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Research Review - Final – Feb. 26, 2013

Intravascular Diagnostic Procedures and Imaging Techniques Versus Angiography Alone in Coronary Artery Stenting: Comparative Effectiveness Review

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Archived: This report is greater than 3 years old. Findings may be used for research purposes, but should not be considered current.

Structured Abstract

Several intravascular diagnostic techniques provide detailed information regarding the narrowing (stenosis) of the lumen of coronary arteries. They are increasingly used in addition to angiography during coronary artery stenting.

To systematically review the comparative effectiveness of intravascular diagnostic techniques versus angiography alone in patients with coronary artery disease who are undergoing percutaneous coronary interventions for the following objectives: (a) to decide whether a coronary lesion needs to be stented; (b) to guide and optimize stent deployment; (c) to assess whether stent placement was successful; and (d) to evaluate the factors influencing the diagnostic techniques' effect on outcomes.

Data sources

MEDLINE®, Cochrane Central Register of Controlled Trials, recent conference proceedings, and

Study selection

We included studies of any design and duration of followup, without any language or sample size restriction. We excluded studies that did not directly compare the use of an intravascular diagnostic technique with angiography alone or another intravascular diagnostic technique to decide whether to stent or to guide coronary artery stenting.

Data extraction

We extracted details on study population characteristics and results, and assessed studies for risk of bias. We evaluated therapeutic decisionmaking outcomes, intermediate outcomes, and patient-centered outcomes. We appraised strength of evidence primarily based on studies rated as having a low or medium risk of bias.

Data synthesis

In total, 37 eligible studies evaluated two of the intravascular diagnostic techniques, namely fractional flow reserve (FFR) and intravascular ultrasound (IVUS). There is a moderate strength of evidence (drawn from one randomized controlled trial [RCT] and one nonrandomized study) that the use of FFR, as compared with angiography alone, supports the following: (a) FFR is effective in helping to decide whether intermediate coronary lesions (defined as 50% to 70% stenosis) require stenting; (b) FFR confers a lower risk of the composite endpoint of death or myocardial infarction (MI) or of major adverse cardiac events; and (c) FFR leads to fewer stents implanted and reduces the cost of the procedure. Regarding the comparison of IVUS-guided stenting and stent placement guided by angiography alone, there is a moderate strength of evidence (drawn from 9 RCTs and 22 nonrandomized studies) that supports no significant difference between the two approaches in mortality or MI, but a significant reduction in repeat revascularizations and restenosis with IVUS-guided stenting. There is insufficient evidence concerning the use of intravascular diagnostic techniques immediately after percutaneous coronary interventions to evaluate the success of stenting compared with angiography or for direct comparisons between intravascular diagnostic techniques. There is a moderate strength of evidence (on the basis of one large nonrandomized study) that sex, diabetes mellitus status, lesion length, and reference diameter among those undergoing IVUS- and angiography-guided stent placement had no significant association with major adverse cardiac events or its individual components. There is insufficient evidence to evaluate the comparative effect of intravascular diagnostic techniques other than FFR and IVUS.

Studies evaluating FFR and IVUS were limited by incomplete outcome reporting, heterogeneity in outcome definitions, infrequent enrollment of women, and a lack of data on patients with left main coronary artery disease or acute MI. The evidence for FFR was derived from trials that focused on patients with lower grade angina or those with nonischemic intermediate coronary stenosis. The majority of the IVUS trials were conducted before 2000, a particularly important limitation given the rapid pace of technological advancement in this domain.

There is a moderate strength of evidence that the use of FFR (as compared with angiography alone) to decide whether or not to stent an intermediate coronary lesion confers a lower risk of composite endpoint of death or MI, or of major adverse cardiac events; leads to fewer stents being implanted; and reduces procedural costs. There is a moderate strength of evidence that the use of IVUS (as compared with angiography alone) to guide optimal stent placement reduces repeat revascularization and restenosis, but does not affect mortality or MI. Future studies will need to focus on women and on patients with more severe coronary artery disease, and to evaluate longer term (on the order of years) patient outcomes to better appreciate real world effectiveness. Stenting low-risk lesions may lead to additional invasive tests or treatments that could adversely impact long-term outcomes. Further research is also needed to evaluate the use of hybrid and novel intravascular diagnostic techniques.


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The advantages of living abroad

Written by lynn holmgren
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The advantages of living abroad
(Lynn Holmgren)

Whether overseas as a student, military personnel, foreign service worker, volunteer or retiree, the advantages of living abroad are numerous. The increasing number of Americans living abroad -- recently estimated at 6.6 million by the U.S. Department of State--demonstrates the appeal of living in another country. (See Reference 1)

Other People Are Reading

Advantages for Children

For adults, the decision to live overseas is usually voluntary. For children in tow and born abroad, the circumstances that subsequently alter the shape of their lives are more often involuntary. Dr. Ruth Hill Useem, Professor Emeritus of Sociology and Education at Michigan State University, conducted a study on Adult Third-Culture Kids (ATCKs) in the early 1990s that revealed that people who spent at least one year or more of childhood outside of their home country were likely to have a higher level of education, and more advanced problem-solving skills and foreign language abilities. If globalisation and international understanding are any markers, these skills clearly put ATCKs at an advantage. Large numbers of ATCKs remain in contact with people from other countries, are involved as volunteers with international organisations, and expose their own children to the message that diversity is something to be celebrated.

Advantages for Young Adults

The number of Americans studying abroad--which has risen 150 per cent since the late 1990s--continues to set records, a trend made popular by the advantages of international education. IES Abroad, one of the nation's oldest, largest, and most reputable study-abroad providers, released a survey in 2009 covering one decade of their study-abroad alumni that touts the advantages of the experience. The majority of students claimed to have increased confidence, maturity, understanding of their own cultural values and biases, and acquired skills that influenced their career path.

Advantages for Adults

The advantages of living abroad as an adult are manifold. Famous artists and authors such as Pablo Picasso, Rudyard Kipling and Ernest Hemingway spent years dwelling abroad, causing many to speculate about the connection between creativity and living abroad. A May 14, 2009 article in "The Economist" cited a study in the Journal of Personality and Social Psychology that validated this link through two tests of creativity. The study concluded that those who had lived abroad were more likely to arrive at or negotiate creative solutions. No matter if the motive is educational, financial or personal, living abroad can provide a wider sense of the world and maybe an idea for a novel.

Living abroad is not difficult, and many people take advantage of the opportunity to work and live overseas at some point in their lives. Education, international understanding and confidence are skills that can be gained from the experience.

There are publications that cater to people wanting to live, study and work abroad. "Transitions Abroad" ( is a magazine that shares personal essays, insight and opportunities. "Abroad View" ( is an online magazine specifically for students studying overseas.

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24 February 2017
What will be Leung Chun-ying's next move against Sixtus Leung and Yau Wai-ching? Photo: Bloomberg, HKEJ
What will be Leung Chun-ying's next move against Sixtus Leung and Yau Wai-ching? Photo: Bloomberg, HKEJ

Upcoming Legco by-election will be an Armageddon

Things have taken a sudden and nasty turn over the past week as far as the oath-taking saga is concerned.

Since what is done is done and we can’t turn back the clock, I prefer not to waste my time playing Monday morning quarterback.

Rather, I would like to look at the future and focus on the by-election following the disqualification of the Youngspiration duo.

In my opinion, the upcoming by-election could amount to an even more profound and decisive referendum than the Legco by-election back in March on whether our city should seek full independence.

In other words, there is still a silver lining to the removal of Sixtus “Baggio” Leung Chung-hang and Yau Wai-ching from office, as the by-election they trigger can provide a very good opportunity for the people of Hong Kong to make their voices heard and show their support for the pro-independence cause.

The latest interpretation of Article 104 of the Basic Law by the National People’s Congress Standing Committee (NPCSC) did not mention anything about the by-election, nor did it say in no uncertain terms that those who have been disqualified cannot run again.

On the surface it might appear to be a sign of Beijing’s leniency, but in fact it is not at all, because the party officials in Beijing know very well that Leung and Yau won’t stand the slightest chance of getting elected in the by-election under our proportional representation system.

Nor did the NPCSC’s interpretation touch on the legal grounds based on which Edward Leung Tin-kei representing the Hong Kong Indigenous was barred from running for Legco earlier, perhaps because Beijing didn’t want to be too explicit about its power to make the SAR government vet Legco election candidates based on their political ideology in order to limit the scope of this interpretation and minimize public backlash.

From Beijing’s point of view, that can easily be done without having to invoke any law, such as by means of demanding that all candidates sign a written statement pledging to uphold the Basic Law.

So is the Leung Chun-ying administration likely to bar the Youngspiration duo from running in the upcoming by-election the way they barred Edward Leung from running in the September election?

I don’t think so, because it doesn’t have to.

Like I said, under the proportional representation system, the pro-independence faction, which only has a 20 percent public support, stands absolutely no chance of winning.

Besides, it remains a big “if” whether the duo will be taking part in the by-election, as I believe the washed-up and crooked pan-democrats would do whatever they could to talk them out of running so that they could send their own candidates to take their places.

In exchange, they might promise to root for them in the next Legco election.

Whether or not the duo will run again is not the key issue here. Instead, what matters most is that the by-election will turn out to be an Armageddon between pro-Beijing and pro-independence forces, and the result of the election will no doubt serve as an unmistakable indication of public opinion on this critical issue.

As far as I am concerned, my vote will definitely go to Sixtus Leung if he is going to run again – partly due to my support for the demand of the post-Occupy generation for self-determination, and partly out of my indignation at the NPCSC’s interpretation.

Like I said before, begging will never work when it comes to fighting for democracy, and submission in the face of tyranny will only result in more oppression.

Very often, a slave only has himself to blame for remaining a slave, and likewise, the people of Hong Kong will probably only have themselves to blame if Leung Chun-ying gets re-elected.

This article appeared in the Hong Kong Economic Journal on Nov. 8.

Translation by Alan Lee

[Chinese version中文版]

– Contact us at [email protected]

HKEJ columnist

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• March 6, 2014

    World Book Day is 6 March in 2014 throughout Britain and Ireland. In other parts of there world it is sometimes marked in April.

  • February 11, 2014

    Pioneering Lutheran theologian, anti-Nazi resister, educator, ecumenist, poet, pastor and martyr Dietrich Bonhoeffer was born on 4 February 1906. Ekklesia co-director Simon Barrow introduces an important new book which challenges the myth of his abandonment of peacemaking and recovers his call to the way of Christ.

  • June 13, 2011

    A widespread “everyday atheism” requires a new understanding of what it means to be the church, according to Berlin theologian Dr Wolf Krötke.

  • November 3, 2010

    Contrary to the impression given by the Anglican Covenant, faithfulness to Christ crucified means being willing, if necessary, to refuse to conform, and instead to take a stand alongside One who was “numbered with the transgressors”, says Savi Hensman. Communion is misconstrued when it is translated as imposed institutional conformity.

  • June 23, 2010

    Peace activists in Australia are continuing to put their bodies on the line in opposing their country's military involvement in Afghanistan, after Christian peacemakers scored an important moral victory.

  • April 2, 2010

    A group of peace activists inspired by the example of German theologian Dietrich Bonhoeffer have successfully infiltrated a secret Australian military base on Swan Island.

  • June 28, 2009

    Public life demands ‘tough’ corporate attributes rather than what it labels ‘soft’ personal ones – like love and gratitude. Simon Barrow argues that the communal cultivation of loving relation is needed to help redirect the official anonymity of the social order.

  • October 13, 2008

    Protestants in Germany are recalling the life of George K. A. Bell, an Anglican bishop who opposed the Nazi regime of Adolf Hitler but also sharply criticised indiscriminate bombing of German cities during the Second World War.

  • August 29, 2008

    A pioneer in the global study of the phenomenon of fundamentalism, commentator and scholar Martin E. Marty reflects on the changing patterns of religious life as they have impacted Europe recently.

  • June 26, 2008

    Have many American Christians forgotten the distinction between discipleship and partisanship, asks Martin E. marty, looking at some authors who unpack the complex relationship between Christian faith and political reality.


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Established in 1975, Eland Cables is a supplier of power, data, instrumentation and control cables and cable accessories to the world's most demanding industries and to some of its most prestigious projects. Our reputation is built on an unswerving focus on quality, technical expertise and customer service.

Our focus on quality has resulted in our in-house specialist cable testing facility securing the ISO 17025 accreditation. This certifies the competence, impartiality and performance capability of our laboratory and its evaluations. In turn, it means peace of mind for our customers with regard to the quality of the cables they source from us.

Expert tecHnical support

Our highly-qualified technical team is on hand to provide technical support with all aspects of cable selection, technical specification, regulatory requirements, and bespoke cable design and manufacture.

Complete Cable Solutions

We are a key contributor to projects in over 100 countries every year, adding value through comprehensive technical support, reliable logistics, innovative solutions, and a customer-centric approach.

The Cable Lab®

UKAS-accredited specialist cable testing laboratory

About Eland Cables

The Cable Lab® our in-house cable testing facility, is UKAS-accredited to ISO 17025, which is the single most important standard for calibration and testing laboratories around the world. Accreditation to this international standard demonstrates our laboratory's technical competence and the accuracy of its results.

For our customers, it means peace of mind. They can have full confidence in the quality of our products and can demonstrate due diligence in selecting their cable supplier.

Our customers can also rely on the Cable Lab's services for an independent, objective and comprehensive quality assessment of cables procured from third parties.


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Having problems with your Dell OptiPlex GX280 PC Desktop ?

Dell optiplex gx280 won't boot up

\015 I installed a new 650 watt power supply in my dell gx280 and now when i turn it on it says no boot device available, i also temporarily took out the floppy drive to get at a part in case that's the problem, cause i know that the floppy drive is part of the boot process. but that doesn't make any sense because my computer has booted fine for years with no disk in the floppy drive\015

Answers :

You either have the boot priority in the bios off or you have improperly cabled your hard drive . perhaps you set it to boot to cd while installing the operating system and forgot to change the order back.
\015\012 The floppy drive does not have to be present for the system to boot (if set to "not installed" in bios)
\015\012your boot devices are your cd/dvd rom and your harddrive.
\015\012Seeing as you've recently replaced the power supply , ime assuming you didnt dismantle the whole computer , just the power leads coming from the power supply, which means you only moved power , not data cables.
\015\012This would be the first thing to check -- power to the harddrive and cd rom, the 4 pin connector that sometimes connects to the motherboard and any data cables you might have bumped while changing the power cables. check these things and post here again.
I'm no expert, but maybe my experience will help someone. I had this same problem- replaced the PSU in my Optiplex GX280 Mini Tower and got the "No boot Device" message. I found that I had to go into set up and check the drive settings- the hard drive and cd rom drive were set to off. I don't know if switching out the PSU caused the change- or maybe because I also changed the battery, but my suggestion is Check your drive settings!
Repair Help & Product Troubleshooting for Dell OptiPlex GX280 PC Desktop

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Dell gx280 sff show orange light when turned off.fans running though My Dell Optiplex GX280 makes a lot of nice and fails to boot. It also displays orange lights and just hangs, it does not even boot the BIOS

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When your computer hardware appears to power up okay, but the Windows XP operating system won't boot properly, you have to begin a troubleshooting expedition that includes getting into the operating system, determining the problem, and then fixing it ... Dell OptiPlex GX280 PC Desktop
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Having problems with your IBM ThinkPad T20 2647 Notebook ?

IBM laptop gives CRC1 error

\015 My IBM laptop gives CRC1 error. I have tried almost every thing. But could not get rid of this problem. Can any body help me in this matter ?\015\012\015\[email protected]\015

Answers :

Certain files for software have been moved or deleted the software needs to be reinstalled...norton antivirus on one of my machines used to do this (crc fail/error/not found)
Repair Help & Product Troubleshooting for IBM ThinkPad T20 2647 Notebook

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Suggested Questions/Answers :

IBM laptop gives CRC1 error

Certain files for software have been moved or deleted the software needs to be reinstalled...norton antivirus on one of my machines used to do this (crc fail/error/not found) ... IBM ThinkPad T20 2647 Notebook

ERROR 0175: Bad CRC1, stop POST task message

... IBM ThinkPad A30 Notebook

IBM R30's CMOS Battery Replaced but still trouble

Probably itz either minor case of software corruption/improper ground/cpu fan..or major case of faulty or defective main board/ram/addon/daughter cards....plz do check the following as in order:..the Hardwa ... IBM ThinkPad R30 2656 Notebook

Error 0175 bad crc1

Numeric error codes - ThinkPad General From IBM Web Site\015\012Notes:\015\012· The most likely cause is listed first.· A numeric error is displayed for each error detected in POST or s ... IBM ThinkPad T20 2647 Notebook

Error loading operating system

The Thinkpad T23 is old, and would not worth fixing. Save your money on a new one.\015\012The problem with your laptop is that the hard disk or the disk controller has failed and therefore cannot find the operating system on the hard disk. The ... IBM ThinkPad T23 Notebook

Ibm t22 thinkpad laptop error 0175 crc1

Ok hm...\015\012\015\012Sounds expensive, I'm afraid! ... IBM ThinkPad T22 Laptop

ERROR 0175: Bad CRC1, stop POST task message Been using my IBM a30 laptop for some months but was surprised to get this error when i tried putting it on this message pops up ERROR 0175:BAD CRC1 STOP POST TASK CPU=Inter(r) mobile mobile intel(r)pentium(r)3 processor-mprocessor 866mhz 638k system ram passed 126m extended ram passed 512k cache sram passed system bios shadowed video bios shadowed umb upper limit segment address:dcoo fixed disk 0:ibm-djsa-210 atapi cd-rom:sony cd-rw crx700e mouse ini

You obviously didn't read the problem carefully. The machine won't boot, so there is no command line. I have the same problem with a T23. It might be the CMOS battery that needs to be replaced. ... IBM ThinkPad A30 Notebook

MY laptop beep twice and flag error code Bad CRC1, stop POST task

Ibm 2373 beep ram error ... IBM ThinkPad T20 2647 Notebook

IBM Laptop A22e Display an error 0175

The CRC error (POST = power on startup test) on boot up refers to the BIOS settings. This could be cause by a near flat BIOS battery and it needs to be replaces. If it is not the battery you need go to the BIOS to correct any faulty settings. ... IBM ThinkPad A22e 2655 Notebook

IBM Thinkpad 600e (2645),error 189 and could not installing win98

Usually this means a hardware failure. I would suggest reseating the CMOS battery overnight to reset the system. Also you might want to replace it as well. It could also be more serious such as a motherboard component failure. \015\012\015\ ... IBM ThinkPad 600E 2645 Notebook

IBM ThinkPad 600E problem

I turn on the laptop, after a few second it gives me an 08611 errror. what does it mean? ... IBM ThinkPad 600E 2645 Notebook

Does any know how to fix a CRC1 error on an IBM laptop? pls help.

If you get this for a CD/DVD disc, your disc is bad...if you get this error on your hard drive, it means your drive is failing.\015\012\015\012try to backup your data if possible and you will need to replace and reinstall all software. if ... IBM ThinkPad T20 Notebook

Crc1 error ibm laptop on booting it, it brings this error bad crc1 error

That means that the data is corrupted somehow. It could be a damaged or bady written CD/DVD, or it could be data corruption on your hard drive, depending where the program is.If it's on the hard drive, reinstall it. If it's the CD/DVD, you will ... IBM ThinkPad T22 2647 Notebook

IBM Thinkpad 2647

This may be a serious problem, and then it may not be. This is going to be a problem with the system board programing. First thing is go into the bios at start up and load set up defaults, or set the bios to default. If this doesn't work, then use an ... IBM ThinkPad A21m 2628 Notebook

Ibm notbook. how will i solve "bad crc1, stop post task. with an error code 0175?

The POST error code 0175 refers to a CRC (cyclic redundancy check) reading from the EEPROM chip, that data is corrupted, most likely a faulty EEPROM chip. This is a motherboard problem and cannot be fixed except by a motherboard replacement. This is ... IBM ThinkPad A21e 2655 Notebook

HI http://www.notebook-drivers.com/ViewDownloadUrl.asp?ID=86457&brNum=3&show=0 ... IBM ThinkPad T60 Notebook

IBM A22e laptop Bios problem

... IBM ThinkPad A22e 2655 Notebook

PC won't run: Fan Error

This is a self test that is checking the fan and finding that it is in error. You might have the fan damaged or else just stuck with dust inside and therefore to protect from over heating the laptop gives you this error.Please check if t ... IBM ThinkPad T40 2373 Notebook

My ibm thinkpad r51 is not starting up just keeping giving me error message and it doesn't recognize the hard drive in boot. I have to take the battery to stop the system trying restart the window again and again.

It appears the hard drive is faulty.\015\012Does the hard disk LED flash when the laptop boots up?\015\012Go into the BIOS configuration and see it the hard drive is detected, (then Startup - Boot - and look at IDE HDD0 it should list the ... IBM ThinkPad R51 Notebook

I am trying to get an IBM T42 laptop up and running. I started it up with the rescue and recovery CD in the drive. It showed the bars on the bottom of the screen and seemed to complete the process but then I got a blue screen (I did not write down the exact error message, but it had something to do with an error in windows and was shutting down to avoid damage to the machine). On restarting, it gets through the memory check just fine and then tells me a bunch of stuff, the last line of which

Hello, Diver.I'd suggest doing a hardware diagnostic check, especially if you experienced errors in the past that may be hardware-related.Regarding your operating system, if you have Vista, give this a try:you can ... IBM Lenovo ThinkPad T60

Re: Errors being experienced with the ACER ASPIRE 5100-5758, OS VISTA. Error dealing with BUS:06, DEVICE:04, FUNCTION:00 AND ON TO FUNCTION:03

Hi, Nice report. We don't see these too often. You've had quite a few tech inclined people on your machine. My first hunch was memory timings and that could still be the problem. However, there is also memory on the display ad ... Acer Aspire 5100 Notebook

I just dug my old 2635 out from under the couch and having the same issue. I'm wondering if the internal battery needs replacing - this would give power to the system ROM where the date and time is held. I'll let you know if I find anything. ... IBM ThinkPad 380ED

IBM a20m ram issues

If they are compatible but your machine isn't happy with them, it sounds like they're faulty. Return both sticks to the retailer and ask them to replace both, just in case they replace the good one and give you the faulty one back. ... IBM ThinkPad A20M Notebook

Toshiba 5205-s503 won't start up

In my 15 year career in electronics, among other companies, I have most notably worked for United Technologies as Test Engineering Technician and as an Electronic Failure Analysis Technician for Jabil (Circuit.) I am unemployed due to US electronics ... Toshiba Satellite 5205-S503 Notebook

My old buy IBM thinkpad Laptop not display after automatic closed. and massage as:Eorr-0175 Bad CRC1,stop POST task. So, pl, give me guide to display same.

If I get you right, Your display doesn't turn on after Standby/Hibernating ! There could be several causes to that. 1. Old/faulty display Driver!2. Old Bios3.Graphics card failure!I would begin with downloading and flash ... IBM ThinkPad T23 2647 Notebook
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Having problems with your Ubi Soft Entertainment 02B Game PC Assassin's Creed Director's Cut Edition for Windows ?

Trouble with playing the game

\015 I ahve installed the game assassin's creed in my laptop which is a pc game in vista.all the installation and requirements is met.when i click play a message comes "the game has encountered a problem" what do i do? can anyone suggest any solution regarding this.\015

Answers :

Hello vamshi_yadat,

You will need to verify that your laptop can handle the requirment's of the game. When it gives you an error of "encountered a problem" It can be anything from a driver to a compatibility issue with your video card or memory.

Post back with more info for further help. Thank you for trying Fixya!
Repair Help & Product Troubleshooting for Ubi Soft Entertainment 02B Game PC Assassin's Creed Director's Cut Edition for Windows

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ER Game error

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Custom Building Gaming Question

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Controller detection I'm having some trouble with this PC con gamepad. The game that I'm trying to play it with doesn't seem to be detecting the controller. The game is actually just a demo version and that may be why. I am not totally sure though. I'm also not sure if I'm supposed to install anything so my mac can actually recognized that I've plugged it in. The game is called Jedi Academy and I don't know if the game even supports a device such as this. Any help at all would be appreciat

Jedi Academy cant play on a controller cause ive tryed to play that game before with a controller and it dont work, also look to see if that controller is MAC compatable and maybe update the driver for the game pad. ... Mad Catz PC Con (728658544263) Game Pad

Im having trouble playing with my mate and sister but we are all in the same house on age of empires rise or rome how can i play with them?

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GTA IV multiplayer issues

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Umar Hills wont load.

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Crashes to windows after playing about 5 minutes

Most likely the issue you are having is your computer is under powered to run both Vista Home Premium and the game. Vista is heavy on the resources and since you are running Vista Home Premium you will need more then some running the Basic version. ... Ubi Soft Capitalism 2 for Windows

I just purchased a new game, Spore and it wont play

Try installing the video card driver from here. It will at least give you the latest driver version. As far as the monitor does it turn itself off after being left unused for a while or randomly play up?\015\012Have a look at the power settings ... HP Compaq Presario SR1610NX (ED865AA) PC Desktop

I'm having trouble with the shockwave game supermarket mania, it was playing fine and now i try and play and in just get me to the exit screen. I would like to uninstall shockwave so i can reinstall it.

START - CONTROL PANEL - ADD REMOVE PROGRAMS THEN ....\015\012First make sure you UNINSTALL the SHOCKWAVE GAME from the System... then make sure you don't already have shockwave installed on your PC. If you do... REMOVE IT! Reboot the system wit ... PC Desktops

Trouble with playing the game

Hello vamshi_yadat,You will need to verify that your laptop can handle the requirment's of the game. When it gives you an error of "encountered a problem" It can be anything from a driver to a compatibility issue with your video card or m ... Ubi Soft Entertainment 02B Game PC Assassin's Creed Director's Cut Edition for Windows

Acer Aspire Shuts down when I play my on-line game

A notebook can only shut down if the processor is getting HOT that is by itself. I can timagine its a virus because you said you formatted it?. You keep maintaining that it keepsshutting down. to me thats the CPU because its getting too HOT>\015 ... Acer Aspire 5100-5022 Notebook

Having trouble playing game

You might need to update you version of DirectX by going to the microsoft site, or make sure that the 3D accelleration is enable in DXDIAG.\015\012If using XP go to Start>Run (on the right hand side) and type in dxdiag then press enter. Whe ... Eidos Interactive Computer Games

I am having trouble downloading this game on my computer

Friend.the thing u may not have the original key code.if u have active internet connection and membership oon any game site u can download from there.or create membership in fileplanet.com or usenext.com.the best thing is u c ... 2K Games Mystery P.I. The Lottery Ticket for Windows

It installs but wnt play

Your computer probably can't handle the game. Make sure your Operating System meets the requirements of what the game calls for. If it does and it still does not play, call the Maker of your game, and they should be able to trouble shoot it. Best of ... Got Game A Quiet Weekend in Capri for Windows

DVD Drive Troubles

Ur drive format can also be a reason for not reading the disk .. Try them on some other brand drives. Sony drives sometimes do not read some of the disk ... PC Desktops

"Please Insert Disk 2"

Try cracking it.. dont know what crack is? :1. insert disk..2. open my computer and find the drive where the disk is inserted,3. right click on the selected drive and in it find the folder crack.4. copy the image o ... Macplay Baldur's Gate II: Shadows Of Amn for Mac

Is it my computer or my game?

Ok uninstall everything with that game if it is a laptop make sure you fully turn it off and take the battery out of it and reinstall new version lala linda ... Toshiba Satellite L45-S7409 Notebook

Thank you very much for showing concern in my problem. I recently noticed that the width cut from sides changes on changing refresh rate. also, screen gets shortened everytime i play games like counter strike. for eg., after playing game for 5-6 times and exiting the game screen size reduces by about 2 mm or so. About replacing the parts, i think i will get it by some technician but it would be handy if i know what is faulty or else the technician would charge a kings ransom by

Use the schematic diagram near the end of the service manual. Ask your tech to check the components around the C429, D409 and L401 area. Alternately, follow the trouble shooting chart of 5-1-6 and/or 5-1-7 of the same manual. ... Samsung SyncMaster 753S 17" CRT Monitor

Producr assistance In November of 2007 I purchased an eMachine model number T5230 desktop pc. My son is having trouble loading some of his games and I would like to know exactly what I need to purchase to increase the speed and memory of this particular model. Thank you. [email protected]

Many of the newer machines for sale now unfortunatly do not include a seperate and powerful video card. The machine comes with an internal video card that shares the machine's memory for video loads; iy is built into the motherboard to reduce the sel ... E-Machines eMachines Desktop PC

COD4 Computer Version Troubles

The error message you got would show up in the following scenarios:1. DirectX not up-to-date.2. Video card drivers old.3. The game being played with a not supported video card.Check for the above mentioned and it should ... Computer Games

Feed? hi i play a virteal realty game at marapets.com i got a new computer and tryed to go to this game site and it will come up then when i go to sign on it kicks me off.so i thought it was the site having trouble but i hooked my old computer up and got right in .i down loaded java and tryed it too please if any one can help.today when i tryed it it sayed there was no feed on the web site.what do i do next?

I would suggest that you send an email to the game company, since it sounds like the game computer dumped a piece of code or else a cookie onto your system and this is what's needed for you to log in. Unless the game server used your cpu's serial num ... Compaq Presario 5000 PC Desktop

Hello i have a toshiba l305-s5911. Im having trouble when playing PC games when i alt tab from them the game freezes and says not responding. I have looked for drivers for it no luck. This doesnt just happen in one game but most of my games. seems to be the ones with the direct x. if anyone can help that would be great. if it helps i have vista

The Vista Direct X engine is known to be finicky at best and have issues, especially when dealing with minimizing games. I would recommend going to the Microsoft website and making sure you have the most up to date Direct X for your system. You can ... Toshiba Satellite L305-S5908 Notebook

Plugging in Mic ceases sound playback

The drivers are working, but you apparently have a non asynchronous driver, meaning it either records, or plays, but has trouble doing both.Gamers usually like their sound a bit beefier than the standard AC97 chip common with mainboards c ... PC Desktops
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Mentor Graphics and Digi-Key bring low-cost EDA tool for PCB design

May 22, 2014 // By Julien Happich
Electronic components distributor Digi-Key Corporation has joined forces with Mentor Graphics Corporation to create a unique concept-to-prototype design tool targeted for green-field projects before transition to production.

Available from Digi-Key, the Designer Schematic product from Mentor Graphics addresses escalating demand from professional engineers for Electronic Design Automation (EDA) software at an affordable price point for new R&D projects, while facilitating access to the latest parts.

With Designer Schematic, Mentor Graphics is extending its range of PCB development solutions, now serving individual engineers working on conceptual projects, the desktop market with PADS, and the extended enterprise with its flagship Xpedition flow.
The Designer Schematic tool is scheduled to launch early this summer, at an unprecedented sub-$300 price point. Engineers will gain the benefit of first-class design tools, as well as increased freedom to use new components with error-free EDA representation, as they are released, providing direct paths to quick-turn PCB layout and manufacturing services.

Visit Digi-Key at


text:
Experience The Finest in Skin Care

Biologique Recherche

Seconde Peau Facial

Welcome to Elite Skin Care! Owner and Master Esthetician Liza Wong custom-designed this beauty sanctuary and set the gold standard for women to indulge in the ultimate facial experience in pure comfort, privacy and luxury. All services are performed in a tastefully-appointed setting.

Every facial is a work of art where the esthetician becomes a symphony composer. Creating a masterpiece involves key elements - skills and a level of experience, the selection of fine products, usage of advanced instruments, mood and ambiance - are all necessary for perfect harmony. When synchronized with passion and mastery, the facial transcends the ordinary and becomes a truly creative expression.

Our facial treatments deliver unsurpassed results for clients experiencing acne, sun damage or sagging skin. The Elite Skin Care clientele includes female executives, socialites, and skincare connoisseurs who seek the highest quality treatments and products. Commitment to excellence is our forte.

Liza is known for her caring personality, attentive manner, sense of humor, and most importantly, her magical touch. She possesses a wealth of skin care knowledge and has curated an amazing array of highly effective products to treat a wide range of skin care needs and conditions. She personally attends to questions by phone or e-mail.

We invite you to explore Elite Skin Care today.

"Liza Wong was named as one the brightest stars in
Allure Magazine 2015 Best of Beauty Directory"


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Homeopathy for Health

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Product: Dental Balance Anti-Inflammatory 1 oz with 800 pellets
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No Picture Dental Balance Anti-Inflammatory is offered for teeth and gum support. Dental Balance Anti-Inflammatory restores balance to your gums and teeth. Dental Balance Anti-Inflammatory can help to relieve pain and discomfort.
Dental Balance Anti-Inflammatory is a blend of important remedies in a potency blend. All remedies are in 6C, 12C, 30C and 200C. Dental Balance Anti-Inflammatory includes Ac Cit; Ac. Cis; Aranea; Gingiva; Myosotis; Osteomylitis; Otitis; Reduce Inflammation; Kidney; Silicea. To help natural flora of the mouth, includes Staphylococcus Aureus and Streptococcus Fecalir in 6C potency. To help with jaw or dental pain, neuralgia, toothache, includes Hekla Lava in 30C potency. Hekla Lava is listed in the Materia Medica as acting upon the jaw and and offering support in issues of dental sensitivity, gum abscess, caries of the bone, abscess with facial swelling, and tooth decay concerns.

Dental Balance Anti-Inflammatory is offered as complementary alternative medicine (CAM). According to the government’s National Center for Complementary and Alternative Medicine (NCCAM), 38% of adults use complementary medicine. Integrative Medicine combines conventional and CAM treatments for which there is evidence of safety and effectiveness (http://nccam.nih.gov/health/whatiscam/). There are no contraindications to homeopathy, making homeopathy an ideal adjunct to your health plan. Our information is not intended to diagnose, mitigate, prevent, treat, or cure any symptom or disease as defined by the FDA.
Information on this kosher parve product.
Information on the manufacturing process for this product.
Dental Balance Anti-Inflammatory in a 1 oz bottle of 800 pellets with 265 doses. Pellets are sucrose base with trace of cornstarch.
Suggested dose is 3 pellets 3 times a day for symptoms. 3 pellets once a day for maintenance of good oral health.

  $21.99 Buy Dental Balance Anti-Inflammatory 1 oz with 800 pellets

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Pretty in Pink

Most Popular
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YYigal dress at Intermix.

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Mara Hoffman dress at Intermix.

Jay Godfrey dress at Intermix.

I'm having a major hot pink moment right now. I recently realized that I have not a single fuchsia-hued piece in my entire wardrobe and now I'm desperado for a little mini dress in the color to wear before the summer's out (one more month—unbelievable!!). It's a little Malibu Barbie, I'll admit, but it's cute and flirty and I just don't care.

I found these three at one of my favorite stores ever, Intermix.

Decisions, decisions. What's your take, ladies and gents? Cute? Or is it a guaranteed cheese-fest?

photos courtesy of

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• 13102959491

Wedding and events

El Paraiso Hotel Tulum

"Paradise is always where love dwells"

Jean Paul F Richter (1763-1825)

There are few places in the world as beautiful as the El Paraiso beach. It is a place you fall in love with and a place to fall in love at. It is a small piece of paradise on earth. A wide stretch of white sand, palm trees scattered along the beach and outstanding views of the infinite turquoise blue Caribbean horizon, creates the magic atmosphere at El Paraiso Hotel, making it the perfect setting for your dream wedding or a special occasion.

Together with Playa del Carmen Weddings, we have many years of experience organizing weddings and event, helping brides and grooms, family and friends create special moments and unforgettable memories. We understand that each individual is unique and therefore put great importance into organizing each wedding down to the smallest detail to make sure that all your expectations are fulfilled and exceeded. Our desire is to create your perfect day that represents who you are and to make your wishes come true. We do all the planning, preparation and execution, so that you can completely relax and enjoy your special day.

At El Paraiso Hotel we don’t just give you the perfect wedding or event – we give you a part of Paradise…

Please contact us for further information about ideas and planning of your special event or dream wedding in Mexico


text: Related Information for Josh Wink Josh Wink (a.k.a Winx, Wink, E-Culture, born Joshua Winkelman in 1970) is an electronic music DJ, label owner, producer, remixer, and artist. He is a native of Philadelphia, United States. A pioneering DJ in the American rave scene during the early 1990s, Wink was the most prominent exponent of the tribal forms of techno and house in the U.S. In 1995, he released several hits, including "Don't Laugh," "I'm Ready" (which hit number one on the U.S. Hot Dance Cl.. read more


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Understanding Drugs and Addiction - King's College London

Informação importante

How do addictions develop? How are they best treated and prevented? Explore these key questions with this free online course.

Informação importante

Instalações e datas

Início Localização
17 fevereiro 2017
07 março 2017
09 março 2017

O que se aprende nesse curso?

Understanding Drugs and Addiction, is also running in Chinese, starting 21 March 2016. To find out more and enrol, visit the course page.

We are all touched by addiction – personally, within our circle of family and friends, and within our community. Addiction and its related harms can be crippling for those affected and the people around them.

But how does addiction develop? What can we do to treat it? And what can we do to prevent it?

Explore how addiction develops

In this free online course, we’ll explore how addiction develops, looking at the environmental, genetic and personal risks involved.

We’ll examine what happens when a drug enters your body and your brain, how your brain changes, and how this process can make recovering from addiction such a challenge.

You’ll learn how we can best treat addiction, and how national and international policies help limit the harms from addiction.

Meet experts in addiction science and treatment

King’s College London is a world leader in the science and treatment of addiction. Educators on this course are drawn from a variety of disciplines throughout the university, and work together to understand and respond to addiction.

Each week, we’ll be joined by some of the world’s leading scientists, who will present cutting edge neuroscientific research - research that will lead to a greater understanding of how addiction develops and how we can treat it most effectively.

By understanding addiction, we can shed light on the greater issues of self-control and choice. Indeed, we will develop a greater understanding of ourselves.


text:
Emerald Sanctuary Belly Dance Retreat is an annual belly dance retreat in the high desert of Central Washington, usually held the last weekend of August (before Labor Day). Regional and local instructors offer an exciting range of workshops for the beginner to the seasoned dancer. The retreat is hosted and directed by Indigo, a well-known Washington State belly dancer.

We encourage all dance styles and levels to attend. Emerald Sanctuary has and always will be an accepting and safe place to explore your dance.

The workshops are set up so you get a well-rounded experience from a variety of instructors. Past instructors have included Adriene Rice, Alimah, Amy Sigil, Aubre Hill, Aziza, Carrie Konyha, Dahlia Moon, Delilah, Elisa Gamal, Habib, Hasani, Leila Farid, Magidah, Maria Morca, Nadira, Silvia Salamanca, Tamalyn Dalal, Zephyr, our very own Indigo, and many others. Almost every year we have live music by House of Tarab and their guests for your hafla performance.

The retreat is a laid-back and relaxing experience amongst new and old friends. Between workshops there is plenty of free time to shop with our vendors, explore the rugged and beautiful landscape, cool off with a swim in one of several lakes, or take a nap on the lawn. We hope you join us this year and every year after.

We welcome you to join our Facebook group! Get to know us and socialize with us!


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Spruce Lumber

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Pella Windows !

windowWe are proud to announce that in addition to our regular lines of windows, we are able to offer our customers the Pella brand of windows!

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The big news as far as our products are concerned, was

The  commitment this year to sell the new brown

coloured Pressure Treated Lumber. Sales in this

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are numbered.

Our spruce lumber comes exclusively from Canada's forests.

The term "stud" gets mixed up sometimes. A stud can be 8' long or "precut" to 92-5/8" or 104-5/8".

Long lengths of spruce (for example 2"x12"x24') may not be spruce at all! They could be  a species of white fir or Hemlock/Fir.

Spruce Lumber

Spruce lumber is the choice for general framing. It is not recommended for decks or other exposed areas. We buy in kiln-dried spruce lumber and almost always, we will have a premium grade in stock.

Our designers have tables that provide us with the information about the appropriate size to use in applications like floor joists or ceiling rafters.

We carry a complete range of sizes and the product is stored under a roof once the tarp has been taken off.

lumberAlthough we are in the building business, not manufacturing, we do carry a small assortment of Maple and Oak lumber in both 1" and 6/4" sizes. The grade is FAS (clear). The widths may be random.Come in and check out our selection!


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Black Water Review

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A terrifying tale of survival in the mangrove swamps of Northern Australia

Take Wolf Creek, relocate to Croc Swamp and you’ve nailed this intense lo-fi horror from Down Under. Based on real events, the movie presents a predicament rather than a narrative - three tourists get their boat overturned by a crocodile, escape up a mangrove tree and realise they’re stranded with a hungry predator staking them out below.

Shot on location with real crocs, the end result is as much a hostile survivalist eco-nightmare as a traditional creature feature. Raw turns and skilfull shot-craft sustain a sense of menace - less so a third-act plunge into Ripley-esque silliness.

A B-movie in mock-doc “true story” disguise then, but one that bites deep.

A barely disguised B-movie - but one that bites deep.

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Autistic Children with Epilepsy: Higher Risk of Unexplained Death

By HERWriter
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higher unexplained death  risk for autistic children with epilepsy PS Productions/PhotoSpin

Unexplained Deaths Attributed to Autism, and Autism with Epilepsy

Tyler, a 17-year-old autistic boy, was found dead by his mother after possibly having suffered a seizure in his sleep. When the autopsy report came back, it said "no apparent cause for death." An article about this sad situation was published by The Simons Foundation Autism Research Initiative.

This is what’s known as a sudden unexpected or unexplained death in autism or, where the case involves a known diagnosis of epilepsy as well as autism, sudden unexpected/unexplained death in epilepsy (SUDEP).

Disturbingly, unexplained deaths in people with autism are not uncommon. In fact, deaths in autism-only people are 2.4 times higher compared with the general population. (4)

A study conducted by Autism Speaks also showed that in 2006, 2007 and 2009, 50 percent of recorded deaths in California in otherwise healthy individuals with autism were attributed to unknown causes. (4)

SUDEP “is believed to be responsible for the deaths of more than 4,000 people in the U.S. each year, most of them younger than 22 years. Sudden death is at least 20 times more common in people who have epilepsy compared with the general population ...” (4)

Living with Autism and Epilepsy

The Centers for Disease Control and Prevention estimates that autism spectrum disorders affect about 1 in 110 children in the United States (or about 8.25 percent of children), and epilepsy impacts nearly 3 million Americans. (3)

Autism Speaks reports that as many as “one in 20 children diagnosed with autism by age 3 could either already have epilepsy or develop epilepsy later in life.”

People who have both autism and epilepsy, which is up to 39 percent of people with autism, have more treatment-resistant seizures and a much higher death rate than people living with just one of the conditions. (1,2,3)

Interestingly, more than 50 percent of people with autism who don’t experience clinical seizures demonstrate unusual, epileptic-like, brain wave patterns. (4) Researchers do not know, yet, whether these unusual brain wave patterns bring with them an increased risk of sudden death.

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how do i get rid of contact dermatitis

By December 5, 2009 - 9:09pm
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Two weeks ago,

I started iching like crazy under my arms and on my outside my private parts. I can not figure out what the problem is all of a sudden. The dermatologist thinks it is contact dermatitis. He prescribed clotrimazole and betamethasone dipropionare cream usp 1%/0.05% base. Two days and no relief! I stopped the perfumes, soaps and deodorants and no fix. I even put new clothes and underwear on today to eliminate chance of laundry detergent and fabric softeners. What should I do? I am up all night scratching and all day. I am so uncomfortable.

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EmpowHER Guest

I had the same thing for 2.5 years, primarily in the vaginal area and I was miserable. In short, what CURED me was taking hydroxizine pills for the itch but the magic bullet was using Marcal brand toilet paper because it is unscented and most importantly unbleached toilet paper. I also tried Seventh Generation toilet paper -but for some reason Marcal did the trick. It took approximately 4 weeks, but I don't have any issues any more and it's going on 2 months now. I am trying to locate every blog so I can share this. Please respond and let me know if this helped you. Remember it took at least 4 weeks - so be patient.

August 19, 2014 - 11:56am
EmpowHER Guest
Anonymous (reply to Anonymous)

I've been dealing with similar symptoms for going on 5 weeks now. Burning/irritation of the labia minora. Did 2 rounds (2 weeks)of yeast medication and a 1 time 4 pill dose of medication for bacterial infection after which all tests came back negative. I have yet another doctor appointment in 2 days. No idea what they will tell me since all tests have been negative. Dr. Said it looked like irritation as oppose to infection 2 weeks ago at last appointment, but this was before last round of testing. I have found that after 5 or so days symptoms would begin to clear then reappear. About 4 days ago I had a bad flare up not only on the labia minora but around the anus as well. At this point I'm thinking it has something to do with the toilet paper I was using (Scott extra soft) because I've recently read that extra soft tissue tends to leave more lint behind..... Or from use of flushable wipes. I was prescribed nystatin and triamcinolone cream at my last appt. apply 2 times a day. After the flare-up I applied to all affected areas at night and most of the anal irritation was gone by the morning. The labia irritation is still there but I'm wondering if its due to more sensitive skin and the issue persisting longer there already. From the beginning I have felt the irritation more AFTER using the bathroom not WHILE going in the case of most infections. I'm glad to hear of the toilet paper recommendation because the last 4 days I've been using baby wash cloths washed in free & clear detergent and I know this can't be a long term solution. We cloth diaper our youngest so cloth toilet paper wasn't much of a stretch. Sorry for the book. Glad to share experience. It's daunting and stressful but ladies do your research and continue seeing your doctor until you get answers. A lot is trial and error as we are all different. I have been using the same toilet paper and wipes for over a year.....apparently irritation doesn't usually show up when it first takes place which I believe is why it doesn't heal overnight or as soon as the irritant is removed. Crossing my fingers it was the wipes and to but I will try to update. I've seen on other sites besides this one that once the irritant is identified it can take 2-4 weeks to clear up. Hopefully this will help someone.

September 7, 2015 - 10:19pm
EmpowHER Guest

Did it ever go away I have the saaame problem

May 24, 2012 - 10:47pm

Second doctor gave me antihistimines. With them the itching stops but without them I itch so much! I have eliminated so much of what I thought could have been causing the itching and I am still itching witout the meds.

December 24, 2009 - 9:29am

I think you need to get a second opinion about what may be going on. If your medication is not working then you have clearly been misdiagnosed.

Keep us posted on how things work out and good luck!

December 6, 2009 - 9:36pm

Can you call your Gynecologist for an appointment? I am concerned about the rash and itchiness on the skin around your vagina and inner thighs, and this should be medically evaluated by a doctor.

Have you had any sexual contact prior to the itching? There are many sexually-transmitted infections (they clear up with proper medication---don't worry!) that cause itchiness around the genital area.

(It sounds like your dermatologist only looked at the area underneath your arm, correct?) Did your dermatologist tell you how long it will take to feel relief (it's "only" been two days on your medication), and if s/he said immediately or within a day, you should call your dermatologist Monday AM and update him/her on your (lack of) progress.

December 6, 2009 - 2:15pm

It feels like all of my sweat in those areas is not being able to come out.

December 6, 2009 - 12:22pm

I wonder what I need to do next. Living like this is not an option!

December 5, 2009 - 10:39pm

the itching started about one month after taking the antibiotics. I now have a red rash and bumps from so many days of repeated iching in that area.

no real discharge and hardly any internal itching. I am allergic to aluminum cholride found in regual deos, so that is why i use only the same natural deo for the last 10 years and have stopped for the last week. Also, allergic to sublock when used on my face. Nothing has changed in the last several weeks and no new products in my house either.

December 5, 2009 - 10:37pm

Hmmm... sounds interesting.

I have a few other questions

So just to be clear, there is no actual rash, just itching?
When did it start in relation to taking the anitbiotics?
Have you ever had anything like this before?
Do you have allergies to anything that you know of?
Have you had any vaginal itching or change in vaginal discharge?
Did anything change around the time of the onset?

December 5, 2009 - 10:31pm
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Allergic Contact Dermatitis

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