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Difference between revisions of "User:Z3332339"

From Embryology
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==Lab Assessment 9==

Revision as of 00:20, 15 October 2014

Welcome to the 2014 Embryology Course!

Links: Timetable | How to work online | One page Wiki Reference Card | Moodle
  • Each week the individual assessment questions will be displayed in the practical class pages and also added here.
  • Copy the assessment items to your own page and provide your answer.
  • Note - Some guest assessments may require completion of a worksheet that will be handed in in class with your student name and ID.
Individual Lab Assessment
  1. Lab 1 Assessment - Fertilization References
  2. Lab 2 Assessment - Uploading a Research Image
  3. Lab 3 Assessment - Researching your Project Sub-Heading
  4. Lab 4 Assessment - Cord Stem Cells
  5. Lab 5 Assessment - Abnormalities
  6. Lab 6 Assessment - Group Work (As announced in the lecture, No individual assessment item for this Lab, but I do expect you to have added content to your Group project by tomorrow's Lab.)
  7. Lab 7 Assessment - Endocrine+Teeth
  8. Lab 8 - Genital
  9. Lab 9 - Peer Assessment
  10. Lab 10 - Sensory Development
  11. Lab 11 - Stem Cells
  12. Lab 12 - Stem Cells Presentation (see preparation information)
Lab 12 - Stem Cell Presentation Assessment More Info
Group Comment Mark (10)
  • Lots of effort to place article in larger context
  • Slide lay out could be improved: lots of empty space, use larger images and talk through them
  • Results presentation a bit convoluted. Try to finish discussion of each experiment with a clear conclusion.
  • Repetition of information towards the end
  • One presenter had an unprofessional style of presentation
  • Good well-structured presentation
  • Good introduction
  • Methods discussed separately. Try to avoid this, and incorporate in discussion of experiments. Not sure if technology was understood very well.
  • Good well-structured presentation
  • Do not discuss methods as a separate section
  • Discussion of results not always very clear, comprehension?
  • Good well-structured presentation
  • Lots of text on slides, improve talking through images, blow up images
  • Good discussion
  • Good well-structured presentation, amount of text on slides relatively good.
  • Figures too small, discussion bit convoluted
  • Slightly over time
  • Good comprehension and well-structured presentation.
  • Too much text on slides
  • Experiments discussed in a lot of detail. Try to be more concise and discuss aim of experiment, approach, summarize results, conclude.
  • No talking through figures
  • Good well-structured presentation, great introduction, inclusion of images in presentation done relatively well.
  • Methods discussed separately. Incorporate methods in discussion of the experiments in the results section.
  • Try not to depend too much on text on your slides
  • Talking through results images was not very clear, comprehension?
More Useful Links
Student Projects
Group 1 Respiratory User:Z3330991 User:Z3332339 User:Z3333429 User:Z3372817
Group 2 Renal User:Z3463310 User:Z3465141 User:Z3465654 User:Z5030311
Group 3 Gastrointestinal User:Z3414515 User:Z3375627 User:Z3415141 User:Z3415242
Group 4 Genital User:Z3415716 User:Z3416697 User:Z3417458 User:Z3417753
Group 5 Integumentary User:Z3417796 User:Z3417843 User:Z3418340 User:Z3418488
Group 6 Endocrine User:Z3418702 User:Z3418837 User:Z3418698 User:Z3414648
Group 7 Neural User:Z3418981 User:Z3419587 User:Z3422484 User:Z3374116
Group 8 Musculoskeletal User:Z3418779 User:Z3418718 User:Z3418989
Student Projects Fetal Development of a specific System.
2014 Course: Week 2 Lecture 1 Lecture 2 Lab 1 | Week 3 Lecture 3 Lecture 4 Lab 2 | Week 4 Lecture 5 Lecture 6 Lab 3 | Week 5 Lecture 7 Lecture 8 Lab 4 | Week 6 Lecture 9 Lecture 10 Lab 5 | Week 7 Lecture 11 Lecture 12 Lab 6 | Week 8 Lecture 13 Lecture 14 Lab 7 | Week 9 Lecture 15 Lecture 16 Lab 8 | Week 10 Lecture 17 Lecture 18 Lab 9 | Week 11 Lecture 19 Lecture 20 Lab 10 | Week 12 Lecture 21 Lecture 22 Lab 11 | Week 13 Lecture 23 Lecture 24 Lab 12
Student Projects - Group 1 | Group 2 | Group 3 | Group 4 | Group 5 | Group 6 | Group 7 | Group 8 | Moodle

Lab Attendance

Lab1 --Z3332339 (talk) 12:45, 6 August 2014 (EST)

Lab2 --Z3332339 (talk) 11:13, 13 August 2014 (EST)

Lab 3 --Z3332339 (talk) 11:12, 20 August 2014 (EST)

Lab 4--Z3332339 (talk) 11:05, 27 August 2014 (EST)

Lab 5--Z3332339 (talk) 11:05, 3 September 2014 (EST)

Lab 6--Z3332339 (talk) 11:12, 10 September 2014 (EST)

Lab 7--Z3332339 (talk) 11:05, 17 September 2014 (EST)

Lab 8--Z3332339 (talk) 11:24, 24 September 2014 (EST)

Lab 9--Z3332339 (talk) 11:10, 8 October 2014 (EST)

Lab Assessment 1

A role for carbohydrate recognition in mammalian sperm-egg binding The primary focus of this article is on the first stage of fertilization, the binding of sperm to the specialised extracellular matrix of the egg, known as the zona pelluicda (ZP). The article suggests that the mammalian egg cell has a specialised carbohydrate site on the ZP for which the sperm recognises and binds to, enabling the fusion of genetic information between these two gametes.

The article explains how it was previously thought that data obtained from mouse sperm-egg interactions could explain human sperm-cell binding. However, recent research has suggested that the mouse model cannot be directly applied to the human model. Thus, this research paper investigates sperm-ZP interactions, using humans as the predominant model in finding the specific requirements for human sperm-egg binding which couldn’t previously be explained by the mouse model.

This article also uses a review that focused on the identification of the egg binding proteins associated with the binding of human sperm to the egg. Their findings concluded identifying the role for carbohydrate recognition on the ZP. These carbohydrates have specific sequences that cause restriction of ZP glycosylation in humans that could not otherwise be explained in mouse and pig models or are not the same for humans. This finding suggests that the regulation of glycosylation could be directly correlated with the degree of organismal complexity. Evidence favouring this concept would require the sequencing of ZP glycoproteins from other mammals at different levels of the evolutionary ladder, which could be are areas of future directions for this research.

Examining the temperature of embryo culture in in vitro fertilization: a randomized controlled trial comparing traditional core temperature (37°C) to a more physiologic, cooler temperature (36°C)

The study undertaken in this article was to determine if better clinical outcomes of IVF resulted from embryo cultures in cooler temperatures (36 degrees) as oppose to the traditional core temperature of (37 degrees).

The method of investigation: retrieving eight or more oocytes from a female of 42 years of age, with infertile couples (n=52). These mature oocytes were divided into two groups to be cultured at different temperatures; one group at 36 degrees, the other at 37 degrees. The rate of development and expansion of blastocysts (volume), fertilization, aneuploidy and sustained implantation were the factors measured to in order to determine which of these conditions clinically improved the environment best for embryonic development. This could potentially change the temperatures of which in vitro fertilization takes places in clinics in the future.

However, the results concluded that IVF culture at 36 degrees does not improve the conditions for blastulation and pregnancy rates in human in IVF. Thus, maintaining the existing temperature or changing it to 26 degrees does not alter the effects or success of IVF.

--Mark Hill These articles are good and your descriptions are appropriate. We will discuss in later tutorials how to format the referencing correctly. Help:Reference_Tutorial (5/5)

Lab Assessment 2

Oocytes with Dark Zona Pelluica affect fertility

Oocytes with DZP demonstrate affect on fertility.png

Human mature oocytes with a normal (A) and dark (B) zona pelluicda. Oocytes with a DZP (dark zona pelluicda) have demonstrated a lower success of fertlization and implantation in clinical pregnancy rates in IVF/ICSI cycles. Patients with normal zona pellucida (NZP) were used as the control group.

<pubmed>24586757</pubmed>| PLoS One.

Figure 2. Human mature oocytes with a normal (A) and dark (B) zona pellucida.Scale bar (A, B): 100 µm. doi:10.1371/journal.pone.0089409.g002

Shi W, Xu B, Wu L-M, Jin R-T, Luan H-B, et al. (2014) Oocytes with a Dark Zona Pellucida Demonstrate Lower Fertilization, Implantation and Clinical Pregnancy Rates in IVF/ICSI Cycles. PLoS ONE 9(2): e89409. doi:10.1371/journal.pone.0089409

© 2014 Shi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

--Mark Hill This is a good image for the assessment and I have made some minor changes to the information associated with the file. You do not need to include the copyright and student template on your page, just with the image. (5/5)

Note - This image was originally uploaded as part of an undergraduate science student project and may contain inaccuracies in either description or acknowledgements. Students have been advised in writing concerning the reuse of content and may accidentally have misunderstood the original terms of use. If image reuse on this non-commercial educational site infringes your existing copyright, please contact the site editor for immediate removal.

Lab Assessment 3

2.Identify Current Research, Models and Findings

Physiological factors in fetal lung growth

This article looks at the current findings of different physiological factors that affect normal neonatal, functioning lungs upon during fetal development. The size of the paired organ to be able to exchange carbon dioxide with oxygen for the very first time at birth, is crucial to be able to withstand that pressure. As we know surfactant, is a lipid-protein composite. It is crucial to the function of the neonatal lung because:

A. Its high viscosity and low surface tension stabilize the diameter of the alveoli and prevent their collapse after each expiration.

B. Because the alveoli remain partially open, they are expanded on inspiration with much less expenditure of energy. [ANAT 2241 LEC 11-Respriation]

However, current research suggests that the production of surfactant which is reliant on hormonal factors, have little influence on fetal lung growth. In contrast, the following physiological lung growth factors were found to permit the lungs to express their inherent growth potential.

[this will be looked at further as the research project progresses]

Lung morphogenesis revisited: old facts, current ideas

Classical ideas -4 basic rules vs their review

Genetic control of lung development

Current concepts of lung development

Effects of hormones on fetal lung development

The fetal respiratory system as target for antenatal therapy

--[[User:Z8600021|Mark Hill] These references are more than appropriate (5/5).

Lab Assessment 4

1. An example of a use of Stem Cell Cord Therapy

Human mesenchymal stem cells MSCs (human embryonic tissue) have been used on animal models such as mice for their therapeutic qualities involved in regenerating liver tissue. This paper specifically looks at the possibility of using MSC to be used to treat degenerating organs after the discovering that MSC can be used as a substitute for liver acute failure on the mouse model. The human umbilical cord MSCs (hUCMSCs) have the capability to differentiate into hepatocyte-like cells due to their multipotence, meaning the that all the functions of the typical hepatocyte such as secretion of albumin and storage of glycogen can now be carried out from the hUCMSCs.

To imitate the environment for hUCMSCs to proliferate and differentiate into functional hepatocyte-like cells (iHeps), hUCMSCs were exposed to the growth factors, cytokinesis and chemicals. The induced i-heps demonstrated similar morphology to that of human hepatocytes, however the more significant part was evaluating their hepatic functions. Demonstration of hepatocyte function of i-Heps in vitro, is summarised in their findings as they compared i-Heps to hUCMS. 1) More glycogen was stored in i-Heps than in hUCMSC 2) 12 times more urea was produced by i-Heps than hUCMSC 3) lower levels of glycogen were stored in hUCMSC

This has had a significant clinical research relevance in treating acute liver failure and the possibility of treating other diseases as well.

2.Vascular shunts present in the embryo but closed postnatally

  1. The Foramen ovale -located between the right and left atrium.
  2. The Ductus arteriosus - located between the pulmonary artery and descending aorta.
  3. The Ductus venosus - located in the liver between the umbilical vein and IVC.

Lab Assessment 5

Abnormality of Respiratory development: Asthma

Asthma is a disease that affects 10% of the population in Australia according to the Asthma organisation of Australia. [1].This prevalence in Australia is significantly high compared to other countries. However, the cause for our high ranking amongst other countries is unknown. In this research paper, a strong association between low birth weight, short gestational age and fetal growth restriction is shown to influence the development of asthma in children.

A primary part of their research involved a cohort study on infants born between 1979-2005, and following up during different stages of their development postnatally; 3 years old, first hospitalisation for asthma, 18th birthday etc. A majority of the subjects were hospitalized for asthma during their follow up that was consistent with their 3 findings that influenced infant hospitalisation because of the disease.

One conclusion from the study was that pre-term neonates may have under developed lungs that are smaller than the fetuses who completed the full gestation period (38weeks). Incompetent lungs could be due to restricted growth factors, inhibiting full lung capacity. Fetuses that were born small yet completed the gestational period, were infants unaffected by asthma and hence hospitalisation from it. As predicted, the risk of hospitalization for childhood asthma was proportional to lower birth weights, with only 1kg making a remarkable difference. This was a similar case for shorter gestational age.

Lab Assessment 7

One of the most important developmental aspects of the male gonads is the descent of the testes. Recent research has discovered that the normal descent of the testes during male gonad development can be interrupted when exposed to paracetamol, aspirin, and Indomethacin (a nonsteroidal anti-inflammatory drug) causing cryptorchidism. Cryptorchidism is an abnormality of either unilateral or bilateral testicular descent, occurring in up to 30% premature and 3-4% term males. Descent may complete post-natally in the first year, failure to descend can result in sterility [1] . The aim of this research article was to determine whether common analgesic (pain relief drugs as mentioned above) disrupted the morphology and endocrine function of the human testis [2] .

Amongst the outcomes measured from comparing human fetal testes exposed to analgesic and those were not exposed to analgesic, were testosterone and the anti-Müllerian hormone. The number of testicular cells was then counted through histological and image analysis, as the testing of this occurred in vitro. The conclusion from this research identified that when fetuses were exposed to analgesic from pregnancy this cause disturbances in the fetal testis. These disturbances increase when small, critical age windows, such as when male gonad development takes place.

Data from a recent study of male human fetal (between 10 and 35 weeks) gonad position [3]

  • 10 to 23 weeks - (9.45%) had migrated from the abdomen and were situated in the inguinal canal
  • 24 to 26 weeks - (57.9%) had migrated from the abdomen
  • 27 to 29 weeks - (16.7%) had not descended to the scrotum

Thus, what is advised by this article is a caution concerning consumption of analgesics such as aspirin, indomethacin, and paracetamol during pregnancy that may cause an inhibition of normal fetal testes morphology and endocrine function.

[1] [2] [3]

The embryonic layers and tissues that contribute to developing teeth. The stages in tooth development include:

  • Lamina
  • Placode
  • Bud
  • Cap
  • Bell

The tissues that contribute to developing teeth include:

  • Odontoblasts
  • Ameloblasts
  • Periodontal ligament

Lab Assessment 8

Embryonic Development of the Ovary

Indifferent Stage

Much of the gonad development between males and females is analogous during embryonic development. Differentiation of the gonads (testis or ovary) occur late in embryonic development. Sexual differentiation is determined early on, where double X chromosomes in embryo will trigger the female gonad development whereas, an inherent XY chromosome will determine that the sex of this embryo will be a male. More particularly, the expression of the SRY gene on the Y chromosome determines the gender of the conceptus and signals pathways for male gonad development. Thus, when the SRY gene is not expressed, the human embryo will follow the gonad development of females.

Another contributing factor to gonad development after sex determining genes is hormone production. For example, at the urogenital sinus the presence dihyrdrotestosterone (DHT) determines males development and the absence of dihyrdrotestosterone (DHT) determines female development.

Differentiation Stage

• In the absence of the Y chromosome, female development occurs

• somatic support cells differentiate into follicle cells (instead of sertoli cells in males)

• From the intermediate mesoderm, the development of the Müllerian duct Müllerian duct persists and is stimulated to differentiate into the uterine tube, the uterus and the upper vagina. However, mesonephric ducts degenerate. The opposite occurs for the opposite sex.

• Presence of dihyrdrotestosterone (DHT)

• Absence of Anti- Müllerian hormone (AMH), since sertoli cells are not differentiated by SRY gene

• Some of the other essential genes involved in ovarian development include Wnt-4 and DAX-1

• Cortical cords extend from the surface of the developing ovary into the underlying mesenchyme during early fetal period

• As these cortical cords increase in size, primordial germ cells begin to arise> these then become primordial follicles> which contain an oogonium> proliferate and enter first meiotic division to for primary oocytes

• By the 10th week, ovaries are histologically identifiable

Human Ovary Timeline

• 24 days - intermediate mesoderm, pronephros primordium

• 28 days - mesonephros and mesonephric duct

• 35 days - uteric bud, metanephros, urogenital ridge

• 42 days - cloacal divison, gonadal primordium (indifferent)

• 49 days - paramesonephric duct, gonadal differentiation

• 56 days - paramesonephric duct fusion (female)

• 100 days - primary follicles (ovary)

Hill, M.A. (2014) Embryology Ovary Development. Retrieved October 7, 2014, from https://php.med.unsw.edu.au/embryology/index.php?title=Ovary_Development

Lab Assessment 9


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2016 Sun vs. Snow Contest for Writers

Hello gentle reader,

In February, the fantastic Amy Trueblood and Michelle Hauck are hosting the Sun vs. Snow contest for the third time. And this year, they’ve been kind enough to ask me to be one of the mentors for the contest. I’m very excited to join in the fun, and I’m very much looking forward to helping a talented writer polish their entry.

Below you’ll find a brief summary of what this contest is about, but all the details for the contest can be found on Amy’s and Michelle’s blogs. Please do read them and follow both Amy and Michelle if you’re interested in participating.

Who is this contest for?

Querying writers with a completed and polished manuscript.

When can you enter the contest?

The submission window will open on 1st February at 4 pm Eastern time. Only the first 200 entries will be accepted.

How can you enter the contest?

You’ll need to send your query and first 250 words to the contest email address. More info on how to format your entry can be found here. Please do read Amy’s advice on how to submit your entry so you’re sure not to be disqualified.

Which categories and genres are accepted?

All MG, YA, NA and Adult genres will be accepted, excluding erotica.

Who are the mentors?

There are 12 mentors, divided into two teams, and you can find out all about them here and here. I’m part of Team Sun, on Amy’s blog.

Who are the agents?

 There are 17 amazing agents ready to read the selected entries, and you can find out all about them here and here.

Anything else you should know?

Yes. You manuscript can’t have been in the agent round of any other contest. Only one submission per person is allowed.

Any other questions?

Please feel free to contact Amy and Michelle via their blogs or on Twitter. You can find Amy here and Michelle here. If you tweet about the contest, don’t forget to use the hashtag #sunvssnow. Please note that on Friday 29th January (this Friday!), Amy and Michelle will be hosting two Twitter chat sessions with the mentors at 3 pm and 9 pm EST.  Do stop in and ask all your questions to the mentors. I’ll be there, so don’t hesitate to contact me @emcastellan.

And if you have questions for me before Friday, feel free to ask in the comments section below!

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text:
From the Editors

In emerging Europe, early lockdowns worked. Why are so many people finding that difficult to understand?

We can in all reasonableness expect a vaccine against Covid-19 to go into general production by the end of this year, perhaps far sooner. What we can never alas expect to see is a vaccine against utter stupidity.

The number of people infected with coronavirus across emerging Europe remains relatively low compared to most western countries. The region’s highest number of deaths per one million people is in Estonia, at 31, far lower than in countries such as Belgium (where it is 501/1M), Spain (466/1M), Italy (391/1M) and the UK (237/1M).

There may be several explanations for the low numbers, but the decisive one seems to be the speedy move to enforce strict lockdown measures. Border closures and restrictions on movement and gatherings were introduced much earlier than in countries further west. A concerted effort to persuade citizens to wear face masks may also have helped.

It has also been suggested that eastern Europeans may be less susceptible to coronavirus infection given the prevalence in the region of the anti-tuberculosis BCG vaccine, but this theory has yet to be peer-reviewed and is far from being proven correct with any degree of certainty.

It is therefore far more likely that the more prosaic explanation – that coronavirus arrived later in emerging Europe, allowing the countries of the region to learn from the mistakes of Italy and institute lockdowns when there were just a handful of cases – has contributed most to the relatively successful way in which the virus has been contained.

This relative success however has fed the idea (at least in more conspiratorial and less well-educated circles) that the threat posed by Covid-19 has been overstated from the very beginning and that there was never any need for lockdown at all. Ergo, all restrictions on personal movement, on commerce and on public life in general should be lifted immediately.

The most vocal advocate globally of what we might call the It’s not turned out as bad as some people said theory is US president Donald Trump, who at the weekend was criticised by Jay Inslee, the governor of Washington state, for supporting protests against stay-at-home measures, saying that such messaging from the president was “dangerous”.

In emerging Europe, the leading proponent of the theory is the remarkable president of Belarus, Alexander Lukashenko.

On April 13, Lukashenko argued that no one in the country was dying or would die of the disease. “Nobody is going to die of coronavirus in our country. I’m announcing this publicly. It’s my firmly held conviction,” he said.

So far, 47 people have died in Belarus of coronavirus, although Lukashenko disagrees: he claims that patients who have Covid-19 die of previously existing chronic illnesses, and that coronavirus only creates an environment in which those conditions develop faster.

In Romania, a senator and former prime minister, Calin Popescu Tariceanu, currently the leader of the ALDE party, said last week when voting against the extension of lockdown measures that “there are some counties in Romania where the virus is almost non-existent”.

He appears not yet to have made the link between lockdown measures and the prevention of further contagion. Is it that difficult? Or is there simply a political unwillingness to recognise facts?

Whatever the reason, such statements are stupid and, as Governor Inslee points out, dangerous. The facts are clear: until there is a viable vaccine, there is no way other than social restriction to stop the spread of the virus. Of course, whether full lockdown is feasible to maintain for many months is debatable, and it is possible that some countries may fluctuate between rigid and less rigid measures for some time. Czechia and Poland have already begun to relax some restrictions: Czechia has a timetable that could see all businesses (including bars and restaurants) reopen by the end of June.

However, Czechs have also been warned by their health minister that they should expect to take their holidays at home at this year, and any new spike in case numbers will see restrictions put back in place very quickly.

There is also the question of what happens when a vaccine does become available. While most anti-vaxxers have been very quiet over the past few weeks (they are, after all, getting a preview of their vaccine-free world) they can be expected to once again leap into action the moment the idea of mass anti-coronavirus vaccination is mooted.

Serbian tennis star Novak Djokovic has already said that his opposition to vaccinations may get in the way of his return to competitive tennis.

“Personally I am opposed to vaccination and I wouldn’t want to be forced by someone to take a vaccine in order to be able to travel,” the world’s leading tennis player said in a live Facebook chat with several fellow Serbian athletes at the weekend.

Besides proving – not for the first time – that sporting prowess and common sense do not go hand in hand, Djokovic raises an issue that has yet to be discussed at either national or international level: what should be done with those who refuse vaccination?

We probably have a few months to consider a more measured answer, but I presently fail to see any option beyond issuing some kind of card to those who have been vaccinated, allowing their free movement, while keeping the non-vaccinated out of public life.

And yes, that will include tennis tournaments.

Unlike many news and information platforms, Emerging Europe is free to read, and always will be. There is no paywall here. We are independent, not affiliated with nor representing any political party or business organisation. We want the very best for emerging Europe, nothing more, nothing less. Your support will help us continue to spread the word about this amazing region.

You can contribute here. Thank you.

emerging europe support independent journalism


text:
JobKeeper 2.0 Extension Fact Sheet.

On 21 July 2020, the Australian government announced an extension and new updates to the JobKeeper payment. This announcement brings a new set of changes and a new wave of uncertainty for employers. As with any new change, you’re probably asking yourself, what is the JobKeeper extension, what’s changed and what does it mean for my business and team?

To help, we’ve unpacked the changes to help you navigate these uncertain times.

What’s covered in the JobKeeper 2.0 Extension Fact Sheet?

 Eligibility criteria for JobKeeper 2.0 extension

✅  The new payment rates For JobKeeper 2.0 extension

✅  What it means for casual and part-time workers

✅  Worked examples for different scenarios

Awards - Linkedin - HRD - Deloitte
JobKeeper 2.0 Extension - Employment Hero
To download the JobKeeper 2.0 Extension Fact Sheet, simply enter a few details:

Who is Employment Hero?

Employment Hero is a complete HR management solution for small to medium businesses. Founded in 2014 by employment lawyer, Ben Thompson, we aim to make employment easier and more rewarding for everyone.

We empower businesses by providing automated solutions for employee management and engagement, payroll and employee benefits. Our platform reduces admin time on managing people by up to 80%, time spent on payroll by up to 60% and time spent onboarding a new hire to just minutes.

Employment Hero powers over 4,000 business and 135,000 employees. Together we want to build a better world at work.

Watch our video.

menumenu_close Menu


text:
Nov 21st, 2011 (India) : Empxtrack, HRIS has been ranked in the TOP 5 bsoco (business software comparison) awards 2011 by the world wide user community.

Saigun Technologies Web- Based HR software in SaaS model –Empxtrack , has once again proved its mettle in the global market.

When approached for comments, Tushar Bhatia, the chief architect of Empxtrack and President of Saigun Tehnologies said: “We are pleased with this world wide recognition. Once again our quality of work is being appreciated in the global market. It is indeed a recognition of our team’s efforts in making Empxtrack, a web-based HR software, both user friendly and cost effective.”

About Saigun Technologies and Empxtrack :
Saigun is a technology group focused on designing HR Management solutions. Saigun pioneers development of integrated, flexible and on-demand solutions for management of human capital. It provides technology to many Fortune 500 companies for various requirements in HR.

Saigun’s flagship product Empxtrack is a next generation software for Human Resource and Talent Management. The leader among integrated web-based solutions for HR, Empxtrack is powerful enough to handle all 18 functions of HR department through its single window interface and provides comprehensive analytics for critical decision making. Designed as a SaaS (software-as-a- service) offering, Empxtrack requires Zero-to-minimum investment in hardware and other software components, making it first choice of the organizations that require quick to use solutions with minimum investment in technology.

For further information contact:
India Office
Empxtrack Division
Saigun Technologies Pvt. Ltd.
A-27/E, Sector 16
NOIDA – 201 301, India
Phone: +91 120 473 7900
Fax: +91 120 251 0908
Email: [email protected]

US Sales Office
Empxtrack Division
Saigun Technologies
One Lincoln Centre
18W140 Butterfield Road
15th Floor
Oakbrook Terrace, Illinois 60181
United States
Phone: +1-888-840-2682
Fax: +1 866-825-3204


text:
The Vice Rags

From EverybodyWiki Bios & Wiki
The Vice Rags
The Vice Rags at Stosh's in 2018.jpg
The Vice Rags at Stosh's in 2018.
Background information
OriginJersey City and Asbury Park, New Jersey, U.S.
GenresAlternative rock, garage rock
Years active2017–present
LabelsMint 400 Records
Associated actsAcid, The Blakes, Kid With Man Head, Mars Needs Women, Readymade Breakup
MembersJoe Chyb
Gay Elvis
Jack Roberts
Paul Rosevear

Listen to songs of this musical artist The Vice Rags or Buy album of him/her on amazon

The Vice Rags are an American rock band that is from New Jersey.

Paul Rosevear and Joe Chyb grew up in North Brunswick, New Jersey, while Jack Roberts and Gay Elvis grew up together in Hillsborough, New Jersey. They met while performing in prior bands, and together they play a blend of "tribute to the '50s and '60s sounds that influenced the '70s and '80s," and are classified as bluesy, garage rock and fuzz rock.[1][2] They draw comparison to U2, Echo & the Bunnymen, Psychedelic Furs and the Clash. The Vice Rags describe themselves as a "breath of fresh, New Jersey Turnpike air," and Phil Shephard of Speak Into My Good Eye calls them "a little Jersey, a little Petty and a lot of Rock-n-Roll."[2][3]

They released a self-titled EP in November 2017, which was produced by Paul Ritchie and recorded at Insidious Sound Studio in Neptune.[3][1] It includes "some warm, classic-sounding tracks that will satisfy your most staunch rock 'n' roll crate-digging purists[,] alongside wilder, brasher songs," as described by Olivia Sissini for The Deli.[2] The Vice Rags is music editor Jim Testa's favorite EP of 2017. In his review, he commends "riffs that make you feel like you're out in the middle of the desert one second and rollin' through Beverly Hills the next, there's bar room boogie and a little bit of Springsteen, and that Petty thing comes back loud and clear[;] with a couple of more tracks, it would have been a contender for album of the year."[4][5]

Mint 400 Records[edit]

In 2018, the Vice Rags signed with independent label Mint 400 Records. They released the seven-track EP Hope the Neighbors are Lookin' on 27 July 2018. The EP is a re-release of their self-titled EP, with a rendition of Little Richard's "Lucille" as a bonus track. In a 2018 interview with Spill, Rosevear explains their cover was "one of the first songs we jammed on at our first ever practice; we were so happy with how we changed the cover that we kept it that way and put it on the album."[6] It was listed in New Jersey Stage's Best NJ Indie Records of 2018, and Chyb is the recipient of the Asbury Park Music Awards' Top Drummer award.[7][8]

  • Joe Chyb – drums
  • Gay Elvis – bass and vocals
  • Jack Roberts – lead guitar
  • Paul Rosevear – vocals and guitar

  • The Vice Rags (2017)
  • Hope the Neighbors are Lookin' (2018)
Appearing on


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Survival on Limit Internet with New Features in Windows 10

Microsoft since the advent of Windows 10 has received a lot of complaints from users of expensive limit Internet connections. Some solutions regarding survival in terms of tariff plans with megabyte pay were already available in the system. Another solution to this issue was introduced by Microsoft along with the next cumulative update Spring Creators Update, and this is a function of controlling Internet traffic. How can we now configure Windows 10 to not receive shocking bills from mobile Internet providers at the end of the month?

1. Limit Connectivity Solutions Before Spring Creators Update

In order to moderate the appetites of the system and third-party software in terms of access to the Internet, in the “Ten” version of Fall Creators Update inclusive we can set the connection as a limit. When setting up a limit connection, the system enters the traffic saving mode, in which data from OneDrive, Outlook and other Microsoft products are not synchronized, UWP applications are not updated, updates other than critical ones are not downloaded, other messages are disconnected from the network. For greater savings, we can disable the background activity of UWP applications that work with the Internet. And also restrict access to the network to third-party programs in their settings and use data compression modes in browsers.

Of course, these measures will help save traffic, but they will not allow you to take control of it and set a flow limit. We can limit the traffic to a specific amount of data per month only in terms of distributing updates to other computers. But by default, the configured distribution of updates stops when the connection is set as limited. What has changed in the Spring Creators Update?

2. Limiting traffic on board the Windows 10 Spring Creators Update

From now on, we can set the limit for the consumption of Internet traffic for ourselves, and for all the system software. The "Traffic Limit" function has been introduced in the "Ten", where you can specify a certain amount of data sent and received for a given number of calendar days. But this is not a radical tool with a sharp cutting down of the Internet when exceeding the established limit. Exceeding it gives the system a green light to turn off the background activity of some system functions and services. For us, users are provided with information to note - they say, and so, the specified limit has been reached. What we do next - whether to surf or not, to download something or not - we decide only ourselves. What does it all look like?

The “Data Usage” subsection as part of the “Network and Internet” section of the standard parameters previously served only to obtain statistics on traffic consumption by individual programs. In the April update, it was replenished with the settings of this very function “Traffic Limit”.

Here we can choose one or another Internet connection, it does not matter if it is wired, wireless, mobile or satellite. We press the button "Set Limit" and select the type of limit - monthly, one-time, without restrictions.

For the monthly type, we indicate the countdown date - the number of activation of the tariff plan. Then we set, in fact, the limit - this or that amount of MB or GB of data. Click "Save."

For a one-time type, we set the validity period within 60 days. And also, as in the previous case, we set the limit and save.

After which we will see reference information - how many days are left until the end of the specified period, the end date of this period, the amount of data used and the remaining amount to the designated limit.

As soon as the traffic limit is exceeded, we will see a system notification about it.

OneDrive synchronization will be immediately suspended, the background activity of a number of system services and the Update Center will stop. For the latter, the connection will be listed as limited with all the ensuing consequences - downloading only critical updates.

We can only download all updates in a row and synchronize the contents of OneDrive manually.

The “no limit” limit type is simply tracking the traffic used within a 28-day period. It does not provide for setting a limit on the amount of data, and, accordingly, the system does not react to anything at all. This is just a note of information.

The set limit at any time can be reconfigured or deleted at all.

Limiting the background activity of UWP applications within the framework of the Traffic Limit function is not provided; this feature is offered to us by a separate setting, Background Data Transfer.

The activity of universal applications is limited both within the established limit and without it. Those. we can cut down Internet access to regular Skype, the Mail, Calendar, Groove Music, People, Cinema and TV applications, and so on, we can for any connection, regardless of the restrictions configured for it. Within the framework of the established limit, the UWP application can be limited not immediately, but from the moment when 10% of the established data limit remains.

3. All Windows 10 settings for limit connections

As you can see, the “Traffic Limit” function is essentially the purpose of the connection as a limit, only with the possibility of delaying the activation of this setting. This, of course, is not an ideal tool for controlling expensive traffic, but with our informed participation it can be a pretty good solution for tariffs with megabyte payment over the free amount of data set by the provider. So now, after upgrading to Spring Creators Update, the Top Ten can offer users limited connections? These are her old and new features:

  • Establishing a connection as a limit - Windows 10 inherited this feature from Windows 8.1, and it is still a priority solution;

  • The news of the April update discussed above - the “Traffic Limit” function and settings for limiting the background data transfer;

  • Disabling background activity of individual UWP applications;

  • Disable Timeline Activity Sync. Disabling its synchronization, by the way, is not provided either in the action mode of the traffic limit, or with the limitation of background data transfer;

  • Disabling automatic updating of UWP applications and live tiles in the Microsoft Store.

    4. Effective solutions and drastic measures

    Disabling data synchronization, limiting the activity of the Update Center and UWP content is all good, but usually we, the users, are the active traffic eaters. Surely the majority of the analysis of statistics downloaded and uploaded to the Internet at the top of the list will find user software - browser, file downloader, torrent download, etc.

    The operating system is already here, no matter how reasonable it is, it will not help us. With a limited Internet connection, we need to abandon the habit of pulling everything from the Internet and look for a browser with data compression. Among the browsers that regularly support this feature are Opera and Yandex.Browser. For Chrome, there is the “Traffic Saving” extension. In Chrome, Firefox, and any browser with support for their extensions, you can install an ad blocker and a content blocker - a radical but effective solution. A regular content blocker is on board the Vivaldi megafunctional browser out of the box. We can work with content blockers in the most severe survival mode and see the Internet without pictures and animations.


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Advertising and Communication Agency specialized on providing services to foreign companies interested in business development in Russia

Deciding to make advertising in the CIS, many are faced with problems of documentation, taxation, remittances abroad. Should a non-resident pay VAT? How are taxes paid? All these questions are very important and can puzzle an unsophisticated accountant. Choosing cooperation with our agency, you can focus your attention on your business and your marketing tasks. We take care of all the problems with the documentation. You get services and do not worry about anything else. Working with the agency, you are protected from paper red tape and possible counterparty errors, and they are not that rare. Thus, cooperation with an experienced company gives you many advantages, facilitating work and document circulation.

Advertising in the CIS. Prices

The cost of placement in the CIS differs significantly from the state and many other factors, but, as a rule, it is more quiet money than in Russia with the federal placement. Naturally, everywhere there are special features, but with a competent media planning, you can significantly save budgets and time, increasing the effect of placing at times.

Advantages of working with our agency

The undeniable advantage of our agency is the availability of extensive experience in placement, confident knowledge of the specifics of the legislation of each state that is part of the CIS, free orientation in the workflow. Our media planning specialists are well versed in the CIS media services market, they understand what it is worth offering to the client, and what does not work, what media should be selected for a specific target audience, have an idea of the rating and top media.

We select every specialist of our agency with great care, only proven professionals work in our company.

It does not matter what size your business is

You can be an individual entrepreneur or a firm with 23 employees,

otherwise you can be a corporation with 1000 people in the state

You can be a start-up or a company with a rich history

You can have many branches in Russia or you can be an international company

First of all for us you are a unique CUSTOMER!

And you will get the best service!

We know how to succeed

Advertising in the CISHOOK-MEDIA will help you to plan your expenses organically, so that any expenditure on advertising in the CIS turns out to be a profit for you. Our specialists in strategic planning will develop for you such a project, which will maximally realize your goals. For our partners we provide the most worthy prices. Huge experience and thousands of projects implemented, warm and friendly relations with the leading channels and the largest sellers allow us to offer truly exclusive terms. Our agency is proud that a number of our Clients, thanks to the high quality of our services, has taken the leading positions in the Russian market. And not the last role in this played the competent help of our agency, and the work of our purchasing department. When developing a campaign, we, first of all, focus on the goals and objectives of our customers and achieve them in the most efficient and beneficial way for them.

Comfortable payment terms

Despite the high cost and significant budgets, we find for each comfortable payment terms. For long-established and trusted customers, not only special conditions and permanent exclusive discounts operate, but also a postpay system. In any case, all the wishes for payment are considered, and the most suitable method is available, the payment schedule, because first of all in our work we are guided not only by the expediency, but also by the benefit and comfort of our partners. If they come to our agency, they get quality services, competitive terms of cooperation.

Why is beneficial to work with us?

With the help of profiling we select managers, sellers, analysts, media buyers, copywriters, and creatives into the staff. They are busy with what they love. Especially relevant, these are employees who have been trained in higher education institutions, and have been carefully selected for their competence. Annually they pass courses of improvement of professional skill, participate in seminars and conferences.

Федеральная реклама на ТВ We have excellent knowledge in media business
We will create a unique promotion strategy HOOK-MEDIA advertising agency
HOOK-MEDIA advertising agency We will precisely define the target audience
We will provide exclusive conditions for placement HOOK-MEDIA advertising agency
HOOK-MEDIA advertising agency We have experience in international projects

Our specialists

Every employee of our HOOK-MEDIA advertising agency is selected for his post with special care. Most noteworthy, he passes the trial period, his knowledge is verified, his abilitis and personal qualities are assessed. HOOK-MEDIA advertising agencyHOOK-MEDIA advertising agency has a wonderful and united team that is ready to come to the rescue, which resolves the tasks clearly, quickly and effectively. Our specialists work in this field for a long time and know this business perfectly. That is why such bright creative and innovative professionals it is not easy to find, and they are worth their weight in gold. Perfection is not a gift or status, it is a painstaking process, daily work, constant trainings, improvement of skills, and of course, real purchases and arrangements. Only with this valuable, the best and incomparable experience our colleagues use to provide the highest-class service.

Which channel should I choose?

The choice of a television channel for placement is always one of the most important issues. Most noteworthy, from the choice of the channel depends the quality of coverage of the target audience, the implementation of the set goals and objectives. Specialists of our agency will develop an action plan for placing advertisements in the CIS based not only on the proven experience, but also on the basis of statistical data. If a business owner does not like a certain channel, this does not mean that placing on this channel will not help him achieve the desired results. In planning, it would be erroneous to rely on personal preferences, because the main thing after all is the research data and preferences of your target audience. Our professionals will never offer you a template promotion. After all, what helped and played into the hands of one, may not be the best choice for another. Therefore, HOOK-MEDIA develops a plan for each Client strictly individually, conducts the necessary research to reduce the risks of losing the right audience and optimize costs.

Guarantee 100%

Advertising in pressChoosing cooperation with a proven and experienced company in advertising in the CIS, you help your business to develop easily and at no extra cost. Moreover, you save time on thoughtless decisions, you optimize the means, designed to attract new infusions, find loyal customers, bypass your competitors in the struggle for leadership. If you are serious about getting the best result, then you should choose the appropriate company in your team. Professionals of our team will develop for you in the shortest possible time a plan of the most profitable and expedient actions, they will surprise you with exclusive conditions and help you deal with the most difficult issues. Entrust the advancement of your business in reliable hands and get the maximum result. Advertising in the CIS with HOOK-MEDIA will allow you to achieve maximum success.

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