to get Book file PDF Kaufmans atlas of mouse development supplement : with coronal sections Pocket Guide.
  1. Associated Data
  2. What is eHistology
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In Section 4 we describe new data-types now available from EMAGE including gene and regulatory expression patterns and the results of clonal analysis encoding fate maps and lineage and in section 5 the recent developments linking the eHistology resource to the high-resolution phenotype data now analysed and published by the Deciphering Mechanisms of Developmental Disorders DMDD on-line resource.

We have utilised this capability to provide an interactive 3D viewer showing a surface rendering of the defined anatomic components Fig. This supercedes the Java-based viewer we had implemented previously Feng et al. The new visualisation is controlled by the anatomy tree provided in the section browser Fig. There is the additional option to view in wireframe mode for the larger models, which may display slowly. We have enabled this functionality in all our embryo models and so provide 3D anatomy of the developing mouse from implantation, through gastrulation and neurulation, and into mid- and late-stage embryogenesis.

A Surface-rendered views of Theiler stage 21 top left , Theiler stage 24 top right , and Theiler stage 25 lower left and right mouse embryo models with delineated anatomy can be interactively explored using a web browser. Navigation controls are provided in the left panel and include: pan-and-zoom; translating the viewing plane distance ; and rotating the viewing plane in 3 dimensions pitch, yaw. The central panel shows a section through a 3D model with delineated anatomy shown in various colours.

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An anatomy tree in the right panel is used to visualise delineated anatomical domains. Clicking on 3D view top right opens up the selected anatomical domains as a surface rendered object in a separate window.

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Uniquely, the section viewer allows visualisation of anatomy on a section of arbitrary orientation through mouse embryos. Specific anatomical components can be toggled on or off through their selection in the anatomy tree or by clicking directly on a component displayed in the section of interest. Anatomy components selected in this way are automatically displayed in the 3D anatomy viewer including any colour selections.

An important feature of the section viewer is its ability to deliver sections through very large 3D volumes without the need for data download. This circumvents a common issue with many 3D viewer applications which require download of very large 3D volumes. IIP3D technology allows a single section through a 3D volume to be delivered and displayed, and consequently retrieving a section image is fast and can be accomplished on large volume 3D images Husz et al. The anatomy delineation process was undertaken by developmental biologists and anatomists and has involved delineation of visible anatomical components on a section-by-section basis through the 3D reconstruction of Theiler-staged mouse embryos.

To support the delineated anatomy, a mouse anatomy ontology was created that enabled the partonomic part-of relationships of mouse developmental anatomy to be rationalized and to be queried through computational means. To annotate the anatomy in the 3D reconstruction, each delineated anatomical component was assigned to a specific component in the anatomy ontology, and this enables the tree-view display that can be seen in the section viewer in the context of an interactive anatomy tree that displays the part-of relationships as sub-branches of the various anatomical components.

This process of delineation allows the 3D anatomy viewer to provide precise context for understanding mouse embryo development, and enables interoperability between the 3D atlas and the eHistology and EMAGE database resources such that an annotated component can be visualised in 3D alongside whole-mount and section data.

This interoperability allows for visualisation and communication of the relationship between gene expression and anatomy. A primary objective of the eMouseAtlas Project was to enable spatial mapping of whole embryo gene expression patterns to allow complex 3D gene expression patterns to be visualised, indexed, cross-compared and to deliver objective analysis using spatial analysis tools. The tools developed for internal use WoolzWarp use a novel 3D warping technique based on the constrained distance transform Hill and Baldock, , which allows interactive 3D mapping of the full image volume.

The mapping process utilises points of morphological equivalence that are defined on the source gene-expression data image and the stage-matched embryo model. These points define the spatial warp that maps the original data image into the space of the reference model. Having defined the transform, the signal in the original image is extracted and a representation of the original pattern is defined within the space of a 3D atlas model, without the constraint of anatomical boundaries.

Mapping gene expression patterns in this way provides an objective and accurate representation of the whole embryo expression patterns and additionally captures information on expression gradients.

Multiple mapped expression patterns can then be visualised and cross-compared in a common spatial framework Fig. A Volume rendered views of 19 E These visualisations can be used to cross-compare gene expression patterns in a spatial framework. B Point-cloud rendered views of spatially mapped E An advantage of the point cloud visualisation is that a user can see through the entire 3D volume, and can more accurately identify regions of expression. In Fig.

What is eHistology

Direct 3D visualisation of the expression profiles of all 19 Wnt family genes highlights the complexity of specific compartments of the embryo in terms of Wnt coexpression. Tools are needed to isolate coexpression domains in these complex 3D models, and these represent an important future development for this aspect of the project. In addition, there are key advantages in being able to sequentially order gene expression in compartments of the developing mouse embryo in these rich spatial datasets. For example, tools that would enable nested sets of gene expression and other hitherto poorly understood spatial relationships to be identified in these 3D models of gene expression may help us understand the regulation of Wnt gene expression.

From a visualisation perspective, mapped gene expression has additional complexities that we do not encounter with anatomical domains. In contrast to the 3D anatomy, where computational measures were used to ensure that overlaps did not occur, the molecular anatomical gene expression profiles in general overlap in 3D voxel-space and our core measure of putative coexpression can be calculated using the Jaccard index Armit et al.

To be able to identify whether genes are coexpressed overlap or show adjacent expression domains non-overlap we have developed a viewer that enables point cloud visualisation of the 3D molecular anatomy as this enables both overlapping and non-overlapping gene expression domains to be explored, and overcomes unwanted colour-mixing effects that are a feature of surface-rendered overlapping domains.

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In this example, it can be seen that a major advantage of using the point cloud visualisation is the ability to see through the entire mapped 3D volume. From a data mining perspective, we are additionally exploring computational measures that can be used to define adjacency, and to determine whether non-overlapping domains are coupled in other ways, for example whether they track one another longitudinally along the alar and basal plates of the developing CNS.

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It is anticipated that the 3D modelling and 3D spatial analysis approach outlined here will enable a deeper understanding of the role of genes in development, and may deliver powerful new tools that will allow researchers to explore the cross-regulation of key signal transduction pathways such as Wnt , Shh, Notch, and Fgf signaling pathways in the developing mouse embryo. The 3D atlas framework is a resource describing and defining the developmental anatomy of the mouse and was originally developed as a spatio-temporal framework for capturing spatially organised image data, specifically in situ gene-expression.

This is the basis of the Edinburgh Mouse Atlas Gene Expression EMAGE Database and provided a mechanism to index and collate spatial in situ patterns in an unbiased form and independent of the constraints of the underlying anatomical structures.

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All of these data are directly mapped to the 2D and 3D embryo models to enable spatial indexing, query, cross comparison and analysis. The mapping process involves accurate stage selection of mouse embryo models and spatial warping of raw image data onto a stage-matched model described in Section 3 and reviewed in Armit et al. This mapping process generates standardised representations of gene expression patterns that can be archived in the EMAGE database, and queried through a web interface.

New discoveries can be extracted using this web interface, and in Fig. This example query identified Foxa1 , Serpin6b , Slc35b4 , Nkx , and Tbx4 as the top 5 genes that show spatially mapped expression in the lung. Importantly, the first gene in this list — Foxa1 — was not text-annotated by the authors and so it would be impossible to find this gene through a text-based query for genes expressed in the lung. An additional advantage of this system is that expression patterns can be analysed spatially in relation to each other, allowing gene expression patterns to be ranked and clustered through computational measures of spatial similarity.

Each EMAGE entry details the expression pattern of a single gene at a single stage of development, and may include multiple images of an embryo specimen. A use case scenario in which an EMAGE spatial query is used to identify gene expression patterns in the developing lung. A A user-defined region pink on an embryo model is delineated using the Embryo Space paint query tool. The gene symbol entity detected , spatial annotation expression region , text annotation structures , and similarity score similarity to query region are all shown in the results table.

This example query identified Foxa1 , Serpin6b , Slc35b4 , Nkx , and Tbx4 as the top 5 genes that show spatially mapped expression in the E The first gene in this list, Foxa1 , was not text-annotated by the authors but was spatially mapped by the EMAGE Editorial Office and so could be retrieved by spatial query.

VISTA is a resource of experimentally validated human and mouse non-coding genomic DNA fragments with gene enhancer activity as assessed in transgenic mice Visel et al. This resource utilises Sleeping Beauty lacZ transposons that have been randomly integrated into the mouse genome. Hundreds of insertions have been mapped to specific genomic positions, and the corresponding regulatory potential is documented through lacZ imaging of E Through spatial mapping of the lacZ expression patterns, the EMAGE gene expression database enables rapid identification of cis -regulatory elements that are expressed in a region of interest in the mouse embryo.

Additional query capabilities - such as the find similar query - enable co-localisation and co-expression of regulatory elements to be explored computationally and allow the VISTA and TRACER datasets to be spatially compared with ISH gene expression profiles. Lineage tracing is a powerful means of describing recruitment of cells to various tissue compartments reviewed in Wilson and Lawson Importantly, studies of clonal analysis that utilise labelling of individual cells enrich our understanding of developmental processes and can reveal cryptic boundaries that may exist within the developing embryo.

We have collaborated with Drs Val Wilson and Kirstie Lawson of the University of Edinburgh to develop a clonal analysis database that allows researchers to explore patterns of genetic mosaicism that have been uncovered in the mid-gestation mouse embryo. Dr Val Wilson's group have utilised a single-cell labelling method that relies on the spontaneous reversion of an inactive lacZ gene laacZ carrying a sequence duplication to an active lacZ reporter Tzouanacou et al. In addition, the size of the clones allow for estimation of the time at which the progenitor cells were labelled.

In addition, a mapping between the annotator's in-house scoring criteria and the EMAGE nomenclature was used to describe whether clones are present or not detected in a specific anatomical component. In future developments we wish to develop clonal maps with the aim of capturing clone distribution in a spatial model. Dr Val Wilson's group have captured this spatial information as part of their annotation process Fig. A spatial model for capturing clonal analysis data. These entries include text-annotation provided by the original authors.

B Clonal analysis maps used by the authors as part of their annotation process can additionally be incorporated into EMAGE entries and used to capture clone distribution.

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Reprinted from Fig. S4 in Developmental Cell 17, Tzouanacou et al. The eHistology resource provides online access to cellular-resolution images of the histology sections used in Kaufman's The Atlas of Mouse Development Graham et al. The original publication of this book by Kaufman is the definitive work for mouse developmental anatomy. The eHistology resource has now been extended to include the annotated coronal sections published in Kaufman's Atlas of Mouse Development Supplement Price et al.

This dataset catered for a specific demand from the neuroscience community for annotated coronal sections that could be used as a reference atlas, and includes detailed annotation of the brain at E11, E These sections include some original annotations from M. Kaufman supplemented by more detailed brain annotations. The DMDD interface provides orthogonal views through the embryo data and the eHistology web-service API can be used to discover a closely matching annotated view of the high-resolution histology Fig. We anticipate that this interface will provide a key service for the similar International Mouse Phenotyping Consortium IMPC resource and expression atlases.

B The supporting eHistology image for the section plane shown in A highlights multiple anatomical components that researchers should additionally consider when evaluating phenotype image data. The web tool we have delivered enables image matching between DMDD and eHistology resources, such that for any given section through a DMDD image volume the closest match from the eHistology Kaufman atlas can be retrieved.

We have recently developed a new eLearning resource that provides short and interactive vignettes in embryo primarily vertebrate development, from gametogenesis through to organogenesis Fig.

VIAF ID: 14251905 (Personal)

The resource describes the development of various anatomical systems including the cardiovascular system, nervous system, and musculo-skeletal system, and additionally introduces core developmental biology concepts such as gastrulation, placentation, and the formation of the germ layers. A An animated tutorial is presented in the central panel. The accordion selection tool to the right of the page links to accompanying 3D visualisations. B The eLearning 3D viewer shows a 3D surface reconstruction of an embryo model, combined with a section through the 3D volume.

In this example, the developing nervous system is delineated. By doing so, this viewer enables the detail provided on section to be shown in the context of the 3D anatomy. The navigation tools allow a user to change the section plane. The resource combines illustrative animations of embryonic development with interactive 3D visualisations of mouse developmental anatomy.


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The Wizard (1989)

In this episode, Peter and Ray revisit the 1989 classic, The Wizard. Does this movie about promoting the NES and Super Mario Bros. 3 still hold-up or does it need to stay in the 1989? Listen to find out!

Listen to next week's podcast when Peter and Ray jump back a few years to revisit, Pee-wee's Big Adventure.

Links: Fred Savage's style

Contact Us: Twitter | Facebook | Email- RetroReviewsCast[AT]gmail[DOT]com |  Donate

Credits: Album art created by friend of the pod Lis. If you are interested in seeing more of her artwork, you can visit her Etsy store and check out her Insta.

Music for this episode is provided by FMA and created by Audiobinger- "Pre-Game Warm-Up".

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Figure 5 | Retrovirology

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From: Anti-adult T-cell leukemia/lymphoma effects of indole-3-carbinol

Figure 5

Effects of I3C on the expression of cell-cycle and apoptosis regulatory proteins. Western blot analysis of HUT-102 and TL-OmI cells treated with I3C. (A) Cells were treated with I3C (100 μM) for the indicated periods. (B) Cells were treated with I3C at the indicated concentrations for 48 h. Total cellular proteins (20 μg per lane) were separated on SDS-polyacrylamide gels and transferred to the membrane. Protein levels were detected by Western blotting with antibodies directed against each protein. (C) Total RNA was extracted from HUT-102 and TL-OmI cells following treatment with I3C (100 μM) for 12 or 24 h. The mRNA expression of Tax and HBZ was analyzed by RT-PCR analysis. β-actin served as an internal control in the RT-PCR procedure. Representative data of three experiments with similar results.

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Tag Archives: Transfigutation

Sermon: Sojourning in the Valley

But I’ve preached on Transfiguration’s amazing theophany for the past two years, and so today I want to focus instead on the valleys. Because there are no mountains without valleys; there are no mountain-top experiences without hard times. Continue reading

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Rhyming Picture Book Cake for Everyone! Tuesday

Rhyming Picture Book Cake for Everyone! Tuesday         Day 31

RhyPiBoMo Souvenirs…so you don’t forget me! LOL

I have had quite a few people ask if I will be selling any RhyPiBoMo items. It didn’t occur to me in the beginning and then I didn’t have the time to set it all up during the event, but I’m thinking that I will look into it more next week.

Please comment if you would be interested in purchasing a coffee mug or a notebook with RhyPiBoMo on it. Or, suggest anything else you might be interested in. I did look into CafePress as an option.

I’m also going to offer some of the graphics that I created here this month for sale. I just ordered a few of them in 8×10 poster size that would be a nice visual to refer to when writing. I am doing this to offset the cost of the prizes and shipping involved for the Rhyming Parties.  I would like to continue these parties once a month but need to generate a little money to keep offering prizes…it would also make Mr. Karcher happy if I at least break even! LOL

These are the objects I’m referring to…

RhyPiBoMo Notebook      RhyPiBoMo Mug

Let me know if you are interested in purchasing

a notebook or coffee mug?

Today’s guest blogger is someone I added to my list of guest bloggers right from the beginning.  She is a wonderful writer, I’ve heard, an amazing teacher and an awesome blogger. When I asked, she mentioned that she doesn’t write everything in rhyme and wasn’t sure if this was the place for her…If you read her rhyme, you will see how modest she is…and what a great rhymer she is too! She will tell you that she likes to hang out at dessert tables so maybe she will taste a bit of our rhyming picture book cake! LOL I first found her when she was hosting a writing contest on her blog  http://susannahill.blogspot.com/

You must check it out! I am hoping to take her Making Picture Book Magic class in the fall, when life slows down a bit. Here is the link: http://www.susannahill.com/MAKING_PICTURE_BOOK_MAGIC.html   I have heard such great things about her class! You should check it out!

So, without further ado, I’m honored to present today’s

Golden Quill Guest Blogger

Susanna Leonard Hill!

   Rhypibomo Guest Blogger Badge   Susanna Hill 1

Accidentally In Rhyme

Hey there!
Hill’s the name, and rhyming’s my game!
Except… uh… it’s not actually.

(No one was checking ID so I just sauntered past Angie while she was chatting with the RyPiBoMo guests who actually know what they’re talking about. I hung out by the dessert table and tried to look like I belonged. It was surprisingly easy for someone who is not normally good at subterfuge.)

dessert Table
So how am I doing? Do I blend?

Because here’s the thing: I write stories in rhyme. Some of them have won prizes. Some of them have been published! But all the while I’m carrying a guilty secret, just waiting for the moment when someone cottons on, because… *draws shaky breath in readiness for confession*… I have no idea how I do it.

I said it.
I’m a rhyming accident.
I don’t know any of the rules.
I don’t know an anapest from a dactyl from an iamb – they’re all Greek to me.
Caesura? I’m pretty sure that’s a hairstyle popularized by Julius and Augustus.
Enjambment? I think that might be a kind of raspberry sauce.
So what am I doing here? you ask.
Well, I’ll tell you.

I’m here to let you know that you don’t have to know all those poetic terms to write rhyming picture books. (Don’t tell my high school English teacher I said that.) You just have to be able to feel.
Rhyming poetry is like music. It has a rhythm – a rhythm you can feel.

Have you ever seen Footloose (the original fantastic one with Kevin Bacon, not the dreadful remake =)?

Do you remember the scene where Renn is trying to teach Willard to dance? They clap hands to the beat of the music, and bang on the dashboard, trying to get Willard to feel the rhythm.

You can do that with poetry.
Let’s try it first with something easy.
Think of childhood songs like Itsy Bitsy Spider, London Bridge, The Farmer In The Dell, BINGO, Twinkle Twinkle Little Star, and Yankee Doodle. You can learn from them.

Sing one of them. Right now. Don’t worry, you’re in a judgment-free zone. Let’s try a rousing chorus of Twinkle Twinkle. Are you singing? Feel how you naturally put more stress on some syllables than on others…

HOW i WON-der WHAT you ARE
LIKE a DIA-mond IN the SKY
HOW i WON-der WHAT you ARE

Tap it out on the table while you sing – a strong tap for the word or syllable that the song makes you want to accent (i.e. put more stress on) and a lighter tap for the softer, less-stressed syllable. Or, if you’re a get-up-and-go type, walk around the room. Take a heavy step for the accented words/syllables and a tiptoe step for the softer/unaccented ones.

Are you feeling it?

You can use songs like this, or well-known nursery rhymes, or even the rhyme structures used in the picture books of all the fabulous writers who have posted this month as models for your own rhymes. Read the song, nursery rhyme, or picture book rhyme aloud. Find the pattern of accented/unaccented. Tap it on the table or walk around the room. Feel the rhythm. Then copy the pattern with your own words.

Now let’s try it with a plain rhyme (no music). Don’t be scared. You can do it!

Susanna Hill 5

FREIGHT train’s PULL-ing FROM the YARD.
LOC-o-MOT-ive’s WORK-ing HARD.
“SAFE trip!” CALLS the STAT-ion-MAS-ter.
CHUG-ga, CHUG-ga, TRAIN rolls FAS-ter.

See? It’s not that hard.
All you have to do is pick a rhythm and stick to it!

Now, if you’ll excuse me, I’m going back to hide behind the dessert

Susanna Leonard Hill is the award winning author of nearly a dozen books for children, some of which accidentally rhyme. Her titles include Punxsutawney Phyllis (A Book List Children’s Pick and Amelia Bloomer Project choice),No Sword Fighting In The House (a Junior Library Guild selection), Can’t Sleep Without Sheep (a Children’s Book of The Month), and Not Yet, Rose (a Gold Mom’s Choice Award Winner.) Her books have been translated into French, Dutch, German, and Japanese, with one hopefully forthcoming in Korean. Her newest book, Alphabedtime!, (one of the accidental rhymers) is forthcoming from Nancy Paulsen Books, an imprint of Penguin Books, in Fall 2015. She lives in New York’s Mid-Hudson Valley with her husband, children, and two rescue dogs.

Website: http://susannahill.com/home.html

Here are a few of Susanna’s wonderful books:

Susanna Hill 3 (2)

Susanna Hill 2

Susanna Hill 4 (2)

Thank you Susanna Leonard Hill!

RhyPiBoMo Daily Lesson: Tuesday, April 29th
By Angie Karcher © 2014
Lesson 31

Let’s see how our Picture Book Cake turned out!

Yesterday, I shared a recipe with you on how to bake a rhyming picture book cake. I baked that cake today and thought I’d share a piece with you all…

I’ve been baking this cake for years but it has never turned out quite as well as it did today. I know the reason why…Because of all the poetry that I’ve studied in April. Those poetic elements have really made my cake rise higher than ever before. It is light on words, moist with rhyme and so rich with lyrical texture that I can’t wait to serve it up to an editor or agent.

Picture Book CakeBut, of course, it will be served to my critique group first!

This is the traditional story arc with a bit of poetic/rhyming technique thrown in for

us Rhyming Picture Book Cake Bakers!

This graphic is for you RhyPiBoMoers!

Please enjoy and promise to share it with other rhymers out there!

This is the classic picture book structure that has been handed out to me year after year at conferences and workshops. It hasn’t changed from this format in my 12 years of writing for kids. I think the reason it hasn’t changed is because it works! Of course, your book doesn’t need to have each item exactly on the page where this is suggested. It is merely a guideline for you to base your work on. Unfortunately it doesn’t help us rhymers with our specific goals in writing rhyming picture book manuscripts.

Page 1:             Half Title Page
Pages 2-3:       Full Title Page
Page 4:             Dedication
Page 5:             Intro Main Character, Setting, Problem, Point of View, Voice
Pages 6-7:       Deepen Awareness of Problem and Character
Pages 8-9:       Main Character’s First Attempt to Solve Problem
Pages 10-11:    Result
Pages 12-13:    Things Get Worse!
Pages 14-15:    Main Character’s Second Attempt to Solve Problem
Pages 16-17:    Result
Page 18-19:     Things Get Worse!
Pages 20-21:   Main Character’s Third Attempt to Solve Problem
Pages 22-23:    Result
Pages 24-25     Black Moment: Things Are at Their Worst!
Pages 26-27     Main Character Understands (Inner Climax)
Pages 28-29     Main Character Acts (Outer Climax)
Pages 30-31      Solution Works!
Page 32:            End with a Surprise or Twist

The thing that is missing from this wonderful list is the rhyming aspect. That’s because this is such a specific area that we have chosen and no one has created a list for us that includes the rhyming aspect of the picture book. Not that I’m aware of anyway…and I’ve been looking.

I have created another visual that adds all these elements together so you can ensure success with the picture book guidelines and the poetic devices necessary to write a superb rhyming picture book.

RhyPiBoMo Revision Post its

This sticky note visual includes everything you need to write a rhyming picture book. The orange notes are the rhyming/poetic elements and the rest of the notes include everything you need to write a traditional picture book…add this rainbow of notes together and you have a pretty good device
to help with writing rhyming picture books!

Start at the upper left corner and move down and over to the right gradually and you will find yourself at the bottom right with everything you need. There is not a definite order of things. I prefer this flowing list rather than a definitive list because we all have different processes. When I use a revision checklist, I never follow it in the order it is written. You probably don’t either. As long as you get to the bottom right with a rhyming picture book that is ready to submit…that’s the goal.

The Rule of 3’s

The rule of three is an old writing technique that is still around today. It is believed that things that come in threes are more effectively understood, enjoyed and remembered. It is a pattern that helps us process the information. (write this down)

For example:
The 3 Pigs
The 3 Stooges
3 Billy Goats Gruff
Goldilocks and the 3 Bears
The 3 Blind Mice
The 3 Muskateers

Slogans/famous quotes and phrases:
Go! Fight! Win!
Life, liberty, and the pursuit of happiness
Government of the people, by the people, for the people
Friends, Romans, Countrymen
Blood, sweat and tears
Location, location, location
Faith, Hope and Charity
Mind, body, spirit
Stop, Look and Listen
I came, I saw, I conquered

I say if it’s not broken…don’t fix it! So I highly suggest that you apply the rule of threes in all your writing, especially in your story arc concerning the conflict, the common use of beginning, middle and end and when you give examples.

Writing Prompt: Use the Bake a Picture Book Cake graphic and the Revise Rhyming Picture Books graphic and apply them to your work-in-progress.

Okay, now do everything else on the pledge for today and don’t forget to comment on today’s blog post!

RhyPiBoMo Pledge

RhyPiBoMo PledgeRhyPiBoMo Pledge Please comment ONLY ONE TIME below for a chance to win today’s prize! Prizes will be drawn by Random.com next Sunday for the previous week. To be eligible for a prize you must be a registered participant and comment after each days lessons.

96 thoughts on “Rhyming Picture Book Cake for Everyone! Tuesday

  1. Enjoyed your post today about the author because my son says I should listen to music more to help my natural rhythm. Also liked the PB structure with the added rhyming bulletin board.

  2. Susanna explains it so well and I love her example of stresses and syllables and picking one type of rhyme ot practice with. Thank you too Angie for the great checklist!

  3. Susanna, you crack me up. “Enjambment is some kind of raspberry sauce” – HAHAHAHA! You are one of a kind and we love you! And you are also a fabulous rhymer and poet, so come out from behind the dessert table, wipe the chocolate off your chin, and take a bow. Loved this post!

  4. Susanna, you crack me up! I won’t be able to think of enjambment again without craving hot toast with butter and raspberry jam. 🙂

  5. Thank you Susanna, what a great post! and way too funny…”Caesura? I’m pretty sure that’s a hairstyle popularized by Julius and Augustus.” I just received my copy of Airplane Flight! Perfectly timed to go with your wonderful advice!
    And Angie – LOVE that dashboard visual! An arc in an arc;)

  6. Susanna you sneaky sally hiding behind the dessert after your “see it’s easy!” Well, I shouldn’t be surprised because you make running an amazing blog and all those fun contests look easy too 🙂

  7. Susanna, You give me hope. After a month of trying to learn all these techniques from fantastic writers, it is encouraging to get advice from someone who feels rhythm in her soul. Thank you for your delightfulost. Thank you Angie for your cake and advice. It is very useful.

  8. Oh my goodness
    Let’s all make
    Rhyming stories, piece of cake! (twinkle, twinkle…..)
    Well not really a piece of cake, but what a great post!!! Singing with you, Susanna, while enjoying the whole cake, Angie. I don’t mean to be a hog, but just a piece of the cake isn’t quite right! Thanks and more thanks.

  9. I’m an accidental rhymer too. Been doing it since I was a freshman in High School. It just happens. I remember my parents saying when they got their first camera in the early 1950’s they took wonderful photos until someone taught them about all the dials on the camera. I was concerned that would happen to me this month. With all the technical information, would I lose my rhyming groove? But I’m still waking up in the morning with rhyme in my head so think I’ll be okay.

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