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CashUSA Installment Loans Evaluation April 2020

by Reda Ledoux (2020-08-17)

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I.B.I.S., Inc., a Sonata Software Company, understands that the achievement of your implementation depends upon permission to consultants similar to an arrangement of technology, your Dynamics application and your industry 4.0 the industrial internet of things by alasdair gilchrist's unique issue processes. fine thing, Microsoft Dynamics GP , a answer that we, at ERP Consulting LLC, a company that implements Dynamics GP in Pataskala Ohio, has a feature called Collections Management, a tool that will streamline deposit process and reports. 49 yr old Systems Administrator Rey from Guelph, really loves vehicles, What Is Industry 4.0? Everything You Need To Know … and music-drums. Enjoys travel and have been motivated after building a journey to Monarch Butterfly Biosphere Reserve. which is the best major in 4.0 industry

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text: TY - JOUR T1 - Tamoxifen Is a Potent Inhibitor of Cholesterol Esterification and Prevents the Formation of Foam Cells JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 1165 LP - 1173 DO - 10.1124/jpet.103.060426 VL - 308 IS - 3 AU - de Medina, Philippe AU - Payré, Bruno L. AU - Bernad, José AU - Bosser, Isabelle AU - Pipy, Bernard AU - Silvente-Poirot, Sandrine AU - Favre, Gilles AU - Faye, Jean-Charles AU - Poirot, Marc Y1 - 2004/03/01 UR - http://jpet.aspetjournals.org/content/308/3/1165.abstract N2 - Tamoxifen is a selective estrogen receptor modulator (SERM) used for the treatment and prevention of breast cancer. Tamoxifen has been reported to protect against the progression of coronary artery diseases in human and different atherosclerosis animal models by blocking the appearance of the atheromatous plaque. However, the molecular mechanism of this effect remains unknown. Acyl-CoA:cholesterol acyl transferase (ACAT) catalyzes the biosynthesis of cholesteryl esters, which are the major lipids found in the atheromatous plaque. In this paper we have tested whether ACAT might be inhibited by tamoxifen. We show, using molecular modeling, that tamoxifen displays three-dimensional structural homology with Sah 58-035 (3-[decyldimethylsilyl]-N-[2-(4-methylphenyl)-1-phenylethyl]-propanamide), a prototypical inhibitor of ACAT. We report that tamoxifen inhibits ACAT in a concentration-dependent manner on rat liver microsomal extract. We show that the presence on estrogen receptor ligands of a backbone isosteric to the diphenyl ethane backbone of Sah 58-035 constitutes a pharmacophore for ACAT inhibition. More importantly, tamoxifen was able to inhibit ACAT on intact macrophages stimulated with acetylated low-density lipoproteins and blocked the formation of foam cells, a step that precedes the formation of the atheromatous plaque. This work constitutes the first evidence that tamoxifen is an inhibitor of ACAT and foam cell formation at therapeutic doses and that this may account for its atheroprotective action. The American Society for Pharmacology and Experimental Therapeutics ER -


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Dermatology Marketing: How to Grow Your Practice Online

Dermatology, and thus dermatology marketing, is growing rapidly. Not only has awareness of and need for skin cancer treatments increased, cosmetic treatments like Botox and anti-aging procedures are also on the rise. Dermatologists are the life-saving heroes of skin cancer patients and the fairy godmothers of aging. They provide both clinical treatment and cosmetic services to those who need it.

With an increase in demand, dermatologists need to push more and stand out from the crowd to make sure all those people searching for their services can find them with ease.

And what’s the best way to do that? Marketing.

It isn’t easy to create and carry out an entire dermatology marketing plan from scratch. It takes expertise, experience, and most of all, time. Now, I know time isn’t something you have when you’re juggling running a clinic, managing staff, and getting better at your practice! But it’s absolutely essential that you know the basics of marketing your dermatology practice if you’re going to keep running it.

So, to make things easier, we’ve created a dermatology marketing guide that will help you reach new patients. We’ll be listing what you need, some strategies, and some tips at the end.

Now, so we don’t waste any time:

Dermatology Marketing

dermatology marketing

More and more healthcare practices are turning to digital marketing to keep up with the new world of business.

Even if healthcare is an essential business, people are now aware of the choices and options they have. It’s so easy to go online and search “dermatology clinics near me.” If the patient doesn’t find you online, you’re immediately off the table.

This makes digital marketing an essential for dermatology practices. You need to show up online and look good!

Dermatology Marketing Necessities

Before starting a marketing campaign online, there are a few things you’re going to have to set up.

We’re loving Apostrophe’s clean, minimal, and easy to navigate website. Something as simple and attractive as this can already impress your website visitors.

The first thing you’re going to need is a website. Your website is your front desk, online. This is where potential patients will go when they want to learn more about your clinic or if they’re considering your practice.

It’s also where prospective clients will form their first impressions of your clinic. With that said, your website needs to be dressed to impress.

It should exhibit your skills and credibility, your services and the conditions you treat, your staff and location, and an easy way to get in touch. You can also provide clients an information section or an about page where they can read more about you and your clinic, your vision, mission, core values, ethics, etc. Make sure to include lots of testimonials!

Aside from design, how your website functions is vital. User experience is a big deal for website visitors when it comes to deciding whether or not they should contact your clinic. Users should be able to easily navigate your website and find the information they need. It should be optimized for both mobile and desktop users.

One great way to make it easy for patients to reach out is a chat bot, where they can ask questions regarding their suitability as patients and make contact with a real person without picking up the phone.

If you really want to get into the 21st century, have a booking page where clients can fill out intake forms and schedule appointments with you online. This will definitely give you an edge over competitors who insist on their patients going the old school route of calling to book an appointment and spending the first 15 minutes of that appointment filling out forms.

You can hire a dermatology marketing agency like us to create a website that perfectly represents your brand. Give us a call or send us a message and we can make a kickass website like the one below.

dermatology marketing

Pure Dermatology wanted to stand out with their branding and digital presence. They were looking to expand their medical practice by creating a brand identity that is cohesive and consistent across all digital and print materials.

So we created a website that focused on close-up shots of the skin with images set in a cool blue or gray background color palette. Furthermore, we kept the images focused on the portrait, selecting photos with fewer background elements to convey that fresh, modern, carefree feel that is Pure Dermatology. Their website features lots of reviews, clear call to actions, and all the information you could ever need on their services.

The best thing about PPC (Pay Per Click) ads is that they only target users who are actively searching for your services, and you only pay every time someone clicks on your ad. It’s efficient and cost effective in that sense.

Another bonus is the fact that you can track and analyze your campaigns. There is analytic software you can use to track your ads to improve, optimize, and create more effective ad campaigns.

The trouble is, mastering Google Ads is not a pain-free process. It takes a lot of time, testing, and retesting to figure out an audience, ad, and keyword set that are going to work for you, and you will lose money in the meantime. We don’t recommend venturing into the world of PPC management without an expert to help you out.

Google My Business local listings

More and more people are turning to Google to search for local products and services they need. It’s an increasing trend for users to search “near me” queries for their convenience.

“Near me” or “close by” type searches grew by more than 900% over two years.”
Chat Meter

Google My Business is a free platform that helps local businesses be seen online. Google My Business lets you manage how you want your business to appear on Google Search and Google Maps.

Your listing should feature important, up-to-date, and accurate information about your business. When you create your listing for your dermatology clinic, you need to specify your clinic name, location, hours, and contact number. This is crucial information that your potential clients will want to know.

Aside from basic, yet important, information, Google My Business allows you to reply to customer reviews, add photos, accept bookings, see your analytics, and share any updates about your clinic. Once you have a listing, make sure you take advantage of the many features, and above all, request reviews! You will be favored by search engines and gain more interest from potential patients for your efforts.

Having your clinic listed with Google will give you a chance to reach locals who are searching for a dermatology clinic near them.

Social Media Pages

We’re loving DermUtopia’s Instagram page. They’re super engaging and they post photos that could benefit their clients.

Social media has evolved from being platforms that connect people to something more. Most people use them as a kind of background/credibility check for businesses. Users will check a clinic’s social media page to get a better idea of what the practice is like and whether or not they want to become a patient. Now, social media accounts are a must for all dermatology practices.

If your social media page is unkempt, people will assume your clinic isn’t legit. An active business on social media shows authority, builds trust, and keeps you top of mind with your patients.

Another important thing to keep in mind when it comes to social media is consistency. Your tone of voice, your overall aesthetic, and how regularly you post should all be consistent. It’s a lot of work, but absolutely crucial to a successful social media strategy. If you decide this is the direction you want to go but you don’t want to personally be responsible for the work, use a digital marketing agency to ease your load. That way you can focus on your practice and leave the dermatology marketing to the experts.

Dermatology Marketing Strategies

dermatology marketing strategies

Be clear on your services and target audience

This is going to sound like common sense, but you’d be surprised how many dermatologists don’t do this: list all of your services on your website, social media, business listings, and any other place your clinic info appears. If you’re going to grow your dermatology business, you really have to be clear on the services you offer. After all, it’s the services your patients are after. They might not know you can take care of their condition if you don’t list it in your services.

Speaking of your patients, make sure you are making an effort to get to know your audience. How old are most of your patients? Are they mostly there for cosmetic services, or medical? Why did they choose you, and can you get them to recommend their friends or leave a review? You must know who your market is and how to maximize the impact of each patient.

Apostrophe uses diverse models to send a message that they serve many demographics, and dermatology is not just for women.

Patient experience first

We all know nothing can beat how effective word of mouth is when it comes to marketing and advertising. The majority of people have bought something or acquired services through a friend’s recommendation.

The best way to get the word of mouth marketing campaign rolling is by concentrating on your patient experience with your clinic. Each person should leave your clinic feeling like the money they paid was worth it.

Positive patient experience can be achieved by making sure their interaction with you, from the first moment they discover your clinic until after their appointment, is pleasant and comfortable.

Respect your client’s time and make sure the booking process is smooth. Your staff needs to be welcoming, approachable, kind, and gentle. You can also track the satisfaction of your patients by doing patient surveys. Ask for their feedback so they know you care, plus you get to improve your services.

You can also ask them if they could leave you a review online. This way, those who see your dermatology clinic online can see the experience of your previous patients. These reviews are as powerful as word of mouth, so don’t forget to ask your patients for one.

SEO strategy

All businesses want to be on the first page of Google’s search results, and an awesome SEO strategy is key. There are countless benefits to having a kickass SEO strategy, like:

  • Higher search results ranking
  • Increased website traffic
  • Increased brand awareness
  • Credibility
  • Generate leads and increase conversion rates

The only way to acquire those benefits is by optimizing your dermatology website.

We can’t go through all the ways to optimize your website for search engines here, but this article on Tips to Improve Your Website’s SEO Ranking should give you lots of action items!

Content marketing

One surefire way to improve your SEO is by blogging. Include a blog on your website and make sure to update it regularly to increase your chances of getting a higher SEO rank. Blogs are great for driving traffic and attracting potential patients to your website.

There are many topics you can explore, such as product reviews, how-tos, skincare tips for different skin types, etc. Just make sure it’s valuable to potential clients and includes the keywords you want to rank for. Google will see the new content going up on your site and deem you relevant, up-to-date and knowledgeable. Make sure you share your blog posts on your social media page, emails, etc.

SkinTour is a top-rated dermatology blog, and we can see why. She posts content consistently and keeps providing value to her readers.

Blog posts don’t have to be super formal or even long. Make them conversational, easy to read, interesting, and informative. These pieces of content have to provide value to get more users to read them.

If you’re too busy to manage a blog and consistently produce content, you can hire freelance writers or work with a digital marketing agency that can write and manage for you.

Dermatology Marketing Tips

Promos, Specials, & Giveaways

Promos, giveaways, and specials are great for engagement, brand awareness, and tempting potential patients to buy your products or acquire your dermatology services.

These promos and specials will leave people with a sense of FOMO (fear of missing out.) They will want to grab the opportunity of a discount or promo code while it lasts.

dermatology technique - promotions
Dr. Wang Herbal Skincare is a dermatologist with his own products. The brand uses promotions, specials, and giveaways to entice users to engage with his brand and buy his products.

Giveaways are a great way to gain attention for your brand. If your contest requires sharing a post or tagging people, more and more people will know your brand and join the hype.

You don’t have to sell products to do specials or giveaways. Offer a one-time cosmetic treatment for free or 50% off – it just has to be enticing enough for social media users to be willing to share it or tag a friend. It’s a great way to spread the word about your services, gain followers, and get your social media engagement up! It’s usually a cheap dermatology marketing campaign with great payoff!

Online Booking & Payment

We love how Advanced Dermatology and Cosmetic Surgery included an online booking and payment option for their patients. It’s convenient, time-saving, and it gives patients a positive experience because it creates smoother transactions.

We live in a time where there is software available that can ensure the safety and privacy of patients who want to book an appointment online and make their payment.

ZocDoc is a trusted software that allows patients to book the appointment they want any time, any day.

Video Marketing

LA Beauty Skin Care Center Does a great job of posting videos on their Instagram profile. They post anything from procedures to before and after videos and fun shots of their team.

Videos have been a trend on social media for quite some time now, and it won’t be going anywhere anytime soon.
You can incorporate video marketing by posting video ads or just short clips on social media.

Videos are great for holding peoples’ attention. You can shoot a video that shows your procedures, a before and after, a tour of your clinic, you giving advice, your staff, a day in the life of a dermatologist, skincare tips and secrets, and many more.

There’s no need for fancy equipment. We’re lucky to be living in a world with smartphones that shoot high-quality photos and videos.
Trust us when we say that video marketing is a worthy investment. Your dermatology clinic will attract attention and generate brand awareness, increase engagement and get higher conversions.

Social Proof

dermatology marketing technique - social proof
Pure Dermatology Denver includes all their certifications on their website to communicate their trustworthiness.

Credibility and trust are extremely important when it comes to dealing with anything related to the medical industry.

People want to be sure they’re in good hands, but how can you prove that?

The answer? Social proof!

Make sure ample reviews and testimonials appear on both your website and all business listings and profiles. We recommend a minimum of three on each platform you appear on, but more is always better!

However, there are other ways you can provide users with social proof:

  • Write blog posts on any awards you receive
  • Share news publications or features
  • Use the logos of certifications you have on your website
  • Repost images shared by happy patients
  • Post glowing reviews on social media

Anything that signals to potential patients that you are trustworthy and provide good value is great social proof!

There are various tips, tricks, and strategies you can use to improve your dermatology marketing campaign. You have some good ideas here, now you just need to execute them!

Digital marketing requires you to learn a lot, from editing websites and creating ads to writing content, SEO, SEM, and much more. It can get really overwhelming when you’re already running a dermatology practice.

There’s no shame in asking for help! You can always partner up with experts like us to turn your ideas into a reality. We’re your growth partners, let us help your practice reach greater heights with our dermatology marketing services!


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Drawing the line

Where does a father draw the line between protecting his child from abuse and trying to heal his mentally ill, narcissistic / megalomaniac (assessed by a doctor of psychology) wife after years of struggle? To what extend should he go in confronting his wife to put an end to the abuse she is subjecting her own child to? What can he do against the tyranny of a government that not only separated him from his baby and put him through immeasurable humiliation and suffering, but also helped his mentally ill wife to kidnap his daughter when this government is also the government of the country he has to immigrate to to be with his baby?

I ask you, especially you Canadians, what would you have done if a government scammed you out of your good life with lies, took everything you have, enslaved you, tortured you, dehumanized you for years; forced you to making a choice between starvation and homelessness, and being with your infant child; most importantly, helped kidnapping of your child and made it impossible for you to get her back with illegal, inhumane games? What would you do to that government if you were capable of responding in kind? What would you do if you have tried every legal option under the sun and nothing worked? Would you rather be a good mother or father and force that government to return your child by using all the means available to you or would you rather be a good human being and abandon your child by either ending your own life as some do or by running away?

I chose to fight until I exhausted every possible option under the sun to get back to my daughter through legal channels. I’ve spent over 5 years to set things straight yet haven’t been able to see my daughter for 3 and a half years now after she was kidnapped by her mother and the Canadian Government. I chose to be a good man over being a good father and did not retaliate in kind, in the way that this racist, sexist, rapist, child abusing, immigrant exploiting, lawless, monstrous government deserves.

Give me an honest answer Canada, what would you do if a foreign, rogue government, let’s say Saudi Arabia, has done all that to you and to your child? Have I made the right choice?

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The Mallet Tour

I know this podcast isn’t anything revolutionary. I have my returning listeners and am slowly working to expand my audience along with the content I offer each week. One interesting trend I’ve noticed with each episode is a growing number of people requesting a particular guest on an upcoming podcast. Sure, compared to most of my guests, 3 or 4 people asking for a featured interview isn’t too monumental, but there has been a noticeable trend of people asking for “Phoenix”. It’s time I give into the demands of the listeners. Co-host of the Post Game Report, Marc Washington is my guest this week. You might know him as Phoenix410. If you don’t know him, you’re in for a treat and if you do know him, then prepare for a side of “The Mallet” that you have never heard before. And will likely never hear again.

Just Talking – Episode 21: The Mallet Tour

I’m not particularly fond of the term “Internet Famous” but if ever there were a person to qualify within the few communities I participate in, Marc Washington is Internet Famous. Also known as Phoenix410, Marc is a co-host of the Post Game Report (of which I also co-host) and has generated an enthusiastic following with his personality. This episode features a rare look at the Man behind the Mallet as we discuss the Talking About Games community, his unique approach to podcasting, Beyonce and much more. Enjoy.

Run Time – 1:20:10

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Sigmund Freud

I told my latest guest on Just Talking about this crazy plan I had for our recording. The plan was to see how long we could go without referencing the fact that we have known each other since we were 13. You might laugh, but it’s much easier said than done. I’m sure you can tell when I bring on a guest that I’ve talked to before, there’s a level of comfort that makes a huge difference in how I approach the recording. Maybe it’s just because we’ve known each other for so long, but I enjoy these types of conversations just as much as the ones with people I have only met mere seconds before the recording starts. I like to mix it up a bit. I suppose this means I’m due for a total stranger soon. Anyway, my best friend Nate came on the podcast to talk about Clinical Psychology, Blacksburg, weddings, and other fun stories from our collective past. Good times indeed.

Just Talking – Episode 28: Sigmund Freud

I finally convinced my good friend Nate Gillard to come on my podcast. He’s a grad student at North Texas and is on his way to becoming a pretty big deal. We spend a good portion of our time talking about his program, his work and his potential future. Given our history we also spend some time retelling some stories from the glory days in High School and our time living together at Virginia Tech. We do our best to either keep the inside jokes to a minimum or explain where the sudden laughter is coming from. As it stands, this podcast was also a great opportunity to catch up with Nate since I haven’t talked to him in a while. This is a conversation at its most casual form, I hope you enjoy it.

Run Time – 1:01:33

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Full Face Safety Shields

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Six Pack Dispensers of K9 Honey (12oz)

K9 Honey

Regular price $4.00

You are getting a counter top dispenser stand custom made for K9 Honey 12oz jars. This counter top display accommodates (6) 12-oz jars.

9 regions - 9 pollens

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Pain in the Chest vs. Pain in the Wallet

by | Cash Flow, Weekly Column | 2 comments

man-having-chest-pain.jpgIt wasn’t a heart attack.

A few nights ago, I woke up about 3:00 a.m. because of pain in my chest. It hurt to breathe. Sitting up or shifting my position didn’t seem to help. Twisting from side to side made the pain worse. I couldn’t isolate the pain to a specific set of muscles, which seemed like a bad sign. I didn’t have pain or numbness in my arms, which seemed like a good sign.

I debated. Was I having a heart attack, or wasn’t I? I tried to convince myself that it was muscle soreness from a change in my weight lifting routine two days earlier. But why would that have taken so long to make itself felt? Maybe it was stupid not to go to the emergency room to make sure. But an ER visit would easily cost $1000 or more. Should I, or shouldn’t I?

Finally, after worrying for a while, I did what any sensible 21st-century guy in my position would do. I got out of bed and went to look up “chest pain” and “heart attack symptoms” on the Internet.

The more I read, the more it seemed that my symptoms were not indicators of a heart attack. Eventually, I read that, if chest pain was aggravated by twisting from side to side, it was almost certainly muscle pain rather than a heart attack. Reassured, I went back to bed and managed to get a few more hours of sleep.

Over the next couple of days, the pain decreased. The next time I went to work out, I could clearly feel that it was indeed muscle soreness. In this case, my decision not to go to the emergency room had turned out to be the correct

As I’ve thought about this incident since, however, I’ve realized something that surprised me. One of the most important factors in my decision not to get my chest pain checked out was the cost. As I lay in bed wondering whether I could be having a heart attack, I kept thinking, “But it would cost over $1000 to go to the ER.”

Unlike too many other people, I have health insurance. It does have a high deductible, so the first $2500 of whatever a trip to the hospital might have cost would have come out of my pocket. Again unlike many people, I could afford to pay that cost. And still, even in my fortunate circumstances, cost was one of the reasons I was reluctant to get medical help for a potentially life-threatening condition.

Thinking about this gives me a glimpse into the level of stress and fear that people who can’t afford health insurance must live with on a daily basis. People like the 20-something son of one of my friends, who is struggling to get a new business started. He’s a hard worker, and someday he’s probably going to be rich, but right now he’s just barely making it and doesn’t have the money for health insurance.

He just had to have emergency surgery. The procedure was relatively minor, but it still left him insurance-man.jpgwith some $15,000 in medical bills. He’s negotiating with the hospital to see if he can get the bill reduced and make arrangements to pay it. In the meantime, his parents have decided they can afford to pay approximately $130 a month to get an individual health insurance policy for their son.

Parents frequently help kids get started in the adult world by buying them cars or helping them out in other ways. It may make a lot of sense to consider health insurance as one of those “other ways.”

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Kalypso Awarded Oracle Titan Award, First Global Award for Applications Partner of the Year

October 13, 2009

Oracle presents Kalypso with two awards honoring the firm's excellence in delivering innovative, real-world solutions: Oracle North American Titan Award and Applications Partner of the Year

SAN FRANCISCO, California - October 13, 2009 - Kalypso, the world's premier innovation consulting firm, announced today that it has received the first Oracle® PartnerNetwork Global Award for Applications Partner of the Year. In addition to this honor, Kalypso also received the Oracle 2009 North American Titan Award for Specialty Applications Solution. The prestigious Oracle awards were presented on Sunday, October 11, at the Oracle OpenWorld Welcome Reception and North American Titan Awards ceremonies in San Francisco.

The Oracle PartnerNetwork Global Awards program, which is in its inaugural year, recognizes partner solution innovations worldwide that utilize Oracle products to solve real-world business challenges. The program highlights partner excellence in several categories, including Technology, Applications, Industry, Accelerate, and Midsize. Kalypso's solution-an Oracle Agile Product Lifecycle Management (PLM) implementation for a global provider of commercial cleaning and hygiene solutions JohnsonDiversey Inc.-was chosen from more than 250 nominations that were reviewed by a global panel of executives at research firm International Data Corporation. Kalypso's solution earned the panel's highest score to receive the Applications Partner of the Year Award.

"Kalypso is providing our joint clients with creative PLM solutions that are accelerating these companies' innovation and growth through enhanced collaboration," said Judson Althoff, senior vice president, worldwide alliances and channels, Oracle. "Behind this success is Kalypso's extensive knowledge of Oracle Agile PLM, deep industry experience, and a focus on business process design supported by technology that provides the marketplace with a true enterprise PLM perspective."

Additionally, Kalypso's solution for JohnsonDiversey was selected from among 144 submissions to receive the North America Oracle Titan Award for Specialty Applications Solution. The Titan awards are given by Oracle to its leading partners for excellence in a number of categories, including sales, marketing, and solution development.

"Kalypso is tremendously honored to receive both the first annual Oracle Global Award for Applications Partner of the Year and the Oracle Titan Award for Specialty Applications Solution," said George Young, Kalypso founding partner and Oracle alliance leader. "Oracle's recognition points to the power of Oracle Agile PLM software and Kalypso's proven implementation methodology to help our clients deliver on the promise of innovation."

Kalypso worked with JohnsonDiversey to globally consolidate its product development processes and provide visibility into development work across North America and Europe. Kalypso also assisted the company in designing and deploying a unique global design implementation process as part of its PLM initiative. By simplifying the maintenance of products, working capital and inventory through new efficiencies in product development, commercialization, and data quality and reporting, the PLM program has resulted in better decision-making capabilities and significant cost reductions for the organization.

About Oracle PartnerNetwork
Oracle PartnerNetwork is a global business network of more than 21,000 companies who deliver innovative software solutions based on Oracle software. Through access to Oracle's premier products, education, technical services, marketing and sales support, the Oracle PartnerNetwork program provides partners with the resources they need to be successful in today's global economy. Oracle partners are able to offer their customers leading-edge solutions backed by Oracle's position as the world's largest business software company. Partners who are able to demonstrate superior product knowledge, technical expertise and a commitment to doing business with Oracle qualify for the Certified Partner levels. http://oraclepartnernetwork.oracle.com

About Kalypso
Kalypso is the world's premier innovation consulting firm, helping clients improve profitability by delivering on the promise of innovation. Kalypso offers clients full service capabilities including Business and Innovation Strategy, Front End of Innovation, Portfolio and Pipeline Management, Development and New Product Introduction, Value Management, PLM Technology, Leadership and Learning, and Intellectual Property Services. For more information, visit http://www.kalypso.com.

Oracle is a registered trademark of Oracle Corporation and/or its affiliates.


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Cupcake Camp Sydney 2010

It was great fun last year so we’re doing it again.  Bake and share cupcakes and raise money to support the RSPCA and Doggie Rescue.

The video from last year is up on YouTube to inspire you.

Follow us on Twitter: @cccsyd

See what’s happening at #cccsyd

When: TBD but we’re looking at either Friday 20th or 27th August 2010 (5.30 pm – 7.30 pm)

Where: CBS Interactive Sydney

Why? Why not?

Author: Kate Carruthers

Sometimes I feel like being a revolutionary cat.


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Windows x64 | File size: 1.54 GB

ON1 Photo RAW version 2021 is THE professional-grade photo organizer, raw processor, layered editor, and effects app.

It works where you do; at the center of your workflow or as a plug-in to Adobe Photoshop, Lightroom, Elements, Affinity Photo, Corel Paintshop Pro, and Capture One (coming soon).

ON1 Photo RAW 2021 provides the primary photo editing needs for every photographer regardless of what they shoot – without having to bounce between multiple pieces of software. Get the professional photo editing tools you need for the professional results you need while keeping your workflow efficient, powerful, and simple.

At its core, ON1 Photo RAW includes a state-of-the-art image processing ee. Optimized for today’s super-megapixel cameras and high-performance computer graphics systems, Photo RAW is the world’s fastest, most flexible, and easiest-to-use photo editor on the market.

Creators want to create and not spend all of their learning how to use editing tools. Photo RAW is like having Lightroom & Photoshop under one roof. It comes with the tools you need for compositing, hundreds of the hottest presets and filters built-in, and world-class masking tools to make your life easy.

ON1 Photo RAW gives you an open system for complete control over your storage, organization, editing, and method of purchase. No long importing, easy organization, unlimited ways to dial in your style, and ON1 will also never be a subscription-only model.

ON1 Portrait AI is the perfect fit for almost any workflow. Get amazing retouching results in seconds when using ON1 Portrait AI as a plug-in for:

– Adobe Photoshop

– Adobe Lightroom Classic

– Adobe Photoshop Elements

– Affinity Photo

– Capture One (coming soon)

– Apple Photos

– Corel Paintshop Pro

– Quickly Add Clouds to Your Dull Skies

– Retouch an Entire Portrait Shoot Automatically

– Create Stunning Sunsets in Seconds

– View Your Photos in All of Their Beauty

– Refresh Smiles in a Few Simple Clicks

– Selectively Edit Like Never Before Using Color Selection

– A Better Way to Erase Away Unwanted Distractions

– Find Your Duplicate Photos in Seconds

– Easily Change Colors of Objects in Your Photos

– Quickly Find All Photos from Your Favorite Location

– Make the Eyes Pop in Seconds

– The Best Photoshop Plugin for Editing Portraits

– Presenting Photos for Your Clients

Flawless retouching is just a click away with the new Portrait AI tab inside of Edit. It uses machine learning to find every face in your photo and make them look great, automatically. It analyzes each face and adds just the right amount of retouching to the skin, eyes, and mouth, giving you professional results in no at all.

The New Smart Organize mode in Browse lets you take control over your cluttered photo archive. Not only can it find duplicates, but it can find and group photos that have similar appearance, location or . It can help you cull your library to find just the best photos in a series.

A new modern approach to removing distractions like dust spots, power-lines and unwanted people from your photos. The Spot Healing Brush is not only faster than current tools, it maintains full non-destructive adjustments for each spot you remove.

Brushing has taken a quantum-leap in control and creativity. Now you can choose from a variety of custom brush shapes or even import your own.

Now you can extend your workflow in Affinity Photo and Corel PaintShop Pro by access Develop, Effects, and Portrait right inside the apps you use. Capture One support coming soon!

Need to quickly show a client their photos? With the Quick Slideshow you are only a click away from a full-screen slideshow complete with user adjustable delay and an elegant dissolve transition.

Now you can automatically apply a preset to any new photos from a specific camera. If you always find yourself making the same adjustments, just make a preset and apply it automatically to photos from that camera. This is super handy if you have created a custom camera profile or if you have converted a camera to infrared.

Everyone knows how powerful the gradient mask tool is. You can quickly create straight, reflected or round radiant masks that are re-editable and blendable with brush masks. Now you can combine the color-sensitive power we created for the Perfect Brush with the gradient masks. When enabled, it detects the color under the gradient and applies the mask to only that adjustable color range. It makes it a breeze to mask areas like skies while maintaining things like buildings or trees that go into the sky.

Save by batch processing your HDR brackets or panoramas. Simply organize your brackets into sub-folders, then let Browse build your new HDR and panos for you. This is a life-saver for real estate shooters.

We have taken a measured approach to updating the user interface. Based on user feedback we have improved common controls like sliders to have more precision and a longer area for labels so we can be more descriptive. We have also made sure that Layers and the Edit module tabs don’t scroll out of view on a small display or when you have a large stack of filters.

We have brought back color fill layers to the Layers pane. They are a great way to set a background color for a composite layout. They are also handy when used with the new custom brush shapes for painting in objects like grass, trees, and clouds.

Easily change the color of an object to any new color. It’s perfect for tweaking or totally chag the color of eyes, flowers, buildings, and apparel.

– Windows 10 (current maintenance releases, 64-bit only)

– Processor: Intel Core i5, Xeon, or better

– RAM: 16+ GB

– Disk: 1.5 GB for installation, SSD

– Display: OpenGL 4.2-compatible video card with 2GB dedicated video RAM, 1920×1080 resolution (at 100% scale factor)

– Photoshop CC 2020

– Photoshop Elements 2020

– Photoshop Lightroom Classic CC 2020

– Affinity Photo

– Corel PaintShop Pro

– English, German, Spanish, French, Japanese, Korean, Simplified Chinese, Russian, Portuguese, Italian, Dutch

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King's College London

Research portal

Common and Distinctive Functions of the Hippo Effectors Taz and Yap in Skeletal Muscle Stem Cell Function

Research output: Contribution to journalArticle

Congshan Sun, Vanessa De Mello, Abdalla Mohamed, Huascar P. Ortuste Quiroga, Amaya Garcia-Munoz, Abdullah Al Bloshi, Annie M. Tremblay, Alexander von Kriegsheim, Elaina Collie-Duguid, Neil Vargesson, David Matallanas, Henning Wackerhage, Peter S. Zammit

Original languageEnglish
JournalStem cells (Dayton, Ohio)
Early online date27 Jun 2017
Accepted/In press7 Jan 2017
E-pub ahead of print27 Jun 2017

King's Authors

Hippo pathway downstream effectors Yap and Taz play key roles in cell proliferation and regeneration, regulating gene expression especially via Tead transcription factors. To investigate their role in skeletal muscle stem cells, we analyzed Taz in vivo and ex vivo in comparison with Yap. Small interfering RNA knockdown or retroviral-mediated expression of wild-type human or constitutively active TAZ mutants in satellite cells showed that TAZ promoted proliferation, a function shared with YAP. However, at later stages of myogenesis, TAZ also enhanced myogenic differentiation of myoblasts, whereas YAP inhibits such differentiation. Functionally, while muscle growth was mildly affected in Taz (gene Wwtr1-/-) knockout (KO) mice, there were no overt effects on regeneration. Conversely, conditional KO of Yap in satellite cells of Pax7Cre-ERT2/+: Yapfl°x/fl°x: Rosa26Lacz mice produced a marked regeneration deficit. To identify potential mechanisms, microarray analysis showed many common TAZ/YAP target genes, but TAZ also regulates some genes independently of YAP, including myogenic genes such as Pax7, Myf5, and Myod1 (ArrayExpress-E-MTAB-5395). Proteomic analysis revealed many novel binding partners of TAZ/YAP in myogenic cells, but TAZ also interacts with proteins distinct from YAP that are often involved in myogenesis and aspects of cytoskeleton organization (ProteomeXchange-PXD005751). Neither TAZ nor YAP bind members of the Wnt destruction complex but both regulated expression of Wnt and Wnt-cross talking genes with known roles in myogenesis. Finally, TAZ operates through Tead4 to enhance myogenic differentiation. In summary, Taz and Yap have overlapping functions in promoting myoblast proliferation but Taz then switches to enhance myogenic differentiation.

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Building a Casual Wardrobe0

In the many years that KC’s Boutique has been open, we’ve learned a formula that works well with any casual wardrobe.

When you purchase a new pair of bottoms, invest in or make sure you have 5 tops that match. By following this tip, you will be sure to always have an outfit that comes together in a snap!

This formula works especially well when you are purchasing a bottom in a unique fashion colour because you will always be able to pull together an outfit without worrying about finding matching tops at a later date.

This basic wardrobe principle keeps the stress out of dressing!

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Kulmeet Sandhu

Kulmeet Sandhu

Clinical Associate Professor of Surgery (Clinician Educotor);Surgery Clerkship Director
1510 San Pablo St. Health Sciences Campus Los Angeles

Surgical trends in the management of acute cholecystitis during pregnancy Surg Endosc. 2020 Oct 06. . View in PubMed

Educational benefits of an acute care surgery rotation during the medical student surgical clerkship Am J Surg. 2020 Oct; 220(4):858-860. . View in PubMed

Safety and efficacy of robotic-assisted groin hernia repair J Robot Surg. 2020 Aug 10. . View in PubMed

Effects of smoking on bariatric surgery postoperative weight loss and patient satisfaction Surg Endosc. 2020 Jul 22. . View in PubMed

Routine esophageal manometry is not useful in patients with normal videoesophagram Surg Endosc. 2019 05; 33(5):1650-1653. . View in PubMed

Regression of intestinal metaplasia following magnetic sphincter augmentation device placement Surg Endosc. 2019 02; 33(2):576-579. . View in PubMed

Gastric cancer in the young: An advanced disease with poor prognostic features J Surg Oncol. 2017 Mar; 115(4):371-375. . View in PubMed

Efficacy of magnetic sphincter augmentation in patients with large hiatal hernias Surg Endosc. 2017 05; 31(5):2096-2102. . View in PubMed

Post-Nissen Dysphagia and Bloating Syndrome: Outcomes After Conversion to Toupet Fundoplication J Gastrointest Surg. 2017 03; 21(3):441-445. . View in PubMed

Charges, outcomes, and complications: a comparison of magnetic sphincter augmentation versus laparoscopic Nissen fundoplication for the treatment of GERD Surg Endosc. 2016 08; 30(8):3225-30. . View in PubMed

Primary sleeve gastrectomy compared to sleeve gastrectomy as revisional surgery: weight loss and complications at intermediate follow-up J Gastrointest Surg. 2014 Oct; 18(10):1737-43. . View in PubMed

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Stephen F. Sener

Stephen F. Sener

Clinical Professor of Surgery (Part-Time)
2051 Marengo St. Health Sciences Campus Los Angeles

Factors affecting the incidence of chronic pain following breast cancer surgery: Preoperative history, anesthetic management, and surgical technique J Surg Oncol. 2020 Aug 19. . View in PubMed

COVID-19 corner J Surg Oncol. 2020 Aug; 122(2):113-114. . View in PubMed

Factors associated with MRI detection of occult lesions in newly diagnosed breast cancers J Surg Oncol. 2020 Mar; 121(4):589-598. . View in PubMed

Advances in axillary surgery for breast cancer 2019 J Surg Oncol. 2020 Jan; 121(1):20-24. . View in PubMed

MRI does not predict pathologic complete response after neoadjuvant chemotherapy for breast cancer J Surg Oncol. 2019 Nov; 120(6):903-910. . View in PubMed

Clinical findings and outcomes of MRI staging of breast cancer in a diverse population Breast Cancer Res Treat. 2019 Apr; 174(2):315-324. . View in PubMed

Factors Leading to Decreased Rates of Immediate Postmastectomy Reconstruction J Surg Res. 2019 06; 238:207-217. . View in PubMed

Comparison of cone-beam computed tomography and panoramic radiography for mandibular morphometry Folia Morphol (Warsz). 2019; 78(4):862-870. . View in PubMed

Are we overtreating intraductal papillomas? J Surg Res. 2018 11; 231:387-394.. View in PubMed

Lean methods to improve operating room elective first case on-time starts in a large, urban, safety net medical center Am J Surg. 2018 08; 216(2):194-201. . View in PubMed

Value of routine staging imaging studies for patients with stage III breast cancer J Surg Oncol. 2016 Dec; 114(8):917-921. . View in PubMed

The Role of Radio Frequency Detection System Embedded Surgical Sponges in Preventing Retained Surgical Sponges: A Prospective Evaluation in Patients Undergoing Emergency Surgery Ann Surg. 2016 Oct; 264(4):599-604. . View in PubMed

Patient satisfaction with nipple-sparing mastectomy: A prospective study of patient reported outcomes using the BREAST-Q J Surg Oncol. 2016 Sep; 114(4):416-22. . View in PubMed

The role of margins in extremity soft tissue sarcoma J Surg Oncol. 2016 Mar; 113(3):333-8. . View in PubMed

High-frequency ultrasound imaging for breast cancer biopsy guidance J Med Imaging (Bellingham). 2015 Oct; 2(4):047001. . View in PubMed

Contemporary Management of Retroperitoneal Soft Tissue Sarcomas Curr Oncol Rep. 2015 Aug; 17(8):39. . View in PubMed

Malignancy rates after surgical excision of discordant breast biopsies J Surg Res. 2015 May 01; 195(1):152-7. . View in PubMed

Lymph node status in inflammatory breast cancer Breast Cancer Res Treat. 2015 May; 151(1):113-20. . View in PubMed

Comparison of radioiodine utilization in adolescent and young adult and older thyroid cancer patients Endocr Pract. 2014 May; 20(5):405-11. . View in PubMed

Has medical diplomacy reached an inflection point? Am J Surg. 2014 Mar; 207(3):315-20.. View in PubMed

Invited commentary on "A prospective study of tumor and technical factors associated with positive margins in breast-conservation therapy for nonpalpable malignancy" by Reedijk et al Am J Surg. 2013 Oct; 206(4):611-2. . View in PubMed

Trends in post-mastectomy reconstruction: a SEER database analysis J Surg Oncol. 2013 Sep; 108(3):163-8. . View in PubMed

The role of axillary ultrasound in the detection of metastases from primary breast cancers Am J Surg. 2013 Mar; 205(3):242-4; discussion 244-5. . View in PubMed

Identifying risk factors for surgical site infections in mastectomy patients using the National Surgical Quality Improvement Program database Am J Surg. 2013 Feb; 205(2):194-9. . View in PubMed

Effect of immediate reconstruction on postmastectomy surgical site infection Ann Surg. 2012 Aug; 256(2):326-33. . View in PubMed

Accuracy of predicting axillary lymph node positivity by physical examination, mammography, ultrasonography, and magnetic resonance imaging Ann Surg Oncol. 2012 Jun; 19(6):1825-30. . View in PubMed

Ductal carcinoma in situ (DCIS) of the breast: perspectives on biology and controversies in current management J Surg Oncol. 2012 Feb; 105(2):212-20. . View in PubMed

Sentinel node biopsy alone for node-positive breast cancer: 12-year experience at a single institution J Am Coll Surg. 2011 Jul; 213(1):122-8; discussion 128-9. . View in PubMed

The crux of the confusion about screening mammograms J Surg Oncol. 2010 Nov 01; 102(6):547-8. . View in PubMed

Neoadjuvant therapy for breast cancer J Surg Oncol. 2010 Mar 15; 101(4):283-91. . View in PubMed

Neoadjuvant therapy for locally advanced cancer J Surg Oncol. 2010 Mar 15; 101(4):282. . View in PubMed

Psychological impact of recall in high-risk breast MRI screening Breast Cancer Res Treat. 2009 May; 115(2):365-71. . View in PubMed

Volunteerism and its role on International cancer control J Surg Oncol. 2009 Mar 01; 99(3):127-8. . View in PubMed

Melanoma J Natl Compr Canc Netw. 2009 Mar; 7(3):250-75. . View in PubMed

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text:
Poetry in the Light

IMG_5652 IMG_5651

October is Breast Cancer Awareness Month!

I’ve shared my family’s experience with breast cancer, so I was honored when Echo Design asked me to style their beautiful Poetry in the Light scarf and share it with you all!

Echo designed the peony-print silk scarf in collaboration with The Breast Cancer Research Foundation, founded by Evelyn Lauder. {Fun fact: Evelyn Lauder is credited as one of the creators and popularizers of the pink ribbon as a symbol for breast cancer awareness!} The scarf’s peony design was inspired by one of Evelyn’s photographs, called “Poetry in the Light,” and was originally created as a gift for guests at the Foundation’s annual Hot Pink Party.

Now the timeless beauty is available to ladies everywhere! It retails for $85, and Echo will donate $10 from the sale of every Poetry in the Light scarf to The Breast Cancer Research Foundation. It’s available for purchase at www.echodesign.com, and at select retailers.

I love fashion for a cause!

About The Breast Cancer Research Foundation:

The Breast Cancer Research Foundation®, founded by Evelyn H. Lauder in 1993, is an independent not-for-profit organization committed to funding scientific research to achieve prevention and a cure for breast cancer in our lifetime. In October 2011, BCRF awarded $36.5 million to 187 scientists across the United States, Canada, Latin America, Europe, the Middle East, Australia, and China. With over 90 cents of every dollar donated currently being directed to breast cancer research and awareness programs, BCRF continues to remain one of the most fiscally responsible charities in the country. BCRF holds a 4-star rating from Charity Navigator, its tenth such designation since 2002. Additionally, BCRF is the only cancer organization designated as “A+” by CharityWatch. For more information about BCRF, visit http://www.bcrfcure.org.

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  1. 10.15.13

    Bank teller Sajma Furney is sincerely excited about christian louboutin cakes, snowboarding, belly dancing.

    In addition she favors travelling and exploring new locations as an
    example, to Maite.

  2. 11.4.12

    So pretty!

  3. 10.8.12

    Love the outfit! very pretty and refreshing

  4. 10.7.12

    You look very pretty! Great color combination!

  5. 10.6.12
    WhenJmetK said:

    The scarf is beautiful, a great addition to any wardrobe and goes great with your outfit

  6. 10.6.12
    Jupe said:

    Such a beautiful smile in that first picture! And I love the pink tones to this outfit, so sweet and pretty with your skin!

    <3 Cambria

  7. 10.5.12

  8. 10.5.12

    Love the cause and the scarf…. Big fan pleaseeeee see my blog <3 new at the fashion blogging :)

  9. 10.5.12
    jmcvl said:

    That scarf is so beautiful. Looks like you could actually pair it with quite a few difference outfits too. Affordable and donations to a great cause. Whats not to love. Equally love your styling too- its so elegant and feminine. You are Such a pretty thing! X

  10. 10.5.12

    pretty scarf. i would have been stuck on how to style it, but you did a great job!

  11. 10.5.12
    arayofsun said:

    You’re gorgeous! Such a cute and timeless outfit!

  12. 10.5.12
    fashionforlunch said:

    Great cause! And a great scarf!