text:
Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Hypoxia-inducible factors (HIF-1 and HIF-2) are two closely related protein complexes that activate transcription of target genes in response to hypoxia. Expression of HIF-1alpha and HIF-2alpha and their effects on survival under hypoxia were studied in six human breast cancer cell lines. We also evaluated the basal and inducible expression of two hypoxically regulated genes, vascular endothelial growth factor (VEGF) and lactate dehydrogenase-A (LDH-A). All of the cell lines studied expressed HIF-1alpha at various levels, but HIF-2alpha was low or absent from the more aggressive cell lines. There was an inverse correlation between HIF-1alpha and HIF-2alpha induction and clonogenic survival under hypoxia. Thus, cell lines with reduced induction of HIF-1alpha or HIF-2alpha showed high basal levels of VEGF and improved survival under hypoxia. A reduction in HIF expression was also associated with a more aggressive phenotype in vivo. To confirm these results, we carried out stable transfection of the MDA 435 cell line with human HIF-2alpha cDNA. There was no change in the growth rate in monolayer culture. However, in vitro growth as colonies and in vivo tumor growth of the HIF-2alpha overexpressing cells were significantly impaired compared with the control transfectants. Thus, despite the fact that HIF proteins are necessary for optimal tumor growth and angiogenesis in vivo, overexpression of these molecules seems detrimental to tumor growth. A balance between the angiogenic and tumor-inhibiting levels of HIF proteins may, therefore, be necessary for optimal tumor growth.

Journal article

Cancer Res

Publication Date

7106 - 7113

Animals, Basic Helix-Loop-Helix Transcription Factors, Blotting, Western, Breast Neoplasms, Cell Survival, Cells, Cultured, DNA, Complementary, DNA-Binding Proteins, Endothelial Growth Factors, Humans, Hypoxia, Hypoxia-Inducible Factor 1, Hypoxia-Inducible Factor 1, alpha Subunit, Immunoblotting, Isoenzymes, L-Lactate Dehydrogenase, Lymphokines, Mice, Mice, Nude, Neoplasm Transplantation, Neovascularization, Pathologic, Nuclear Proteins, Phenotype, RNA, Trans-Activators, Transcription Factors, Transcription, Genetic, Transfection, Tumor Cells, Cultured, Vascular Endothelial Growth Factor A, Vascular Endothelial Growth Factors


Content-Type: application/http; msgtype=response

WARC-Identified-Payload-Type: text/html

WARC-Type: response

text:
HP EliteBook x360 1030 G3 13.3" Touchscreen LCD 2 in 1 Notebook - Intel Core i5 (8th Gen) i5-8250U Quad-core (4 Core) 1.60 GHz LPDDR3-128 GB SSD - Windows 10 Pro 64-bit - 1920 x 1080 - in-Plane

  • $9,999.00
    Unit price per

Brand: HP INC

  • Processor Manufacturer: Intel
  • Processor Type: Core i5
  • Processor generation: 8th Gen
  • Processor model: i5-8250U
  • Processor speed: 1. 60 GHz

Publisher: Hp Smartbuy Notebooks

Release Date: 31-07-2019

Details: The number of devices you need to make an impact is one. Create and present your vision of success on the HP EliteBook x360 1030 with four use modes to get work done, share content, and enjoy some downtime. Ideal for mobile professionals needing best-in-class, business rugged notebooks with enhanced system and graphic performance in a managed-IT environmentWindows 10 Pro 64 Designed for where life takes youCExpress yourself in any light using the optional ultra-bright outdoor viewable display with anti-glare and ambient light sensors on the precision crafted HP EliteBook x360 featuring four inspiring use modes with remarkable audio. How life gets doneCBe ready when your day pulls you in different directions. Complete your priorities from almost anywhere with optional 4G LTE, and with anyone using the HP Premium Collaboration Keyboard supported by long battery life. Safe. Smart. Protected. CHelp protect your PC from outside threats with a comprehensive suite of security tools. Keep prying eyes away from your creations on the HP EliteBook x360 1030 with the optional HP Sure View Gen2 integrated privacy screen. Windows 10 Pro 64 Package Contents: EliteBook x360 1030 G3 Notebook PC AC Adapter Power Cord

UPC: 193424282326

EAN: 193424282272

Package Dimensions: 18.8 x 12.5 x 5.3 inches

PriceValidUntil:Stock Last

warcinfo:
isPartOf: CC-MAIN-2021-04
publisher: Common Crawl
description: Wide crawl of the web for January 2021
operator: Common Crawl Admin (info@commoncrawl.org)
hostname: ip-10-67-67-250.ec2.internal
software: Apache Nutch 1.17 (modified, https://github.com/commoncrawl/nutch/)
robots: checked via crawler-commons 1.2-SNAPSHOT (https://github.com/crawler-commons/crawler-commons)
format: WARC File Format 1.1
conformsTo: http://iipc.github.io/warc-specifications/specifications/warc-format/warc-1.1/


text:
Episode 52: Your Family Drama Dilemmas Solved!

Tips for anticipating, avoiding and tackling conflict around your wedding

On episode 52 of The One Fab Day Wedding Podcast, we're troubleshooting some of the most common family-related dilemmas, covering everything from feuding parents, to interfering siblings, to demanding cousins! Pretty much every couple we’ve encountered has experienced some kind of family conflict around their wedding, so, rather than resist the inevitable, we're dusting off our very best pieces of advice for minimising and reacting to wedding family drama. Our hope is that, after listening to this episode, you'll feel prepared to deal with all manners of squabbles and disputes, and get on with the fun parts of wedding planning!

Listen & Subscribe to The One Fab Day Wedding Podcast

Not sure how to listen? Click here!

Episode Breakdown: Your Family Drama Dilemmas Solved!

Wedding tip: Claire's tip this week is to communicate your favourite parts of your venue to your photographer, so they can arrange to take some of your wedding portraits there, if possible!

Main topic: This week, we're talking about something that, unfortunately, seems to be unavoidable during the wedding-planning period - family-based conflict! For some reason, hosting a big celebration tends to spark issues among family members (if you're unlucky, in your partner's family as well as your own!), so our aim with this episode is to give you the tips and tools to tackle them! As well as offering up our top pieces of advice for avoiding and anticipating wedding family drama, we're troubleshooting some of the family issues that we get asked about most frequently. Hopefully, by heeding our advice, you can continue to enjoy the exciting wedding-planning period in the face of any unwanted drama!

Wedding dilemma: A listener writes, “My bridal party consists of my two sisters, my groom's sister, and two of my best friends, so five ladies in total. We all live in different cities, and so I don't regularly see them all together, just one-on-one. They are all lovely and dear to me, but have very different personalities, hobbies, life situations, etc. I'm a bit nervous for our bachelorette weekend as I know that some girls aren't overly fond of each other. My thought was to go rent a cottage in the country for a weekend and tour some vineyards together. How do I get all the girls to get along with each other and have a good time? I'm nervous that it will be very awkward or things may get catty. The wine may help... but it also may not! I’m hoping to avoid a Bridesmaids cookie situation!” Our advice for this listener is to voice your concerns to one or two of your bridal party members, but go ahead with your vineyard plan (which sounds fabulous by the way!), and trust that everyone will be on their best behaviour.

Something to do when you're not planning your wedding: In this episode, Claire's recommending Laura De Barra's indispensable DIY manual, Gaff Goddess.

Thanks for listening!

Got something to add to the conversation? Shoot us a mail at [email protected]. We want the One Fab Day Wedding Podcast to make wedding planning easier and more enjoyable for you, our beloved listener, so if there's something you'd love to hear discussed on the show, or a question you'd like answered, please do drop us a line.

If you loved the episode, don't forget to rate and review the podcast on iTunes. You should also make sure you're subscribed to the podcast - that way you'll receive notifications every time a new episode is released! Oh, and if you know anyone who's engaged and planning a wedding, or a bridesmaid, groomsman, parent or wedding guest who needs a dilemma solved, be sure to tell them about the podcast and share a link.

Episode 2: Parents and Weddings - How to Deal

Episode 48: How to Deal with Bridesmaid Drama

Should Your Parents Have a Say in Your Wedding?

Our Favourite Real Weddings

How To Minimise Drama When You're Planning a Hen Party

Featured image credit: Dena Shearer Photography via One Fab Day

Click here for more episodes of The One Fab Day Wedding Podcast!

See more in:
  • 106k Facebook
  • 50k Instagram
  • 164k Pinterest
  • 17k Twitter
  • 27k Email
  • 550k Monthly


text:
Camlynn Mirror 45 Piece Everyday Flatware Set, Service for 8

Out of stock
  • Includes: (8) 5 Piece Place Settings, (1) 5 Piece Serving Set
  • Mirror finish reflects a sleek shine.
  • High quality 18/0 stainless steel for durability and rust resistance.
  • Product backed by a limited lifetime warranty and is dishwasher safe.
Jewelry for the Table™

Set Contains: (8) Dinner Knives, (8) Dinner Forks, (8) Salad Forks, (8) Dinner Spoons and (8) Teaspoons, (1) Serving Spoon, (1) Pierced Serving Spoon, (1) Sugar Spoon, (1) Butter Knife and (1) Serving Fork

Surf the sweeping divide of Camlynn Mirror. Separating two tones, the clean break cuts concave across the handle. Bend colors and tradition while keeping a modern shine with Camlynn Mirror.
Use & Care
Oneida stainless steel flatware is rust resistant, dishwasher safe, never needs polishing, and will maintain its shine for the lifetime of the flatware.

Stainless Steel Limited Lifetime Warranty:

Finest Quality Since 1880™ We stand behind the proud Oneida tradition of quality, carefully-crafted flatware. Each piece is warranted against original defects in workmanship and materials.
© 2021 The Oneida Group Inc. All rights reserved. Oneida, Anchor Hocking, and all pattern names are trademarks of The Oneida Group Inc. and its subsidiaries.


text:
Pushing Up Daisies: An Agatha Raisin Mystery (Agatha Raisin Mysteries #27) (Hardcover)

Pushing Up Daisies: An Agatha Raisin Mystery (Agatha Raisin Mysteries #27) Cover Image
This book is currently not available
Special Order - Subject to Availability

Other Books in Series

This is book number 27 in the Agatha Raisin Mysteries series.

New York Times bestseller M. C. Beaton's beloved Agatha Raisin—now the star of a hit show on Acorn TV and public television—is back on the case and poking around where she doesn't belong.

Agatha Raisin, private detective, resident in the Cotswold village of Carsely, should have been a contented and happy woman…

But in M.C. Beaton's Pushing Up Daisies, things are about to get a little less cozy. Lord Bellington, a wealthy land developer, wants to turn the community garden into a housing estate. And when Agatha and her friend Sir Charles Fraith attempt to convince Lord Bellington to abandon his plans, he scoffs, “Do you think I give a damn about what a lot of pesky villagers want?” So it’s no surprise that some in the town are feeling celebratory when Agatha finds his obituary in the newspaper two weeks later.

The villagers are relieved to learn that Bellington’s son and heir, Damian, has no interest in continuing his father’s development plans. Except the death was apparently murder, and the police see Damian as suspect number one--though Agatha finds plenty of others when he hires her to find the real killer. The good news is that a handsome retired detective named Gerald has recently moved to town. Too bad he was seen kissing another newcomer…

Soon, another murder further entangles Gerald and Agatha in a growing web of intrigue as they work with her team of detectives work to uncover the killer’s identity.

About the Author

M. C. Beaton (1936-2019), the “Queen of Crime” (The Globe and Mail), was the author of the New York Times and USA Today bestselling Agatha Raisin novels -- the basis for the hit show on Acorn TV and public television -- as well as the Hamish Macbeth series and the Edwardian Murder Mysteries featuring Lady Rose Summer. Born in Scotland, she started her career writing historical romances under several pseudonyms and her maiden name, Marion Chesney.

In 2006, M.C. was the British guest of honor at Bouchercon.

Praise For…

“Agatha Raisin is in top form in bestseller Beaton’s 27th mystery…a twisty plot, a familiar cast of eccentric characters, and a charming English country setting mean that lovers of cozy mysteries will be satisfied indeed.”
Publishers Weekly

“It’s fast paced, with lots of twists and turns, hilarity, and quiet moments when you think maybe, just maybe, Agatha will get a grip.”

More Praise for M.C. Beaton and Agatha Raisin:

"Full of perfectly pitched interest, intrigue, and charm.” —Lee Child

“Once you meet Agatha Raisin, you’ll keep coming back.”
New York Journal of Books

“A Miss Marple who enjoys drink, cigarettes, and men, Agatha displays a wit and sharp tongue that will continue to please her fans.”
Publishers Weekly

"Few things in life are more satisfying than to discover a brand-new Agatha Raisin mystery."
Tampa Tribune
“M. C. Beaton has a foolproof plot for the village mystery.”
The New York Times Book Review

"Outwardly bossy and vain, inwardly insecure and vulnerable, Agatha grows more endearing with each installment."
Cleveland Plain Dealer

"Beaton has a winner in the irrepressible, romance-hungry Agatha."
Chicago Sun-Times

Product Details
ISBN: 9781250057440
ISBN-10: 1250057442
Publisher: Minotaur Books
Publication Date: September 20th, 2016
Pages: 288
Language: English
Series: Agatha Raisin Mysteries


text:
1. One Rock Fund inception is March 6, 2020. Performance for “March” is from March 6 – March 31, 2020, for One Rock Fund, NASDAQ 100 and S&P 500. The Growth of $10,000 chart assumes the Fund’s inception date of 3/6/2020 for the indices. The returns shown do not reflect the deduction of taxes that a shareholder would pay on fund distributions or on the redemption of fund shares. Because of ongoing market volatility, fund performance may be subject to substantial short-term changes. Data from Yahoo Finance.

2. NASDAQ 100 is an index which includes 100 of the largest domestic and international non -financial companies listed on the Nasdaq Stock Market based on market capitalization. The S&P 500 is a stock market index that measures the stock performance of 500 large companies based on market capitalization listed on stock exchanges in the United States.

c/o Mutual Shareholder Services, LLC

8000 Town Centre Drive, Suite 400

Broadview Heights, OH  44147

TEL: 1-800-564-3899

FAX: 440-526-4446

Monday - Friday

8:30 AM - 5:00 PM EST

Jeff Wrona

Wrona Investment Management, LLC

P.O. Box 4773

Pinehurst, NC  28374

Please consider the investment objectives, risks and charges and expenses of the Fund carefully before investing. The Fund’s prospectus contains this and other information about the Fund and is available on this website or by calling (800)-564-3899. Please read the prospectus carefully before investing. An investment in the Fund is not a deposit of a bank and is not insured or guaranteed by the Federal Deposit Insurance Corporation or any other government agency. The Fund may be offered only to persons in the United States and by way of a prospectus. This website should not be considered a solicitation or offering of any product or service to investors residing outside of the United States.

The investment return and principal value of an investment in the Fund will fluctuate so that an investor's share, when redeemed, may be worth more or less than their original cost.

Investing in the Fund involves risks such as Equity Risk, Futures Risk, Hedging Risk, Investment Risk, Large-Capitalization Risk, Leverage Risk, Limited History of Operations Risk, Management Risk, Market Risk, New Advisor Risk, Non-diversification Risk, Options Risk, Regulatory Risk, Sector Risk, Short Sales Risk, Small- and Mid-Capitalization Stock Risk, Technology Sector Risk, Turnover Risk and Underlying Fund Risk.  Investors should carefully review the risks associated with an investment in the Fund by reading the prospectus which can be found here.  Additional information can be found in the Statement of Additional Information and Supplement which can be found here.  Understand those risks before investing.


text:
Microsoft Phone System

What is it?

Microsoft Phone System allows you to replace your on-premises PBX (Private Branch Exchange) system with a set of features that fully integrates with your Microsoft 365 cloud services. Phone System offers you call control and PBX capabilities, with options for connecting to the PTSN (Public Switched Telephone Network) to make and receive voice calls.

How to license it.

Add on licenses are licenses for specific Microsoft Teams features. They allow you the flexibility to add features only for users in your business who need them. Licenses for Microsoft Phone System are available for any business size in any sector.

For more information on Microsoft licenses

Click Here link

Phone system features:

  • Auto attendants – These can be used to create a menu system for your business that lets external and internal callers move through the system to locate and place or transfer calls to company users or departments in your business.
  • Call queues – Call queue greetings can be used when someone called in to a phone number for your business. These greeting have the ability to automatically place calls on hold and the ability to search for the next available agent to handle the call while people who call are listening to music on hold. You can create multiple call queues for your business.
  • Voicemail – When you get a Phone System license for a user, that specific user will be able to get voicemail that has been left by callers. Cloud voicemail is automatically set up once you assign a Phone system license and phone number to a user.

Additional features include:

  • Music on hold
  • Call answer/initiate
  • Call forwarding options and simultaneous ring
  • Group call pickup and forward to group
  • Transfer a call and consultative transfer
  • Transfer to voicemail mis call
  • Call park and retrieve
  • Call Phone number from search
  • Caller ID
  • Device switching
  • Presence based call routing
  • Integrated dial pad
  • Federated calling
  • Make and receive a video call
  • Cloud voicemail user settings
  • Secondary ringer
  • Distinctive ring alerts
  • Shared line appearance
  • Busy on Busy
  • Call blocking
  • Common area phones
  • Media bypass support
Get a quote

Please fill in the form below and one of our friendly team will get back in touch as soon as possible.

This form collects your name, phone number & email address so we can communicate with you after requesting a quote. Please see our Privacy Policy to see how we manage your data.
Add Review

We’d love to hear what you think, good, bad and brilliant.


text:
SAN FRANCISCO — Doctors and scientists are working furiously to find effective treatments for the illness caused by the new coronavirus but are cautioning the public not to self-medicate or hoard mentioned drugs not yet proven to work.

Despite widespread rumors, social media reports and President Trump's own optimism surrounding the effectiveness of several existing drugs, so far there are no proven treatments for COVID-19, according to the U.S. Centers for Disease Control and Prevention.

“There’s no magic drug out there right now,” Anthony Fauci, the director of the National Institute of Allergy and Infectious Diseases, said at a news conference on Thursday.

When COVID-19 treatments do arrive, they will likely fall into two categories, say experts. The first will be aimed at slowing down replication of the virus in patients early in the disease. The second will help stop the deadly autoinflammatory response in the lungs in its critical stage.

The drugs touted by the president include the malaria drugs chloroquine and hydroxychloroquine, the experimental antiviral drug remdesivir and azithromycin, a bacterial antibiotic. They remain, however, classed as “investigational therapeutics” because there isn’t enough data to show they are a safe and effective treatment for the illness. Read more here

Got questions about coronavirus? We're answering them.

“We often see antiviral therapies (that are promising) in the test tube and animal models. But before we give it to patients with confidence, we really need to see the data in humans,” said Jeffrey Klausner, a professor medicine and public health at the University of California, Los Angeles.

Anecdotal evidence may show when people are given a certain drug their condition improves or stabilizes but other factors could be at play. A person may have gotten better on their own, made it to the hospital more quickly or had fewer underlying risk factors impacting the course of the illness.

“Many drugs have been thrown out as being possibly helpful. But right now, we don’t have a good control of who’s getting it and at what stage," said said Rodney Ho, a professor of pharmaceutics at the University of Washington in Seattle who researches viral diseases and treatments. "We don’t have a complete picture yet.”

Labs and companies worldwide are busy screening likely drug candidates to see if they bind to proteins on the surface of the SARS-CoV-2 virus that causes COVID-19. The problem is, a screen only tells you whether the proteins bind, not the effects, explained Kevan Shokat, a professor of cellular and molecular pharmacy at the University of California, San Francisco.

Proteins can block or activate responses in a cell, so a drug could stop a function the cell uses to protects itself making the patient worse. It could “actually help the virus,” he said.

“There could be drugs that have no benefit, drugs that have a benefit and drugs that do harm,” Shokat said.

No one should expect immediate clarity, said Marc Jenkins, who directs the center for immunology at the University of Minnesota Medical School in Minneapolis.

“Every possible strategy will be tried," he said. "I suspect that’s going to be confusing for a while because there will be so many things being tried."

Tricksters in white lab coats, phishing emails: Be wary of coronavirus-related scams, officials warn

What does the coronavirus do to your body? Everything to know about the infection process

Antivirals to hit COVID-19 early

Patients with COVID-19 go through a series of stages in their illness. Exact percentages are impossible to know yet but general patterns are beginning to emerge.

For some of those infected, there are few to no symptoms. By far the largest group currently visible to medical professionals are those who present with fever, headaches and cough, and in some cases shortness of breath. Most will get better on their own.

Currently, it appears about 15% of those infected go on to have severe illness and need to be hospitalized. Another 5% become so ill that they must be treated in an intensive care unit.

Antiviral drugs would be used early on in the infection to slow or stop the virus from reproducing in the patient’s body, allowing the immune system to respond, shortening illness duration and halting progression to more severe forms of the disease.

Stay connected, even when we're all apart. Join our Coronavirus Watch Facebook group.

Such treatments would be similar to antiviral medications given at the onset of the seasonal flu, such as Tamiflu. Available only by prescription, these drugs, taken within two days of becoming sick, can lessen fever and flu symptoms and shorten the length of illness by about a day.

While numerous possible antivirals that might work against the virus have been in the news, none have been tested to ensure they work against the disease or are safe.

These include remdesivir, chloroquine and hydroxychloroquine, a combination of two HIV drugs, lopinavir and ritonavir and a triple combination of lopinavir and ritonavir plus interferon-beta. Favilavir is being tested in China.

Antivirals are often given in combinations to help decrease the chance the virus can survive and mutate into an untreatable form but they take longer to test.

“Combinations take a long time, you have check (the safety of) each drug at different doses in combination with other drugs in different doses,” said Shokat.

Drugs to halt the cascade of illness

COVID-19 patients with severe illness can develop acute respiratory distress syndrome, or ARDS. This extremely serious syndrome isn’t caused by the virus but by the body’s response to it.

The inflammatory response can include the release of chemicals that can trigger fever and low blood pressure. It can also cause small blood vessels in the lung to leak fluid and fill up the alveoli, the tiny air sacs in the lung that process oxygen and bring it into the bloodstream.

“The vast majority of patients who die from COVID-19 are dying from ARDS,” said Michael Matthay, a professor of medicine and expert on the syndrome.

As the COVID-19 pandemic grows researchers are focusing drugs including monoclonal antibodies that bind to molecules that cause or worsen the cascade of symptoms.

Some of the drugs being investigated include Actemra (tocilizumab) and Kevzara (sarilumab) – both used to treat rheumatoid arthritis – and the experimental drug gimsilumab.Others are being investigated.

In the meantime, experts urge people to remain calm and not experiment themselves with unproven drugs that could have side effects worse than the disease itself.

“Every drug has toxicity, it could make you worse or it could make you better," said Shokat. "That’s why drugs take a long time to develop – because we have to make sure."

Contact Elizabeth Weise at eweise@usatoday.com

Get daily coronavirus updates in your inbox: Sign up for our newsletter now.


text:
Explore Interactive technology bringing collaborative STEM learning to pandemic-isolated students

WEST LAFAYETTE, Ind. – A Purdue University startup is turning game play into serious learning for elementary students away from classrooms during the COVID-19 pandemic.

Explore Interactive markets an augmented reality platform to help students learn about science, technology, engineering and mathematics (STEM).

“Our newest product, MindLabs, extends the foundational Explore platform to allow kids to collaborate remotely on engineering and design of circuits,” said Amanda Thompson, CEO of Explore Interactive.

Explore Interactive has worked with educators and elementary students from across the U.S. in the development of the MindLabs platform, which lets children work together to solve hands-on STEM challenges and conduct open-ended design and play.

Now, the founders of the startup have partnered with the Museum of Science, Boston; and Homewood Science Center, located near Chicago, to host a virtual STEM camp.

“There is no better time to empower racially and ethnically diverse children to see themselves as scientists,” said Heather Gunsallus, vice president of STEM education at the Museum of Science, Boston. “The team at the Museum of Science, Boston, is thrilled to support the vital work of Purdue, Explore Interactive and Homewood Science Center with the students in Chicago’s Southland.”

The virtual camp will take place the first week of August for students 8-12 years of age. Thompson will lead virtual sessions, and then the students will complete projects on their own.

 “In spite of these challenging times, we are able to fulfil our mission of inspiring scientific wonder, learning and pursuit,” said Edie Dobrez, executive director of the Homewood Science Center. “We are honored to work with esteemed colleagues at Purdue and the Museum of Science, Boston, to offer “Augmented Reality: Northern Lights” for our racially and ethnically diverse student population in Chicago’s Southland.”

Thompson said the MindLabs platform unlocks the potential of augmented reality to deliver analytics of soft skills like collaboration and hard skills like systems thinking through applied, hands-on design and troubleshooting, a far more effective approach, it says, compared with worksheets and multiple-choice tests.

“In the current remote learning environment, MindLabs is a solution for teachers who have very limited options for students to engage collaboratively on STEM projects,” Thompson said.

Thompson and her team conducted educational research with researchers at the INSPIRE Research Institute for Pre-College Engineering at Purdue under SBIR funding from National Science Foundation, the National Institutes of Health and Elevate Ventures.

Explore has received support and guidance from the Purdue Foundry, an entrepreneurship and commercialization hub housed in the Convergence Center for Innovation and Collaboration in Purdue’s Discovery Park District, adjacent to the Purdue campus.

About Purdue Research Foundation

The Purdue Research Foundation is a private, nonprofit foundation created to advance the mission of Purdue University. Established in 1930, the foundation accepts gifts; administers trusts; funds scholarships and grants; acquires property; protects Purdue’s intellectual property; and promotes entrepreneurial activities on behalf of Purdue. The foundation manages the Purdue Foundry, Purdue Office of Technology Commercialization, Purdue Research Park, Purdue Technology Centers and University Development Office. In 2020, the IPWatchdog Institute ranked Purdue third nationally in startup creation and in the top 20 for patents. The foundation received the 2019 Innovation and Economic Prosperity Universities Award for Place from the Association of Public and Land-grant Universities. For more information about involvement and investment opportunities in startups based on a Purdue innovation, contact the Purdue Foundry at foundry@prf.org.

Writer: Chris Adam, 765-588-3341, cladam@prf.org

Amanda Thompson, athompson@exploresupport.com

Source link

Leave a Reply

Your email address will not be published. Required fields are marked *


text:
If youve just bought a new car or kitted out all of your employees with new company vehicles, its only naturally to have concerns about keeping you new cars safe. A vehicle is a valuable commodity after all, which could potentially make it a target for thieves. To help you rest easier at night, you dont need a Fort Knox-style secure garage in which to keep your car, nor do you need an expensive CCTV security system. All you need is a good insurance policy and one other very clever, super techy trick up your sleeve  a GPS car tracker.

How GPS trackers work

A GPS tracker can act in just the same way as a comprehensive insurance policy. You might not ever need to use it to actively track a vehicle, but it can give you great peace of mind to know that its there. GPS trackers are designed to be very discreet, so theres no big flashing beacon to let everyone know that the vehicles location is being monitored. Black in colour and compact in size, they can be placed in many locations in and on a vehicle. Some are even waterproof, so they can withstand the elements. Once activated, a GPS tracker starts to report on its location right away, sending data to a secure remote server which you can then access via a range of devices.

Types of trackers and ways of staying in the loop

One of the most popular types of GPS trackers is one that gives you real-time access to the vehicles location. This means that you can log into your own private tracking console and see where the vehicle is at any given moment. Miraculously, you can do this from anywhere in the world as long as you can get online, which can offer great peace of mind for those holidays and business trips away when your car has to be left behind. If you dont need such intensive tracking, there is another option. SMS vehicle trackers allow you to check in with your vehicle. When you send a text requesting the vehicles location, a text is sent right back to let you know where it is. So, if your vehicle goes missing, this information could be all you need to inform the police and track it down.

Vehicle trackers for business

GPS trackers are not only handy for private car owners, but they are also commonly used by businesses wanting to look after their fleets or keep an eye on company cars. They can potentially be used to negotiate with insurers to drive policy premiums down, as well as offering a good level of security. However, trackers can also be used to monitor suspicious employee behaviour, carry out training, improve efficiency of everyday business processes and many other very useful things. If a vehicle has any value to you, either financially, emotionally or from a business perspective, its well worth protecting it with a GPS tracker.   Image credit: Wiki Commons


text:
Learn Inspire Connect

Join Us Today!
  • Coffee Break Webinars

    ‘Be Inspired and learn something new in our series of short, weekly webinars .

    Register now or watch back
    Rated 1 times
    Coffee Break sign up >>
  • Bradt Guide or El Dorado Rum Giveaway

    The Guyana Tourism Authority will be giving away the Bradt Guide to Guyana or a bottle of El Dorado Rum to the first 40 agents to complete the course. *There is a limit of 15 Bradt Guide books to give

    More Info
    Rated 5 times
    Take the course to win
  • Travel Agent Priority Survey

    We love to hear directly from our travel agents! Please take a few minutes to complete the brief survey below to give us the scoop on your top-of-mind destinations and hot industry topics...

    More Info
    Rated 1 times
    Take Survey
  • The Inland Sea, SETOUCHI, Japan

    Welcome to Setouchi training course! Setouchi is a beautiful destination located in the west of Japan. Discover the authentic Japan in the calm inland sea and its islands.

    More Info
    Rated 1 times
    Launch course

Complete a course for a chance to win fabulous prizes!

Rewards & Achievements

Pass relevant and interesting travel product courses to win exciting prizes from globally recognised travel brands, receive certificates, rate courses and earn achievement badges.

Find out More

Create an Academy

Choose from several courses to create a product training Academy for your agency to make your training fun, relevant and help to boost sales.

Find Out More

Highlights from OTT Partners around the world

View Webinars


text:
Plumber McCarrs Creek

Commercial & Residential Plumber McCarrs Creek

On The Job Plumbing is a leader in all areas of plumbing, hot water systems, draining and strata plumbing. Our team of plumbers service McCarrs Creek and will arrive at every job with a stocked truck and plumbers ready to work. Our plumbers offer a range of plumbing services for residential, commercial and strata properties in McCarrs Creek. We know how hard it is to work with a reliable plumber in McCarrs Creek, that’s why On The Job Plumbing is your #1 plumber for all your plumbing issues.

We pride ourselves on excellent customer service and will ensure that you are satisfied with the work completed. Plumbing is not just a job to us, but a philosophy applied to every area of our lives. Our mission at On The Job Plumbing is to provide high quality workmanship of the highest standards, working together to provide you with outstanding service. We deliver a trusted service by every member of our team.

    Plumbing Services

    Our main services focus on commercial, residential and strata plumbing. We have worked on thousands of properties so you can be reassured that your plumbers at On The Job Plumbing are qualified and have the knowledge to repair your plumbing system quickly.

    Residential Plumbing

    Your home is important to us, that’s why we will reach your McCarrs Creek property swiftly and repair the plumbing issue immediately. We ensure your McCarrs Creek home is performing at its optimum level at all times. Our highly trained plumbers will fix any blocked drains, leaking taps, gas and hot water systems and assist with dishwater and toilet installation. When you work with On The Job Plumbing, you can have peace of mind that you will receive high quality customer satisfaction.

    Commercial Plumbing

    At On The Job Plumbing, we know that commercial properties can be a lot to maintain, that’s why it is important to have your local McCarrs Creek plumber regularly perform a maintenance check to ensure your property is well looked after. We specialise in the installation of grease traps, routine maintenance, thermostatic mixing valves, back flow prevention and survey reports. Our team of plumbers have worked on a range of commercial projects for gyms, industrial developments, warehouse projects, retail, offices, school and cafes in McCarrs Creek.

    As we continue to provide high quality work, we have gained a reputation of being a reputable plumbing companying offering a premium service.

    Strata Plumbing

    Our team of plumbers facilitate all areas of strata maintenance (repairs, ongoing care, installation and replacements). We pride ourselves on delivering the highest quality of preventative care maintenance to properties of McCarrs Creek. Our strata team can perform an evaluation of your facility to inspect the level of quality, strength and condition of your building structure. We will identify if there are any hazardous issues your building may be subject to.

    Our team is always available for any serious situations.

    Contact On The Job Plumbing In McCarrs Creek

    Contact our team of skilled plumbers and we will reach your McCarrs Creek property swiftly, repairing your damaged plumbing system promptly. We have the latest technology and equipment to ensure we can tackle any problem. We will always tidy up after every job, ensuring there is little to no disturbance to your day to day activities during to job.

    Contact our team and one of our friendly team members will be more than happy to assist you.

    Book Now


text:
On Yer Bike Cycles Logo
Onyerbike Burnley: 01282 438855
Onyerbike Lancaster: 01524 60554
Giant Blackburn: 01254 662440
Blackburn, Burnley & Lancaster Stores are OPEN during lockdown, please see the current opening times, due to the covid 19 pandemic these may differ
***At this present time we are not accepting internet orders or delivering bikes outside of the Lancashire area***
<< | < | > | >>

RALEIGH Motus Grand Tour Low Step Hub 2020

RALEIGH Motus Grand Tour Low Step Hub click to zoom image

Price Match
Model Year 2020
Options 46cm (26" Wheel) Blue
46cm Blue
50cm Blue
Frame Alloy frame AL6061
Forks Suntour Nex suspension fork 50mm travel
Rear Derailleur Nexus 7 speed hub gear
Chainset Raleigh Alloy Bosch crank set
Chain KMC single speed
Cassette Shimano 22T sprocket
Headset Low Stack semi integrated
Stem Adjustable angle Alloy
Handlebars Comfort XLC Handlebar Black
Brake Leavers Tektro Hydraulic disc brake
Hubs Black 36 hole disc brake compatible
Front Wheel Alloy 36 hole black disc QR
Rear Wheel Shimano Nexus 7-speed disc
Tyres Mitas 700C x 42 with reflective stripe & puncture protection
Seat Selle Royal Milo +
Seatpost Alloy Seatpost 30.9
Pedal Comfort Pedals with Anti Slip
Miscellaneous Mudguards: Full mudguards
Rear Carrier: Alloy Rack
Lighting: AXA front and rear lights
Extras: Kick Stand, charger
Brakes Tektro Hydraulic disc brake
Motor Bosch Active Line Plus
Battery Bosch Power Pack Frame Mount 500Wh, 36V
Range:up to 225km from Eco mode
Display Bosch Intuvia display with operation unit & push-assistance
Wheel Size 700/26
Gearing 1x7
As with any product, specification is subject to change without prior notification. You are advised to confirm current specification before buying.
We have placed cookies on your browsing device to enable this website to function correctly.
Further usage of this website indicates you are happy for us to do this..
Find out about the cookies we have set and how we use them.

Signup for our latest
offers and news


text:
Lessons and the future of the #OromoProtests

Written by OPride Contributor

(OPride) In his book The Dictator’s Learning Curve, journalist William Dobson writes, “revolutions, if they are to be successful, require planning, preparation, and an intelligent grasp of how to anticipate and outwit a repressive regime that thinks of little beyond preserving its own power.”

As activists around the world get more sophisticated with the use of technology and out-organize repressive states, governments have also learned to wait it out and sup momentum out of otherwise formidable movements.

In a sense, time seems to be the worst enemy for activists. Too often passion burns out and social movements falter as quickly as they begin. In the last five years, horizontal movements such as Occupy Wall Street and the Arab Spring used social media to mobilize a critical mass and proved more effective than states. However, they failed to overcome this test of time.

In one of the least connected corners of the world, students in Ethiopia’s Oromia region have also uncovered and harnessed this power of technology. Beginning in mid-April, Oromo students across various campuses in Oromia began to peacefully protest the expansion of that country’s capital quickly getting images, videos and firsthand accounts of government crackdown out on social media.

Ethiopia criminalizes all forms of dissent and heavily monitors independent reporting. As such, the world only got a glimpse of the government clampdown on protesters via Twitter, Facebook, YouTube and Oromo-centric websites and blogs. With ongoing global solidarity rallies and petitions, the growing Oromo diaspora was instrumental in amplifying the students’ voices. From Malta to Melbourne, South Dakota to Toronto and anywhere in between, silence was not an option. Activists used #OromoProtests and #FreeOromoStudents across various social media platforms to draw attention to the repression and demand mainstream media coverage.

But, as with other social movements, the passion seems to be burning out. The government continues to hunt and imprison anyone suspected of organizing these protests, as the students begin to lose control of their movement, #OromoProtests seems to be losing more steam. Amid major world news events such as the turmoil in Iraq and Brazil’s World Cup, the ongoing arrest and alleged torture of Oromo students is not receiving the attention it so deserves. Hundreds of students have gone underground to avoid arrest. The lack of access to prison records and difficulty of getting facts on the ground weakens diaspora’s efforts to generate awareness. On June 27, the International Oromo Youth Association launched a three-day social media campaign to draw attention to ongoing arrests and demanding justice for those who were killed in the crackdown. While the group’s creative use of various modes of communication including a short documentary in English is commendable, judging from the reception even among the Oromos, momentum is clearly running out.

Future of #Oromoprotests

The road for Oromo recognition has not been easy. Under the circumstances, Oromo students can take solace in the amount and quality of the media coverage their movement garnered. Ultimately, politics is a game of patience and activism is fueled by passion. Coordination and centralized leadership is key to sustaining the movement, especially in a country as repressive as Ethiopia.

All successful non-violent movements had one similar characteristic: strong leadership. When leaders effectively articulate the goals and hopes of the movement, it creates a central message and a sense of unity. Take the Ethiopian Muslims movement for example. In early 2012, the movement appeared on the cusp of winning major concessions from the government through disciplined nonviolent movement. The activists were trained in nonviolent ways of resistance and responded peaceful to government provocations. Unable to slow down the resistance, the government arrested the protesters representatives (the Committee) in July 2012. The silent protests and sit-ins continued for months. But, with the central leadership languishing in jails, once the most sustained nonviolent movement in Ethiopia’s recent history (if not ever), it is now all but dead.

Nevertheless, the experiences offer valuable lessons for Oromo students. First, the student movement needs to solidify the non-violent stance. Nonviolent resistance requires coordination, discipline and patience to respond peacefully to an act of aggression. As such, even if the government responds with violence, the movement must respond with more peace, for violent reaction would only exacerbate the situation.

Second, the Oromo diaspora must also do more than holding rallies, writing press releases, changing profile pictures on Facebook and sending out few Twitter updates a day. A peaceful movement feeds off of ideas and intellectual conversations. Besides, given the ubiquity of information on social media networks, in order to make journalists and the international community understand the students’ position, reliable information should be gathered, synthesized and organized into easily accessible formats. The website was a great stride in that direction. But more can be done.

There were also other encouraging efforts (in places such as Minnesota) to hold community forums to discuss the best way to respond to the crisis. But those sessions must not be for mere therapeutic purposes where we express our anguish. Protesting in our respective communities gets the story out, but without a unified message the story fades. The #hungerstrike and resolutions passed by Minnesota legislature because of the community’s efforts are worth noting. While efforts to organize global day of action was also commendable, there appeared very little communication and coordination between the organizers. It would have had more effect if all Oromo activists across the U.S. went on hunger strike at the same time, and more local resolutions were passed. This would have undoubtedly received more media coverage and better response from U.S. lawmakers.

Third, have a clear message. The message should highlight the lack of human rights and less of the factional politics. The focus should be on getting the story of innocent student massacres into the international news cycle.

There were also moments where different factions of Oromo leaders sought to own the narrative. This is wrong. The students had legitimate grievances and their call for the respect of the constitution was unambiguously clear. We must put away our political ambitions and differences and focus on getting the information out to a broader audience.

Finally, it is important to seek out and build solidarity across ethnic lines. The government propaganda equates the struggle for Oromo rights with Oromo attempts to takeover the government. While many in Ethiopia fear an impending Oromo domination, Oromo students raised legitimate, constitutional and fundamental questions of group rights. This message of peace needs to be stressed to ensure all freedom advocates and those who feel unfairly marginalized or unjustly treated by Ethiopian government can join in efforts to make Ethiopia into a democratic nation. The EPRDF regime thrives by making different ethnic groups to fear one another. Instead of playing into government hands and perpetuating tyranny, rights advocates in Ethiopia must build bridges on common principles of human rights, freedom and justice. Patience and passion channeled into rational actions can go a long way in bringing change to Ethiopia. Factionalized outbursts of heated reactions benefit only the regime.

About the author

OPride Contributor

Leave a Comment

This site uses Akismet to reduce spam. Learn how your comment data is processed.


text:
Wireless Collaboration Gateway

OPS Technology carries a selection of wireless collaboration gateway products by Barco, Extron, Mersive and WolfVision, to help us to present content wirelessly from a laptop, smartphone, or tablet on a display. Select the best solutions for your needs.

Barco ClickShare CS-100

Stand-alone wireless presentation system for small meeting rooms

Barco ClickShare CSE-200

Wireless presentation system for small to medium sized meeting rooms

Barco ClickShare CSE-800

Wireless presentation and collaboration system for boardrooms and conference rooms

Extron eLink 100

Professional Grade Wireless Extender for HDMI

Extron ShareLink 200 N

Collaboration Gateway – Network Version - no WAP

Extron ShareLink 250 Series

Wireless Collaboration Gateway

Extron ShareLink Pro 1000

Wireless and Wired Collaboration Gateway

Mersive Solstice Pod

Wireless Collaboration Gateway

WolfVision Cynap

Centrepiece of the modern classroom & meeting room

WolfVision Cynap Core

Core essentials for collaboration & wireless presentation

WolfVision Cynap Pure

Bring your own device (BYOD) wireless presentation made easy


text:
How to Plan An eCommerce Re-design and Re-branding Project

Clients and prospects often ask about design: “Should I do a template or custom design? I don’t have my brand guidelines. Should I redesign my site or redo my brand? In your opinion, for an eCommerce business, when does it make sense to do a full scope redesign?

Identify what type of eCommerce store you run. Are you a reseller or a true brand, meaning you’re selling your own unique products? Depending on the choice, your plan of action moves forward with either brand guidelines or even going into a new website design. Each is going to take a completely different course.

Creating Brand Guidelines for your eCommerce Redesign

Regardless of whether you’re a true brand or a reseller, you still need to have a solid set of brand guidelines. You’re still going to have a logo, color scheme, font selection that needs to be consistent throughout the entire site.

If you’re earning several million dollars in annual revenue, you are going to need to become a brand. And just think about it. From this standpoint, Amazon, Walmart, Wayfair, Jet, House, Overstock, and eBay compete for the market share in your niche.

If you think that these brands are not your competitors, you got to think again. Search for any home appliance on Google search results and you’re going to get these brands showing upThese are known brands. One of the most effective ways that you can represent your brand online is to have a good design, UI element, and conversion elements.

If you’re earning a million dollars, what would you say? Do you need to have a brand guidelines document?

Absolutely. Look at your core demographic. See if your design supports what that core demographic needs. For example, if you are a B2B business, and if you see that most of your customers purchased ten or more items, have a multi “Add-To-Cart” functionality on your category pages. The design needs to support functionality and vice-versa.

Successful Rebranding And Designing

Let’s talk about a custom design.

Somebody comes to us, they’re saying, “We’re earning X million dollars. After growing so fast, we even paid attention to design. Now we’re going to do a redesign and now we need those brand guidelines.”

How would you do a custom redesign on an eCommerce website?

Marketers need mock-ups of the core sections of an eCommerce site. These are the homepage, category page, product page, and checkout. The mock-ups are either done in Photoshop or Figma, we’ll go ahead and we’ll review with the client to get their feedback. And again, there’s going to be some revisions, a couple of different rounds of revisions, a lot of back and forth when it comes to the design.

Small Businesses Working With a Marketing Agency: Don’t Be a Design Loser!

Trust your agency partner, especially when it comes to eCommerce because the experts look at what converts all the time. This results in ample back and forth when it comes to working with clients with design.

Markets are not thinking about your brand’s tone of voice but rather what your customers will actually click, how they will navigate, and how they will complete a purchase. Once the marketers go through these design revisions, then they go into the actual development of the design, incorporating functionality.

There’s a thin line. Here, you’re a huge brand, but there you’re a loser.

What does being a loser with design mean?

You’re stuck with the idea, design, representation of that brand that you don’t see anything else on the website. You just want it to look pretty and beautiful to wow visitors. Pretty websites do not convert.

The difference between that thin line is you can have a 0.5% conversion rate and have a beautiful wow website. Or you can have a 5%, 6%, 7% conversion rate and have a design that doesn’t wow people, but it’s clean and it’s simplified. Take the latter every single time.

The bigger the brand you are, the more leeway and creativity you have to go after that wow factor. You’re already a huge well-established brand and you know that people are going to buy from you anyway. They will go through the hassle of navigating through your site, look at the cool features, and purchase. Whereas if you’re trying to now scale your brand, you can not go out of the gates with a website that has inconvenient navigation.

Look at how fast Amazon loads. The company is not in the business of wowing people with website design. People love the stock price and functionality.

Amazon was the first to come up with the search and filter functionality, Prime, and an actually useful website. Not to forget the fact that their app is basically used on a daily basis by millions and millions of people.

Don’t forget that thin line between functionality and design. Once you have these mock-ups and you do the revisions with your agency or with your designer, look at an implementation. Then marketers start talking about the functionality. Do you need an advanced search and filter or a multi “Add-to-cart”? Optimum7 has built over 700 custom functionalities for platforms like BigCommerce, Shopify, Volusion 3D, Cart, Magento, MEVA, Episerver, and VTEX.

That conversation for functionality, however, needs to be planned at the beginning of the project but executed right after when you have your four mock-ups. And mock-ups unfortunately, most clients and prospects don’t understand this, but mock-up allows you to see that visual element before it’s actually implemented onto the site as HTML and CSS.

eCommerce Web Design that Converts

As previously mentioned, understand the demographic to create the right design. Furthermore, you have your analytics and the source of your traffic. Are they coming in on a mobile device or on the desktop? Design for where the majority of your clients are coming from first.

Many companies will do web mock-ups and then make them responsive for mobile after doing so for desktop. However, if over eighty percent of your traffic is coming from a mobile device, and that’s where you’re getting your conversions, design for mobile-first, and then worry about desktop after.

Implement a full redesign for your eCommerce website if it warrants it. Don’t spend a lot of money and waste time on the design if your conversion rates are great and only if you are truly trying to be a brand. If you’re a brand with a twenty-million USD revenue, you need to compete with people who might be doing fifty to one hundred-million-dollar revenue.

Do not exchange a good design for page speed; always simplify. You don’t need to have different design elements flying around on the home page. Remember simple is good. Take notes from Amazon.


text:
Sparkler Bracelet

Sparkler Bracelet

Grand Pyramid Bracelet

₹13,665 ₹16,076 15%

30 Days Money
Back Guarantee

Lifetime Exchange
& Buyback

100% Certified

  • Quality Packaging
  • Jewellery Certification
  • Free Shipping
  • 30 Days Free Return
  • 100% Refund
  • Lifetime Exchange & Buyback

Product Summary

Customer Testimonials

Opulenzo Diamond

We are diamantaires! While most other jewellers have to buy their diamonds in, we are masters at the art of diamond cutting. Our reputation for cutting the best diamonds dates back to 1980. Our founder Hitendra Shah, over the years, acquired a reputation for being able to bring out the best lustre and vibrancy from even the most irregular rough diamonds. While the industry standard is IJ-SI quality, Opulenzo diamonds are of GH-VS quality or above, cut to absolute perfection. Our relentless dedication and commitment to the craft makes Opulenzo diamonds come to life with a fire and brilliance that is simply unmatched.

A Legend Is Born

Opulenzo was born three generations ago. Its most recent incarnation however, was when co-founders Virat and Parth came online in 2019 with an aim to bring fashionable, curated jewellery to the market. From excellent gold pieces to fabulous natural diamonds being used extensively throughout our collections you will notice our design aesthetic in everything we do.

We focus intensely on quality and range selection alongside a great design ethos and wish to bring the first truly curated jewellery collection online.

Rotate Screen

Your Device

You will enjoy an optimal
browsing experience in
portrait view


text:
Day of Infamy: FDR and Pearl Harbor

Video from CBS Sunday Morning

In the hours following Japan's devastating attack on U.S. military forces in Hawaii, President Franklin D. Roosevelt was remembered for "not losing his cool." David Martin reports on the timeline of FDR's actions between the attack on Pearl Harbor and his address to a joint session of Congress seeking a declaration of war against Japan.

©2020 by Ordinary Life Extraordinary God. Proudly created with


text:
5630 SE 37TH PLACE Ocala, FL
$ 228,900
Property Attributes
  • MLS#OM611069
  • TypePending
  • CountyMARION
  • CityOcala
  • AreaOcala
  • NeighborhoodIndian Pines
  • Zip34480
  • StyleSingle Family Residence
  • Year Built1991
  • Taxes3323
  • Price$ 228,900
  • Bedrooms3
  • Full Bathrooms2
  • Half Bathrooms1
  • Sqr Footage2199
  • Lot Size0.31 Acres
Listing Provided Courtesy Of:
Property Description

Hard to find home in Indian Pines, priced right. Home features formal entry foyer, immense family room with bay window, cathedral ceilings and fireplace. Large kitchen with all appliances, and granite countertops. Large bonus room along with 3 bedrooms. Extra Large master suite with large walking closet. Garage has additional half bath, large storage shed, fenced yard. This home is has screened porch and additional deck. Home has many extras and is a must see.

Price History
11/4/2020 Listed $228,900

General Features

Appliances Dishwasher, Range, Refrigerator
Attached Garage Yes
Construction Materials Stucco
Cooling Central Air
Exterior Features Fenced
Facing Direction North
Flooring Carpet, Tile
Garage Spaces 2
Garage Y/N Yes
Heating Natural Gas
Interior Features Split Bedroom, Vaulted Ceiling(s), Walk-In Closet(s)
Levels One
MLS Area 34480 - Ocala
Property SubType Single Family Residence
Property Type Residential
Roof Shingle
Sewer Septic Tank
Special Listing Conditions None
Status Pending
Subdivision Name INDIAN PINES
Township 15S
Utilities Electricity Connected
Year Built 1991
Zoning R1
Zoning Compatible Yn Yes

Interior Features

Fireplace Y/N Yes
Furnished Y/N Unfurnished
Living Area 2199.00
Total Bedrooms 3

Exterior Features

Building Area Total 3086.00
Foundation Details Slab
Garage Dimensions 23X23
Lot Dimensions 108x125
Lot Size Acres 0.31
Lot Size Square Feet 13500

  • Foreclosure
  • Views
  • Short Sale
  • New Construction
  • Adult 55+
  • Lease To Own
  • No HOA Fees
  • Furnished
  • Master On Main
  • Air Conditioning
  • Seller Finance
  • Green
  • Fixer Upper
  • Horse
  • Golf
  • Fireplace
  • Deck
  • Garage
  • Basement
  • Pool

Property vs Zip Code Average in 34480

AVG $320K
AVG $3,074
AVG 92
Year Built
AVG 2005

Looking for a more comfortable experience?

Download our mobile app for a personalized browsing experience.

Areas We Cover


text:
Free UK. delivery on all orders over £100. We ship internationally.

Long Donegal Merino Cardigan in Rust

Long Donegal Merino Cardigan in Rust

Regular price £215.00 Sale

Please note this shade is currently being made to order - lead time is 3-4 weeks.

Our long Donegal merino cardigan with a deep ribbed hem and cuffs. Shawl collar falling open to the front, no pockets to keep the line clean. Knitted in pure merino wool, spun in Ireland.

  • 100% Merino Wool
  • Spun and dyed in Donegal, Ireland
  • Made in Scotland for Oubas Knitwear
  • Hand wash

S/M: to fit a 6/8/10

Length from side neck to hem is 90 cm

Overarm is 46 cm

Bust and chest (flat at back) is 52 cm

M/L: to fit a 12/14/16

Length 94 cm

Overarm 48 cm

Bust and chest 55 cm

XL: to fit a 16/18/20

Length 98 cm

Overarm 50 cm

Bust and chest 58 cm

We have the M/L in stock, the other sizes are now made to order and will be delivered by 23rd December, if order is placed with us before 6th.


WARC-Identified-Payload-Type: application/text

text: Publication,Date,Time,Page,Text Journals - 13,2020-02-03,12:09:55,145,"The House resumed consideration of the motion of Ms. Freeland (Deputy Prime Minister and Minister of Intergovernmental Affairs), seconded by Mrs. Jordan (Minister of Fisheries, Oceans and the Canadian Coast Guard), - That Bill C-4, An Act to implement the Agreement between Canada, the United States of America and the United Mexican States, be now read a second time and referred to the Standing Committee on International Trade.The debate continued."


text: Publication,Date,Time,Page,Text Journals - 52,2014-02-26,18:30:42,591,"The Speaker ruled that the order for concurrence at report stage of Bill C-461, An Act to amend the Access to Information Act and the Privacy Act (disclosure of information), be discharged and that the Bill be withdrawn, as the sponsor of the Bill, Mr. Rathgeber (Edmonton-St. Albert), indicated that he did not wish to move the motion to concur in the Bill, as amended, at report stage."


text:
Hawkeyes rout Red Hawks under the lights at Kinnick

Hawkeye Headquarters

Iowa defeated Miami (OH) 38-14 in Saturday’s season-opener at Kinnick Stadium.

Senior quarterback Nate Stanley completed 21 of 30 pass attempts for 252 yards and three touchdowns. He passed C.J. Beathard for 8th most passing yards in a career by an Iowa Hawkeye.

Mekhi Sargent led the rushing attack taking 14 carries for 91 yards and a score. He also led the team in receiving hauling in four passes for 65 yards.

Next up for Iowa is another home game as the welcome Rutgers to Kinnick Stadium Saturday, September 7.

Opening week Hawkeye Headquarters coverage is presented by The Robinson Group brokered by eXp Realty.

For more Hawkeye coverage, follow @AdamJRossow and @HawkeyeHQ on Twitter and Facebook — and sign up for our HawkeyeHQ.com pregame and postgame newsletter. All you need is an email address and we’ll send you a newsletter every Friday and Monday during football season.

Copyright 2021 Nexstar Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.


text:
Groups Los Lobos Top groups adventures, activities and tours

Most popular adventures

Groups in Los Lobos

Discounts for bigger groups available. Outdoor adventures and activities handpicked especially for larger groups in Los Lobos, whether for groups of friends, company teams or large families. Great fun guaranteed.

Michal Tyl Photo

We are dedicated outdoor enthusiasts. Let us create your next lifetime outdoor experience.

  • We will handpick the best outdoor activities
  • Book tour dates
  • Find group discounts
  • Give hotel & transport recommendation
Send us custom request

You might also like


text:
• At the beginning of every school year the School Counselor visits each classroom to disuss Bucket Filling.  During these discussions students learn about bucket filling (what it looks like, what it sounds like, and what it feels like), brainstorm ways to be bucket fillers at school and at home, and role play being a bucket filler.  Below are some videos that illustrate bucket filling.

    How Full is Your Bucket? (K-2)

    Browne Elementary School Bucket Filling (3-5)


text:
Show Textbox value to another Textbox

  • As the title says, I have Label2 and Textbox2 on UserForm1. I want the value of this textbox to appear on TextBox1 (same userform) with Label1 showing first.

    Note, there are other values on the textbox1 other than the textbox2 value.

    Below is my code to show values of other functions to TextBox1.

  • Try this


text:
Obsession runs deep in the world of American comics. You can find it in the collector of rare back issues, the cosplayer who crafts a perfect costume re-creation or the fanzine writer who meticulously chronicles their favorite creator’s work. It was a driving force for artist Rocco Versace, who in 1979 killed his writing partner Guy Van and his editor Stan Woodman. All his life Versace was consumed with the desire to become a famous comic book artist, a course which unexpectedly led to double homicide.

Rocco Versace self-portrait from the Heston Guide to Drawing Comics-1978. Colorist Morgan Marie provided original hand colored production art from her collection for this article.

To Versace’s fans, he is a cult figure who created work that was ahead of it’s time. For those who knew him personally his legacy is less clear. Some of his former colleagues support the view offered by the tabloids, that he killed Van and Woodman in a fit of jealousy. Others assert that he was driven to murder by an epic betrayal. Even after almost forty years many still question how the artist’s passion was able to transform into something so sinister. Recently some of his closest colleagues agreed to share their memories in order to set the record straight.

In the summer of 1976, the thirty-eight-year-old Versace had just finished a stint penciling a superhero feature titled “Star-Master” in the pages of Weird Space Tales. The book failed to sell and was promptly canceled. A notorious hothead, he lambasted the series’ editor for the tight plot constraints and cliché writing. He punctuated his criticism by spilling a container of ink on the editor's desk and was promptly fired.

Original art from Weird Space Tales #163 -1976.

From the collection of Cal Hart.

To many people working in the field, comics were simply another gig, but to Versace, they were an underappreciated art form. His life centered around his work, and as a result, he had few friends, no girlfriend, and lived in a run-down apartment in the East Village. Though he had burned the last of his bridges at the major publishing companies he was still unwilling to give up on his dream.

Rocco Versace at his desk in the Heston Comics Offices in 1977. Photograph from the collection of Morgan Marie.

To continue his goal, Versace went knocking on the door of cut-rate publisher Heston Comics. The company's titles could easily be spotted by their cheap paper and poor color registration. Heston editor Stan Woodman knew of Versace’s reputation for fighting with colleagues, but he was also aware of his talent and ability to create work at a prolific rate.
Woodman offered him a job under a strict set of conditions: he would have to take any assignment given, the writer's script must be followed exactly, and most importantly his famous temper must be kept in check. Having nowhere else to go he reluctantly agreed.

For the next six months, he churned out masterful pencils for dozens of hackneyed stories, including several by Guy Van. He disliked the novice writer, believing that Van only got his job because his uncle Marvin Weber was the publisher. It seemed likely that Versace would burn out, but in early 1977 a new staff member joined the company that would have a profound effect on him.

Morgan Marie was a talented and upbeat thirty-three-year-old artist who had previously worked as a penciler and inker in the late 60’s. She then moved onto a burgeoning freelance illustration career, until a family crisis forced her to seek more steady employment. The staff colorist job at Heston had regular hours, allowing her to help her recently widowed sister care for her nephew.

Uncharacteristically, the sullen Versace and cheerful Marie hit it off. Versace was impressed with the care and craft that she put into her coloring. The two would engage in long discussions about their appreciation for the artistry of comics. Their friendship grew outside the office until they spent most of their free time together.

Guy Van in 1977.

Photograph provided by the Heston Archives.

Rocco Versace and Morgan Marie on a trip to the Met in 1977.

From the collection of Morgan Marie.

For the next year, Versace moved from one fill-in assignment to the next. When he would get frustrated by the poor quality stories, Marie would remind him to bide his time and wait for his opportunity. Together they began formulating the idea for their dream project about a character called “The Notion” who could alter reality as he saw fit.

Polaroids of Rocco and Morgan from the collection of Morgan Marie

Finally, in September of 1977, Woodman called Versace, Van, and inker Charlie Ebert into his office and informed them that they would be the new creative team on the struggling series Roscoe Dolittle. The long-running title featured a tough but kind woodsman reminiscent of Daniel Boone. After a year of toiling on throwaway back-up stories, Versace thought he was entitled to be given a better assignment.

Roscoe Dolittle as he was drawn by Silver Age artist Jerry Gee. Promotional material from the Heston Archives.

“I remember him just sitting there staring daggers at Woodman,” recounts Ebert. “Rocco did this thing where he breathed really loudly through his nose, and it always intensified when he was upset. Well, you could probably hear him breathing down the hall at that point!”

He was ready to quit altogether, but Marie convinced him that doing a good job on the series would impress Woodman enough to give him the assignment he wanted. The following Friday, he met with the new creative team at a local bar.

“(Guy) was drunk as a skunk, and just kept talking about how he was going to move to L.A. to become a screenwriter,” said Ebert. Versace then made a proposal to the inebriated writer. He would pencil and plot out the stories, then hand them over to Van with notes, who would fill in the dialogue. It was a fairly routine arrangement at many publishers, but much different from the strictly segregated assignments common at Heston. Van readily agreed. “After that, Rocco just got up, threw down money for the bill, and left. I guess he got what he came for,” said Ebert.

Panel from Roscoe Dolittle #125.

Color guide from the collection of Morgan Marie.

The next Monday Versace returned to the office with twelve complete pages of a new story and deposited them on the desk of a surprised Van. “I’m not sure he even remembered making the agreement,” said  Ebert. “Still, he seemed happy he didn’t have to do the work!”

Cover of Roscoe Dolittle #120, Versace's first issue as series artist.

 Color guide from the collection of Morgan Marie. The codes written on these guides were used to let the color separators know exactly which colors to use.

The cover of the issue featured the title “Apocalypse Punks from the Future!” and sported bold colors from Marie. The insides were similarly sensational and featured Roscoe stumbling upon a group of time-traveling mutants.

“It was pretty crazy!” said Ebert. “Rocco lived above this venue that had a lot of punk shows in the Village and they would always shout stuff at him. It made sense that they became his villains.”

Over the course of the next few issues, Roscoe battled demons, robots, a shadowy version of himself, and the returned Apocalypse Punks. Versace’s notes became more detailed to the point where he eventually started to loosely pencil in the dialogue. He snidely came up with the by-line “brought to you by Raging Rocco Versace and Genius Guy Van” in order to obscure the exact division of duties.

Heston Comics Bullpen 1977. From the Heston Archives.

While Marie provided inventive colors for the series her name was left off of the credits, as was often the case with colorists. She also regularly discussed story ideas with Versace, many of which he incorporated. In one of the classic issues of the run, Roscoe gains the ability to alter reality much like “The Notion”, and magically transforms an armadillo into a creature that can walk upright and talk. The new character nick-named Army by Marie became Roscoe’s regular traveling companion. Versace insisted that her name be added to the credits but Van strongly protested. He quickly backed off however when the temperamental artist threatened to not write the next issue.

Spread from Roscoe Dolittle #134.

Color guide from the collection of Morgan Marie.

According to staff letterer Julie Smith, Marie was thrilled with the work she was doing on the book. “Morgan would rush through the rest of her assignments,  then spend hours making sure every page of Roscoe was perfect,” she said.

Sales of the title started to tick upward. At the same time, it began receiving positive reviews in the pages of comic fanzines like the Nostalgia Notebook, which praised “Rocco’s superb art” and (what they believed were) “Guy’s endlessly inventive plot lines.”  Versace reveled in the praise but bristled every time someone complimented Van. “I knew it must have driven him crazy to not get credit for his own ideas,” said Ebert. “But he was so pleased with the book's success, he didn’t let it get to him.”

Nostalgia Notebook #33 one of the many fanzines that praised Roscoe Dolittle.

In the fall of 1978, Roscoe Dolittle became Heston’s best selling title. Emboldened by their success, Versace and Marie decided to pitch “The Notion” to Woodman. They began tirelessly working on the story in between their other assignments.

These two items hung above Versace's desk at Heston: a clipped house ad for Roscoe Dolittle and his concept drawing for "The Notion".

From the collection of Morgan Marie.

The weekend before Halloween, Heston staffers threw a costume party at a local bar. Marie convinced the anti-social penciler that they should take a break from their work and attend. She crafted an Apocalypse Punk costume for herself and bought a Daniel Boone costume for him. Versace spent the party drinking at the bar while Van used it as an opportunity to schmooze with Woodman. The editor congratulated the young writer on his success and asked if he’d be up to start writing scripts for some licensed movie adaptations. Van was ecstatic as he thought this was the next best thing to being a screenwriter. As the night went on Van continued to brag about his writing prowess. To the amazement of Ebert, he took full credit for the success of Roscoe Dolittle.

“Guy started telling Woodman these crazy stories about having to go to Rocco’s apartment and beg him to finish the pencils on time,” said  Ebert. “He took credit for every story detail, all the layout concepts, everything! I’m surprised he didn’t claim he inked the damn book as well!”

Heston Staffers at a costume party in 1978. Featured are Rocco Versace (Roscoe Dolittle), Morgan Marie (Apocalypse Punk), Guy Van (vampire), Charlie Ebert (costume), Julie Smith (witch), and Jonathan Smolder (mummy). Polaroids from the collection of Morgan Marie.

As the party wore down, Ebert approached Versace and Marie and told them about the conversation. “I tried to frame it by telling Rocco this probably meant Guy would be moving onto other books, ” said Ebert. “ I should have just kept my big mouth shut.”

The next Monday Versace arrived early to the offices and waited in the hall. When Van stepped out of the elevator Versace slammed him against the wall spilling his coffee. The two began to loudly yell at each other and a number of staffers rushed out to see what all the commotion was about. They had to be physically separated, and Woodman ordered Versace into his office. “I remember the smirk on Guy’s face as Rocco slunk away. He was like some high school bully who knew he got away with something,” said Julie Smith.

Panel from Roscoe Dolittle #139.

Color guide from the collection of Morgan Marie.

Despite the closed doors, the Heston staffers could hear every word of the heated conversation. Versace told Woodman the truth about his role as writer and demanded that he fire Van. In response, the annoyed editor demanded he apologize. Woodman reminded Versace that Van was the nephew of the publisher and “a hell of a lot more important around here than you.”

Charlie Ebert and Rocco Versace at the Heston offices in 1978. Aside from Marie, Ebert was Versace's closest friend at Heston.

From the collection of Morgan Marie.

“That was just too much for old Rocco,” said Ebert. “He couldn’t stand that all his hard work meant nothing, and that Guy was going to skate right past him simply because of who he was related to.” Versace slammed his fist down on Woodman’s desk which caused his coffee mug to fall and shatter. Woodman fired him on the spot.

When Marie arrived, she attempted to calm Versace down. Ignoring her, he headed for the flat files that housed the production artwork and began pulling out his original art. “Stan rushed over and slammed the file shut,” said Smith. “When he told Rocco the pages belonged to Heston I thought he was going to lose it, but instead he just stared at him for a second, then turned and left.”

Marie glanced around the room of shocked staffers, before settling her gaze on Van who was waving goodbye to Versace. “She calmly walked over to him and slapped him before heading after Rocco,” said Smith. “Guy certainly deserved it.”

Rocco and Morgan at the Heston Offices in 1978. From the collection of Morgan Marie.

The next month, the final issue of Roscoe Dolittle featuring Versace’s contributions hit the newsstands. It was bizarre even by his standards and contained an extended conversation between Roscoe and Army about the possibility of them being characters in a story. Though considered odd at the time, the issue became a cult classic. According to alternative comic artist Cal Hart, it had a profound influence on many creators of his generation. “It really pulled you out of the fantasy and made you think about the medium. I remember being kind of freaked out by it as a kid” said Cal.

Spread from Roscoe Dolittle #142 1978.

Color guide from the collection of Morgan Marie.

After that, Van took over as writer while the art duties fell to Heston Comics stalwart Jonathan Smolder. Missing the brazen artwork and eccentric writing that had defined the series the next two issues sold poorly.

Ebert and Marie attempted to reach out to Versace but he repeatedly pushed them away, calling them traitors for continuing to work at Heston. With his comics career over, Versace had nowhere to channel the obsession which had always fueled him. He focused all of his energy on Van  and began writing letters to fanzines denouncing him as a “talentless hack.” Ebert and Marie were exasperated but assumed Versace would eventually calm down. They were not prepared for what happened next.

Panel from Roscoe Dolittle #138.

The Apocalypse Punks always seemed to get the upper hand on Roscoe.

Color Guide from the collection of Morgan Marie

Around 2:30 PM on February 13, 1979, Versace left his apartment dressed in the Daniel Boone costume he had worn to the Halloween party. Notable additions to the outfit were a Remington 870 shotgun slung over his shoulder and a medium sized leather satchel at his waist. The first people he encountered were musicians from the punk band Toilet Duck who were waiting in front of the club below. Seeing his ridiculous getup, they began to heckle him. Without hesitation, Versace turned and bludgeoned singer Brian Bender with the butt of his gun fracturing his skull. After fleeing the scene, he was not seen again until he burst into the Heston offices thirty minutes later. The startled staff immediately recognized him. Versace moved slowly towards Van’s desk and told him to get up. He then walked over to Woodman’s door and smashed the glass out of the window. He instructed Woodman and Van to remove all of his Roscoe Dolittle artwork from the flat files and placed them in his leather satchel. Versace pulled out one piece of paper and deposited it on Woodman’s desk before backing away from the frightened pair.

Guy Van at the Heston offices-1978

From the collection of Morgan Marie.

Before he left, he turned towards Van with a smile and said: “Hey Guy, let’s see you take credit for this”. He then shot the writer in the chest. Woodman ran towards the gunman in an attempt to disarm him, but Versace fired first, hitting him in the stomach. According to several staffers, his expression then became distraught. As everyone screamed, the panicked gunman fled down the hallway. Van died instantly. Woodman would survive for another few hours before dying in the hospital.

The tabloids picked up the story and ran with it, while the police performed an extensive search and investigation. All that remained in Versace’s apartment were pages from his pitch “The Notion”. The single sheet of paper he had left on Woodman’s desk was from the same comic. It contained the ominous line: “DENY ME AT YOUR OWN PERIL!”

Page from Rocco and Morgan's proposed comic "The Notion". Color Guide from the collection of Morgan Marie.

Marie attended the funerals but then left the comic book industry indefinitely. She returned to her freelance career, eventually becoming a highly sought-after illustrator.

Though in the past Marie had refused all requests to be interviewed, she made it known through Ebert that she had relics from her time at Heston she would like to share. The photographs, original drawings, and hand-colored production art presented in this article are a small fraction of her collection.

Rocco and Morgan enjoying a fall day in the park. One of Morgan's fondest memories of their friendship.

From the collection of Morgan Marie.

“I’m getting old,” Marie said laughing as she puffed away on a cigarette. “I figure if I die, this stuff will probably just be dumped in the trash by my nephews.” While Marie was unwilling to sit down for a full interview, she was still proud of the work she had done and thought it deserved to be shared. “It’s funny,” she said “I was an illustrator a lot longer than I worked in comics, and was a great deal more successful at it, but the only people who come asking questions want to know about Rocco. What is it about those old books that make you people so damned obsessive?”

Marie requested that all of the artwork be donated to “whoever the hell would want this stuff” after it had been scanned for the article. “It just makes me sad to look at it anymore,” she said. “I think about all the work and thought that went into it that was completely wiped out by the selfishness and vanity of that man. Have you ever had a friend that completely let you down?”

Some of the many photographs that Morgan Marie took during her time at Heston Comics in the late 70's.

As for Versace, he was never heard from again. The police gave up searching for him as the headlines went away. Rumors persisted for years that he was creating comics under assumed names, and even submitting pages of “The Notion” to publishers anonymously. In the decade after the murders, his work was rarely discussed. Van’s uncle took every opportunity to tout the writer’s genius but never spoke his murderer’s name.

In recent years, a new generation has begun to embrace Versace’s work. Stories about his role as the writer of Roscoe Dolittle were spread by former Heston staffers. The tale of Versace reclaiming original artwork from his publisher had a romantic quality for some artists. Some even consider him to be a symbol of creators’ rights. To Charlie Ebert, this claim seems outlandish and insulting. “I don’t think Rocco cared about anyone’s rights but his own,” said Ebert. “It’s not like he killed Guy for some cause, he killed him because he hated him.”

Panel from Roscoe Dolittle #142 1978.

Color guide from the collection of Morgan Marie.

Most people assumed that Versace was living in seclusion somewhere off the grid. “I don’t know,” mused Ebert in response to this suggestion. “Rocco was a real New York City guy, I really can’t imagine him living out in the sticks somewhere. If he didn’t off himself, I’ll bet he’s still hanging around. In a way, that would almost be worse than death for Rocco, to still be here so close to where he almost made it, yet completely anonymous.” Ebert paused for a moment and then offered a final thought.  “If he is alive, I’ll bet he’s sitting on a stack of pages ten miles high.”


text:
128th Canton Fair Online, China PACO Power

Canton Fair Online

  • It’s really the histroy we are witnessing,
  • As you see it’s coming the second online Canton Fair in this October, 2020. Online Fair will become the main-stream in the near future.
  • The 128th Canton Fair Online would be on the stage during October 15 and October 24.
  • We PACO will still provide with round-the-clock service on promoting and presenting what we can offer for your project needs.
  • Let’s chat beyond the space and time in the LIVE meeting !
  • More detail will be available soon.

Hope you and your family are doing well and stay health! And thanks for your support!

Post time: Oct-08-2020
WhatsApp Online Chat !


text:
Pan American Health Organization

Country Report: Colombia

Colombia is located in the northwest of South America, and borders Brazil, Ecuador, Panama, Peru, and Venezuela. It is divided into 32 departments, a capital district, 1,121 municipalities, and indigenous territories.

Population growth in the period 1990-2016 was 42.0%, during which time the population structure became regressive and older. By 2015, the population reached 48,747,708, with 79% living in urban areas.

Life expectancy at birth is 74.4 years.

Also between 1990 and 2015, the basic health indicators reflected remarkable improvement overall.

  • The National Pharmaceutical Policy seeks to safeguard the quality of medicinal drugs and people’s access to them.
  • This policy provides for price regulation instruments based on international benchmarks, the registration of biosimilar products, and the strengthening of national capacity, as well as mechanisms for incorporating marketing authorization procedures.
  • The policy proposes 10 strategies related to the accessibility, timeliness, quality, and rational use of medicines, regardless of individual ability to pay.
  • Cross-cutting strategies include making available reliable, timely, and public data on access to drugs, drug prices, utilization, and quality; the establishment of an effective, efficient, and coherent institutional system; and improvement of the availability and competences of the pharmaceutical sector workforce.
  • The National Food and Drug Surveillance Institute (INVIMA) has been certified as a National Regulatory Authority for Regional Reference on medicines and biologics.
  • The country has also established requirements for bioavailability and bioequivalence studies of medicines.
  • Another highlight was the development of price regulation and market regulation instruments based on international benchmarks, as noted above.

Figure 1. Distribution of the population by age and sex, Colombia, 1990 and 2015

Proportional mortality (% of all deaths, all ages, both sexes), 2013

Source: Pan American Health Organization. Health Information Platform (PHIP).

Population (millions)
  • Population (millions)
  • Gross national income by purchasing power parity (ppp, US$ per capita)
  • Human Development Index
  • Mean Years of Schooling
  • Improved drinking-water source coverage (%)
  • Improved sanitation coverage (%)
  • Life expectancy at birth (years)
  • Infant mortality (per 1,000 live births)
  • Maternal mortality (per 100,000 live births)
  • TB incidence (per 100,000 inhabitants)
  • TB mortality (per 100,000 inhabitants)
  • Measles immunization coverage (%)
  • Births attended by trained personnel (%)

Source: UN Population and Statistics Divisions, 1990; PAHO Health Information Platform (PHIP), 2013, 2014, and 2015.

  • In 2015, income inequality was high, as reflected by a Gini coefficient of 0.522; 27.8% of the population lived below the poverty line. The introduction of wage reforms contributed to a reduction in unemployment down to 8.9% in 2015.
  • The El Nino and La Nina climate phenomena had both direct (deaths and injuries) and indirect impacts on the health of the population, negatively affecting determinants such as poverty, food insecurity, and access to safe water.
  • In 2015, 91.2% of the population had access to improved sources of drinking water and 81.1% to improved sanitation, although coverage in rural areas and among the indigenous population is low.
  • Violence and public insecurity constitute an important problem, compounded by the impact of more than five decades of armed conflict with guerrilla forces. This has spawned phenomena such as organized crime, forced displacement, and the confinement of an estimated 8 million people.
  • In 2013, homicide was the second leading external cause of death in men (57.38 deaths per 100,000 population), and the tenth leading cause in women (5.05 per 100,000 population).
  • Emigration is a significant phenomenon, especially to the United States (34.6%), Spain (23.1%), Venezuela (20.0%), and Ecuador (3.1%), with Colombian nationals representing 98% of all immigrants in this latter country.
  • Vulnerability and inequity in the population are exacerbated by the limited presence of institutions in areas where indigenous, rural, and Afro.Colombian populations reside. Further contributing factors are illegal farming and mining, as well as sparse settlement in isolated regions.
  • In 2014, the maternal mortality rate was 53 deaths per 100,000 live births. However, the rate was 2.8 times higher in departments in the highest poverty quintile. Up to 60% of maternal deaths were recorded in the poorest and most illiterate 50% of the population; 18% of the total was in mothers between the ages of 10 and 19; 24% in the indigenous and Afro-Colombian populations; and 30% in mothers with a primary education or less.
  • In 2013, the infant mortality rate was 17.25 deaths per 1,000 live births. This rate is higher in the poorer sectors of society and among mothers with a low educational level. Infant mortality accounts for 82% of deaths of children under 5 (a rate of 14.1 per 10,000); leading causes include prematurity, congenital malformations, respiratory disorders, neonatal bacterial sepsis, infections of the respiratory and digestive systems, and malnutrition.
  • In 2014, the country was declared free of measles, rubella, and congenital rubella syndrome. In 2015, MMR vaccine coverage was 93.9% for the first dose and 87.5% for the second dose.
  • Between 2005 and 2013, 29.9% of all deaths were caused by diseases of the circulatory system.
  • The most prevalent neoplasms included stomach cancer (16.5% of all cancers in men) and breast cancer (12.6% of all cancers in women).
  • Malaria is endemic in Colombia. In 2015, there were 52,416 recorded cases of malaria and 1,018 cases of Chagas disease (996 chronic and 22 acute, with a case-fatality rate of 0.07%).
  • Since 2010, trachoma has been considered endemic, with rates of up to 21% to 26% along the border with Brazil.
  • Dengue is a reemerging problem; outbreaks of the severe form are on the rise, with a case-fatality rate of 6.3% in 2014.
  • In 2015, the incidence of chikungunya was 1,359 cases per 100,000 population, with a case-fatality rate of 0.02%. The Zika virus (ZIKV) epidemic ended in mid-2016 with 8,826 confirmed cases, 91,640 clinically suspected cases, and 21 confirmed cases of ZIKV-associated microcephaly.
  • In 2014, the rate of HIV infection was 11.6 cases per 10,000 population, with 0.45% of 15-to-49-year-olds affected. The epidemic is concentrated in large cities, which account for 86% of reported cases.
  • Between 2005 and 2013, there were 417 deaths from malnutrition in children under 5 per year on average. The problem is greater in predominantly indigenous populations living below the poverty line.
  • In 2016, 2.7% of the population was disabled; this percentage rose to 45.5% in people older than 60.
  • The Statutory Health Law (2015) enshrined the right to health care within the national health system, recognizing it as a basic social right.
  • In 2014, national health expenditure accounted for 7.2% of Gross Domestic Product (GDP) (5.4% public and 1.8% private), while out-of-pocket spending accounted for 15.4% of total expenditure.
  • Greater public and private expenditure is required to meet the growing cost of new health technologies, progressive population aging, and increasing insurance coverage. Increasing judicialization of health, i.e., the practice of litigating for the protection of basic health rights, is contributing to these rising costs.
  • The Colombian health system is made up of a social security sector and a private sector. The backbone of the system is the General Social Security Health System, which has two regimes, contributory and subsidized.
  • Membership in the General Social Security Health System is compulsory and is handled through public or private health promoting agencies (EPSs). The EPSs turn over the funds from premium payments to the Solidarity and Guarantee Fund (FOSYGA).
  • As of 2015, health system membership was 97.6%.
  • In 2012, the ratio of health professionals per 10,000 population was 17.7 for physicians, 10.3 for nurses, and 8.3 for dentists.
  • The country has 55 medical schools, graduating an average of 5,000 physicians annually, and 65 nursing programs, graduating an average of 3,600 nurses annually.
  • As of 2016, 242 public health institutions were registered to use telemedicine services and improve the electronic connection between clinical services, thus providing better functional access to health care. The Comprehensive Social Protection Information System (SISPRO) provides a mechanism for obtaining and consolidating information on health, occupational safety, and social welfare.
  • Since 2013, Colombia has had a National Disability and Social Inclusion Policy in place, aimed at ensuring more effective implementation of action related to disability.
  • In 2014, Law No. 1733 was enacted, regulating palliative care services for the integrated management of patients with terminal, chronic, degenerative, and irreversible illnesses at any stage of any disease having a major impact on quality of life.
  • In 2016, the Comprehensive Health Care Policy (PAIS) was introduced, making the individual, family, and society, rather than health providers and insurers, the center of health action. The formulation of this policy and of the Comprehensive Health Care Model (MIAS) represent a strategic advance by the health system in its commitment to ensuring that citizens have access to health services. It is the operative component of the PAIS.
  • A family and community health and medicine approach, designed to build competencies in the health workforce, is being developed within the framework of the MIAS.
  • Both the PAIS and MIAS are meant to improve quality, sustainability, and equity in health. They provide a framework of actions ranging from health promotion and disease prevention to treatment, rehabilitation, and social reintegration at all stages of life, as close as possible to citizens’ daily lives.
  • The objectives of the 10-Year Public Health Plan 2012-21 (PDSP) are to attain equity in health, positively influence the social determinants of health, and mitigate the impact of the burden of disease.
  • In 2015, the Government committed to reducing premature mortality from cardiovascular disease, diabetes, cancer, and chronic respiratory diseases by 8% in the population aged 30 to 70.
  • The 10-year Plan for Cancer Control 2012-2021 seeks to reduce cancer mortality by 30% in this period, integrating the control of risk factors such as smoking, sedentary lifestyle, high sugar intake, and obesity.
Regional Office for the Americas of the World Health Organization
525 Twenty-third Street, N.W., Washington, D.C. 20037, United States of America