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Interview with Tony Zurovec on GOG.com
09-21-2011, 03:48 PM,
Interview with Tony Zurovec on GOG.com
GOG.com has posted their interview with Crusader series creator Tony Zurovec. There is a ton of fascinating tidbits which I've not yet heard from Tony. I'm planning to further analyze what is said in this interview. Nevertheless, here are some snippets:

Regarding "Crusader II"
Quote:The primary reason why Crusader II was never completed was because I was personally promised by a senior Origin executive ? before official development on the first game ever started ? that I would receive royalties based upon the game?s profitability. After a year and a half of extremely hard work, the game sold far better than expected and, for many months after its release, I was repeatedly assured by Origin?s top management that the royalties would be forthcoming. As I neared completion of the next title in the series, I began to grow impatient with the stalling and pushed for a resolution. It eventually fell to one of EA?s top executives to inform me that Origin management didn?t have the authority to make such promises and that EA wouldn?t honor it. Instead, the EA executive said, all that they could offer me was a new block of options that would vest over a four-year period. I said that rather than accept that offer ? which was dramatically inferior - that I?d be leaving the company after I finished No Regret. Leaving Origin was one of the hardest things that I?ve ever done ? it had felt like a home ? but there was no way that I was going to support such a betrayal with more of my life.

Regarding No Remorse development
Quote:An interesting point about No Remorse?s development is that a debt of gratitude is owed to someone ? I never knew who - in the European marketing department of parent company Electronic Arts (EA). The initial sales estimates for the game had been relatively low because the marketers couldn?t point to any similar titles ? there weren?t any - and gauge Crusader?s commercial potential. As the game neared the end of its original development timeline, I tried to get those estimates raised in order to justify an additional three months of development time that was desperately needed in order to polish and debug the game. Origin and EA North America?s marketing departments refused to budge, but when some visiting European marketing executives saw the game at that late stage they dramatically increased their sales estimates and that was it ? the extension was approved. When the game was released, even those revised estimates were easily exceeded. I have always thought that Crusader would not have done nearly as well as it did had it not gotten those three additional months.

Check out the whole interview.
"First let me say welcome to the Resistance, Captain."
09-21-2011, 05:16 PM,
Re: Interview with Tony Zurovec on GOG.com
Just finished reading the whole interview. Interesting stuff.
09-21-2011, 10:00 PM,
Re: Interview with Tony Zurovec on GOG.com
I see that one of my questions made it in somehow after all.

"And couple questions from our users that repeated many times:
Why is Silencer's armor red?"

" ... On the fictional side, the Silencer?s armor was red because the government?s hold on power depended upon ? at any given time - most of its people submitting?conforming?to the system. A government?s power is ultimately derived from its people, and a widely despised government can only maintain the status quo if it can keep the number of people simultaneously resisting its control to a minimum. Such governments typically employ a wide array of mechanisms to accomplish that objective, and one of them is fear and intimidation. Silencers were intended to be visible signs of the government?s military power ? a clear reminder of what would befall anyone who sought to overturn the system. Their red armor made them stand out in a dreary Orwellian future?and that was the point."

I had always wondered about that and submitted that as one of my questions. I never found the red suit to be stealthy while Silencers where meant to be one-man armies capable of everything and I figured stealth would be part of that. But the intimidation point on the fictional side actually makes sense. A Silencer doesn't need stealth. It's much scarier knowing a Silencer is out there ready to kick your ass. The technical reasons make a lot of sense also of course and I like the Spartan reference.
I guess what they say is true. Send a Silencer in and the job gets done.
10-03-2011, 01:29 AM,
Re: Interview with Tony Zurovec on GOG.com
If he had gotten a good lawyer he probably could have made EA honor the promises made by Origin. "Apparent authority" is a subject that most lawyers learn before finishing law school.

Just think, a business lawyer could have saved Crusader II...

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4th International Conference on Green Chemistry and Sustainable Engineering

Madrid Spain

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The 4th International Conference on Green Chemistry and Sustainable Engineering is organised by academics and researchers belonging to different scientific areas of the University Complutense of Madrid, University Carlos III of Madrid, University of Extremadura and University of Las Palmas de Gran Canaria with the technical support of Sciknowledge European Conferences.

The event has the objective of creating an international forum for academics, researchers and scientists from worldwide to discuss worldwide results and proposals regarding the soundest issues related to green chemistry and sustainable engineering.

This event will include the participation of renowned keynote speakers, oral presentations, posters sessions and technical conferences related to the topics dealt with in the scientific program as well as an attractive social and cultural program.

The papers will be published in the Abstracts E-book of the Conference. Those communications considered of having enough quality can be further considered for publication in International Conference Journals. At the authors’ discretion, those works not suitable for publication in any of the congress journals will be published in the Extended Proceedings E-book of the International Congress on Green Chemistry and Sustainable Engineering.

The Conference will also have a space for companies and/or institutions to present their products, services, innovations and research results. If you or your company is interested in participating of this exhibition, please contact the Technical Secretariat.

Asia Pacific’s Hub For Collaboration On Sustainable Development
An Eco-Business initiative
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pure products. clean future.

Montreal Bans Plastic Bags

Montreal implemented its long-planned ban on plastic bags on January 1, 2018, making it the first major Canadian city to do so.

The ban covers the distribution of lightweight plastic bags with a thickness of less than 50 microns as well as biodegradable bags, which contain an additive that causes them to decompose in heat and light.

City officials say lost or abandoned plastic bags are a visual nuisance that cause considerable harm to terrestrial and marine ecosystems and often end up in landfills.

“We use roughly 2 billion of these bags annually and only 14 per cent are reintegrated in recycling plants,” said Jean-François Parenteau, the city council member responsible for the environment.

City officials say the ban is intended to encourage people to move away from single-use products and to adopt reuseable bags.

Victoria has also announced its intention to ban plastic bags beginning in July 2018, while Vancouver is mulling the issue.

For the full article, visit: https://globalnews.ca/news/3940536/no-more-plastic-bags-in-montreal-first-major-canadian-city-to-implement-ban/

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The Bible and Homosexual Practice Paperback

Texts and Hermeneutics

by Robert Gagnon;

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The Bible and Homosexual Practice

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Gagnon offers the most thorough analysis to date of the biblical texts relating to homosexuality. He demonstrates why attempts to classify the Bibles rejection of same-sex intercourse as irrelevant for our contemporary context fail to do justice to the biblical texts and to current scientific data. Gagnons book powerfully challenges attempts to identify love and inclusivity with affirmation of homosexual practice. . . . the most sophisticated and convincing examination of the biblical data for our time.Jürgen Becker, Professor of New Testament, Christian-Albrechts University

The Bible and Homosexual Practice by Robert Gagnon was published by Abingdon Press in February 2003 and is our 19903rd best seller. The ISBN for The Bible and Homosexual Practice is 9780687022793.

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Emily Dodd

FEATURE – Emily Dodd, author of Banana me beautiful

Edinburgh’s Emily Dodd publishes her first e-book Banana me beautiful is a book with a difference. It’s a journey of poetry, art and photography by a child, teenager and adult – Emily Dodd. Award winning author Emily currently lives and works in Edinburgh where tells stories, delivers Environmental Education, makes podcasts and films and writes for BBC […]


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Elektra, Royal Opera House (Review)

Christine Goerke as Elektra in Elektra © ROH / Clive Barda 2013 by Royal Opera House Covent GardenApplause for the conductor – even if it is Andris Nelsons – is just about the last thing we need to hear when Richard Strauss is about to fling down the brutal chords which spell out the name of Agamemnon. Surely the start of Elektra is now one of those occasions where we must set … [Read More]

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Prom 55: Britten “Peter Grimes”, English National Opera, Edward Gardner – Review ****

You can take the opera out of the opera house but you can’t take the opera house out of the opera – not when the spirit of David Alden’s benchmark 2009 production of Britten’s Peter Grimes resides so potently in English National Opera’s collective psyche. Company members may have come and gone in the interim … [Read More]

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Lehar “The Merry Widow”, Philharmonia Orchestra, Wilson, Royal Festival Hall (Review)

Lehar’s Merry Widow has been been spreading enchantment across the globe for well over a century. She’s the vintage champagne of operettas and the prospect of John Wilson popping her cork was more than a little enticing. Wilson, one feels, instinctively knows how this music goes and indeed did so before even the composer put … [Read More]

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EFI Mezzera Jigger

EFI Mezzera JIGGER – Technologies for open width fabric

With over 60 years experience and thousands of machines sold throughout the world, Mezzera is in the ideal position to supply a range of jiggers for all needs, from the smallest jigger for sampling to the jumbo machine including all intermediate sizes. The Mezzera jiggers are the outcome of the long experience acquired working on the field.


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 Global Travel Media » Blog Archive » Taste the power of all Asia Pacific W Hotels and feast your eyes on a magnificent buffet-style selection of afternoon delights at weekends in WOOBAR

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Taste the power of all Asia Pacific W Hotels and feast your eyes on a magnificent buffet-style selection of afternoon delights at weekends in WOOBAR

November 5, 2013 Lifestyle No Comments Email Email

The soft touch, the sensual taste, the sweet smell… Capture the thrill at WOOBAR, where your 5 senses will be tempted and teased to climax with an array of irresistible tastes inspired by Asia Pacific W Hotels’ Afternoon Tea Sets in its “TEA-SE ME” Afternoon Tea Buffet.

Starting from November, succumb to your desires and indulge in over 30 types of desserts in this brand new Afternoon Tea Buffet! Imagine walking into a forbidden garden where all the devilishly delicious sweets await in different shapes and bright colors.

Sharing the same essence of all Asia Pacific W Hotels’ Afternoon Tea Sets, “TEA-SE ME” will feature 9 types of offerings that are specially curated by the hotels. From classic sandwiches, local specialties, eye-catching fun eateries and healthy dishes to chocolate delights, cream-based sweets, baked goodies, W signature savories and even food cocktail bites, all your wildest food fantasies will become reality.

The “Fresh duck, lavender with purple potato crumble” is as unconventional as it is tasty. Crushing the purple potato into powder form and having it dried overnight, its rich taste becomes more pronounced and concentrated. By mixing it with fresh duck breast, the meat flavor becomes more heavenly as both complement each other well. With pinches of lavender sprayed upon, a wonderful sensation is produced.

For those who yearn for something even more unique, the “Green Yuzu Martini Lollipop” shall do the trick. Its sour and very fragrant Japanese citrus Yuzu within serves as an appetizing contrast to its dreamy green creamy vanilla caramel coating, which are all crafted into lollipops. Just one bite of it, the Yuzu martini will burst inside your mouth, leaving a tingling and refreshing taste. Other highlights include       “T – ramisu in the flowerpot”, “Compressed melon, daiquiri melon and angus beef”, “Pistachio cake and cherry confit with lemon gel”, “Beijing duck bun, leek, hoi sin sauce” and many more.

It is after all an afternoon TEA buffet, how can there be no tea? So we have called in the world-renowned tea brand – Dilmah t Series – to wet your lips with 3 types of premium tea. Supreme Ceylon Single Origin, one of the finest teas in the world, is recognized for its bright, brisk and full-bodied flavor specially created in Ceylon, an island known for its wide variety of tea leaves. Cinnamon Smoked Kataboola Estare Pekoe on the other hand has a mellow yet sweet taste with amber liquor that is gently smoked for three days to achieve a refined outcome. The last tea, Longjing Tea with Rose and Lotus, gives off a unique fragrance, reminiscent of hay and fresh herbs with a gentle character and lingering, sweet aftertaste. The buffet including the Dilmah t Series teas is available at HK$248+10% per person during weekends.

After sight, taste and smell, it’s time to satisfy your senses of touch and sound. We have got fruit potions and syringes for you to spray upon your treats, allowing you to create your own flavors. Together with soothing W Music played through the afternoon, get ready to be teased pleasurably.

Can’t resist this tempting treat? Reach out to WOOBAR at woobar.hk@whotels.com or 3717 2889.

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 Global Travel Media » Blog Archive » The Yukon Quest International Sled Dog Race Travels 1,000 Miles to Fairbanks, Alaska

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The Yukon Quest International Sled Dog Race Travels 1,000 Miles to Fairbanks, Alaska

February 9, 2017 Destination North America No Comments Email Email

The 34th Yukon Quest International Sled Dog Race began February 4, 2017 in Whitehorse, Yukon Territory, Canada and will finish on the frozen Chena River in downtown Fairbanks, Alaska. Dog mushing is the Official Alaska State Sport, with the Yukon Quest and the Iditarod being Alaska’s premiere mushing events. The Yukon Quest Trail follows historical gold rush and mail delivery dog sled routes. Once the transportation “highways” of the northern frontier, the Yukon Quest Trail now comes alive each February with the frosty breath and haunting howls of dog teams consisting of one human musher and 14 canine athletes.

The 2017 Yukon Quest International Sled Dog Race to Fairbanks, Alaska is underway. Photo by Julien Schroder, courtesy of Yukon Quest International.

Race participants follow a 1,000-mile trail that traverses some of the most sparsely populated and most remote and pristine country on the North American continent. Temperatures can vary dramatically from -80F to 30F. High winds and whiteout conditions, rough gravel, hard packed snow, frigid open water, mountainous terrain and river flats can speed up the race or slow it to a crawl. Mushers driving sleds loaded with 250-300 pounds of gear are challenged by changes in elevations as they climb windy and drifted mountain summits, and the sheer distances between checkpoints, some over 100 miles.

Twenty-one mushers took off from the start line in Whitehorse. This year’s participants include three past champions, all Alaskan residents. Allen Moore won back-to-back titles in 2013 and 2014; Hugh Neff took the crown in 2012 and 2016; and Brent Sass, who won it all in 2015. The 2017 Yukon Quest should take 10 to 14 days to run 1,000 miles through nine communities en route to Fairbanks. For the latest news and information, visit yukonquest.com.

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What is the Egyptian Game SENET?

What is Senet?

Senet was a board game played by ancient Egyptians. It contained thirty squares, and players tossed a sheep's knucklebone to determine their moves. Senet was played by rich and poor alike.

Egyptian board game senet
Senet board game inscribed with the name Amenhotep III
possibly from his tomb.
Games are popular today, but what about back in Ancient Egypt?

People sometimes assume humans were super serious in the past. I'm not sure why this is the case. There's nothing to suggest this is true. In fact, Ancient Egyptians loved parties, dancing, music, and games.

What was Ancient Egypt's most popular board game?

More facts about Senet:

Senet was a popular way to pass the time. People kept boards in their homes. Even Egypt's pharaohs were known to play. Rich people had fancy boards made of materials such as jade and ivory.

Regular Egyptians played Senet, too. Boards could be made of wood or drawn on a sheet of papyrus that could be rolled up and put away.

Here's a fun fact: makeshift Senet boards were actually carved right into the stone pavement! That way, people could challenge one another to a game outside.

Other players might draw Senet boards in the sand along the banks of the Nile the way you draw a hopscotch board with chalk. Some might have drawn Senet boards in the dirt outside their homes.

  1. Senet boards contain 30 squares laid out in rows of 10. Each player has 5 pieces.
  2. Players throw sticks or sheep's knucklebones to determine how many spaces to move. Wealthy Egyptians used a piece of carved ivory or other precious material shaped to look like a sheep's knucklebone.
  3. One side of each throwing stick is painted black. The number of black sides you roll determines the number of spaces you can move.
  4. Players move their pieces down ten squares, turn the corner, complete the thirty squares and remove the piece from the board.
  5. Players keep moving their pieces in this manner until all pieces have been removed from the board.
Ancient Egyptian Board Game called Senet
Ancient Egyptian Board Game called Senet
Available on Amazon: Click to see in store

Originally, Senet was played for fun to pass the time. But as the game became more popular, it took on a more serious tone. Ancient Egyptians believed that winning a game in the Afterlife could help them when they were dead!

Therefore, the board game was included in tombs so that the deceased could play for all eternity.

Maybe that's why Senet became so popular with the living. Everyone was practicing their Senet skills before it was too late!

Blue Senet Game Board photo above: Keith Schengili-Roberts

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This is just a sample of some of the great work we've done for clients - if you'd like to know more please get in touch:

Kids v Evo Xplorer

What happens when you combine a group of toddlers with a brand new iPhone6 encased in tech21's Evo Xplorer? A whole lot of fun - check it out here.  Just one of many experiential, influencer and editorial based activations we devised for our Australian tech21 #lifehappens PR outreach program, which very successfully launched the product to market.

Suite Success

Meet Stanley - NetSuite's annual Suiteworld User Conference mascot - highly sought after for selfies.  He was just one of the many stops in our tightly crafted media and influencer campaign which saw us secure a top rate schedule of interviews for our Australian and New Zealand contingent. The results?  We cut through the online chatter and secured more than 80 tier one Australian media clips in just two weeks and built a solid foundation for ongoing engagement.

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Icing on the cake

Our ongoing campaign to support online advertising's "Big Tent" approach in the Australian market has resulted in IAB Australia dominating the ad tech market space, securing media SOV consistently triple that of other industry associations in the sector.  We don't rest on our laurels or assume anything though so when we can find an opportunity to mix it up a bit we do - like the stunning cakes sharing the latest milestone, which were very well received by all the major newsrooms and trade desks.

Connecting with customers

With the challenge of keeping the fast moving advertising market focused on AOL in Australia and across SEA, Einsteinz developed a full communications program spanning media relations, customer events, trade show activation, marketing outreach, speaker programs and major research projects such as the State of the Video Industry research.  The program which sees our team embedded in the AOL international team, has resulted in enviable customer engagement and activation results.

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What to Ask When Shopping for Dental Insurance Quotes

Are you afraid of the dentist? About 30% of the population are. But taking good care of your teeth and gums is an important part of your overall health. Poor oral hygiene can lead to bone loss and even heart disease. If it’s been a while since your last visit, you’ll be happy to learn that there are new procedures that make dental care less physically painful. Get good dental insurance coverage and you can lessen the financial pain, too. Here are some things to consider and some questions to ask when looking for dental insurance quotes.

  • Do you already have a dentist you like? Make sure he or she accepts the dental insurance plans you’re looking at. Just as some health insurance restricts your use of doctors, there are dental insurance plans that specify which dentists you can see. If you really like your dentist, it might be worth paying a slightly higher premium to retain that choice.
  • One of the most important questions is what treatments your dental insurance plan covers. Look for dental insurance quotes for plans that provide 100% coverage for minimum prophylactic care such as at least two cleanings a year and xrays.
  • When getting dental insurance quotes, ask whether the plan restricts payment to the cheapest treatment or whether it allows you and your dentist to decide on the best treatment plan. If there are treatment restrictions, ask if you have the option of choosing the more expensive treatment and paying the difference.
  • Find out if and under what conditions your dental insurance requires preauthorization for treatment.
  • Compare the deductibles, co-payments and other out-of-pocket expenses for other routine dental procedures, as well as the maximum allowed plan benefit. Most dental insurance plans are on the calendar year and any unused benefits do not role over into the next year. Conversely, if you use up your maximum benefits in July, you’ll have to pay for any required services through December.
  • Understand what the various dental plans you’re looking at consider “usual, customary and reasonable.” UCR in dental insurance lingo means the insurer sets the price for what it will pay for every covered dental procedure. It is rarely based on what your dentist actually charges. In-plan (preferred) dentists agree to charge you the UCR.
  • Unlike other health care insurance, there is seldom a waiting period to cover pre-existing dental conditions, but if you’re concerned, this is certainly a question to ask when you’re getting competitive dental insurance quotes.

Finally, if you’re among that 30% of folks who are terrified of dentists, ask if the dental insurance coverage extends to sedation. Some of the questions to ask specific to sedation are:

  • Whether the plan covers oral, IV or laughing gas sedation
  • Whether there are limits on the use of sedation based on the amount of work required and the procedure done
  • Whether there are limits on the frequency or duration of sedation

Most dental insurance plans do not pay for sedation except under specific conditions depending on plan. However, many dentists now offer sedation as a free service to entice the dental-phobic to get the treatments they need.

©2017 eInsurance. All rights reserved by E-Insure® Services, Inc.


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Four day-long workshop and music festival

The first Ekodrom festival was held in 2012. It was organized by Ekodrom Association with the help of volunteers who shared our enthusiasm and welcomed the idea. The Festival is designed as a four day-long  companionship in nature - through sharing knowledge and skills, enjoying music and dance, creating a society of active people for better now, on local and global scale, protecting the environment and natural resources. Through the synergy of rural and urban aspects of life, Ekodrom festival promotes important but neglected values as well as culture based on togetherness, tolerance and appreciating differences.

In the last five years, many musicians and DJs have performed on the Festival!

Cinkuši  / Jeboton / Veja / Balade Petrice Kerempuha / Kaira Kela / Zykopops / Mladen Pašut / Šumovi protiv valova / Kobok / Drvored / Djmawi Africa / Antenat / Repassage

Dbart / Bocca Sofistifunk / Osobna / Đon Kesten / Iva Kvakić / Sretni Edi / Oleg Moskaljov / D Gree /  Nenad Kovačić / Yves / Sisters in Roots / Mile / Miron Milić / Sergio / Ilko Čulić /

workshops and lectures:

Carpentry / organic gardening / photography / bee-keeping / blacksmithing / didgeridoo /  yoga / weaving / singing / juggling / camera obscura / hula hoop / making instruments / local currencies / protection of water and rivers / Chinese medicine / wild plants and mushrooms / good economy / etc.

Our musical program includes well known artists but at the same time offers opportunities to young performers whose time is about to come. Workshops are an important segment of the Festival, which is constantly developing and improving, year by year.

This year, some workshops will start in spring and will be held on several occasions, so the results can be presented to wider audience during the Festival. Information about the workshops will soon be available on Ekodrom´s FB page „Ekodrom festival“.

The objective of the Festival is sustainability which excludes sponsoring or branding activities. In that way, we try to keep our independence and motivate our guests to active participation.

Healthy food and free camping are also important aspects of the Festival. We are very thankful  to all volunteers that have been helping us  with the camping site and the kitchen for the last five years.

It is with great pleasure that we announce the culinary cooperation with the Taste of Home crew, who is going to make your palate happy at Ekodrom Festival!

Taste of Home is a social cooperative for intercultural cooperation that employs refugees and migrants in Croatia. The goal of this organization is to integrate and get to know the culture and customs of persons who are trying to build a home here. A year ago the cooperative launched a food catering business, preparing specialties from its members' countries. It also organizes language courses, culinary workshops, themed evenings and many other interesting activities which enrich our society and improve the life of people trying to find a new home and a place in the sun.

Enjoy your meals at Ekodrom Festival!

15. - 18. 6.2017.

Croatia & Ex Yu countries

Festival ticket – 4 days - 210 kn (28 EUR)

Daily ticket:

Thursday, 15.06. - 40 kn (5 EUR)

Friday, 16.06. – 70 kn (9 EUR)

Saturday, 17.06. – 70 kn (9 EUR)

Sunday, 18.06. – 50 kn (7 EUR)

Workshops: carpentery, forest garden, TRE – 40 kn (5 EUR), traditional singing – 100 kn (13 EUR)

Additional workshops, program for kids and camping spot – free!

Other countries

Festival ticket – 4 days - 420 kn (56 EUR)

Daily ticket:

Thursday, 15.06. - 80 kn (10 EUR)

Friday, 16.06. – 140 kn (18 EUR)

Saturday, 17.06. – 140 kn (18 EUR)

Sunday, 18.06. – 100 kn (14 EUR)

Workshops: carpentery, forest garden, TRE – 80 kn (10 EUR), traditional singing – 200 kn (26 EUR)

Additional workshops, program for kids and camping spot – free!

Early Bird festival tickets available until 30.04.2017.

© EKODROM 2017. All Rights Reserved


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Wall Street punishes Cree for results

Despite the fact that Cree Inc. (CREE), Durham, N.C., set a new sales record for the quarter its stock price took a 10% dive, as Wall Street prognosticators were disappointed with Cree's financials. There's lots of discussion out there right now on the future of Cree and other LED stocks.

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Systemic Lupus Erythematosus: Genetic and Epigenetic View

Systemic lupus erythematosus (SLE) is a common systemic autoimmune disease with complex aetiology, in which susceptibility is determined by the combination of genetic, environmental, epigenetic and stochastic factors. SLE is very heterogeneous in its clinical manifestations and the presence of different autoantibodies may predict different set of clinical outcome. However, despite considerable accumulated knowledge, the detailed pathogenesis of SLE still remains unknown. Several studies have indicated the importance of deoxyribonucleic acid (DNA) hypomethylation in the aetiology of SLE. Recent advances in high‐throughput genotyping technologies and high‐density genetic association studies have identified and replicated many SLE susceptibility genes in different populations. In this article, we outline our current understanding of some genetic and epigenetic aspects of SLE.

Keywords: SLE; Candidate gene; Linkage; Association; Epigenetic; DNA methylation

Figure 1.

Malar rash in a lupus patient. The erythematous eruptions involve the dorsum of the nose and the malar areas, and spare the nasolabial folds. Reproduced with permission from Sawalha AH, Diaz L and Harley JB (2006) Systemic lupus erythematosus. In: Diaz L (Ed.) Principles of Molecular Medicine, 2nd edn, pp. 970–978. Totowa: Humana Press Inc.

Figure 2.

Inhibiting DNA methylation induces T‐cell autoreactivity in vitro and autoimmunity in vivo. T cells treated with the DNA methylation inhibitor 5‐azacytidine overexpress methylation sensitive genes such as CD11a and CD70. These T cells become autoreactive and capable of stimulating autologous B cells in vitro, an effect that can be inhibited by anti‐CD70 antibodies. Upon adoptive transfer into mice, 5‐azacytidine treated T cells induce a lupus‐like autoimmune phenotype characterized by the production of autoantibodies and the development of glomerulonephritis, alveolitis and central nervous system (CNS) lupus lesions.

Figure 3.

Abnormal T‐cell DNA methylation in the pathogenesis of lupus. ERK pathway signalling is defective in lupus T cells. DNA methyltransferase 1 enzyme (DNMT1) is regulated in part by signalling through the ERK pathway, and therefore the expression of DNMT1 is reduced in lupus T cells. This results in T‐cell DNA hypomethylation and overexpression of methylation senstive genes such as CD11a, CD70 and Perforin, making T cells autoreactive and capable of inducing autoimmunity.

Aitman TJ, Dong R, Vyse TJ et al. (2006) Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans. Nature 439(7078): 851–855.

Alarcón‐Riquelme ME (2003) A RUNX trio with a taste for autoimmunity. Nature Genetics 35(4): 299–300.

Atagunduz P, Appel H, Kuon W et al. (2005) HLA‐B27‐restricted CD8+ T cell response to cartilage‐derived self peptides in ankylosing spondylitis. Arthritis and Rheumatism 52: 892–901.

Ballestar E, Esteller M and Richardson BC (2006) The epigenetic face of systemic lupus erythematosus. Journal of Immunology 176(12): 7143–7147.

Busslinger M and Flavell RA (1983) DNA methylation and the regulation of globin gene expression. Progress in Clinical and Biological Research 134: 193–203.

Cornacchia E, Golbus J, Maybaum J et al. (1988) Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity. Journal of Immunology 140(7): 2197–2200.

Deng C, Kaplan MJ, Yang J et al. (2001) Decreased Ras‐mitogen‐activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients. Arthritis and Rheumatism 44(2): 397–407.

Deng C, Lu Q, Zhang Z et al. (2003) Hydralazine may induce autoimmunity by inhibiting extracellular signal‐regulated kinase pathway signaling. Arthritis and Rheumatism 48(3): 746–756.

Fanciulli M, Norsworthy PJ, Petretto E et al. (2007) FCGR3B copy number variation is associated with susceptibility to systemic, but not organ‐specific, autoimmunity. Nature Genetics 39(6): 721–723.

Graham DS, Manku H, Wagner S et al. (2007) Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation. Human Molecular Genetics 16: 579–591.

Graham RR, Ortmann WA, Langefeld CD et al. (2002) Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus. American Journal of Human Genetics 71(3): 543–553.

Gregersen PK, Lee HS, Batliwalla F and Begovich AB (2006) PTPN22: setting thresholds for autoimmunity. Seminars in Immunology 18: 214–223.

Hauptmann G, Tappeiner G and Schifferli JA (1988) Inherited deficiency of the fourth component of human complement. Immunodeficiency Reviews 1: 3–22.

Helms C, Cao L, Krueger JG et al. (2003) A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis. Nature Genetics 35(4): 349–356.

Hiromine Y, Ikegami H, Fujisawa T et al. (2007) Metabolism. Trinucleotide repeats of programmed cell death‐1 gene are associated with susceptibility to type 1 diabetes mellitus. Metabolism 56(7): 905–909.

Lee JY, Goldman D, Piliero LM, Petri M and Sullivan KE (2001) Interferon‐gamma polymorphisms in systemic lupus erythematosus. Genes and Immunity 2: 254–257.

Lee YH and Nath SK (2005) Systemic lupus erythematosus susceptibility loci defined by genome scan meta‐analysis. Human Genetics 118: 434–443.

Nakashima H, Inoue H, Akahoshi M et al. (1999) The combination of polymorphisms within interferon‐gamma receptor 1 and receptor 2 associated with the risk of systemic lupus erythematosus. FEBS Letters 453: 187–190.

Nath SK, Kilpatrick J and Harley JB (2004) Genetics of human systemic lupus erythematosus: the emerging picture. Current Opinion in Immunology 16(6): 794–800.

Nielsen C, Hansen D, Husby S, Jacobsen BB and Lillevang ST (2003) Association of a putative regulatory polymorphism in the PD‐1 gene with susceptibility to type 1 diabetes. Tissue Antigens 62: 492–497.

Oelke K, Lu Q, Richardson D et al. (2004) Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors. Arthritis and Rheumatism 50(6): 1850–1860.

Pascual V, Farkas L and Banchereau J (2006) Systemic lupus erythematosus: all roads lead to type I interferons. Current Opinion in Immunology 18: 676–682.

Prokunina L, Castillejo‐López C, Oberg F et al. (2002) A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nature Genetics 32(4): 666–669.

Prokunina L, Padyukov L, Bennet A et al. (2004) Association of the PD‐1.3A allele of the PDCD1 gene in patients with rheumatoid arthritis negative for rheumatoid factor and the shared epitope. Arthritis and Rheumatism 50: 1770–1773.

Remmers EF, Plenge RM, Lee AT et al. (2007) STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. New England Journal of Medicine 357: 977–986.

Richardson BC, Strahler JR, Pivirotto TS et al. (1992) Phenotypic and functional similarities between 5‐azacytidine‐treated T cells and a T cell subset in patients with active systemic lupus erythematosus. Arthritis and Rheumatism 35(6): 647–662.

Sawalha AH and Harley JB (2004) Antinuclear autoantibodies in systemic lupus erythematosus. Current Opinion in Rheumatology 16(5): 534–540.

Sawalha AH and Jeffries M (2007) Defective DNA methylation and CD70 overexpression in CD4+ T cells in MRL/lpr lupus‐prone mice. European Journal of Immunology 37(5): 1407–1413.

Sawalha AH and Richardson BC (2005) DNA methylation in the pathogenesis of systemic lupus erythematosus. Current Pharmacogenomics 3: 73–78.

Sestak AL, Nath SK, Sawalha AH et al. (2007) Current status of lupus genetics. Arthritis Research & Therapy 9(3): 210.

Sigurdsson S, Nordmark G, Goring HH et al. (2005) Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. American Journal of Human Genetics 76: 528–537.

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Yang Y, Chung EK, Wu YL et al. (2007) Gene copy‐number variation and associated polymorphisms of complement component C4 in human systemic lupus erythematosus (SLE): low copy number is a risk factor for and high copy number is a protective factor against SLE susceptibility in European Americans. American Journal of Human Genetics 80(6): 1037–1054.

Yang Y, Chung EK, Zhou B et al. (2004) The intricate role of complement componenet C4 in human systemic lupus erythematosus. Current Directions in Autoimmunity 7: 98–132.

Yao X, Li YM, Hu ZJ, Li WZ and Chen ZQ (2005) Polymorphisms within the interferon‐gamma receptor associated with systemic lupus erythematosus [in Chinese]. Zhonghua Yi Xue Yi Chuan Xue Az Zhi 22: 320–323.

Yung RL, Quddus J, Chrisp CE et al. (1995) Mechanism of drug‐induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo. Journal of Immunology 154(6): 3025–3035.

Further Reading

DeWan A, Klein RJ and Hoh J (2007) Linkage disequilibrium mapping for complex disease genes. Methods in Molecular Biology 376: 85–107.

Huber LC, Stanczyk J, Jüngel A and Gay S (2007) Epigenetics in inflammatory rheumatic diseases. Arthritis and Rheumatism. 56: 3523–3531.

Jacob CO, Reiff A, Armstrong DL et al. (2007) Identification of novel susceptibility genes in childhood‐onset systemic lupus erythematosus using a uniquely designed candidate gene pathway platform. Arthritis and Rheumatism 56(12): 4164–4173.

Kozyrev SV and Alarcon‐Riquelme ME (2007) The genetics and biology of Irf5‐mediated signaling in lupus. Autoimmunity 40(8): 591–601.

Moonesinghe R, Khoury MJ, Liu T and Ioannidis JP (2008) Required sample size and nonreplicability thresholds for heterogeneous genetic associations. Proceedings of the National Academy of Sciences of the USA 105(2): 617–622.

Rhodes B and Vyse TJ (2007) General aspects of the genetics of SLE. Autoimmunity 40(8): 550–559.

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Nath, Swapan K, and Sawalha, Amr H(Jul 2008) Systemic Lupus Erythematosus: Genetic and Epigenetic View. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1002/9780470015902.a0006092]


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It is our desire for your children to walk in God’s truth and have a blast doing it. Your kids will have a great time playing games and doing activities. You’ll enjoy knowing that they are learning and practicing kingdom principles. They are learning to live in God’s presence, listening to His voice, and loving Him. They are learning to pray, ministering with power, and believing God for the impossible. They are learning that God has a plan for their life and walking boldly as a follower of Christ.

We offer infant and toddler care check-in beginning at 10:15 am. We have a director trained in First Aid, CPR, and safety policies and procedures. There’s a team of volunteers to help ensure that all your little ones are safe. One
of our hospitality volunteers will gladly show you to the room and help you with check-in. All volunteers have received a background check before being allowed to serve. Please contact Audrey Bryan for more information.

The children who are in K4-5th grade will be dismissed after worship so they can enjoy
corporate worship. Each Sunday your kids will have their own time of teaching, activities, and games. It is so much more than childcare. Your kids are being trained to pray with power, believe for miracles, and to be bold in their witness for God. The Childrens’ Ministers are Jeff and Leighann Lucas. They are amazing leaders with amazing heart, passion, and love for your children and they will be with your child every week! Please contact Leighann for more information.

Youth group

Our middle school and high school students join us in the service each Sunday. However, we also meet in groups at different homes and try to connect as many adults to our youth as possible. Different adults lead studies and facilitate the groups. We like our students to take an active role in teaching, ministry and serving on
e another. The group location may change from time to time but essentially we always incorporate faith, food, friendship, and fun. Our middle and youth students get together monthly for an activity. The past three months we went tubing, saw a movie, and competed against the adults in sports. To keep track of events for our youth check out our events page, contact the church office, and sign up for weekly email, called the Tuesday2


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Travel, Restaurants, and Sport

Dear Readers,

I have added this page on travel and sport, where I will give an impartial judgement concerning the airlines that I use, the hotels that I stay at, and sometimes the restaurants that I visit. I have also included sport which will cover mainly my passion for golf.

Unlike other travel websites, you can have at least the satisfaction of contacting me directly if you disagree with me.

If you have any comments of a similar nature, please do not hesitate to include them.

To start the ball rolling, I am more than happy to give the hotel “Golf View Hotel” in Nairn (about 15 minutes from Inverness Airport) 10 out of 10.

The rooms are clean and very relaxing, the food great, and being only 100m from the seashore, has a breath taking view.

The beach itself has golden sands, and permits very enjoyable walks.

There are two golf courses that are very close to the hotel (one only walking distance):

I would recommend this hotel whether for long or short stays. Take a look at the map and see for yourself, the place is full of places to visit.,+UK&hl=en&ftid=0x48857f60bce16edb:0x26f7d88216ab010e

My Golf Course – a home from home. Very close to the Lake of Garda.

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Our Latest Blog Posts
ATC Peoples Choice

Enhanced Greenhousing awarded People’s Choice award at Australian Technology Competition

Although we did not make the finals for The Australian Technology Competition we were still able to present and pitch at the ATC showcase. Our presentation was voted the most popular and we walked away with this great trophy. We also produced a new video explaining how Enhanced Greenhousing works This is our presentation Picture this. You are at home and you feel like a healthy snack. You…

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Enhanced Greenhousing ATC Press Release

Global potential for technology that powers greenhouses with organic waste A ground-breaking sustainable technology that enables greenhouses to increase crop productivity using power derived from their own recycled vegetable mass or external organic waste streams has become a semi-finalist in the 2017 Australian Technologies Competition (ATC). The Enhanced Greenhousing system, developed by Melbourne sustainable technology business Enesys, can be added to an enclosed greenhouse to provide closely controlled and flexible…

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What the Judges had to say

Winner of the 2016 Environmental Business Award, Nillumbik Shire Council. Enesys is the research and development arm of a 28 year old, highly successful Eltham North engineering business. Enesys has developed a control system called CubeLink which has the potential to become a global game-changer across a large variety of industries and products. Currently the control system is being tested in a pilot project that is enabling micro algae to…

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Saturday, October 23, 2010

Day 296 of 365

Today we finally had a full day to just hang out. We had breakfast and played for a little bit. Chelsea and I took the kids to a park to run around a little before the rain came. We ate lunch. The kids and Aunt Chelsea played the Wii and DS. It was a nice relaxing day.


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Shipwrecks of the River Murray

The depths of the River Murray hide a multitude of stories about South Australia’s maritime history.

In the late 1800s and early 1900s the River Murray was heavily used by pastoralists, settlers and travellers. Paddle steamers and barges regularly travelled back and forth carrying passengers and various goods including mail, fruit, wool, wood and livestock.

The ships were a way to connect the towns dotted along the river, which helped build the river community.

The South Australian Register of Historic Shipwrecks was created to keep track of these vessels, with ships that have been wrecked or decommissioned for 75 years added to the list.

It’s believed that about 77 shipwrecks lie beneath the surface of the River Murray in South Australia.

One ship recently added to the register is the S.S. Captain Sturt, a paddle steamer assembled at Mannum in 1916. If you’ve been to Goolwa, there’s a good chance you’ve spotted her paddlewheel sticking out of the water as the centrepiece to the Captain Sturt Marina.

The 35m-long ship was a vital part of the construction of South Australia’s locks and weirs, and the Goolwa Barrages.

Another shipwreck of note along the river is the Water Witch. A single-masted cutter built in Tasmania in 1835, Water Witch was the first European vessel to enter the mouth of the River Murray.

She was used to chart the lower reaches of the river, and was used by the explorer Edward John Eyre in his work. The ship was wrecked in 1842 and declared a historic shipwreck in 1983.

You can discover more about the shipwrecks of the River Murray by following the River Boat Heritage Trail. The trail was installed in 2009, and highlights listed shipwrecks along the river between Border Cliffs and Goolwa, telling the stories of the vessels, places and people.

To explore the Register of Historic Shipwrecks:

  • Visit NatureMaps
  • Select ‘Switch to Layer View’
  • Expand the ‘Heritage and Tourism option’
  • Select ‘Shipwrecks’

Image courtesy of the State Library of South Australia

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Women Changing Women's Worlds

Various Photographers

This photo series is created to mark International Women's Day (IWD) and features portraits of female activists, pioneers and change-makers who are transforming life for women around the world.

The women featured have all fought against the dominant structures in their worlds to help improve the lives of other women. The group includes an artist, various professors, athletes, grassroots activists and even a lone female mechanic working in the Lebanese countryside.

Despite the huge variations in their individual experience, all have a pioneering spirit that embodies the unifying themes of International Women’s Day.

PRISCILLA NANGURAI (08 November 1948) – Kenyan director of the Girls’ Rights, Attention, Care and Education rescue center

KEIKO OCHIAI (15 January 1945) - Writer, feminist, founder of Crayon House book store

ENI LESTARI (24 January 1978) - Hong Kong-based Indonesian domestic helper and labor rights activist

MARTINE PICCART (18 June 1953) - Professor of Oncology at the Université Libre de Bruxelles (ULB) and Head of the Department of Medicine at the Institut Bordet

RAJA CHEBBI (02 August 1961) – First Arab woman promoted to the rank of General in the Tunisian police

RIMA NASSER-TARAZI (22 March 1932) – Palestinian musician, composer, former President of the Administrative Board of the General Union of Palestinian Women

MYLENE KAMARA (14 March 1966) – Ivorian advocate for women's rights group West Africa Network for Peacebuilding

ANURADHA KOIRALA (14 April 1949) - Founder of Maiti Nepal, a rehabilitation and Orphanage home for HIV-affected children and women who are victims of trafficking

MONA YAAKOUB (05 October 1994) – Journalist, member of the ‘Fe-male’ and ‘Game’ associations

BERNICE FREEMAN (04 October 1967) - Liberian activist at Women in Peace Building Network (WIPNET)

AMINA AJOUCKA (18 October 1991) - Lebanese car mechanic

DHAMMANANDA BHIKKHUNI (06 October 1944) - Abbess Dhammananda of Songdhammakalyani Monastery

NADIA REMADNA (15 November 1959) – French social worker, founder of The Mothers’ Brigade

COURTNEY PAYNE-TAYLOR (born 1982) – US founder of the Girls Riders Organization (GRO)

LAXMI AGARWAL (01 June 1990) - Indian campaigner with Stop Acid Attacks

TENDAI GARWE aka SOKOSTINA (07 November 1982) - Zimbabwean feminist and radio personality

YE HAIYAN (born 1975) – Chinese gender activist and artist KHUSI KABIR (born 1948) - Head of Human Rights organization Nijera Kori

MARIJKE ALBLAS (30 June 1944) - Independent sexual and reproductive health and rights (SRHR) consultant, campaigner and abortion provider and trainer

MARIM ABDULLAH AL-QARDAE (22 January 1966) - Yemeni doctor and director of reproductive health service at the Health Qabil Center

ANAT HOFFMAN (born 1954) - Israeli activist, Women of the Wall founder

Photos by Daniel Irungu, Franck Robichon, Jerome Favre, Stephanie Lecoq, Mohamed Messara, Atef Safadi, Legnan Koula, Narendra Shrestha, Nabil Mounzer, Ahmed Jallanzo, Diego Azubel, Yoan Valat, Justin Lane, Harish Tyagi, Aaron Ufumeli, How Hwee Young, Abir Abdullah, Nic Bothma, Yahya Arhab and Jim Hollander.


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Top Menu

The Next Frontier for Computing: Computers that can Learn

Recently, a research team made a big big splash when they publicize that they’ve produced a machine that learns from its mistakes. There is only one organisms that we know of that actually learns from its mistakes in a very conscious manner. That organism would be us. That’s right, homo-sapiens. Be that as it may, it seems that we may be edging closer to self-aware machines sooner than we think. There is a lot of benefits to building machines that can learn. The problem with factory machines and computing machines that uses a fixed set of instructions to do certain things is that, situations change, the temperature is changed, circumstances can get quite random. In other words, life is what happens when you are making other plans. Unfortunately, all of our machines are currently using systems that enable them to behave in certain ways based on certain things that we can anticipate. So in other words, you program certain parameters into the software of the most sophisticated machine and its universe is restricted to those parameters. Thankfully, when you use the actual experience of the machine as a way of broadening those parameters, you can create machines that are more flexible and can produce the desired result. In a wide variety of circumstances, this can blow away current productivity. This can truly revolutionize how factories are run and how products are made.

While this computing model is great, one of the biggest changes that is staring the technology in the face is the possibility of quantum computing. Quantum computing is that instead of using zeros and ones and linear computing, you can factor in all sorts of possible solutions and possible pathways to a solution to a problem. In other words, it’s trying to use the way the human brain works. When you move your arm for example, it may seem obvious to you that you’re just moving your arm and that you translate your thought into action. However, for that to happen there are many different neuropathways that are engaged. If you, for example, suffer a stroke, it wouldn’t be as easy as before because you were moving your arm a certain way. You were using certain pathways. However, as you probably know, when you ask physical therapist, they have ways of having the brain rewind itself. Quantum computing and neuromorphic processing uses alternate pathways for processing solutions to the same problem. So, it’s kind of like a race to whichever pathway can produce the fastest result. This is revolutionary because this can build new efficiencies and more importantly, it can adapt to a wide range of changing circumstances. This is so amazing. This technology is so amazing that its actually quite scary.


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Friday, November 25, 2016

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Terrelle Pryor exiting OSU amid scandal

Terrelle Pryor's career at Ohio State, which started with so much promise and potential, came to an abrupt and scandal-ridden end.

The Ohio State quarterback announced through his attorney Tuesday that he would not play for the Buckeyes this season. He had already been suspended for the first five games for breaking NCAA rules by accepting improper benefits from the owner of a tattoo parlor.

"In the best interests of my teammates, I've made the decision to forgo my senior year of football at The Ohio State University," Pryor said in a statement issued by Columbus lawyer Larry James.

James said entering the next NFL supplemental draft is Pryor's "desire." But James acknowledged labor uncertainty could lead to consideration of the Canadian Football League or working with a personal quarterback coach first.

James said Pryor told him the decision was "in the best interest of my teammates."

The Cleveland Plain Dealer first reported Pryor's announcement.

The NCAA is looking into all aspects of Ohio State's once-glittering program, from cash and tattoos to players, car deals for athletes and other potential violations.

Pryor's announcement comes just eight days after Buckeyes coach Jim Tressel was forced to resign for knowing about the players' improper benefits but not telling any of his superiors.

"He did not want to be a a distraction to his teammates," James said of Pryor. "This is something he came to consider after much thought."

Ohio State's athletic director, Gene Smith, quickly issued a statement wishing Pryor the best.

"We understand Terrelle's decision and wish him well in this next phase of his life," Smith said. "We hope he returns to The Ohio State University one day to finish his degree."

Luke Fickell, who will serve as Ohio State's interim coach in place of Tressel this fall, found out about Pryor's decision on Tuesday night.

"I was notified this evening that Terrelle has decided to pursue a professional career," Fickell said. "I wish him the best in his pursuits."

Pryor's high school coach, Ray Reitz, said his former quarterback's move would be "probably best for everybody."

"Terrelle can get out of the spotlight and just play football," he said. "The sad part is, as a player, he was tremendous. It's just that all this will be a part of his legacy. It's a shame. I hope he gets a shot at quarterback in the NFL so he can prove people wrong. I think NFL teams want to win so I don't think they'll hold this too much against him."

Later Tuesday night, "Outside the Lines" reporters Tom Farrey and Justine Gubar reported that a friend of Pryor's, who requested anonymity, says he witnessed the quarterback autographing memorabilia in 2009-10 a minimum of 35 to 40 times and that Pryor netted anywhere from $20,000 to $40,000 last year for doing so.

The former friend told ESPN that Pryor was paid $500 to $1,000 each time he signed mini football helmets and other gear for a Columbus businessman and freelance photographer, Dennis Talbott.

"Outside the Lines" reported Talbott twice denied that he ever paid Pryor or
any other active Buckeyes student-athlete to sign memorabilia.

Pryor came to Ohio State on March 19, 2008, from Jeannette, Pa., as the most acclaimed high school quarterback prospect in the country. His career will be remembered in his adoptive home state for his three victories in as many tries against archrival Michigan, and victories in the Rose and Allstate Sugar Bowl.

But it also will be remembered for a series of missteps and controversies that seemed to follow the 6-foot-6, 233-pound physical specimen wherever he went and no matter what he said.

In the midst of an NCAA inspection into his cars, he drove a sports car to practice on the day that Tressel resigned. Even when it was shown that his mother had legally bought the car, which is four years old, many fans were angry. The fact that he was driving it made it headline news across the state and around the Big Ten.

On the field, Pryor was very good. He had a 31-4 record as a starter (starting one bowl game as a wide receiver), rushed for an Ohio State quarterback record 2,164 yards and passed for 6,177 yards. He was often at his best in big games, holding the school record with seven games with at least 300 yards of total offense and 22 games with at least 200.

But there were other moments that kept him from ever becoming a fan favorite.

He wore "Vick" on an eyeblack patch in honor of Michael Vick in 2009, after the NFL quarterback had been involved in a dogfighting operation. Pryor then infuriated many by saying, "Not everybody's the perfect person in the world. I mean, everyone kills people, murders people, steals from you, steals from me, whatever. I think that people need a second chance."

After Wisconsin beat the Buckeyes in October, handing them their only loss last season, Pryor petulantly said that Ohio State could beat the Badgers nine out of 10 times.

He also has called former Ohio State quarterback and current ESPN college football analyst Kirk Herbstreit "a fake Buckeye" for questioning Pryor's emotional sideline behavior.

Few NFL draft experts consider Pryor to be a ready-for-the-NFL quarterback. With his speed and size, he might be better cut out as a big wide receiver in the mold of Plaxico Burress.

Despite the NFL labor problems, a supplemental draft could still be held this summer, although no one has yet committed to entering it.

The NFL will not provide information on players that may have contacted the office about the supplemental draft, which has not been scheduled, a league source confirmed to ESPN.com's John Clayton.

Ohio State will go before the NCAA's committee on infractions on Aug. 12. With Tressel no longer with the program, along with Pryor who has been the most visible of those who were suspended, it was no surprise that Buckeyes fans expressed relief at Pryor's surprise announcement.

The Buckeyes have several choices to take Pryor's place. The most experienced player is fifth-year senior Joe Bauserman, with Kenny Guiton, Taylor Graham and talented freshman Braxton Miller competing for the job. All four got plenty of snaps in spring practice, since Pryor missed the April workouts after having surgery on his right ankle in January.

With Pryor no longer a college football player, he is no longer obligated to meet with the NCAA.

James would not comment on whether Pryor would continue to cooperate with the NCAA.

James said that Pryor was reflective when he made the decision to quit college football.

"You know how sometimes you have the weight of the world on your shoulders and then something like this takes a little bit off?" James said. "He's still only 21."

Information from The Associated Press, "Outside the Lines" reporters Tom Farrey and Justine Gubar, and ESPN college football reporter Joe Schad contributed to this report.


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Cary Artac’s market involvement began in 1986 as a trader-apprentice on the floor of the Chicago Board Options Exchange, where for several years he studied the complex relationship between option price behavior and underlying market activity. This formative experience provided an opportunity for Cary at the Chicago Board of Trade, where in 1989 he joined a team of 30 Year Treasury Bond futures traders, identifying for them option-hedging opportunities in the adjacent Treasury Bond options pit.

About Artac Advisory

Cary Artac, owner and principal analyst

Soon after his move to the CBOT Cary discovered a greater passion in accurately predicting the directional flow of the underlying Treasury Bond futures contract, and over the next several years extensively researched a wide array of analytical methods and formulas. During this time he came to comprehend the significance in fully studying all trend-timeframes, from hourly market data spanning several days to monthly data spanning several decades.

Cary sought to develop a technical process that provided accurate trend-identification results in correlation with highly specific price-support levels. The outcome has been a unique hybrid of classic and nontraditional charting techniques, supplemented by ample use of customized indicators – all blended into a discretionary trading system of consistent reliability. Merging the results effectively into a complete, interpretive system provides a heightened sense of market timing and directional flow – the very essence of harnessing profitable futures trading opportunities.

By the early 1990’s Cary’s daily analysis was sought after by a growing number of Chicago-based futures and options traders. Chicago Board of Trade grain and treasury traders, Chicago Mercantile Exchange stock-index, livestock, and currency traders, as well as Chicago Board Options Exchange stock-index option traders were managing risk and expanding profit potential through his daily market analysis. In 1996, with the increasing migration away from open-outcry and into electronic-market participation, Cary commenced web based delivery of Artac Advisory newsletters. And while he continues to provide daily analysis to a key number of floor trading operations, since the later 1990’s his clientele have become increasingly represented by risk management firms, brokerage houses, and commodity producers and wholesalers.

In 2012 Artac Advisory began production of the Monthly ETF Snapshot. With mid to long-term strategy the central theme, the Monthly ETF Snapshot keeps subscribers closely aligned with individual market-trends impacting over twenty popular, high-volume ETF’s. Every issue includes thoughtful commentary, descriptive chart illustrations, and highly specific price-support levels for each ETF analyzed. A year later Artac Advisory began producing the Weekly SPY Report, presenting a detailed technical analysis for the week ahead in the SPY (SPDR S&P 500 ETF). All of the trading and investment signals provided in both the Monthly ETF Snapshot and Weekly SPY Report are actionable through the ever-growing selection of high volume exchange traded products.

We encourage you to take our analysis for a test drive through our no-obligation two week free trial.  We’re convinced that after testing our daily analysis you’ll come to appreciate the clarity Artac Advisory can bring to your trading and investment strategy. If during the two-week trial you have any questions please don’t hesitate to call our office. We make ourselves fully available for phone consultation, assuring your comfort and understanding in making good use of our advisory newsletters.


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Ultimate Appointment Scheduling

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Guide to Koh Samui Wedding Venues: Say Yes to the Best Wedding Location

There’s the theme, the wedding dress, the music, wedding cake, so on and so forth. There are also the flowers, the invitations, souvenirs, food, and the honeymoon. Perhaps the most important consideration in every wedding is the location. This will determine all the other elements. For couples who are eyeing the island of Samui as a wedding destination, here are some pointers in choosing
among the Koh Samui wedding venues available.

The Date

Because of its idyllic beauty and inviting weather, more and more couples are signing up for Koh Samui weddings. Ideally, you should be able to have a specific date a few days after you got engage. This will give you more time to plan for the wedding and look for the best location that will suit your preferences. The nearer the date, the more challenging it would be to look for satisfactory Koh Samui wedding venues as chances are they have been already booked. The rule of the thumb is to plan early and look for wedding venues Koh Samui has to offer months in advanced. The most ideal months to get married in Samui is from November to February—its driest months. During this period, it is not too hot nor too cold and the chances that it will rain is very small. December to January is tourist pick season though so if you picked a date around this time, be very sure to book early.

The Honeymoon

Another consideration in picking Koh Samui wedding venues is the honeymoon. Ideally, the wedding venue and the honeymoon are one and the same. This is better especially if the couple wants to be able to celebrate on their own without having to travel after the reception. Actually, most wedding resorts have impressive wedding suites and very romantic ambience that is suited for both the wedding and the honeymoon. If the couple wants more privacy however, booking a separate venue like an intimate private villa is a better option.

The Guests

The number of guests is a huge factor in choosing a venue for Koh Samui weddings. If you want an intimate wedding, say a small size wedding where it’s just family, you don’t need a big space. However if it is a grand wedding you have in mind, you need a more elaborate venue. Because it is a wedding capital in Asia, Koh Samui boasts plenty of venues that can handle all kinds of weddings—big or small. Couples can choose to get married in a private property or a wedding resort. It does not matter as most Koh Samui wedding venues are flexible and workable.

The Theme

More and more people get married on the island and while it is natural to think that all couples prefer a beach wedding, others prefer a simple chapel wedding in a confined shaded area. Both are very different and have their own advantages. A confined wedding venue is easier to work with, meaning the lights and sounds are consistent and you don’t have the outside elements to battle with.

A beach wedding on the other hand is considerably a more enchanting experience, as you have the blue waters
and the scenery as backdrop.

However, a beach wedding requires even more planning as you have the weather conditions to consider. The choice is a matter of preference. If you’re a perfectionist and you want everything to be absolutely perfect and as planned, choose a confined, shaded wedding venue. If you want a bit of unpredictability and the scenery is very important for you, then you can decide to get married on the beach—with the elements in synergy. If you are looking for more customizable Koh samui wedding packages? Read this!

The Bottom Line

The wedding venues Koh Samui has to offer differ in size, the quality of the scenery, and amenities. They also come in a variety of prices. If you want a simple venue and you only have very limited guests, you won’t need to spend so much since you have plenty of options on your fingertips. However, if you have a grand wedding in mind, you might need to allot more budget for the venue. Don’t worry though as Koh Samui has less pricey venues compared to other wedding destinations in the world.

The Schedule

For locals, planning for a wedding is a lot easier since they know how to get around the island and will be able to plan on their own especially if a family member has done it before. For foreigners, planning might be more challenging. For those who cannot be on the island to attend to every aspect of planning for the big day, it is highly recommended to look for a venue with a wedding planning team. This will make the whole process easier and less stressful especially if you don’t have a lot of time to put everything together.

The Scenery

The reason why people get married in Koh Samui aside from the weather, is the scenery. The island is abundant in picturesque views that guests will never get enough of. As long as you are looking for the perfect wedding venue, be sure to head to the beach first hand and see if the ambience is right for you. Remember, you only get married once so your wedding must yield postcard worthy photos to show to your grandkids in the future.

The wedding location is at the heart of every wedding planning. The place where you choose to say your vows will determine the rest of the elements to make your dream wedding come true. Planning ahead of time is the best advice in choosing for a location. Keep in mind that the nearer the date of the big day means it is harder to book for Koh Samui wedding venues. If you don’t feel like stressing, remember to book early.


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Europe: Jihadists Posing as Migrants – “More than 50,000 jihadists are now living in Europe.”

Europe: Jihadists Posing as Migrants

“More than 50,000 jihadists are now living in Europe.”

  • More than 50,000 jihadists are now living in Europe. — Gilles de Kerchove, EU Counterterrorism Coordinator.
  • Europol, the European police office, has identified at least 30,000 active jihadist websites, but EU legislation no longer requires internet service providers to collect and preserve metadata — including data on the location of jihadists — from their customers due to privacy concerns. De Kerchove said this was hindering the ability of police to identify and deter jihadists.

German authorities are hunting for dozens of members of one of the most violent jihadist groups in Syria, Jabhat al-Nusra, but who, according to Der Spiegel, entered Germany disguised as refugees.

The men, all former members of Liwa Owais al-Qorani, a rebel group destroyed by the Islamic State in 2014, are believed to have massacred hundreds of Syrians, both soldiers and civilians.

German police have reportedly identified around 25 of the jihadists and apprehended some of them, but dozens more are believed to be hiding in cities and towns across Germany.

In all, more than 400 migrants who entered Germany as asylum seekers in 2015 and 2016 are now being investigated for being members of Middle Eastern jihadists groups, according to the Federal Criminal Police (Bundeskriminalamt, BKA).

The revelation comes amid new warnings that jihadists are posing as migrants and arriving from North Africa on boats across the Mediterranean and onto Italian shores. In an interview with The Times, Libyan Prime Minister Fayez al-Sarraj said that jihadists who had been able to pass undetected into his country were almost certainly making their way into Europe.

“When migrants reach Europe they will move freely,” said al-Sarraj, referring to the open borders within the European Union. “If, God forbid, there are terrorist elements among the migrants, any incident will affect all of the EU.”

Independent MEP Steven Woolfe said:

“These comments show the problem to be two-fold. Firstly, potential terrorists are using the Mediterranean migrant trail as a way of entering Europe unchecked. Secondly, with Europe’s lack of borders due to Schengen rules, once in Europe, they are able to move from one country to another freely. Strong borders are a necessity.”

Around 130,000 migrants arrived in Europe by land and sea during the first eight months of 2017, according to the International Organization for Migration (IOM). The main nationalities of arrivals to Italy in July were, in descending order: Nigeria, Bangladesh, Guinea, Ivory Coast and Mali. Arrivals to Greece were from Syria, Iraq, Afghanistan, Pakistan and Congo. Arrivals to Bulgaria were from Syria, Afghanistan, Iraq and Turkey.

In recent weeks, traffickers bringing migrants to Europe have opened up a new route BlackSeamapthrough the Black Sea. On August 13, 69 Iraqi migrants were arrested trying to reach the Romanian Black Sea coast, having set off from Turkey in a yacht piloted by Bulgarian, Cypriot and Turkish smugglers. On August 20, the Romanian Coast Guard intercepted another boat carrying 70 Iraqis and Syrians, including 23 children, in the Black Sea in Romania’s southeastern Constanta region.

A total of 2,474 people were detained while trying to cross the Romanian border illegally during the first six months of 2017, according to Balkan Insight. Almost half of them were caught while trying to leave Romania for Hungary. In 2016 only 1,624 migrants were detained; most were found trying to cross from Serbia to Romania.

Meanwhile, more than 10,000 migrants reached Spanish shores during the first eight months of 2017 — three times as many as in all of 2016, according to the IOM. Thousands more migrants have entered Spain by land, primarily at the Spanish enclaves of Ceuta and Melilla on the north coast of Morocco, the European Union’s only land borders with Africa. Once there, migrants are housed in temporary shelters and then moved to the Spanish mainland, from where many continue on to other parts of Europe.

ER recommends other articles by The Gatestone Institute

About the author

Soeren Kern is a Senior Fellow at the New York-based Gatestone Institute.  Follow Soeren Kern on Twitter and Facebook

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Allied Bank

The Bank Started Out In Lahore By The Name Australasia Bank Before Independence In 1942; And Became Allied Bank Of Pakis
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Askari Bank

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Introducing Kids to Programming and Video Game Design

Instructor: Johnny B Allen - Digital Media Designer & Owner of Evolving Creativity, LLC

Cost of Class: TBA

Class Meeting Times & Dates:

  • Class Location: TBA
  • Class Size: 5 to 10 students per session
  • Age Group: 2nd or 3rd grade (ages 7-9)
  • Required Materials: Headphones with mini headphone jack, needed to keep noise levels low.
  • Required experience: Students should already have had some hands-on experience using a computer(Windows, MAC, or Linux), tablet, or a gaming console to understand how to navigate in a web browser.

Why Kids Will Love This Class: This class will use video game-based learning to teach programming and computational thinking concepts in a fun way. The class will provide a combination of structured and open-ended activities that teach and allow students to create interactive projects.

Class Description: In this class students in 2nd or 3rd grade (ages 7-9) will learn to code and build awesome video games they can share and solve fun programming puzzles using the super easy coding platforms Tynker and CODE Studio. These easy to learn programming concepts will let students create almost anything they can imagine such as animating characters, making greeting cards, music videos, and fun video games.

Class Structure: Students will be using a web browser to visit two main websites to practice, learn, and save their programming projects/lessons. They will be given a print out containing their username and password and the website URLs to log in. Students will create unique digital media projects and games that they can share with friends and family. During class, students will watch short training videos before starting a lesson/project and a variety of other videos from professionals in the field to help them broaden their world of the programming industry. At the end of class, students will share their projects and have discussions about the coursework, video games, programming, and their aspirations for the future.

Goals & Rewards: Students will continue to have access to their projects so they can continue to work on them after the class and be able to share their projects with family and friends. Students will also receive a Certificate of Completion with their full name printed.

Student Handouts

Parent Handouts

Share this Educational Event

I think everyone should learn how to program a computer because it teaches you how to think.
— Steve Jobs, American entrepreneur at Apple & Pixar

Imagine, Program, & Share!

At the young age of 12, Thomas Suarez developed his own iPhone app "Bustin Jeiber", a whack-a-mole game.

Most 12-year-olds love playing videogames -- Thomas Suarez taught himself how to create them. After developing iPhone apps like "Bustin Jeiber," a whack-a-mole game, he is now using his skills to help other kids become developers. (Filmed at TEDxManhattanBeach.)


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