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How Love Productions cooked up a recipe to save C4’s flagship show

A “mammoth sacrifice” from more than 120 people who entered a self-contained biosphere for six weeks enabled The Great British Bake Off to be safely delivered, according to senior Love Productions execs.

Earlier today, the Great British Bake Off account tweeted that ‘filming has wrapped’ on the autumn series of Channel 4’s flagship format, after staff were released from their tightly restricted bubble on Sunday.

The confirmation will have been met with relief at Horseferry Rd, with Love execs Kieran Smith and Letty Kavanagh breaking a long silence to reveal to Broadcast how the show got over the line in such challenging circumstances.

Creative director Smith said that Love was determined to enter production, despite strict lockdown restrictions, not least to ensure its small army of freelancers had a job as many other opportunities dried up. “So many people rely on Bake Off for work that we knew we had to work out a plan,” he said.

The Great Festive Bake OffW

In April, the pair began thrashing out a comprehensive blueprint that would enable the format to enter production and minimise the risk of being derailed by illness. Fears were understood to centre around the possibility of a contestant contracting the virus and having to drop out - threatening the continuity of the ‘whittle’ show.

Managing director Kavanagh quickly realised that Love could take advantage of the country’s emptying hotels and booked one exclusively for cast and crew – effectively creating a huge biosphere.

She alighted on Down Hall in Essex, which hosted the production ‘tent’ in its grounds, and supplied 20 hotel staff who entered the bubble alongside 80 Love staff and around 20 “children, chaperones and dogwalkers”.

Before entering the hotel, everyone was required to self-isolate for nine days and take three Covid-19 tests.

Transporting cast and crew from their homes to the production site was the next hurdle, with the routes forensically planned.

“We had to work out ways to the hotel so people wouldn’t need to use any public toilets,” Kavanagh said. “Moving people around in a sterile manner was the hardest thing.”

With full support from C4 and aided throughout by Love’s legal and compliance teams, who also entered the bubble, filming commenced in July.

A “gruelling” six-week shoot followed, with Love adopting a ‘two days on, two days off’ strategy. It was forced to eschew the typical shoot schedule under which the bakers are sent home for five days to practice between episode recordings.

“It was a massive operation, we even built 12 practice kitchens for the bakers to use on their days off,” said Smith.

Having been produced under such strict safety measures, the on-screen talent does not have to observe social-distancing guidelines, meaning viewers will be served a show that has no hint of lockdown restrictions.

The intensity of the experience meant producers were concerned about the mental health of crew, many of whom had gone from facing the prospect of having no work at all to a non-stop six-week schedule.

Kavanagh said they had experts on hand to support the crew throughout.

“It felt like the safest place in Britain,” she said. There was only a single Covid-19 scare, which ultimately proved negative.

She added that the baptism of fire was perfect for new host Matt Lucas to immerse himself in the format.

matt lucas

Matt Lucas: baptism of fire

“He was practically living with the bakers,” she said. “It felt like he had always been there.”

Love said that its ability to produce Bake Off in this manner proves that Covid-19 restrictions need not scupper filming shows of scale.

Chief executive Richard McKerrow paid tribute to all involved with the production.

“With everything everyone’s gone through this year, we thought it was vital to deliver the show,” he said.


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Site Navigation

Sunrise Double Hung Replacement Windows

Windows are an important part of any building you see around. From homes to businesses, windows are located in key areas of the facilities—used in different types and styles.

custom double hung windows

Some establishments come with double-hung windows, which are very beneficial for spaces that require a lot of ventilation and windows with less maintenance. However, if they get old or start to have leaks, you will need to replace all of them.

If you have any windows in poor condition and need appropriate solutions, you can trust Broward Impact Window & Door. We are a Sunrise, FL window and door replacement contractor that can tackle any window replacement requirement you may have. Whether you want us to put new double-hung windows on your old double-hung window areas or replace your current ones with double-hung windows, we can deliver and keep things affordable for your budget.

Call Broward Impact Window & Door at (754) 226-1614 for your Free Consultation!

Why Consider Double Hung Windows

double hung replacement windowsDouble-hung windows are the most popular type of windows seen in many homes and commercial spaces nowadays. Here are the reasons why they are popular and why you should consider them for your space:

1. They are available in various colors and sizes, which can fit any house theme or window opening. They are also available in many materials for better durability and varying finishes.

2. Double-hung windows are very affordable; they can be upgraded depending on your preferences such as the quality of glass used for the windows, etc.

3. These windows are also preferred for their energy efficiency. Reports suggest that homeowners get a 30 to 50% energy savings when they use these windows.

4. Less maintenance is needed for these windows because they can easily be tilted for cleaning. They don’t get damaged easily.

With these benefits in mind, it is safe to say that they will make a good investment for any place you want them to be. But, if you are still uncertain about it or you have any inquiries about these windows, let our team help you out. Our Sunrise double hung replacement windows experts can answer your queries and show you samples of these windows. We can also look into your space to see if double-hung windows fit your structure or not.

When to Replace Your Double Hung Windows

residential double hung windowsLike any other windows, double-hung windows must be replaced once they show signs of damage such as cracks, chips, discoloration, and wear. You should also replace them if you are remodeling or updating your home to keep things balanced and uniform with the rest of the house.

If you have double-hung windows, you need to look at the following to determine if you need to replace them:

1. If there are air leaks around the window due to weakening seals around its sides

2. If the hardware is no longer attached and working properly, causing the windows to fall after you put it up

With all these factors in mind, you need a professional team to get these windows replaced to secure your home. Our Sunrise double hung replacement window experts can come to your place to assess your windows’ state and recommend the best replacement for them.

Free Consultation Today

Broward Impact company logoFor any Sunrise double hung replacement window projects, you can trust Broward Impact Window & Door to handle it for you. Our team of replacement specialists will be on your property to deliver the best double hung replacement windows for your home or commercial space with your needs in mind.

Call us today to find out more about our services or get your answers to any inquiries you may have about double-hung replacement windows.

Call Broward Impact Window & Door at (754) 226-1614 today for your Free Consultation!

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text:
Bound To Stay Bound

View MARC Record
 Be the change : a grandfather Gandhi story
 Author: Gandhi, Arun

 Publisher:  Atheneum Books for Young Readers (2016)

 Dewey: 954.03
 Classification: Biography
 Physical Description: [38] p., col. ill., 28 cm.

 BTSB No: 365743 ISBN: 9781481442657
 Ages: 4-8 Grades: K-3

 Gandhi, -- Mahatma, -- 1869-1948
 Pacifists -- India -- Biography

Price: $22.16

With the help of his grandfather, Arun learns how every wasteful act, no matter how small, affects others.

 Added Entry - Personal Name: Hegedus, Bethany
 Illustrator: Turk, Evan

Download a Teacher's Guide

Accelerated Reader Information:
   Interest Level: LG
   Reading Level: 3.90
   Points: .5   Quiz: 184404
Reading Counts Information:
   Interest Level: K-2
   Reading Level: 2.70
   Points: 2.0   Quiz: 59029

   Kirkus Reviews (06/15/16)
   School Library Journal (+) (07/01/16)
 The Hornbook (00/07/16)

Full Text Reviews:

School Library Journal - 07/01/2016 Gr 2–6—Following Grandfather Gandhi, this title finds young Arun at his grandfather's ashram, or "service village." Slightly older now, the boy is working to adhere to the 11 vows of ashram living. Not wasting is the most difficult for him, and he has trouble understanding how this vow relates to nonviolence. Three incidents combine to help Arun learn the lesson. He accompanies his grandfather (Bapuji) on a trip and listens as he tells a crowd, "When nonviolence is accepted as the law of life, it must pervade the whole being and not be applied to isolated acts." On the way home, Arun tosses away a pencil stub. When Bapuji finds out, he sends Arun back in the dark to retrieve it, saying, "It is not the pencil, but you, that is important," meaning that Arun's grandfather loves him enough to hold him accountable. The third way that Grandfather teaches Arun is by helping him make a "tree of violence," a chart on the wall that shows how seemingly small actions or thoughts can lead to larger events. The illustrations, especially the visualization of Arun's tree, help children understand the weighty concepts. As he adds to it each day, it grows beyond the physical walls, dwarfing Bapuji and Arun and demonstrating that each decision takes a person on a particular path. The dramatic collage illustrations include dimensional elements to create the illusion of texture. The full-bleed spreads immerse readers and take them on the journey with Arun. Constantly shifting perspective moves from small to large and close to far, reiterating the theme of a small action having larger consequences. Another repeated motif is the use of frames within larger images to demonstrate connectedness. VERDICT This handsome book asks a lot of young readers but carries important messages delivered in a personal and relatable manner.—Lucinda Snyder Whitehurst, St. Christopher's School, Richmond, VA - Copyright 2016 Publishers Weekly, Library Journal and/or School Library Journal used with permission.

View MARC Record


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Bubs® Australian Goat Milk Follow-on Formula Stage 2 Bubs® Australian Goat Milk Follow-on Formula Stage 2 Bubs® Australian Goat Milk Follow-on Formula Stage 2

Bubs® Australian Goat Milk Follow-on Formula Stage 2

Bubs Goat Milk Stage 2 Formula is exclusively formulated for tiny Australian tummies aged 6 to 12 months.

Our Goat Milk Stage 2 Formula, which uses fresh Australian Goat Milk, now includes more Omega 3 (DHA), Omega 6 (ARA), and Prebiotics (GOS).

Goat milk naturally supports gentle digestion and may be a good alternative for formula fed babies with sensitive tummies. Bubs premium formulation contains DHA and ARA from plants for improved taste.

  • Wash hands first. Sterilise bottle and teat in boiling water or a steriliser.
  • Potable, previously boiled water should be used. Pour the required amount of cooled boiled water into the bottle.
  • Add the required number of softly packed level scoops according to the feeding guide, using the provided scoop and the built-in leveler on the Can. Always add 1 scoop of powder for each 60mL of water.
  • Shake well until powder is dissolved. Test temperature on your wrist before feeding. It should feel lukewarm, not hot. Once prepared, serve immediately.
  • Each bottle should be prepared individually. If a bottle of made up formula is to be stored prior to use, it must be refrigerated and used within 24 hours. Formula left after a feed must be discarded.

Goat Milk Solids (Goat Full Cream Milk Solids, Goat Whey Protein Concentrate) 38%, Lactose, Vegetable Oil Blend (Canola Oil, Sustainable Palm Olein Oil, High Oleic Sunflower Oil, Sunflower Oil, Coconut Oil), Galacto-Oligosaccharide (GOS), Docosahexaenoic Acid (DHA), From Algae), Arachidonic Acid (ARA), Emulsifier (SoybeanLecithin), Choline Bitartrate, Inositol, Antioxidants (α-Tocopherol, Ascorbyl Palmitate), Taurine, L-Carnitine.

Vitamins: Sodium Ascorbate, dl- α-Tocopheryl Acetate, Niacinamide, Vitamin A Acetate, Cholecalciferol, Cyanocobalamin, Calcium Pantothenate, Folic Acid, d-Biotin, Thiamine Hydrochloride, Riboflavin, Phytonadione, Pyridoxine Hydrochloride.

Minerals: Sodium Chloride, Ferrous Sulphate, Calcium Carbonate, Sodium Citrate, Magnesium Sulphate, Potassium Chloride, Calcium Phosphate, Inositol, Zinc Sulphate, Potassium Phosphate, Taurine, Copper Sulphate, Manganese Sulphate, Sodium Selenite, Potassium Iodide.

Serve size: 22

Average amount per 100 mL of made up formula
Energy 278kJ
Protein, total 2.0g
- Whey protein 50% 1.0g
- Casein protein 50% 1.0g
Fat, total 3.3g
- Linoleic Acid 479mg
- Alpha-Linolenic Acid (ALA) 42mg
- Docosahexaenoic Acid (DHA) 7.6mg
- Arachidonic Acid (ARA) 5.4mg
Carbohydrate 7.2g
Sodium 26mg
Vitamin A 63µgRE
Vitamin B1 - Thiamin 97µg
Vitamin B2 - Riboflavin 157µg
Vitamin B3 - Niacin 546µg
Vitamin B5 - Pantothenic Acid 371µg
Vitamin B6 - Pyridoxine 59µg
Vitamin B12 0.35µg
Vitamin C 10mg
Vitamin D 0.99µg
Vitamin E 1.2mg dl-α-TE
Vitamin K1 3.9µg
Folic Acid 14µg
Biotin 3.6µg
Calcium 61mg
Copper 46µg
Iodine 12µg
Iron 0.91mg
Magnesium 7.1mg
Manganese 10µg
Phosphorus 42mg
Selenium 2.1µg
Zinc 0.53mg
Chloride 93mg
Potassium 87mg
L-Carnitine 1.5mg
Taurine 5.0mg
Choline 9.5mg
Inositol 6.3mg
Galacto-Oligosaccharide (GOS) 334mg
Shipping Information

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text:
BucketBall - Rainbow Edition - Combo Pack

List Price: $69.99
Regular price $ 59.99 $ 49.99 Sale

Fast Shipping 60 Day Money Back Guarantee Safe and Secure Checkout

BucketBall™ is the ultimate beach, poolside, backyard, camping, tailgating and outdoor game family and friends love playing.

The BucketBall Rainbow Edition gives you bucket colors of the rainbow: red, orange, yellow, green, navy blue, purple.

The BucketBall™ - Rainbow Edition - Combo Pack Includes:

  • 12 Ultra-Durable BucketBall™ Buckets of the following:
    • 2 Red Buckets
    • 2 Orange Buckets
    • 2 Yellow Buckets
    • 2 Green Buckets
    • 2 Navy Blue Buckets
    • 2 Purple Buckets
  • 2 BucketBall™ Hybrid Game Balls
  • 2 BucketBall Bucket Pong Balls
  • 2 BucketBall Tailgate Game Balls
  • BucketBall™ Tote Bag
  • BucketBall™ Instructions

Our BucketBall™ Combo Pack includes all three types of BucketBall game balls: Hybrid Balls, Bucket Pong™ Balls, and Tailgate Balls. The different game balls provide different game play experiences and different levels of difficulty. Our Hybrid Balls are perfect for playing at the beach or when filling the buckets with water. They are extra bouncy, will float on water, and are our most challenging game balls. Our Bucket Pong Balls provide a beer pong like game play experience. They are the same ball to bucket size ratio as compared to a red solo cup and a ping pong ball. These also float on water and provide an intermediate game play experience. Our Tailgate Balls are perfect for playing on flat/hard surfaces. They do not bounce or roll far making them perfect for use at tailgates, camping, indoors, outdoors and other events. Since they do not bounce, these balls are great for beginners as well. In addition, these balls allow you to play without filling the buckets with water, sand or some weighted object.

We also offer a BucketBall™ - Rainbow Edition - Party Pack which includes our inflatable rack set and duffel bag.

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text:
Bisley Original Cotton Drill Work Pant-(BP6007)

SKU: BP6007-Navy-74L

or make 4 interest-free payments of $9.98 fortnightly with Afterpay More info

  • Mobile phone pocket on right side
  • 7 reinforced belt loops
  • Single front pleats
  • Back patch pockets
  • 2 side angled pockets
  • Coin pocket in waistband
  • YKK zipper

100% Cotton Preshrunk Drill 310gsm

Download FactSheet

Size Chart
  1. NECK Measure around the neck where the top of the short collar would sit.
  2. CHEST Standing naturally, measure around the fullest part of the chest and shoulder, under the arms with your arms at resting position.
  3. WAIST Measure over undergarments at the natural waistline ( usually approx. 1cm below the navel ).
  4. Measure from crotch to floor, with shoes.

Size REGULAR 77R 82R 87R 92R 97R
To fit waist size (cm) 77 82 87 92 97
To fit waist size (inches) 30 32 34 36 38
Inner leg (cm) 80 82 82 84 84

Size REGULAR 102R 107R 112R
To fit waist size (cm) 102 107 112
To fit waist size (inches) 40 42 44
Inner leg (cm) 86
86 88

Size STOUT 87S 92S 97S 102S 107S
To fit waist size (cm) 87 92 97 102 107
To fit waist size (inches) 34 36 38 40 42
Inner leg (cm) 78 80 80 82 82

Size STOUT 112S 117S 122S 127S 132S
To fit waist size (cm) 112 117 122 127 132
To fit waist size (inches) 44 46 48 50 52
Inner leg (cm) 84 84 84 84 84

Size LONG 74L 79L 84L 89L 94L
To fit waist size (cm) 74 79 84 89 94
To fit waist size (inches) 29 31 33 35 37
Inner leg (cm) 85 85 87 87 88

Shipping & Delivery

Once receive the order, our team will verify the following information “ Name, address, payment information, next we will check availability of the items with the supplier and then process the order. We try to keep our inventory upto date as per our suppliers but there could be times when items are on back order and may not be available. We will let you know the exact ETA and if is acceptable to you, we will process the order or will give you a full refund if the ETA is not acceptable.

We do not hold any stock, and all these Items are shipped from our warehhouse in Moorabbin, Victoria, Australia.

Orders are shipped between 4-5 working days upon receipt for items that are in stock.For items that are not in stock, an ETA will be provided by the customer service team.

Shipping costs by Australia Post /NZ Post

Order Value Freight INC GST
$0-$150.00 $11.00
$150 -$300.00 $15.50
$300.00 - $500.00 $17.50
Orders above $500.00 Free

Our preferred method is Australia Post Eparcel for all orders that leave from our  Moorabbin Warehouse in Melbourne store. Please see parcel delivery time frames here http://auspost.com.au/parcels-mail/delivery-networks.html

 Pricing, Taxes, Fees, Other Charges

All prices are excluding GST as these items are being exported from Australia.

New Zealand customs duty and GST will be applicable on every order.This will need to be paid by the receiver of the goods and Budget Workwear will not be responsible for it.

Please calculate the cost of duties and taxes before ordering. For more information please see below

Refunds & Exchanges Policy

  • The validity of our refunds and exchanges policy is 7 days from the day you have received your order and is applicable only to un-decorated garments ( non embroidered, non screen printed)
  • While placing an order online with embroidery, make sure that you have selected the right product, size, and color, because once the items are decorated, we cannot exchange or accept returns.
  • The un-decorated product must be unused and in the exact same condition that you received it, in its original packaging with all the swing tags on it
  • To return or exchange please click here and follow the instructions on screen.
  • Shipping charges that may be applicable while returning products should be paid by you and are non-refundable.
  • You are also welcome to use our pre-paid label at a cost of $15.00 which will be deducted from the amount that is owed to you.
  • if you are using your own carrier, It is advisable to use a track able shipping service or purchase a shipping insurance while returning items, as we cannot guarantee you that we will receive the item you returned.
  • After receiving the returned item, we will inspect it and notify you whether we have approved or rejected your refund or exchange.
  • If approved, we will issue you with a store credit or refund as per the option that you choose while making the return.
  • Store credit can be used anytime on our website for exchanging sizes or buying other items of your choice.


text:
European Clay Powder - 6 oz

European Clay Powder - 6 oz
(You save $2.34 )
(1 review) Write a Review
Calculated at Checkout

European Clay Powder - 6 oz.

  • Facial Detox / Most Skin Types

Condition:  Normal, combination and oily skin types in need of detoxification, as well as smaller pore size.

Solution:  European Clay Powder is 100% Pure and Natural and can be mixed with water and customized to your specific skin type.  This mask will help draw out impurities from the pores and remove debris from under the skin, decreasing pore size and improving skin tone.

Suggested Usage

For oily skin, mix 1 tablespoon of NOW® European Clay with 1 tablespoon of cold water. For dry skin, add a few drops of NOW® Jojoba Oil and/or NOW® Lavender Essential Oil to the mix prior to applying. Thoroughly cover the face and neck avoiding sensitive areas and the eyes, allow to set for 15-20 minutes, rinse off and apply moisturizer. Always do a test patch when using essential oils. For external use.

This product is guaranteed to be 100% natural.

NOW Foods does not test on animals.

Please Recycle.

1 Review

  • 5
    Good Stuff

    Posted by Nancy from TX on 3rd Feb 2017

    I have only used this once, but I really liked it. I usually buy Queen Helene Mint Julep face mask and it always dries up before I finish the jar so I end up wasting it This was really nice because I can just mix the dry powder with water when I want to apply a clay mask. No waste! It made my oily skin feel nice and refreshed and really soft and clean. I think it's a great product. Very pleased!


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Bulk Cheap Ammo

Data last updated on 2020-11-24 @ 15:49:13pm(EST)

One-stop website to find in-stock ammunition, guns, magazines, and reloading components.

Disclaimer: Links on this website go to affiliate websites, which means we get a commission if you buy the products from these links. That helps us to keep the website free for all customers.


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phone icon 1300 BULL18
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cleaning services
Bull18 Cleaners > cleaning services in langwarrin

Get Free Cleaning Quote

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Cleaners Langwarrin | Bond Cleaning | End of Lease Cleaning

cleaners LangwarrinA popular joke among housewives is that the secret to a clean home is never letting your children or husband enter in. On a more serious note, everyone will agree that maintaining cleanliness in any facility, be it domestic, commercial or a corporate is no laughing matter. In fact, it is a time consuming, tedious, and boring task that is best handled by experts!
Bull18 Cleaners is happy to take the dreaded load off you! We specialize in the full line of house cleaning, office cleaning, or carpet cleaning services that rob you of time and energy. With us in charge, you can rest assured that your premises will always look spotless and pristine.

High Standards of Vacate, move in Move out & Bond Cleaning Langwarrin

In terms of delivering the most experienced clean-up services, we are number one in the industry. And your reputation doesn’t rest only on popularity. We at Bull18 Cleaners strive hard to provide the best in class Move out customer service, high standard of workmanship, and 100% satisfaction to our valued clients. Equipped with the latest technology, our experienced and professionally trained team is proficient at tackling any cleanliness related problem with the utmost ease. We care immensely about our environment and only use non-toxic vacate cleaning materials and safe methodology. And our tailor-made solutions are wallet-friendly.

Full Range of End of Lease Cleaning Services in Langwarrin

Bond Back Cleaning LangwarrinWe at Bull18 Cleaners have been delivering a huge range of professional end of lease cleaning services to satisfy clients throughout Langwarrin, Melbourne. Our mission is to take care of the nitty-gritty’s so that you don’t have to. No matter how big or small the setup, we have the expertise and the technical prowess to clean well and clean right. Whether it is a tough commercial job, freshening up the venue after a late-night party or some window polishing just give us a call and we’ll be there to help.

Our Specialized Capabilities

  • Office Cleaners Langwarrin
  • Window Cleaning
  • Commercial Cleaning
  • End of Lease
  • Move in/Move out Cleaning
  • Upholstery (wet and dry)
  • Carpet Steam Cleaning
  • Carpet Cleaners Langwarrin

Flexible and Tailored

At Bull 18 Cleaners, we customize cleaning packages to best fit your needs, schedules, and preference. Our team is operational 7 days a week and offers flexible services based on your specific requirements. We provide regular cleans, one-off cleans, end of tenancy cleans, and before/after party cleans. You can also engage our service for any frequency, be it monthly, weekly, fortnightly, several times a week whatever suits you!

Bull18 Cleaners Services in Langwarrin, Melbourne

end of lease cleaning LangwarrinIf you want to be part of the busy and vibrant scene, Langwarrin, with its pub culture, chic cafes, and an abundance of eateries is a fantastic place to reside. But there is more to Langwarrin than an awesome nightlife. The suburb has great public transport, trendy shopping malls and is close to all of Melbourne’s sporting venues. Bottom line is that Langwarrin is an ideal location for professionals and students. Our focus at Bull 18 Cleaners is to make lives healthy, clean, and dirt-free for all in Langwarrin. Contact us today at 1300 BULL18 and bestow all your cleaning woes onto us.

Copyright © 2013-2020 Bull18 Cleaners Pty Ltd. All rights reserved.


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Cetaphil Moisturising Cream - Bumps n Baby

Cetaphil Moisturising Cream

  • A rich, fragrance-free moisturiser that delivers intense hydration and  replenishes even the driest skin into soft, smooth and healthy skin.

NOTE: Currently due to COVID lockdown online deliveries may be delayed, however you can always find Cetaphil products at the nearby Chemist Store!


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Bungalows (A/C & Foxtel)

Containing a master bedroom with a queen-sized bed and a second bedroom with two sets of bunks beds and a sizeable wardrobe, in addition to being located a short distance from the BBQ and playground area, our Bungalow is the ultimate family-friendly accommodation. Like the Spa Villa and Treetop Spa Lodge, this accommodation boasts a fully self-contained kitchen that is situated next to the living and dining area in an open-plan style that makes for the perfect family communal space.

The features of this area are certainly not lacking either: a reverse cycle A/C unit, ceiling fan, radio and TV (Foxtel included) and DVD player. The Bungalow is also home to a bathroom that is spacious (in part due to the separate toilet) and contains a hairdryer and washing machine, catering to the needs of both parents and children of all ages. You can also enjoy your personal piece of the paradise that is Burrill Lake with the kitchen-accessible verandah and outdoor setting that leaves no part of this amazing location to the imagination.

  • Master bedroom with Queen bed
  • Second bedroom with 2 sets of bunks
  • Reverse cycle air-conditioning
  • Ceiling fans
  • Bathroom
  • Separate toilet
  • Full size kitchen
  • Spacious dining and living area
  • Full length verandah with outdoor furniture
  • Foxtel
  • Hairdryer
  • TV, DVD, CD/radio stereo system
  • Washing machine

Travelling With Pets

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When Corporate Defendants Go on Offense [Subscription required]

In defending against an $18 billion judgment levied by Ecuadorean courts, oil giant Chevron has played more offense than defense. It has sued the plaintiffs' U.S. and Ecuadorean attorneys, and several of the plaintiffs' expert witnesses. Last month, Chevron even filed counterclaims alleging fraud and misconduct by Patton Boggs, a well-respected U.S. law firm involved in the case. While unusual, Chevron's "offensive" defense strategy is beginning to pay off, and it may offer a playbook for future corporate defendants facing foreign lawsuits they view as abusive…Litigation in foreign courts may become more common for American multinationals because the Supreme Court has severely restricted lawsuits in U.S. courts arising out of overseas conduct. Yet as Chevron discovered in Ecuador, corporate defendants may face much more dangerous litigation in foreign jurisdictions. [Also refers to Petroecuador, Texaco (part of Chevron).]

Part of the following stories

Perfil de las demandas judiciales contra Chevron/Texaco por actividades en Ecuador

Opinion piece analyses Chevron's strategy in defending against $18 billion judgment in Ecuadorian oil pollution lawsuit


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Huge demand created by people shopping at home during the lockdown has led parcel delivery giant DPD to announce it is creating 6,000 new jobs and opening new depots.

The company is investing £200 million this year to expand its next-day parcel capacity, including £100 million on vehicles, £60 million on 15 new regional depots, and the remainder on technology.

With daily headlines of redundancies elsewhere the business said it is looking for drivers, warehouse staff, managers and mechanics, to work across the UK, with most of the recruitment in place before October - ahead of Black Friday and the Christmas peak.

Most of the jobs are full-time, with drivers having the option of signing up to the self-employed contract the company has run for more than 20 years.

DPD said even before lockdown restrictions were announced in March, demand for its delivery service had risen significantly as people started increasing their reliance on online shopping.

DPD is forecasting the growth to continue this year, despite shops reopening.

Chief executive Dwain McDonald said: "We are experiencing the biggest boom in online retailing in the UK's history and we are making this unprecedented investment in our infrastructure and people to ensure we can continue to meet the high levels of demand for our services.

"DPD has been one of the fastest growing major companies in the UK in the last 10 years due to the growth in e-commerce, but what we have seen in recent months is potentially a much more significant shift in behaviour, and we believe elements of it will be permanent.

"As a company, we've been dealing with rapid growth and ongoing investment cycles for a long time, but this is a very significant moment.

"I do think the high street will bounce back from where things are now, but we have to base our modelling on our conversations with retailers and their projections.

"It looks like there will remain a much greater reliance on e-commerce in the future - that's going to be our 'new normal'."

Employment minister Mims Davies said: "Clearly many sectors continue to feel the impact of Covid-19, but there are opportunities in other sectors and growing areas.

"These jobs span several regions of the UK and are hugely welcome as we switch our focus to renewing and rebuilding our country.

"Not only is this positive news for the jobs market but also the economy, with signs people are spending and increasing demand for logistics.

"With roles ranging from drivers to mechanics to managers, these positions are open to jobseekers with a range of skills and provide fresh options for those seeking employment."


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#google#Twitter#Dick Costolo#Promoted Accounts#Accenture#acquisition#blogger#co-founder#evan williams#Feedburner#product strategy#Pyra Labs#Bayer Loses Patenting Fight In India

Twitter CEO steps down, COO comes in

|Oct 5|magazine4 min read

In an announcement on the Twitter blog, Twitter co-founder Evan Williams stepped down from his post as CEO and asked Twitter COO Dick Costolo to take the reigns over. In the blog, Williams discusses how well the company is faring from when the website came to fruition and how he will remain with the company and be completely focused on “product strategy.”

Williams writes, “When I insisted on bringing Dick into the COO role a year ago, I got a lot of questions from my board. But I knew Dick would be a strong complement to me, and this has proven to be the case. During his year at Twitter, he has been a critical leader in devising and executing our revenue efforts, while simultaneously and effectively making the trains run on time in the office.”

Williams was also co-founder of Pyra Labs, the creators of Blogger, in 1999 and ran the company until its acquisition by Google in 2003. Williams took over the CEO position at Twitter in 2008 and helped to grow the company into a 165 million user social media platform with 300 employees and a billion dollar valuation.

Costolo’s expertise resides in helping companies create revenue and spent seven years as a consultant for Accenture. He was also the CEO of FeedBurner, before it was acquired by Google in 2007.

Recently, Twitter has focused on generating revenue and turning the website into a viable business, all while expanding its reach of service globally as much as possible. Coincidentally, Twitter launched Promoted Accounts services in order to gain revenue from businesses and individuals looking to gain a larger following.


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'A disgrace': Donald Trump goes after Ted Cruz's father

Donald Trump took several swings Tuesday morning at Sen. Ted Cruz’s father, Rafael Cruz.

Speaking by telephone with “Fox and Friends” on Tuesday, the Republican presidential candidate took issue with Cruz’s father recently suggesting to an audience of Christian voters in Indiana that Trump’s hypothetical presidency “could be the destruction of America.”

“I think it’s a disgrace that he’s allowed to do it, I think that it’s a disgrace that he’s allowed to say it,” Trump said of Cruz.

He continued: “It’s disgraceful that his father can go out there and do that, and so many people are angry.”

Trump also pushed back against the elder Cruz’s pitch to evangelical voters, pointing out high-profile endorsements from figures like Liberty University President Jerry Falwell Jr.

During Tuesday’s interview, Trump also sought to undermine Rafael Cruz’s legitimacy by parroting a dubious National Enquirer story. The story claimed Rafael Cruz was photographed in the early 1960s handing out pro-Fidel Castro leaflets with President John F. Kennedy’s assassin, Lee Harvey Oswald.

Various news outlets have cast doubt on the legitimacy of the Enquirer, which has endorsed Trump and has published a series of suspect stories critical of the Texas senator.

Trump’s comments came the day of the Indiana primary, in which the Republican frontrunner is looking to score a knockout blow against Cruz. Though Cruz has campaigned hard in the Hoosier State, most recent polls show Trump with a significant lead.

NOW WATCH: Ted Cruz just released a bizarre attack ad featuring a terrifying Hillary Clinton impersonator

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Butterflies and Moths of North America

collecting and sharing data about Lepidoptera

  Sighting 442656

Observation date: June 07, 1984
Data source: Heitzman, J. Richard
Submitted by: legacy.reporter (Heitzman, J. Richard)
Specimen type: Specimen
Collection location: Heitzman, J. Richard
Observation notes: As "Markham Springs Nat. Cmpg." on JRH data card.
Status: Unknown
Verified by: legacy.verifier (Phillip Koenig; Heitzman, J.R.)
Verified date: March 10, 2009
Coordinator notes: None.
Checklist region(s): Wayne County, Missouri, United States


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The Canons

Updated: Jul 28

We are excited to be involved in the redevelopment of The Canons House & Grounds in Mitcham.

This community project has been awarded monies raised by National Lottery players and awarded through the Heritage Lottery Fund (HLF) and Big Lottery Fund. The house, grounds, dovecote, pond and recreation ground are owned by Merton Council, who will be undertaking the project.

The National Lottery funded project will run for two years and includes both a major capital works project and a series of events and activities focused on community engagement.

Buxton will be involved in the refurbishment of Canons House a 17th Century Grade II* Listed Georgian House and the restoration of a 500 year old chalk block Dovecote built circa 1511.

We will also be adding a new Café Extension to Madeira Hall and carrying out hard landscaping works adjacent.

Employer: Merton Council

Employers Agent & Architect: Simpson & Brown

Project Manager: Greenspaces

PQS: Faithful + Gould Ltd

Connect with us

Buxton Building Contractors Limited

Cedar House, 91 High Street

Surrey, CR3 5UX

Telephone. 01883 348921

Our head office reception is currently

(click for hours)

Please use our fast form to get in touch

online-appointment (1).png


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Why Men Lose Their Edge

Feeling tired all the time?

Lost the motivation to reach your goals?

Struggling to get back in shape?

Once your past your 30's, things change.

Don't worry it's not just you and it's not your fault - life comes quick, and after decades of work, travel, raising a family and stress from all over, your body takes a beating.

Meanwhile your testosterone levels keep declining, leaving you feeling like someone you don't even recognize anymore.  (That's why every guy over 40 says: "It's a lot harder to get in shape now than it used to be.")

And when you make the choice to make a change - something to bring your edge back -  you'll quickly find that nearly everything has one or more of these huge flaws.

Powerful Natural Ingredients

Order by Phone:  800-542-8410

We Took The #1 Most Powerful Source Of Natural Testosterone On The Planet And Harnessed It --

Then Created A Men's Formula!

Use ANDROGENESIS to Restore:

Sex Drive // Vitality // Lean Muscle

3 Critical Problems With Men's Formulas

You Cant Ignore

Contains No Androgens

How is a product going to increase your testosterone levels if it's ingredients don't actually contain testosterone?  If you're not supplementing your testosterone, what are you really doing?

Insignificant Dosage Amounts

Even if the herbs inside the competing products did actually boost your testosterone, they require enormous concentrations and dosages to have any effect whatsoever - rendering them essentially useless.

Full of Dangerous Stimulants and Fillers

Many testosterone supplements fill their servings with stimulants like coffee, tea, etc. to load you with jittery energy. But this makes things worse: Stimulants often have a crash and can affect your sleep. Worse, some of these supplements even sneak in banned substances

So What Would The "Ultimate" Men's Formula Look Like?

We’re committed to taking male performance and ambition to new dimensions. So when it came to creating Androgenesis, our vision was simple: Create a rigorous, highest-performing supplement for dramatically better results.

We meticulously worked to create the key components in our one-of-a-kind exclusive formula by merging the very latest technology and cutting-edge scientific developments with time tested ingredients and knowledge.

You know what you’re getting and why you’re getting it (and not because of guesswork or budgets). More energy all day — without stimulants — by using ingredients scientifically optimized to transform your body’s production of ATP (your body’s cellular fuel) and testosterone, as well as create a supplemental source to draw from.

Even more essential vitamins and several of the best extracts available in men’s health for an unparalleled formula.

We just wanted to create a high-performance supplement for remarkable and uncompromising results.  And we did just that.

The Most Powerful, Most Advanced Testosterone Booster On The Planet

Welcome to the big league. This is the unrivaled scientifically-backed formula to safely maximize your testosterone levels, help you increase lean muscle, and explode your performance — no matter what your age.

  • Reinvigorate your daily life with high-level passion, energy, and drive

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  • Enhance your muscle-building potential and get the most out of your fitness

  • Elevate your body’s own testosterone production for remarkable, comprehensive results

  • Enjoy the trust of outstanding attention-to-detail and rigorous quality

This is the next-level formula for hardworking, ambitious men who want to be their best — and feel like the best is yet. ANDROGENESIS is a testament to our commitment to greatness: Bigger, better, and more-advanced.

Be among the many to experience a new world of potential. Reserve your free bottle of ANDROGENESIS today.

Unrivaled Scientifically-Backed Key Ingredient

Pinus Sylvestris Extract - A Gamechanger For Male Performance

Testosterone.  Yes  testosterone has been found in the pollen of the Scots pine (Pinus sylvestris).  Containing 80 ng/g of testosterone, 110 ng/g of epitestosterone, and 590 ng/g androstenedione per gram, our extraction method concentrates this by up to 2,000%.  Learn more about the Testosterone contained in pine pollen here.

"Pine pollen works in a different – and arguably more effective – manner than many other androgens because it actually contains phyto-testosterone. This means that it can directly provide testosterone to the body’s endocrine (hormonal) system and benefits can be experienced relatively quickly. It may not provide immediate results like steroids, but it will provide results in a more sustainable and less dangerous way." - Testogen

Androgenesis Natural T-Gel also boasts these endocrin essentials for Men:

Vitamin B6

Vitamins D & E

L - Arganine

Men Over 40:  Revitalize Your Body And Transform Your Life

Androgenesis Natural T-Gel is scientifically engineered to revitalize the complete range of men's performance, combat the natural male decline in testosterone, and transform what natural aging means - and feels like.

Packed with 22 amino acid's containing more than 100 enzymes, and more than 15 vitamins and 30 minerals, along with all the essential fatty acids as well as its androgenic content make Androgenesis more than a simple supplement.  Androgenesis transforms lives.

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The advanced formulation of Androgenesis electrifies your performance and endurance in the gym and helps you build more lean muscle. Get the most out of your training, carve a head-turning body, and enjoy the seemingly endless health benefits.

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Restore your youthfulness

Want more passion, motivation, and excitement? Our clinically studied key ingredient delivers more drive and desire so you can feel like you’ve turned back the clock on your body and regain the bounce in your step again.

Ignite the bedroom

With more testosterone and vitality, your benefits go beyond your health and fitness. Enjoy more libido, stamina, and confidence, exhilarate in your love life, and make yourself (and your partner) very happy.

Unique and one-of-a-kind, Androgenesis stands above the rest.

Our  cutting-edge technology, and unparalleled science revitalizes your body’s own testosterone production — completely free of banned substances and unnecessary, ineffective filler .

Explore the Cutting Edge Results of Androgenesis Natural T-Gel

Before Androgenesis

Bound free-t has proteins attached that prevent it from entering cells for use

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More free-t is available to use by cells that need it.

The Unrivaled Men's Formula With Unmistakable Scientific Support

Reserve Your Free Sample of Androgenesis Natural T-Gel Today

Virtually every other supplement wants you to pay upfront. Then, if it doesn’t work, MAYBE you can get SOME of your money back. (Good luck arguing with them.)

But why? You test drive a car before you buy it — why can’t you test drive a supplement? That way, you can see if you like it first before committing.

We’re so confident in our cutting-edge formula, science, and technology, we want to send you a sample to try so you can experience its benefits — no obligation.

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Enter Your Details Below

You must act now in order to get your exclusive free sample. This offer is limited to one per household. Must be 18 or older. If you qualify for this exclusive online offer, your order will be shipped in 24-48 hours. Act now to get your free sample of Androgenesis in just a few days!

We strive to provide the best science backed products that deliver the best results possible.

  • Easy access to customer service by emailing support@phytogenesislabs.com.

  • Your trial will ship within 24 to 48 hours.

  • Great Products. Discrete shipping. Cancel anytime.

 Privacy Policy  |  Cookie Policy  |  Terms And Conditions   |   Contact   |   Returns

These statements have not been evaluated by the Food and Drug Administration.

This product is not intended to diagnose, cure, treat or prevent any disease.


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ANDROGENESIS natural testosterone gel is a new testosterone gel and is available without a prescription.

It is produced from the concentrated ethanol extract of wild harvested pine pollen from the forests of Northern Michigan and the Canadian Northwest. Scientific studies have proven that pine pollen contains various male androgens including Testosterone, DHEA, Androstenedione and Androsterone.

It's gel form ensures critical compounds are absorbed into the body and not destroyed by the stomach.

ANDROGENESIS is admistered topically to upper shoulder and stomach area twice daily.

Pine Pollen and Testosterone

Scientific Studies prove pine pollen is filled with actual male hormones. These studies have shown it has actual testosterone, not a mimetic or something similar, but the actual androgenic hormone that's in our bloodstream naturally.  The Pinus Syverstis veriete for example contains: 80 ng/g of testosterone, 110 ng/g of epitestosterone, and 590 ng/g androstenedione.  ANDROGENESIS is 2,000% more concentrated than raw pine pollen alone.  Learn more about the Testosterone contained in pine pollen here.

Additional Benefits of Pine Pollen

Pine pollen is also a complete protein with 22 amino acid's Containing more than 100 enzymes, and more than 15 vitamins and 30 minerals, along with all the essential fatty acids.  It is also the richest known source for testosterone boosting plantsterols and brassinosteroids.  Learn more about the contents of pine pollen here.

On top of it's androgenic qualities, pine pollen also has known and proven Anti-aging effects.  Learn more about pine pollen's Anti-aging effects here.

AndroGenesis Natural Testosterone Gel Product Label

Click image to enlarge

Click image to enlarge

  1. Bio-identical phytoandrogens in the pollen of Scotch pine P. silvestris L. (Li J, Zhang Z, 1971 )

  2. Vitamin D and its metabolites in the pollen of pine. Part 5: Steroid hormones in the pollen of pine species. Pharmazie. (Saden-Krehula M, Tajíć M.1987)

  3. Androgenic and Anabolic Effects of Pinus tabulaeformis Carr Pollen in Clarias gariepinus. (Ausussto S Jr,  2017)

  4. Effects of Pine Pollen Extract in Relieving Hot Flushes in Sex Hormone-Deficienct Rats.  (Thisayakorn, 2017)

  5. Plant Hormone Cytokinins for Modulating Human Aging and Age-Related Diseases. (Jiří Voller, 2017)

  6. The Plant Hormone Abscisic Acid is a Prosurvival Factor in Human and Murine Megakaryocytes. (Malara A, 2017)

  7. Immune-Enhancing Effects of Taishan Pinus massoniana Pollen Polysaccharides on DNA Vaccine Expressing Bordetella avium ompA (Fujie Zhu, 2016)

  8. Effect of pine pollen extract on experimental chronic arthritis; (Axenov-Gribanov DV, 2016)

  9. Analysis of human food safety and laxative function of pine pollen Wen Ping Jing, 2016)

  10. The protective effects of Masson pine pollen aqueous extract on CCl4-induced oxidative damage of human hepatic cells. Jin X, 2015)

  11. Characterization and Biological Activity of Taishan Pinus massoniana Pollen Polysaccharide In Vitro (Shifa Yang, 2015)

  12. Actinobacteria possessing antimicrobial and antioxidant activities isolated from the pollen of scots pine; (Gen-Xiang Mao, 2012)

  13. Antiaging Effect of Pine Pollen in Human Diploid Fibroblasts and in a Mouse Model Induced by D-Galactose (Gen-Xiang Mao, 2012)

  14. Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning, Yanhong Luo, 2012)

  15. Mechanisms of natural brassinosteroid-induced apoptosis of prostate cancer cells. Steigerová JFood Chem Toxicol. 2012)

  16. Brassinosteroids inhibit in vitro angiogenesis in human endothelial cells (LucieRárová, 2012)

  17. Brassinosteroids and analogs as neuroprotectors: Synthesis and structure–activity relationships Author (JihaneIsmaili, 2012)

  18. Rapid effects of novel phytoandrogen adjuvant therapy (PAT) onmetabolic health: a gender, age and BMI matched case-control study (Ong YC, 2011)

  19. Anabolic effect of plant brassinosteroids. (Debora Esposito, 2011)

  20. Oxidative activation of indole-3-acetic acids to cytotoxic species— a potential new role for plant auxins in cancer therapy. (Lisa K.Folkes, 2011)

  21. Brassinosteroids cause cell cycle arrest and apoptosis of human breast cancer cells. (Steigerová, 2010)

  22. Anti-fatigue Effects of Flavone in Pinus Massoniana Pollen on Mice (WU Jing-jing,2010)

  23. Antioxidant and antiinflammatory activity of pine pollen extract in vitro. (Lee KH. (2009)

  24. Model Induced by D-Galactose Pine pollen polly-sacchrided on reactive oxygen species,(Lee KH1,2009)

  25. The phytohormone auxin induces G1 cell-cycle arrest of human tumor cells. (Ester K, 2009)

  26.  Allergenicity and cross-reactivity of pine pollen. (Gastaminza G, et al. ,2009)

  27. Anticancer and antiproliferative activity of natural brassinosteroids (JanaMalíková, 2008)

  28. Abscisic acid is an endogenous stimulator of release from human pancreatic islets with cyclic ADP ribose as second messenger. Bruzzone S, 2008)

  29. Antinociceptive and anti-inflammatory activities of pine (Pinus densiflora) pollen extract. ( Wang YM, 2007)

  30. Effects of pine pollen polysaccharide and its sulfate on the production of ROS in cardiomyocytes (Geng Yue, 2007)

  31. Effective Components and Pharmacological Function of Pine Pollen (He Xiaoyan, 2007)

  32. Chen Wei; Study on Extraction and Determination of Choline in Pine Pollen ( Li Ying ;2006)

  33. Pine pollen hits cell defense Yan Zhenli, 2006)

  34. Analysis of pine pollen by using FTIR, SEM and energy-dispersive X-ray analysis. (Guang Pu, 2005)

  35. Interventional effects of pine pollen in rats with hyperplasia of prostate, (T. Cong, 2005)

  36. Analysis of pharmacological effects and clinical application of pine pollen in combination with other Chinese patent formulas in clinical trials. (In benign prostatic hyperplasia: Wang Fuchang, 2004, and in primary hypertention, Hu Guocan et al 2005)

  37. The mechanism and clinical application of pine pollen. (Zhao Lixin, 2004)

  38. Transition from a botanical to a molecular classification in tree pollen allergy: implications for diagnosis and therapy. (Mothes N, .2004)

  39. Roux KH, Teuber SS, Sathe SK. Tree nut allergens. Int Arch Allergy Immunol. (2003)

  40. Multiple pollen sensitization: a molecular approach to the diagnosis. (Mari A, 2001)

  41. Biphasic effect of nitric oxide on male hormones and cyclic GMP production by purified rat Leydig cells cultured in vitro (Sandra Valenti, 2001)

  42. Pine pollen allergy in northern Arizona. (Freeman GL. 1993)

  43. Antiviral effect of brassinosteroids against herpes virus and arenaviruses. (Wachsman MB, 2000)

  44. Analysis of pharmacological effects and clinical application of pine pollen. (Sheng wise et al, 2018)

  45. Vitamin D and its metabolites in the pollen of pine. Part 5: Steroid hormones in the pollen of pine species. (Saden-Krehula M, 1987)

  46. Test. and androgens in hormone in royal jelly.  (J. Vittek, 1986)

  47. Clinical study of chrome-rich pine pollen in the treatment of type 2 diabetes, (Fang Zhaohui, see Translation 2019)

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© 2020 Phytogenesis Laboratories, LLC.  All rights reserved.

The health information contained herein is provided for educational purposes only and is not intended to be a replacement for discussions with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider.

This product has not been evaluated by the FDA and is not intended to treat, prevent or cure any disease or medical condition.


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Police Are Searching For Person Of Interest In Pokémon Go Killing

Police released a sketch of a person of interest in the fatal shooting of a 20-year-old who had been playing Pokémon Go at the Aquatic Park in San Francisco.

Last updated on September 28, 2016, at 9:35 p.m. ET

Posted on August 8, 2016, at 4:21 p.m. ET

Police released a sketch Wednesday of a person of interest connected to the fatal shooting of a 20-year-old man playing Pokémon Go at San Francisco's Aquatic Park in August.

The man in the sketch was seen leaving the scene of the shooting in a Toyota Avalon, police said.

The victim was identified as Calvin Riley, a resident of San Mateo, according to the San Francisco medical examiner's office. Riley was fatally shot sometime between 9 and 10 p.m., at the western end of Aquatic Park, located on the city's northern waterfront and part of the San Francisco Maritime National Historical Park, Lynn Cullivan, a park spokesperson, told BuzzFeed News.

Sgt. Robert Jansing, a detective with the U.S. Park Police, told the Los Angeles Times that the gunman did not take any of Riley's belongings or attempt to rob him.

"There doesn’t appear to be any outstanding motive right now,” Jansing said.

Riley was playing Pokémon Go on his phone when he was shot, a family member said on Facebook and on a GoFundMe account set up for Riley's funeral expenses.

"As of now all we know is Calvin was shot randomly while playing Pokémon Go," his cousin Gabriel Antonio Morales said on the fundraising website.

Riley's family moved from Massachusetts to California a few years ago, Morales said on Facebook.

Another family friend, John Kirby who claimed to be speaking on behalf of Riley's parents, told KGO-TV that Riley and his friend was among a "large group of people playing Pokemon" at the park.

"Calvin got a little bit ahead of his friend and kind of went around a corner," Kirby said, adding that Riley and his friend noticed someone watching them from the top of a hill overlooking the park, but it was dark and they were focusing on their cell phones while playing the game.

"Then when the friend came around a corner he heard a gunshot, saw his friend fall, and whoever did it ran away and possibly got into a car," Kirby told KGO-TV. "From what we know there was no confrontation. There was nothing said back and forth. It was just senseless, just came up and shot in the back and ran away for nothing," he said.

Cullivan said he was aware of the reports about Riley playing Pokémon Go before he was shot, but he could not comment as it was an ongoing investigation.

The United States Park Police (USPP), who is investigating the incident along with the San Francisco Police Department, is requesting anyone "who may have witnessed suspicious behavior" in the Aquatic Park area to contact them.

The USPP did not return a BuzzFeed News request for comment and the San Francisco Police Department declined to comment.

Riley, a star baseball player in high school, was a pitcher for the Mustangs baseball team at San Joaquin Delta College. His baseball coach, Reed Peters, said in a statement that Riley was "a fun loving teammate that players loved to be around."

"Calvin was loved by all those that knew him," Peters said. "He was a great person from a great family; a 20-year-old with his best years ahead of him...Calvin Riley brought out the best in all of us."

"I know you moved out there to pursue your dreams of one day making it to the league and you had all the mechanics, talent and dedication to make your dreams a reality," Morales wrote on the GoFundMe page. "But all that was taken by a coward who wanted to shoot up a poké stop."

Want to see more stories like this? Become a BuzzFeed News member.


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Who searches for "business valuation" the most?

Here’s a weird fact:  Doug Twitchell and Nathan Struk at BVR did an analysis of the people who searched for “business valuation” on Google for all years (2004 to present).   The city with the most searches?  Mumbai!  (Portland, OR, was second–perhaps BVR staff trying to find themselves, or Shannon Pratt trying to track the growth of the profession?) And, since January 2010, the country generating the most searches for “business valuation?”  Australia.  Let us know if you can make any sense out of these tidbits…open a branch office in Perth?


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Matt Kulick

26 Matt Kulick

  • Height:
  • Weight:
  • Year:
  • Hometown:
  • High School:
  • Position:

SPORTS PLAYED AT BW (YEARS AND LETTERS WON): As a junior in 2012, Matt competed in his third season of baseball and earned his second varsity letter.

ATHLETIC HONORS: As a junior in 2012, Matt was named as the "Yellow Jacket Award" recipient. The Yellow Jacket Award is given annually to the exemplary baseball student-athlete who has demonstrated a year-round dedication to the team by displaying a positive attitude toward the game and his teammates and showing a strong work ethic and a style of unselfish play and leadership. This award was voted on the by the B-W Coaching Staff.

GENERAL BASEBALL INFORMATION: Matt has had a solid baseball career thus far. B-W has recorded a 56-53-1 record during his first three seasons in the Brown & Gold. For his career, Matt has played in 28 games, including 10 starts, and is a .273 hitter (15-for-55) with eight runs scored, three doubles and 10 RBI. In the field,. he has committed just one error in 67 fielding chances.

As a freshman in 2010, Matt played in his first season of baseball and earned a certificate of participation for his efforts. He saw playing time at catcher on junior varsity squad.

As a sophomore in 2011, Matt played his second season of baseball and earned his first varsity letter. He appeared in 16 games, starting ten of them between catcher, first base and third base. He hit .205 (8-of-39) on the season with a .360 on-base percentage, four runs scored, one double and six RBI. Defensively, Matt had a perfect fielding percentage, making no errors in 53 chances. B-W finished the season at 17-17.

As a junior in 2012, Matt played in his third season of baseball and earned his second varsity letter. He appeared in 12 games, but did not start any of them. Matt hit .438 (7-for-16) with four runs scored, two doubles, and four RBI. B-W finished with a school-best 27 wins for a record of 27-13. For his efforts, Matt won the Yellow-Jacket Award, recognizing an individual whom displays excellence on and off the field.

DO YOU BELONG TO ANY OTHER CLUBS OR ORGANIZATIONS AT BW: Matt is a member of the Night on The Town staff as well as a member of the Accounting Association.

HIGH SCHOOL SPORTS PLAYED (YEARS & LETTERS EARNED): Matt played four years of baseball and earned two varsity letters. He played golf for three years and earned two letters and basketball for one year, but did not letter.

HIGH SCHOOL HONORS, SPECIFY SPORT & YEAR: (ALL-CONFERENCE, DISTRICT,  ETC.): As a senior in baseball, Matt was named as a first-team All-Principals Athletic Conference performer, runner-up for PAC Player of the Year honors, he was also named as his team's Most Valuable Player, Offensive Player of the Year and there Falcon Award winner for his great leadership. Statistically as a senior, Matt hit .380 with 25 hits, nine runs scored, five doubles, one homerun, 15 runs batted-in, a .476 on-base percentage and .500 slugging percentage. In golf as a senior, He received the Falcon Award for his great leadership on and off the course.


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Why Chiropractic?

Chiropractic is a natural alternative health care profession. Chiropractors perform adjustments (manipulations) to the spine or other parts of the body. The goal is to correct alignment problems, ease pain, and support the body's natural ability to heal itself. They may also use other treatments including

  • Heat and ice
  • Electrical stimulation
  • Relaxation techniques
  • Rehabilitative and general exercise
  • Counseling about diet, weight loss, and other lifestyle factors
  • Dietary supplements

Many people visit chiropractors for treatment of low back pain, neck pain, and headaches." Source: MedLinePlus/NIH

"The term “chiropractic” combines the Greek words cheir (hand) and praxis (practice) to describe a treatment done by hand. Hands-on therapy—especially adjustment of the spine—is central to chiropractic care. Chiropractic is based on the notion that the relationship between the body’s structure (primarily that of the spine) and its function (as coordinated by the nervous system) affects health.

Spinal adjustment/manipulation is a core treatment in chiropractic care, but it is not synonymous with chiropractic. Chiropractors commonly use other treatments in addition to spinal manipulation, and other health care providers (e.g., physical therapists or some osteopathic physicians) may use spinal manipulation." Source: National Institutes of Health

Princeton's newest Chiropractor Dr. Justin Mathis is committed to helping you get pain relief caused by spinal joint dysfunction issues to better your health and lifestyle through corrective care and management. Come see us today and experience the difference!!!

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As part of Alberta's relaunch strategy, we are able to resume offering our full range of services, effective May 4, 2020.

At this time, social distancing measures are still in effect and as such,  we cannot accept walk-in patients, or walk-in inquiries.

Additionally, we require all patients arriving at the clinic to wear face masks. Please note, we are unable to provide face masks, so we kindly ask that patients arrive prepared.

If you have any questions about our infection prevention and control protocols, or would like to book an appointment, please call for 403-289-8491.

Shockwave Therapy for Tendon Disorders in Calgary

Shockwave therapy is used to treat a number of bone, joint and tendon disorders. Shockwaves are generated pneumatically and spread through tissues in a radial fashion. At North Hill Foot & Ankle Clinic, Dr. Crosby offers this therapy for tendon disorders in Calgary. Shockwave therapy is thought to work by creating a micro trauma to the area of treatment which:

  • Stimulates blood vessel formation and blood vessel dilation
  • Causes release of pain mediators that decrease pain
  • Causes release of growth factors that aid in tissue regeneration
  • Causes anti- inflammatory effects

Shockwave therapy can be used to treat a variety of bone, tendon, and joint disorders, some of which include:

  • Plantar fasciitis
  • Achilles tendonitis
  • Shin splints
  • Patellar tendonitis
  • Peroneal tendonitis
  • Non-union of fractures

Non-surgical Therapy Procedure

Painful foot disorders can be treated with effective and non-invasive procedures.

Book an Appointment

General Information

North Hill Foot & Ankle Clinic
271-1632 14 Avenue NW, Calgary, AB,

T2N 1M7

Phone : 403-289-8491

Fax : 403-282-4441

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Monday 08:30 AM - 04:30 PM

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Calgary Real Estate reviews REALTORS®

Jonn VanBryce Reviews

Jonn VanBryce Calgary REALTORS® reviews

Jonn VanBryce 53 4.5

VERIFIED Customer Review

Carol and Jeff Knudsen - Oct 21 2019

Overall: full star full star full star full star full star 5/5
Experience: full star full star full star full star full star 5.00/5
Competency: full star full star full star full star full star 5.00/5
Knowledge: full star full star full star full star full star 5.00/5
Communication: full star full star full star full star full star 5.00/5

The McKelvie Group provided professional and efficient service during our sale process right from the initial meeting through to the sale of our home in Bearspaw. Printed and electronic media were top rate and Kelly's knowledge of the market was excellent. We were kept in the loop and communication from the office was great. Overall a very positive experience and would not hesitate to use them again.

Jonn VanBryce REALTOR®

Working as a licenced Realtor Jonn VanBryce provides strategic marketing and transaction management to his clients. Building his business on Passion, Dedication, and Hard work Jonn has successfully helped many clients to sell their current property and find the perfect new home. He is an ambitious agent who has gained years of industry related experience working with landscape design, construction, and home staging. Born and Raised in Calgary his knowledge of the city and its geography will assist you in all your Residential Real Estate endeavours. “I strive to go above and beyond for my clients. I ensure to listen to their needs and wants, doing my best to help achieve them all”.  In his free time Jonn and his partner Blair enjoy walking their two dogs at River Park off leash or down 17th Ave SW, visits to local shops and restaurants, or escaping to the mountains for some hiking, skiing, and relaxation. Jonn looks forward to satisfying the unique needs and concerns that each of his client presents and the opportunity to develop long lasting meaningful relationships with them.

Follow Jonn on Facebook & Instagram! @jvbyyc

New: November 24th 1:01pm

Jonn VanBryce
Jonn VanBryce Calgary REALTORS® reviews

Real Estate Reviews

Your Real Estate Reviews, Testimonials & Comments are a valuable indicator of Jonn VanBryce performance and is a reflection of his/her reputation. Hearing how your experience was during your real estate transaction is the best way to ensure we are providing a service in line with our customers needs and expectations.

Our VERIFIED Calgary real estate reviews network is to provide authentic feedback from recent consumers which will help others when selecting a REALTOR®. By sharing your experiences, reviews you're helping other home buyers, sellers and home owners make better choices when hiring a local Calgary REALTOR®. From all of our feedback and lead forms to website integrations so that customers can filter reviews by the features that matter to them also helping them make better informed decisions. As a participant you should use caution and good judgment when assigning reviews & ratings and writing your comments. All Surveys are manually read and approved to maintain the integrity of data on this Exclusive Calgary real estate agents reviews network.


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Limited stock half price special !!!

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The family of Gail Brown, who was killed in a horrific crash on the A1307, have spoken of their devastation after her sudden death.

Gail, 56, of Lowry Close, Haverhill, died following a collision with a Ford Fiesta at about 12.15pm on Friday (22 December) on the eastbound carriageway at Bartlow.

In a statement her husband Ian, parents Pat and Michael, sister Lorraine and nephew David, said: “We are totally devastated at the loss of our beautiful Gail.

“Words can’t express how we feel at the moment, but we take immense comfort from all the messages of support we have received from the many, many people who knew and loved her.

Gail Brown died on December 22, 2017
Gail Brown died on December 22, 2017

“She will be sorely missed by so many people. We kindly ask for some time to grieve in private.”

The tribute was paid after the driver accused of causing her death by dangerous driving appeared in court on Boxing Day.

Sarah Hand, 50, of Aragon Road, Haverhill, appeared at Cambridge Magistrates' Court.

Hand did not indicate a plea in the hearing, which lasted less than ten minutes, and had to appear via video link as she was on crutches.

Hand has been remanded in custody and will make her next appearance, for a plea and trial preparation hearing, at Cambridge Crown Court on January 23.

You can keep up to date with all the latest news in and around Cambridge by downloading our free app.

It is available for the iPhone and iPad from Apple's App Store , or the Android version can be downloaded from Google Play.


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Motel Radio's Democratic Creation Process (INTERVIEW)

We got the chance to interview Ian and Winston of Motel Radio, an indie rock band from New Orleans. They shared insight about how they incorporate their audience into their music-making processes and how their unique band dynamic inspires their work.

Their viewpoints on creative value resonated beautifully with our motives to build this creative platform, and we hope their words inspire your artistic journeys as well.

Who are you?

Winston Triolo, 27

Roles: guitar, vocals, illustration, graphic design

Hobbies/passions: bouldering, running

Ian Wellman, 27

Roles: guitar, vocals

Hobbies/passions: photography, hiking, biking, pretty much anything outdoors

What genre would you consider Motel Radio to be under?

W: I would consider Motel Radio an indie rock band with folky, groovy, psychedelic influences (dad rock) since we have soo many dad fans.

How did your band get started? What's the significance of the name 'Motel Radio'?

W: We started writing music at the end of college in 2015 at LSU. The four of us had been friends throughout college and had become friends because of our musical interests. The band was first called 'Palmyra' but we later changed the name to 'Motel Radio' due to Palmyra already being taken as a band name. Motel Radio was a name that popped up while brainstorming and it had the imagery we were looking for. Most importantly, it wasn't already taken.

In the creation process of your most recent album, Siesta Del Sol, we assume you created more songs than were actually released on the album. What is the process of choosing songs to include on the album like? Do you have any specific qualities you look for to curate the album?

W: There were several songs that did not make the record which we plan on recording sometime in the future. Generally we go with what feels the best. A good way to test a song is playing it live and seeing how it feels/how the crowd feels about it.

What's your favorite song off of the album and/or what song are you most proud of?

W: Blue Love, Midnight

I: M.I.A.

I saw you on your tour with Summer Salt and loved your synchronized dance routine. It's very evident through your stage presence that you guys have a super strong and fun band dynamic. What do you think you each contribute to this dynamic?

W: We've been best friends for like 5 years. I try to be as real as possible. Andrew, our bassist, is the goofy guy. He's super lovable and happens to also be a CPA. Eric is the band dad/mom. He's responsible, and drives the van most of the time. He also probably wins the award for most stylish and well-groomed. Ian is our spiritual leader. He has plants and loves to talk about the universe, a very poetic and talented individual.

All together, we have very strong personalities, and are leaders/influencers in our own right. This can make it tough to come to a consensus on things, but I think it makes us stronger.

I: The whole music making process is very democratic. It's basically a majority rules mindset in the studio and just in general band life. I consider each person's opinion to hold equal weight. It's one of the things that I think makes our songs diverse, and helps keep us together. Everyone has to sacrifice.

Along with that, I noticed that you are all friends with the members of Summer Salt and Dante Elephante, the other opener on their tour. How has collaboration/working with other artists played a role in your band's journey/development?

W: It's always amazing to meet people our age who are doing the same things we are doing. It's like we are instantly friends because we have soo much in common. Dante and Summer Salt are so talented and have great music, so it's really easy to respect and admire them.

I: I always try to learn from the bands we play with.

They always seem to teach me something whether it's intentional or not.

The Summer Salt and Dante guys specifically are all so stupidly talented, and most are multi-instrumentalists. It was a lot of fun doing green room songwriters circles and hearing pieces from everyone's solo projects. And of course, all getting on stage together and going nuts.

What do you think is the most valuable part of being involved in a creative experience?

W: Self discovery, fulfillment, inspiring others to feel emotion

I: It feels like exercise.

Just as physical activity satiates your body, creative activity exercises your mind and soul. It shrinks the world down to something manageable.

:') Winston wasn't lying about Ian's spiritual, poetic talent.

Okay, now for some fun ones:

You're in a fashion show. What would your runway song be?

I: She Wolf - Shakira

W: Who Let the Dogs Out

Snails in jam or worms in peanut butter?

I: Like which would I prefer to eat? I guess I'd put them together and make a really weird PB&J.

W: Worms.

If you had a pet rock, what would you name them?

I: Zeus

W: Geodude

And lastly any other exciting projects coming up? We can't wait to hear more from y'all!

I: Working on a B side that didn't make the record, keep your eyes open :)

Interested or know someone who might be interested in getting featured in our community? Contact us here.

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About US:

From Camera to Canvas, sums up what we are about.

We believe photos are best Displayed, Shared and Enjoyed. So why leave them on your cameras or phones.
While this is handy and great to have access to them anywhere, anytime, wouln't it be better to create a stunning Photo Canvas, a fun Photo Mug or even a beautiful feature wall with our Photo Wallpaper.
We all have that special or amazing photo left on our camera. A beautiful sunset, a wedding photo or just clicking that button at that exact time.....wow.
So why don't you create a beautiful Canvas Print / Wallpaper etc . Have it on display 24/7 . where it can be enjoyed and admired for years to come.
Our products also make great gifts. Something unique that will show you care. Birthdays, Weddings, Communions, House Warming etc, the list is endless.
We use top quality materials to print your products. We have the best colour printers to reproduce your images
with fantastic colour reproduction. We will work with you on your project so you will be truely delighted with you purchase. That's our commitment to you.
Having worked as a graphic designer over the years I set up Camvas.ie in late 2015 to offer you a quality service. So if you need any help or advice, please contact us and we will be only to happy to assist you.
Thank you
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Canadian Biomass Magazine

News Biofuel Biofuels
Renewable Fuels Association congratulates US President-Elect Biden

November 10, 2020
By Renewable Fuels Association

The Renewable Fuels Association has congratulated President-Elect Joe Biden on his victory, as projected by the Associated Press and others. The following is a statement from RFA president and CEO Geoff Cooper:

“We look forward to working with the Biden administration in the years ahead to ensure a strong and growing market for low-carbon renewable fuels like ethanol. During the campaign, Joe Biden repeatedly stressed his support for ethanol and the Renewable Fuel Standard, which for 15 years has helped lower fuel costs for drivers, reduce dependence on foreign oil, boost the rural economy, and slash harmful emissions. President-Elect Biden understands that renewable fuels can play an instrumental role in our nation’s effort to decarbonize transportation fuels, and he also knows just how important a strong ethanol industry is to our nation’s farmers, rural communities, and consumers. We are committed to collaborating with the Biden administration on the many opportunities that lie ahead for renewable fuels.”


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Make An Enquiry

Tips to Make an Effective Healthcare Marketing Strategy

Tips to Make an Effective Healthcare Marketing Strategy

Before making the healthcare marketing strategy, it is necessary to understand what are the factors, which are required to target according to the current psychological state of the potential clients. Here are the factors, which can help you to work upon the healthcare marketing strategy.

  • Online habits of the patients.
  • Healthcare website design because the website design is a major aspect, which allures the online audiences.
  • Targeted healthcare SEO, which is most probably the local SEO.
  • Approaching the patients through social media marketing.
  • Video marketing, which is no longer a luxury now, and has become a necessary aspect for communicating with patients.
  • Patients reviews
  • Content marketing, which is one of the prominent sources to build authority in the market.

These are some of the factors, which are the part of healthcare marketing or can help you in making an ideal healthcare marketing strategy.

To make the strategy, you are required to work upon the goals of marketing. No doubt, the major goal is to attract the patients. But, you need to set the goals for different techniques, which will take you towards the prominent aim, i.e., to attract more clients to your healthcare firm or clinic.

1. Build Your Authority Online

It is required to understand first what exactly the authority is. Authority means when people trust you for your information as well as the services you offer. Next question to consider is how you can build this authority online. Simple answer – you need to add stuff online that could help the patients and give answers to their healthcare queries.

For building the authority, you need to add the relevant stuff for the audiences. You need to add tips for healthcare, first aid and a lot of health-related topics. Here, the question that you need to think about is where to add all this stuff.

Here are the mediums through which you can build your authority online.

This is a conventional way to build the authority online. Here the word “conventional” refers to a way which is being used for more than a decade, even at the time when there were not so much Google algorithm updates.

Blogging is an excellent way to solve the queries of the people via the posts. A number of internet users like to surf the internet for their health-related queries. Your blog posts may attract their attention, which can be further helpful for you also to get more clients.

When the individuals get the answers to their queries in your posts, they start trusting you, which further leads to trust building in the services you provide. There are many healthcare blogs active today on the web. The blog of 33 Charts, is one of the perfect examples in this regard.

You are required to do both on-site and off-site blogging to build a strong authority. It means that you should maintain a blog space on your website, as well as on some external sites. But, you need to update the blog regularly least once a week.

#Video Hosting Websites

The video hosting sites, among which YouTube is the prominent one, which is also considered as a social media site, is the perfect means to educate people in more effective ways. Videos are no more the luxuries of only the high-end marketers, it is a necessity for your healthcare marketing strategy. It is possible even for a common man today to upload a video. But, here, uploading any video is not sufficient, and you are required to add the professional quality videos. You can make videos with the help of experts, or by hiring some digital marketing agency.

With the help of video, you can give a live demonstration of a number of aspects, which is not possible in case of written text in blog posts. However, it is also a suggestable option to embed your videos in the blog posts, which will increase the value of your blogs several times more than usual. The two-way interaction is also possible now on YouTube by the means of live videos.

You can give some excellent tips related to healthcare. The YouTube channel of Dr. Oz is one of the perfect examples in this regard.

Apart from YouTube, you can upload the video to some other video hosting sites also, such as Dailymotion.

#Social Media Platforms

Social media platforms are another option to build authority and they are the perfect means for not just solving the queries of the people, but also to engage with them and to know their requirements. Engaging with the audiences is also helpful in giving you new ideas about your blog posts and videos. You can understand the requirements of the internet users and can pick the theme for your content accordingly.

In fact, some social media sites other than YouTube also provide the platform for uploading the videos. For example, you can also upload video or start a live video on Facebook. Instagram also provides you the option to add small videos on its usual platform and 10-minute videos on IGTV. Besides, you can also go live in Instagram stories.

On the social media sites, you need to create a business page or profile for maximum impact.

#Question and Answers

As already mentioned, answering the queries of the patients is a way to build the authority, so why not answer the questions directly. Quora is an ideal platform, where you can directly answer the questions as a part of your healthcare marketing strategy. You need to keep track of the new health-related questions being asked by the patients and answer them.

#Search Engine Ranking

Search engine ranking is a different aspect, but it can still be considered as an aspect for authority building. When your website gets the top ranking on certain keywords, it builds trust among the searchers. This is also considered as a perfect way for competing with the big brand.  The search engine ranking needs a vast description, and you will be able to read it the next point.

2. Target Healthcare SEO

According to reports, a huge number of people turn to the search engines when they have health queries. Your blog posts and videos do well for this purpose, but your blogs and videos need to appear in front of the right audience. And for that, it is necessary to rank your website on certain targeted keywords. This is the place, where the patients not just get their queries solved, but can also get their required services.

Besides, when the patients need healthcare services, the fact cannot be overlooked that the search engines are the major sources, which people use to look for them.

You can accomplish local SEO or organic SEO as per your requirement. Here are the things, which you can do.

#Local SEO

Local SEO is for targeting the local audiences, and for this purpose, the major thing you need to do is to add your location, working hours, etc. in the search engine directories. Google My Business and Bing Places are the two popular search engine directories, in which the details about your business can be included.

Whenever the healthcare services you deal in are searched on the search engines in your area, your clinic or hospital is displayed in the list. Moreover, your location is added to Google Maps and Bing Maps, which is not only displayed in the search results but also help the people in reaching at your place via GPS system through their smartphones.

#Organic SEO

Organic SEO is prominently based on keywords. In this, you need to target the keywords, which are used by the people for searching your services on the search engines. The keywords can be the combination of your services and location, and many other phrases, which is best suitable for your industry. Besides, the keywords are selected with the help of keyword research tools.

In addition to this, adding links to other sites, on-site optimization etc. are some other things, on which the work is required to be done.

To Sum Up

In the facts mentioned above, you get a concise idea about how to make the healthcare marketing strategy. Still, it may not be so easy for you to make a strategy. But, you have no need to worry in this regard in this era of tie-ups and team works. You can contact a healthcare marketing agency in order to make an ideal marketing strategy for your healthcare agency. We also have a team of experts to accomplish your marketing goals. Our experts have a vast knowledge of all the aspects of digital marketing. You can contact us and can get a perfect digital marketing strategy along with its implementation.

Make the right choice! Do you need a consultation? Call us now!

Stay Connected

Extend your social network with our help… Contact and Join with The Business Work


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Natural Killer Cells Could Fight Off ALL

August 29, 2014
Dave Levitan
Dave Levitan

A laboratory study found that natural killer cells could be multiplied from the blood of patients to fight off precursor B-lineage acute lymphoblastic leukemia.

A laboratory study found that CD56+ immune effector cells, or natural killer cells, could be multiplied from the blood of patients with precursor B-lineage acute lymphoblastic leukemia (pre-B ALL), and that those natural killer (NK) cells could be an effective tool in fighting off the malignancy without the risks associated with donor-based immunotherapy.

Patients with pre-B ALL typically have “a marked perturbation of normal hematopoiesis,” according to study authors led by Nora Heisterkamp, PhD, of the University of Southern California, meaning a deficiency in NK cells could contribute to the cancer’s progression. While donor cells could fight off the disease, there is a serious risk of graft-vs-host disease; the current study was designed to see if a patient’s own cells could be expanded to avoid that risk and help treat the ALL. The results were published online ahead of print on August 19 in Leukemia.

The group was able to expand CD56+ cells from both bone marrow and from peripheral blood samples, and from both newly diagnosed patients and from relapse samples as well. They then tested those cells for cytotoxic activity against ALL cells, and found such activity to be similar to normal NK cells derived from peripheral blood mononuclear cells.

And importantly, the CD56+ cells have specifically autologous activity. The cytotoxicity seen in the study could be improved further by the addition of interleukin-15; when cultured with IL-15 overnight the improvement was greatest.

The authors noted that if CD56+ lymphocytes could be expanded to sufficiently useful numbers then this treatment could be ready for use almost immediately. Though it is unclear at present exactly how many cells are needed, the authors were confident that enough cells could be generated from most patients with pre-B ALL.

“In this study, we used NK cells and ALL cells from the same pediatric patients,” Heisterkamp said in a press release. “We found that autologous natural killer cells will destroy the patient's leukemia cells.” Her co-lead investigator, Hisham Abdel-Azim, MD, of Children’s Hospital of Los Angeles, added that the results are very promising and that the treatment could particularly be used following chemotherapy as a way to ensure the eradication of minimal residual disease. “We anticipate additional pre-clinical testing, and then a clinical trial to evaluate the therapy in children with leukemia,” he said.


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