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Transforming Pathology

Improving cancer diagnosis using Artificial Intelligence

Research & Pharma

We have developed state-of-the-art approaches for the interpretation of immunohistochemistry in whole slide images. We are working with research labs and pharma companies to provide accurate, cost effective and scalable solutions.

Global Health

We aim to provide access to highly accurate pathological diagnosis at low cost in developing nations. We work with leading non-profit and government organizations to achieve this goal.

Clinical Diagnosis

We are developing tools to enable the use of artificial intelligence in clinical diagnosis of cancer and other diseases leading to faster, more accurate and reproducible results.

Deep learning is an algorithmic technique that is revolutionizing what is possible in areas such as finance, communication, automotive, natural language processing, computer vision and more. It allows computers to analyze vast amounts of data and automatically detect patterns and make accurate predictions.

Motivated by our success in a recent pathology competition (Camelyon Grand Challenge 2016), we are applying deep learning techniques to massive aggregated sets of pathology data to build algorithms to automatically detect and diagnose medical conditions – with the goal of helping hundreds of millions of people receive fast, accurate diagnosis.

Andrew H. Beck

Co-Founder & CEO

Andy earned his MD from Brown Medical School and completed residency and fellowship training in Anatomic Pathology and Molecular Genetic Pathology from Stanford University. He completed a PhD in Biomedical Informatics from Stanford University, where he developed one of the first machine-learning based systems for cancer pathology. He is board certified by the American Board of Pathology in Anatomic Pathology and Molecular Genetic Pathology. He joined the faculty of Harvard Medical School in 2011, where he is now an Associate Professor (Part-time). He has published over 85 publications in the fields of cancer biology, cancer pathology, and biomedical informatics.

Aditya Khosla

Co-Founder & CTO

Aditya is currently completing his PhD in machine learning and computer vision at MIT. He completed his MS at Stanford in 2011 and BS at Caltech in 2009. In his research, he has developed new methods for an array of applications in computer vision, including eye-tracking, prediction of image memorability, and visualization of deep networks. He is the recepient of a Facebook Fellowship and his work has been widely covered by various media outlets including BBC, The New York Times and The Washington Post. He has published over 30 papers in the fields of deep learning, computer vision and neuroscience.

We are always looking for exceptionally passionate, dedicated and talented individuals to join our team.

Email us at if you are interested!

Contact Us

We would love to hear from you! Fill out the form below or email us at


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The Genetics of Alzheimer's Disease: Are You at Risk?

Neurology Now
Fall 2005
Volume 1(3)
p 42–43
Back to top

If your mother, father, or grandparent has Alzheimer's disease (AD) are you also at risk?

Genetic screening may be able to tell you, but experts say it should only be used under specific circumstances.

“No one should be screened for Alzheimer's disease unless there is a very specific family history of the condition,” says Jill Goldman, M.S., a genetic counselor at the University of San Francisco Memory and Aging Center.

Genetic testing requires several one-on-one counseling sessions with a specially trained counselor, she adds. This counseling is necessary because the genetics of AD is complicated. “There are many genes we know are involved, and others we may not know about — and we don't have enough information about how different genes impact one another to easily determine risk,” she says.

In addition, counseling may be needed to help people grapple with the knowledge that they have an increased risk of a disease that is currently not preventable. While you may be armed with information about your genetic makeup, “there's nothing you can do in terms of preventing the disease,” says Thomas Bird, M.D., chief of the division of Neurogenetics at the University of Washington in Seattle. “The most valuable use of genetic screening under these circumstances is for family planning, financial planning and career planning.”

Late Onset AD

Age is the most important risk factor for Alzheimer's disease, a progressive, neurodegenerative disease characterized in the brain by abnormal clumps (amyloid plaques) and tangled bundles of fibers (neurofibrillary tangles) composed of misplaced proteins.

The most common form of AD is late-onset, meaning it develops after age 65; the number of people with the disease doubles every five years beyond that age. Only one gene has been identified so far as a risk factor for late-onset AD — a form of a protein called apolipoprotein E (APOE), which helps carry cholesterol in the blood. Researchers have found that the e4 type, or APOE e4, is associated with an increased number of amyloid plaques deposited in the brain.

Estimates of how great that increased risk is vary, so genetics experts are reluctant to give it a specific number. For example, a 2003 study in the New England Journal of Medicine estimated that inheriting a single copy of the APOE e4 gene may increase the risk by 50 percent over a lifetime. An earlier study (1997) in the Journal of the American Medical Association found that patients with two copies of the APOE e4 gene were nearly 15 times more likely to develop AD, whereas those with one copy were 2.6 to 3.2 times as likely. Not everyone with AD has the APOE e4 gene, and not everyone who has APOE e4 will develop AD. There is a commercially available test for the APOE e4 gene, but people should not take it unless they are experiencing disease symptoms, says Goldman. (See Box: Symptoms of AD.)

Box. Symptoms of Alzheimer's Disease

Click here to enlarge

Early Onset AD

Early-onset or familial AD — which affects only five percent of patients — is inherited and typically develops between the ages of 30 and 60, says Goldman. Researchers have identified three specific inherited gene mutations — alterations in the DNA of the genes that prevent them from working as they normally would — for early-onset AD: amyloid precursor protein (APP), presenilin 1 (PS1) and presenilin 2 (PS2).

If you have a parent with one of these gene mutations, you have a 50-50 chance of developing AD, explains Dr. Bird. If you have one of these mutations, you can get the disease as early as your 30s or 40s, he adds.

If your mother, father, sister or brother developed AD before the age of 60 and have symptoms of the disease, you should consider getting being tested for PS1. PS1 accounts for 50 percent of familial early-onset AD. There is a commercially available test to screen for the PSI gene.

If doctors do not find the PS1 mutation, you might consider being screened for the PS2 and APP genes. Goldman notes, however, that this is only currently being done in research trials. To find out more about those trials, go to the National Institute Aging at or .

If you suspect you have an inherited form of AD — and are not sure what to do — seek out advice from an expert before taking any test. “You need to consult with a genetic counselor or a doctor who is very knowledgeable about genetics and not go into this blindly,” Goldman says. To find a genetics counselor, ask your neurologist or contact the National Society of Genetics Counselors at (610) 872-7608 or visit .

American Academy of Neurology Foundation

The Brain Matters

Alzheimer's Disease Education and Referral Center

(800) 438-4380, (301) 495-3311

Alzheimer's Association

(800) 272-3900, (312) 335-8700

National Family Caregivers Association

(800) 896-3650, (301) 942-6430

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Day 16: more family fun

I guess I’m really going to need to work on my titles. This is the 2nd time this month I’ve come up with “family fun”. Pretty lame! Oh well, it’s true!

It’s really the only time they’ll let me take photos!

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graphic design of printing press and graphic design t shirts in toronto ontario. A freelance Photographer, illustrator, artwork, web templates, digital photographers and videographer working for advertising agency in toronto. visual art, graphic design by paul murton Canada

A Quick Pick Of
My Web Sites
Merchant Credit
Card Systems
Plastic Business Cards
Getting Found On The Web
CD DVD Duplication
toronto advertising agency
and yes I am a DJ as in Toronto DJ club/bar party music

Canada Guide Wedding Party Place Wedding

Canada freelance Photographer  toronto

CD Free

Credit Card Processing toronto - Graphic Arts - CD Covers- Photographer - Newspaper Lay-out - Web Design - Printing Costs - Marketing - Sales- Plastic BUSINESS CARDS Audio Visual Services - Radio Spots - Video Editor - Music DJ Bands - Sound Man - DJ -Booking Agency - Will check any POS debit card machine contract at no costs. Will show you where they are ripping you off

Canada graphic design
From paulmurton.com
E-Mail ( requires two e-mails )
Paul 416-693-8530
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(ScsanLife Free App)
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Home Of Paul Murton Toronto Canada

I sell POS credit card processing systems in Toronto. I'm a sales agent for torontocreditcardprocessing.com. I also sell wireless POS machine that take interac(debit card) anywhere a cell phone works. I also sell online merchant account for credit card processing.

I got here from being a graphic artist who sells printing of business cards for new small businesses. I became an expert in starting up a new business. More than happy to help you at no cost to you. As a graphic artist I work with a number of different services that all need a digital visual person. Graphic Lay-out - Audio Visual - Music - Credit Card Systems- Marketing - Sales - Printing Costs

marketing paul murton


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ron 97 feb 2014

Users of RON 97 fuel would have noticed an increase in the per litre price of the fuel earlier this month, when it was increased by five sen to RM2.85. The increase took place exactly a month from the last pricing change, which also saw a five sen increase to bring it to RM2.80 per litre. The hike took place quietly, so is this likely the start of a trend to tacitly go about working fuel pricing revisions concerning the unregulated premium fuel?

The current at-the-pump price for RON 97 thus takes it back to the pricing as of September 4 last year, when it was increased by 15 sen from its previous RM2.70, in place since May 23, 2013. Pricing of subsidised RON 95 and diesel has of course remained from its revision to RM2.10 per litre and RM2.00 per litre respectively from September 3 last year.


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Wednesday, August 6, 2014

Artist Profile: Jen Bergren

Welcome back, Jen! Jen Bergren ( participated in the Paws For Charity Project last year as well.You can find links to see Jen's photography at the bottom of this post.
Jen Bergren   (
Where do you live? What made you want to contribute to help raise funds for an animal shelter in Nova Scotia?
I live in San Diego. Paws for Charity not only raises money to directly benefit an animal shelter, but it also raises awareness in Canada, the U.S., and beyond for pet rescues and shelters in general, because of the publicity created by Sara and all the caring artists who contributed to it. I am proud to be a part of any project that raises people's awareness about pets in need and gets them thinking about adopting instead of buying pets, or thinking about fostering and other ways they can help.

Do you have a certain "style" in mind when you create your images?
My style is happy and colorful, often taking advantage of all the beautiful and varied locations that San Diego has to offer (beaches, parks, mountains, deserts, downtown urban...). I want people, especially the pet parents, to smile when they see their favorite images!

Tell us about a current project you are working on?
Last year I completed a creative project featuring dogs near San Diego neighborhood signs (including another installment this year), so the next personal project I am working on features San Diego area stairs and dogs. I have noticed an interesting variety of outdoor staircases around the area, and I think the hard geometric lines of stairs contrast nicely with furry round dog shapes, something similar that I discovered I liked last year when working on a San Diego Bridges (with dogs) project.

Thanks's great to have you involved again in this year's project!

All proceeds from the sale of these books are donated to Sheltering Helpless Animals in Distress (, an animal Shelter in Nova Scotia.
Click on this link to preview this year's book:

E-books are also can preview e-books here:

1 comment:

Unknown said...

Thanks so much for featuring me! Thanks even more for putting together all the Paws for Charity projects, Sara!


text:
 Home      Projects     Experiments     Circuits     Theory     BLOG     PIC Tutorials     Time for Science

This automatic 3.5'' floppy disk loader is really one of its kind! [Video]
posted April 6 2012 6:01.34 by Giorgos Lazaridis

Yes, i do have boxes filled with floppy disks, mainly 5 1/4'', but also 3.5''. Most of us have loads of those disks and data are slowly being lost. Here is what a creative dude thought...

[Via: hackaday]    [Link: dwellertech]
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Tags: crazy hack   rc servo   microcontroller   arduino   autonomous   creative   storage/memory   electronic project   computer peripheral hacks   mechanical   crazy designs   cool gadget   avr   hdd   pc related

The slinky-drop experiment in XXL [Video]
posted October 18 2011 8:06.06 by Giorgos Lazaridis

Some days ago i posted a new video from youtube user Veritasium, with a slinky-drop experiment. The same user uploaded a new video, again with the same experiment, but this time it...

[Link: Veritasium]
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Tags: experiments   pc related   storage/memory   physics   science   crazy photo/video   insane

IBM is developing the largest HDD ever
posted September 13 2011 7:59.57 by Giorgos Lazaridis

Do you think that your 1TB HDD is big? How about an 120 Petabute storage drive? One Petabyte is a HUGE amount of storage data and equals to 1.000 Terabytes. In other words, you will...

[Via: dvice]    [Link: Technology Review]
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Tags: hdd   storage/memory   crazy story   crazy designs   extreme   geek   omg

Insane programmers doing cool things with 1Kb
posted August 26 2011 10:26.46 by Giorgos Lazaridis

1Kb of data is not much. It is actually 1024 bytes, and if you suppose that each character is requires one byte, i've already spent 165 bytes to write this sentence. Yet some people...

[Link: js1k]
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Tags: simulation   software   storage/memory   games and fun   crazy designs   people with talent   geek

The first single-electron transistor is real
posted July 6 2011 19:09.26 by Giorgos Lazaridis

This great innovation will likely change electronics as we know: A team of researchers from the University of Pittsburgh managed to assemble a single-electron transistor, the first of...

[Link: science daily]
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Tags: research   new materials   science   pc related   extreme   quantum   storage/memory   inventions   pioneer   innovations   news

This 900GB 2GB/s PCIe solid state storage card is the one i want
posted June 11 2011 19:54.22 by Giorgos Lazaridis

Excellent, brilliant, and probably expensive. This is the new RamSan-70 PCIe SSD, which is said to offer up to 330,000 I/O operations per second read performance and 160,000 write...

[Link: gizmag]
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Tags: pc related   crazy story   crazy designs   cool gadget   extreme   insane   storage/memory

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Broadband Cable Association of Pennsylvania

April 15, 2014

Turner Broadcasting is getting a makeover.

For years, the parent company of cable channels TBS, CNN, TNT, Cartoon Network, HLN and TruTV was one of the more stable and low-key units of Time Warner Inc. Based in Atlanta, Turner seldom gets as much attention as Time Warner's Warner Bros. and HBO, despite being a cash cow that last year had operating profit of $3.5 billion and revenue of almost $10 billion.

But the new leaders at Turner - Chief Executive John Martin and President David Levy are shaking things up. There have been several high-profile departures this year - some voluntary and some not - and Levy has promised that more changes are in the works.

"Change is happening across our company now," Levy told Turner staffers in a memo Sunday. "These changes reflect a larger plan to evolve Turner for next-generation success and profitability. This effort will bring new voices to the conversation and reveal things we can and should do differently."

The most recent to exit is Steve Koonin, the president of Turner Entertainment Networks who Sunday announced that he is joining the Atlanta Hawks basketball team as chief executive and a co-owner. Koonin oversaw programming for all the Turner channels except CNN and HLN, which are news and talk outlets. Last month, Stu Snyder, the longtime head of Turner Animation, exited after six years. Also leaving as part of a restructuring was Greg D'Alba, the longtime head of CNN's advertising sales unit.

"Each departure had its own unique circumstance," Levy said in an interview, adding that Koonin had an incredible opportunity that is a "great fit for him." Levy also said despite talk of tensions between he and Koonin that "there's no bad blood or anything of that nature."

At the same time, Levy stressed a need for new ideas at Turner Broadcasting. "It gives us an opportunity for fresh thinking," he said adding that the unit has to "refocus ourselves." Of particular concern is TNT, which has struggled somewhat in developing hit original shows while rival cable networks including FX and AMC have found success with envelope-pushing programs such as "Sons of Anarchy" and "Breaking Bad," respectively. TNT's prime time audience has fallen more than 13% in the past five years to 1.9 million viewers from 2.2 million, according to Nielsen. Its median age is up to almost 52 from 47 during the same period.

TNT has had a more broad-based programming strategy and has tended to steer clear of the risque fare on many other channels. The network still hasn't filled the void left when its popular police drama "The Closer" ended two years ago. Its spin-off "Major Crimes" and "Rizzoli and Isles, another law enforcement themed drama, are successful, but a remake of "Dallas" started strong but faded and the odds of comeback are even longer since the death of star Larry Hagman last year.

Later this year, TNT will debut a legal drama called "Murder in the First," from famed producer Steven Bochco whose credits include "NYPD Blue" and "L.A. Law." Levy indicated that he is open to Turner having more cutting edge shows, but ratings rather than awards will drive strategy.

At TBS, which focuses on comedy, the network has also had problems developing breakthrough shows. But thanks to the popularity of reruns of the CBS hit "The Big Bang Theory," it has had solid ratings. This season, it is averaging 1.9 million viewers in prime time, up 8% from five years ago. It is also home to Conan O'Brien's late night show.

However, while TBS was the top network in adults 18-49 for the first quarter of this year, the median age for the channel has gone up dramatically from 36.4 to 43.6 over the last five years. Advertisers pay a premium for younger viewers.

TruTV's prime-time audience has tumbled more than 30% over the past five years. The channel focuses its efforts on unscripted fare, a very competitive arena.

The search for Koonin's replacement will not be limited to internal candidates, Levy said. Nor would the next executive necessarily work out of Atlanta, which was where Koonin was based. Both Levy and Martin spend the bulk of their time in New York and the next entertainment chief could be there or Los Angeles.

Although there has been speculation that Michael Wright, the president of programming for TNT and TBS may be on the way out too, Levy said Wright is a candidate for Koonin's job and "somebody we're going to look at for sure."

Besides better programming, the other major priority for Levy is locking down a renewal of TNT's deal with the NBA. TNT's current contract still has two seasons to go after this season, but the new sports channel Fox Sports 1 has made no secret of its desire to get the NBA.

"I certainly hope to continue that relationship," Levy said, adding "we're pretty entwined with the NBA." Levy knows that the next contract won't be cheap. "There is definitely going to be an increase," he said. - Los Angeles Times


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RPCV founded Nonprofit NY benefit

Peace Corps Online: State: New York: RPCV founded Nonprofit NY benefit

By Jeremy Conrad (user-0ccehfc.cable.mindspring.com - on Thursday, October 20, 2005 - 6:29 pm: Edit Post

I am an RPCV Senegal (2000-2002) currently attending Brooklyn Law School. This year I founded a nonprofit called Asylee Family Rescue Project. We raise funds to reunite political refugees with their spouses and children. Right now we are raising funds for a Mauritanian woman's rights activist living in New York.

Thursday October 27th we are having a fundraiser in Manhattan at QUO (www.quonyc.com) from 9-11 and I would like to invite anyone who can to attend. There is no cover (though donations are appreciated) and there will be free vodka drinks from 9-10.

If you would like to receive an evite invitation, want to donate or learn more, or would like to be contacted about upcoming events please feel free to contact me.

Add a Message

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Hawaii Peaks with 2000 feet of Prominence

Showing Bob Martin's first ascent dates for climbed peaks (2 out of 11, or 18.18%)

RankPeak Prom-Ft  Elev-Ft Range (Level 4)Isol-MiAscent Date
1.Mauna Kea13,79613,796Hawaii Big Island2452.5Unknown
2.Haleakala10,02310,023Maui Island Group75.4Unknown
3.Mauna Loa707913,679Hawaii Big Island25.2
4.Puu Kukui56685788Maui Island Group21.6
5.Kawaikini52435243Kauai and NW Hawaii203.4
6.Kamakou49614961Maui Island Group22.6
8.Lanaihale33793379Maui Island Group19.3
9.Hualalai30718271Hawaii Big Island22.3
10.Kaunu o Kaleihoohie25605480Hawaii Big Island16.8

Front Runners List: Click here to see list completion progress by climbers that log their climbs using Peakbagger.com.

Compare Climbers: Click here to compare ascents of up to 5 climbers working on this list.

List Description

List Info

The 11 peaks on this list break down as follows:
  • Six are island high points of the six major Hawaiian islands.
  • Two are a high point of the lower mountain range on an island composed of two very distinct ranges (Maui and Oahu).
  • Three are lower volcanoes on the Big Island, including Mauna Loa.

  • Prominence for the six island high points is, of course, equal to the elevation, so is easy to calculate.
  • Book County High Points by Andy Martin; list compiled 1999 by Edward Earl and Andy Martin.
  • List generation helped by Edward Earl's WinProm program.
  • Prominence values in this list may not agree 100% with sources, due to different interpretations of key col spot elevations and out-dated peak elevations in the PBC Database.

Map Showing Location of Peaks

 = Peaks climbed by Bob Martin   = Unclimbed peaks

Click on a peak to see its name and a clickable link.

(Map only shows peaks ranked by clean prominence)

Click Here for a Full Screen Map

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