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Interview with the FPWR Research Team [2019 CONFERENCE VIDEO]

In this 57- minute video, FPWR Executive Director Susan Hedstrom moderates as the FPWR research team provides an update on PWS research, achievements to date, and what we are doing to develop treatments for our loved ones with PWS. This session includes Q and A with conference attendees. Panelists include research team members Theresa Strong, Nathalie Kayadjanian, and Lauren Schwartz Roth and FPWR CEO John Walter. Click below to watch the video, or scroll down to read a transcript of the session.

Q: FPWR has invested more than $12 million into PWS research. Much of this has been through our grants program. Can you give us an example of how the grant program is yielding some results for us?

Theresa Strong:

The grants program has been our ‘bread and butter’ since we began. This is a competitive grant program where twice a year, we ask the scientific community to bring us their best ideas. Scientists are thinking about these things all the time and they're in a really good position to understand how to move the field forward. We have scientists review and parents review, so that we get the best science that's also relevant to families, and support that. Some of you have participated in the review process. A very broad portfolio of projects  come out of the grant program, and they were reflected in the day and a half of scientific presentations at this year’s PWS Research Symposium. I would say probably 80 to 90% of what was presented at the Research Symposium was funded by FPWR.

The grant program includes everything from really understanding the genetics of PWS to clinical trials all the way through and through. A few specific examples... If you donated in 2011 or 2012, your funds went towards the first clinical trial of diazoxide, the DCCR molecule, and it was the success of that trial that allowed a pharmaceutical company to come in and pick that up and now, they're now funding the phase 3 DESTINY-PWS trial. If you provided funding in the 2013 range, some of the studies that we supported then were the genetic therapy studies, which have shown promise in mouse models and are advancing towards clinical trials. You have funded new collaborations between some of our investigators. All of the studies, for example, that use dental pulp STEM cells derived from teeth were FPWR funded studies, and those have really gone a long way to helping us understand the molecular changes between PWS and typically developing individuals.

Q: The first gene therapies for rare disorders have recently been approved in just the past couple of years. These therapies have cured a genetic cause of blindness as well as treated spinal muscular atrophy, which is the leading genetic cause of infant mortality. What are the opportunities for developing a gene therapy treatment for PWS?

So we talked a fair bit about this yesterday. PWS is complicated. So those specific examples, spinal muscular atrophy and blindness, are caused by a single gene. You just replace the protein. It's not easy, but it's sort of a simple problem. PWS is much more complicated because we're dealing with several genes and several RNAs. I believe the gene activation approach, where we're trying to turn on the existing chromosome 15 material that is derived from mom's chromosome  in every individual with PWS but silenced, is a good way to progress for us. With the genetics therapy workshop that we just had, we will put together a road map to try to move that work forward as quickly as we can.

Q:  It has taken several years, but the Global Prader-Willi Syndrome Registry now has nearly 2000 participants enrolled. Why is it so important for people to participate in the Registry?

As we've tried to emphasize, in order for us to understand the incidence of all of the symptoms that occur in PWS and the natural course of the disease we need to have long-term natural history data. Its critical for us to be able to see if any of these new interventions are actually impacting the end result in our kids. We've also used the Registry in collaboration with LEVO therapeutics to develop a new anxiety measure that is now being used in clinical trials. We continue to add new surveys which is why it's so important for you to come back to the registry and continue to complete, and update surveys. If you see in the clinical trials alert that we have a new survey, your participation is really important. Your participation is supporting the clinical trials that are ongoing, and also to helping us understand what problems your kids are having, so that we can be proactive in trying to help the clinicians  study areas that appear to be popping up or develop standards of care that will help our kids have the best outcome possible.

Q: FPWR has recently begun investing in small pharmaceutical companies in the beginning stages of drug development. Could you tell us a little bit, John, about the strategy and how it will accelerate our work towards treatments for PWS?

John Walter:

For a long time, our Foundation has been funding bright ideas in labs. And we've come a long way! Now we have several active clinical trials recruiting patients for potential treatments. So the idea with venture philanthropy is to bridge a bright idea in a lab and bring it forward to a clinical trial. This process can take a fair bit of time and we want to speed it up. We've attracted a lot of interest in the PWS space and we now have many companies coming to us to tap into our expertise. The thought here is to look at the entire continuum of drug development, from preclinical trial work to phase one, phase two, and phase three trials. And where can the foundation help financially, and intellectually, to help take some of these early companies that are looking at our space and potentially move  forward trials and invest in them. Invest in them financially and lend our name to the fact that our scientific advisory board has reviewed the science there. Our investment committee has looked at the companies and the structures of those companies and said, this is a good bet. And the goal there really is to help bring larger dollars to bear for these companies and accelerate their work.

Our board just approved this approach to investing. And this summer  we invested in two companies. The first one we have talked about, it's a company called Inversago. This company has a reformulated compound that had some issues earlier but they've reformulated so that it doesn't cross the blood brain barrier. It targets the endocannabinoid area of the brain, and targets a number of things, such as hyperphagia and behavior, like many of these other trials that are going on. We had invested them once already through our grant program, then they came back to us again, and now we have invested in them again.

The other company, interestingly enough, has been established based on research FPWR originally funded at the Hebrew University. They identified a molecule that showed propensity for enhancing bone strength and bone density. They have intellectual property has been licensed to a company called Beryl Therapeutics. They approached us about joining an early friends and family round, to try and move that science forward. We invested $150,000 in that company, which represents 10% of that friends and family round. The goal is help them get the work done to see if there can be the opportunity to prove efficacy.

Q: So clearly a lot of work has, has gone into play in the last even just five years. We went from having no clinical trials to now having three that are actively or five actively recruiting drug trials and more coming. So what do you think has been one of the most significant factors in bringing clinical trials to PWS? And maybe you could talk a little bit about FPWRs role in that.

Nathalie Kayadjanian:

I think one important thing is that we have developed a research ready community. Often companies are interested in rare diseases as a ‘proof of concept, before then going on to more common indications, such as obesity. Companies are looking at rare diseases, like PWS, and they not only want to know if the science suggests their drug may be helpful in that disorder, but also what tools are available to help them and how strong is the patient community. They want to know how we can help identify patients and whether there is a patient registry. (Our registry currently has nearly 2,000 participants!) That's one of the first things that they, they ask. So all these tools are really important also to attract these companies.

I can add that we also are really proactive in engaging the FDA. We are involved in larger efforts by the rare disease and other disease communities that keep us at the forefront of how do you effectively engage the FDA, how do you educate the FDA about the needs of the community? FPWR’s a member of the clinical trials transformation initiative which is a public-private partnership between the FDA and Duke University that is charged with making clinical trials more efficient. Also, Jessica Bohonowych and I have both been involved in some projects through that effort, how to best engage patient groups. I was in a project on using mobile technology in clinical trials and it's an opportunity that is a partnership of academic groups, many of the large pharmaceutical companies and patient groups so it's a great opportunity for networking. I'm also on the patient engagement collaborative at the FDA, which is a three year appointment. It's a fantastic group of advocates that work towards improving communication between the FDA and the patient community. And just being a part of that I go to DC twice a year and we have i-person meetings and it's an opportunity to learn about the FDA. I've been engaging the FDA for many years now and it's kind of a Behemoth so even knowing who you should be talking to takes a few years to figure out. So just having that direct contact and someone at the FDA that you can pick up the phone and ask ‘how do I navigate this’ is just fantastic. So I think being proactive and being part of these groups is really important to make sure that we're doing everything we can to be advancing the efforts of our community.

I'd add one other thing. One of the things that FPWR does really well is proactively connecting the dots. So being aware of what companies are doing, that might have overlap into the PWS space. And I'll give you a specific example of that. This summer I was up in Boston and was talking to someone and they mentioned to me that there was this company that they had come across that was developing a blood thinner, so a competitive product for products like perhaps Warfarin or Eliquis that you might be familiar with. This blood thinner will be a second generation that has less of the side effects. And I had an early conversation with the company and said, look, are you aware of the, of the thrombosis issues that exist in PWS? Would you have any interest in doing that? And so of course after that conversation was over, I quickly knew I needed to connect them with Theresa to have a more in depth scientific discussion to talk specifically about the underlying issues of thrombosis and PWS. But the CEO of that company came to the consortium meeting this Wednesday to try and learn more about what we're doing and what kind of resources we had to help them, and potentially they might have an interest looking at PWS and addressing those thrombotic issues.

Q: So our next question is going to go out to our mental health expert. Lauren, we know that there are many people who have PWS who struggle with mental health. What are we doing to understand why our loved ones are at a higher risk and what are we doing to help them?

Dr. Lauren Schwartz:

One of the things that I’ve been interested in for many years, given all of the challenges that our kids can have, is really understanding some of the early signs and predictors of mental health challenges. And if we can understand the early signs and symptoms, we might be able to do more to intervene earlier on. Generally, in mental health, if you diagnose and treat early, you have a much better outcome and you might even be able to prevent some more severe symptoms. So that's something I'm very interested in.

We have funded several grants over the last few years that have been looking at sensory, cognitive and social challenges to see if that may help us understand the trajectory towards mental health problems. We're also just funded an MRI study by Stuart Einfeld and Lauren Rice at the University of Sydney who do lots of great research. They're also doing the mindfulness study. And they're interested in looking at GABA in the brains of people with Prader-Willi. And GABA is a chemical in the brain that is linked to emotional challenges in several different conditions prior to really autism and some other conditions as well. And people with PWS tend to have lower levels of this important brain chemical. So they are looking at the brains of people with Prader-Willi and they're going to be giving them a medication that is supposed to change levels of GABA and they'll see if this can help sort of normalize those levels in the brain. And if that happens, then they'll go to the next step to see if doing a clinical trial in that area would be helpful. So I think there's a lot of interesting things going on in that area.

We're also starting to look at ways of talking with families and Prader-Willi behavior experts about their experiences struggling with mental health challenges. And again, what are some of the early signs and symptoms that parents and caregivers recognize? What kinds of treatments have been helpful so that we can create a framework to help parents prepare and be informed of these things if they do become an issue down the road.

We also have two trials going on right now that are recruiting participants. One is for guanfacine, to see if it's helpful for aggression and impulsivity and other behaviors. Another study is taking place at the University of Sydney on mindfulness, looking at this very specific intervention for people with intellectual disability in Prader-Willi, to see if they can learn to use these techniques to control their anger and other symptoms as well. So there are things going on right now that you could possibly participate in that could be helpful for your children.

There's also another study that just started. Dr. Jan Forrester who is a psychiatrist whose worked in Prader-Willi for decades. She's a real expert in the area, has become very interested in family stress for people who are parenting a child with Prader-Willi. And in particular she feels like the dads have been really neglected. And so she has developed a study to look at a very specific intervention called ACT, which is acceptance and commitment therapy. It's kind of a version of cognitive behavioral therapy and mindfulness for dads and who have an adolescent with Prader-Willi. And it's also a virtual online kind of Skype intervention, it's four sessions. And so she's recruiting currently for that study, and we're really excited to be having some focus on the dads.

If you want more information, if you go to we have a menu items called clinical trials. All of the trials are listed there, both the drug trials as well as intervention trials. If you scroll through, you're going to see a nice list of opportunities that are enrolling patients currently.

Q: This final question goes to every member on our team before we go to the audience. What is the next three to five years look like in research?

Busy! If the last three to five years is any indication, the next 3-5 years will absolutely be busy and I hope transformational! I think there's a lot of things on the horizon that really have promise in the next few years. I mean all the way from babies, right? So newborn screening: we expect in five years to be advancing to the point that we're diagnosing every baby at birth and getting them right into a doctor. If you diagnose every baby at birth, you can get them right on growth hormone and give them the best possible start. These drugs that are in clinical trials now I think will, I mean in my wonderful imagining of the world, we'll have many options with new drugs that are approved. And so we'll be able to find the drug that works best for our child and the particular ‘brand’ of PWS that they have. And then we'll be moving forward and hopefully making fantastic advances in getting at the root cause of PWS and maybe, you know, moving genetic therapies ahead. So that's a couple of things.

We are developing a pre-clinical network to improve mouse models which are used in preclinical stages. And why do we do this? Because we want to de-risk drug development. This will improve how we do research and will improve our ability to develop drugs, specific drugs for PWS.  It will be advantageous to have good cellular and animal models where we can directly test drugs against all the major symptoms of PWS.

Well it's my hope that within the next three to five years we will have some treatments that have been studied and are effective for the mental health challenges that our children experience, both medication as well as some non-medication approaches and also some interventions out there that are accessible to families to help reduce stress so that we can have renewed resources to keep going, to take care of our children and, keep trying to find more treatments.

I like to really boil things down in ways that we can understand them. The way that I look at what we're doing now and, and where we are is really straight forward. Our research programs are really doing two things: We're looking for solutions now. How can we bring forward therapeutics to address some of the hallmark symptoms of Prader-Willi syndrome? So hyperphagia, behavior, etcetera. And the good news is that those are being addressed. So within the next three to five years, I think we will have at least one, possibly two, and hopefully three approved drugs for hyperphagia and behavior or various aspects of behavior. We all know that the issue of Prader-Willi syndrome is a spectrum disorder. So to have the option of having several drugs that address the same symptom is wonderful.

The other piece of this is the hope for the future and the hope for the future which could be measures in the area of genetics for prior Willi syndrome. In the next three to five years, I'm optimistic that we will begin to see if we can put forward work that will allow us to potentially do partially curative treatments in the area of genetics or Prader-Willi syndrome.  If we don't try, it won’t happen. If you listen to Stormy Chamberlain and Jim Resnick talk about some of the things they're doing, there are opportunities there where we can do proof of concept. And the only thing that stands between us and doing that is the dollars to fund the work. So I think a big part of this is really when you go back to your communities, talk to them and your friends and families, and we're making amazing progress. We couldn't do it without you. And we're not going to make these achievements in that three to five window without more help from you.

Questions From the Audience

Participant: I have a specific question on the guanfacine trial. I'm just curious, what's the purpose of the trial right now? We can go see our doctor, we can get it prescribed already. What would be the benefits of going through their study rather than just going directly through our doctor?

The purpose of the study is to understand in a controlled setting how well guanfacine works. So we all hear, ‘oh, this works.’ It's the same thing that we do with supplements, right? One family feels like it works, one family feels like it doesn't. But if you do a trial and you have the same physician looking across all of the patients, A) you get a real handle on what dose and how you should administer it and B) you get a real handle on the safety concerns and C) what percent of kids are going to find it effective. And if there's certain genetic subtypes that are more effective than the others, or other characteristics that are going to distinguish responders from non-responders, you can pick that up. So a study like this makes it more efficient to actually know what to do for any individual child.

Just going to add that a lot of times these medications are tried and we feel like the individual seems better, but this was going on and this was going on, so we're not really sure whether it was the medication or something else. In a trial where they're using objective outcome measures that are being administered by people who don't know who's on drug and who's not on drug, we can get some real objective information about is there truly a change in anxiety or aggressive behavior, or impulsivity. So a study helps us make decisions about whether that's the right medication for our child.

Susan Hedstrom:

Medications are highly individualistic from child to child and I think when you start getting into psychiatric medications it gets even more challenging. And not all of our psychiatrists have a strong experience with Prader-Willi. They know, autism, they know anxiety, they know bipolar or depression, but they don't necessarily understand the full nuance of Prader-Willi. So having a publication that is specific to the Prader-Willi population is incredibly helpful. And I can speak to this with personal experience of going to a psychiatrist and saying, I need to try a medication for my son. And he said, well we should try this one because this drug is good, it's well tolerated in the general population. But what I knew from having talked to Prader-Willi experts was that that drug with not the best choice for my son, and I did not want to start there. So I needed to have medical literature to bring to my doctor and he was very receptive once I brought him that information. But if I, as a mom, without an MD or a PhD, just walked into his office and said, well, I want this drug, he would have been much less responsive and willing to listen to me. So having this study published is incredibly important for us so that we can advocate for our children with our doctors.

Participant: This question is for Theresa. You spoke a lot yesterday about some of the research that we're doing, the Foundation's doing, on two genes in specific, which were Magel2 and Snord116. And I'm hoping that you can explain a little bit why the Foundation is looking at those two genes and what implications that would have if the research, and the correction of those two genes would have on the syndrome?

Well, that's what we're trying to figure out. We know both of those genes are really important. Loss of those genes is critical for developing the symptoms that we associate with PWS. So, we know Snord116 because there are about five really rare patients that keep all the other genes but just are missing Snord116 and they have most of the symptoms of PWS. So we know that area is really important. So we're trying to figure out what does the Snord116 do? And we know if Magel2 is mutated, you also get many symptoms that are very similar to a PWS. So that is clearly an important gene as well. What we don't know, and what we will hopefully be able to figure out with the animals that we’re making through the preclinical network, is if we took a background of PWS, like a large deletion like many of our kids have, and we put just Magel2 back on that background, which is a relatively small gene, you could do sort of straight up gene therapy with that, would it improve the situation well enough where that actually might be a good treatment? So we haven't been able to do that before, but we're developing animal models and the cellular models to go ahead and do that kind of thing. So that area is so complex. There's clearly an interplay between all of those genes and we have to understand that a little bit better. But in the meantime, we can look at the specific genes. Does that answer the question?

Participant: My question relates to the last point that John made about research dollars. So we held our first One Small Step event, just before my daughter turned one and I found she's now five. And I find that it gets a little bit more difficult year over a year because you're generally engaging the same people for support in fundraising. So I was just wondering if you had any tips on renewing interest or enthusiasm, and or I guess broadening the reach of fundraising when you're kind of constantly doing it?

You have a very excellent question! I think a lot of people have the same one. We're going to go into this in a little bit more depth after the close of this session and then in our next panel. But I will say that we all get busy and we feel like we can't ask again of our donors sometimes, but if you don't ask, you won't get anything. So, doing something that you're comfortable with, or even pushing your envelope a little bit. Setting up a Facebook fundraiser is a really easy task. It's an easy ask and people give because they want to support you. Your friends want to support you, but they don't know how, so if you give them an opportunity and you say, this would be meaningful. They often will reciprocate; they will show that they want to. They want to do something for you.

Participant: Is there action that's happening from FPWR or other organizations to try and revise the FDA approval so that we can get Growth Hormone approved for what our kids need it for, not just during their adolescents but for their adult lives as well?

Absolutely. So this has been a real focus of mine over the last year, year and a half. And it's a hard problem, and you wouldn't think it would be. There are multiple small trials that have been published that all show benefits for GH in adults. And so it kind of, it seems like a no brainer to us. My son's 25 and we went through the same thing. He got kicked off and it took us about a year and a half to get him back on. So FPWR is doing several things. We are engaged with the large pharmaceutical companies, and working with them and encouraging them to run a trial. The challenge as a advocacy organization, is that we can't go to the FDA and say, you got to approve this. It has to be a sponsor. So it has to be a drug company. So we are working with the large pharmaceutical drug companies to encourage them to do that and do a clinical trial or just put together the information that they need to get an FDA approval. We are working with smaller companies that are looking to break into the market and maybe do a clinical trial in adults. The third thing we are doing is we have funded Laura Degraff who's in Europe and, she has put together 10 clinical sites and we're funding the actual clinical trial in adults. However, to do a large trial with 100 individuals over the course of a year is about a $1M in drug costs. We can't afford that so its taken a long time, but a company has finally agreed to donate the drug and placebo for that trial. So we've got three irons in the fire, and we're working hard on all of them. And, it's taken a lot longer than we'd like, but it's moving, hopefully ahead.

Participant: Is an inherent part of that in order to get that trial to make it a successful trial, having people who are currently on growth hormone agree to go on and potentially not have that drug for a year to see what the effects are of coming off of it?

Well, no, I think what they'll try to do is take people who are not on growth hormone now and put them on, and so there'll be some who don't get drug for six months or a year and then will get drug, and others who get it from the start. But it should not be too hard because the majority of adults are not on growth hormone now, especially in Europe. So there'll be a lot of European sites. They'll also be US sites, but there's several European sites, so they should be able to recruit.

Participant: My question's a little bit broad, but thinking back to several years ago when I first got involved with the Foundation, there were some significant challenges that we were working for, like big meaty challenges. Like there are not enough or no, in some cases, animal models. There was no cell network. We needed collaboration with industry. These are meaty challenges that we've solved over the last several years. What are the meaty challenges for the next five years? I know we talked about what we're hoping and wanting to see, but what are the big things that we need to push through, you know, going forward to make even more progress?

So I'm a geneticist, so I would say understanding how variance in other parts of the genome impact the severity of PWS and now hopefully with new drugs coming on board responsiveness and to those new drugs. So that's what I'd like to sink my teeth into coming ahead.

Maybe I would start first by saying that we've put many things in place but many of them are ongoing and they need to be finalized. We have a strong animal model network. We have good tools. I'm a neuroscientist and I think that is also a very important area to push forward. We’ve seen some really great neurobiologists coming to the field and they are pushing for a better understanding of what circuitry is involved in PWS and fitting in behavior, anxiety, and mental health.

And to add one thing, I don't know if it's super meaty, but it's somewhat meaty, which is also outcome measures and end points. You know, there's a lot of conversation about the hyperphagia questionnaire. It works very well but maybe isn't perfect. And so we are working on developing and considering options and encouraging the development of other ways of assessing important outcomes like hyperphagia, anxiety, even temper outbursts. So continuing to work on developing those outcome measures that can be useful in a clinical trial is a challenge that we are focusing on the next few years. I think will be meaty.

Just one more thing. I think, addressing the cognitive issues in PWS and understanding that there's been so many advances in other intellectual disabilities that I think can be brought to bear on understanding the cognitive disabilities in PWS. That's definitely something that impedes our kids independence. And if there are drug, or non-drug, ways to improve cognition, I think that's definitely something meaty to sink into.

Participant: I didn't go to the conference when my son was born nine years ago, but my husband did and there were 30 people there. So we've definitely been having a moment this weekend of thinking about how much FPWR has grown since we've been in the community. And that's pretty amazing! My question was, speaking on that note, there seems to be a lot of interest in Prader-Willi syndrome from researchers and scientists, which is amazing and it feels like it's growing. So how do you guys as a research team prioritize what projects get funded or what work we actually put the energy and the funds into?

So we spend a lot of time reviewing the landscape and then prioritizing things according to the needs that we hear from all of you. And that we see in our own lives quite frankly. We do have limited funds so we have to consider how we can leverage those funds, what are the ways, the resources that we can develop that many scientists will use? What are the projects that we can fund that will lead to bigger projects that can be funded by pharmaceutical companies or by the NIH? So trying to use these funds wisely, and leverage them as much as we can, is really something that I think we keep in mind all the time.

We also conduct regular meetings with researchers. Just this last Wednesday we held a genetics meeting. It was all inspiring to see the level of expertise in that room. And we shared what do we know? And then we asked what do we need to know and what do we need to do next? So the top experts in the world sat there together and collaborated and put together a list of things that they would prioritize as next steps. We've done that in mental health with a mental health workshop. We've now done this with the genetics meeting and we will continue to have meetings like this annually. So we certainly take in the input from the families as well as the research community to make sure that we're hitting every angle.

And with some risk, I'll use a sports analogy here. We have taken a very methodical peer review approach to reviewing and looking at our research and allowing experts review it. So the hockey analogy goes like this, and the Canadians in the room will appreciate this. In order to win a hockey game, you need 50 to 60 shots on goal. Only three of them have to go in. So one of the things that I want to do going forward is really challenge the research community to say, where can we take some leaps of faith to say, we really need to try this? Because if we are right we could potentially advance some science that we know fundamentally has potential. But if we wait to try and understand the full breadth and full scope of everything, it will take much, much longer. So I'd like this to take some shots on goal, not, not with everything but with some things where we have sort of systematically looked at things and see if we can't get a couple of goals.

donate to FPWR for PWS research

Topics: Research

Susan Hedstrom

Susan Hedstrom is the Executive Director for the Foundation for Prader-Willi Research. Passionate about finding treatments for PWS, Susan joined FPWR in 2009 shortly after her son, Jayden, was diagnosed with Prader-Willi Syndrome. Rather than accepting PWS as it has been defined, Susan has chosen to work with a team of pro-active and tireless individuals to accelerate PWS research in order to change the future of PWS. Inspired by her first FPWR conference and the team of researchers that were working to find answers for the syndrome, she joined the FPWR team in 2010 and led the development of the One SMALL Step walk program. Under Susan’s leadership, over $15 million has been raised for PWS related research.


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Gravel Exudes Mystery Salts

This is one of the more obscure images ever posted on this blog.

IMG_4021gravel480And it’s exact nature is at question. It is a precipitate from crush-and-run gravel that, if located in an outdoor setting in the sun and rain would look like regular gravel.

This was observed in a location under roof of an extensive metal building in which a great deal of farm equipment is housed.

The owner is distraught to find that the entire floor of gravel from a local quarry looks as if it has been strewn with popcorn or crispy cottage cheese or cat puke. It is not a like powdery chalky discoloration of the gravel but is so dense as to totally obscure the rock from view in most places.

I’d guess it’s a calcium salt precipitate and that maybe there is more limestone in this particular gravel source in the county, which I thought was more generally quartz-granite derived.

So help me here, geology and soil chemistry types. Not sure that anything can be done to solve this farmer’s issues with corrosion, but I’d sort of like to better know what’s going on.

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Fred First holds masters degrees in Vertebrate Zoology and physical therapy, and has been a biology teacher and physical therapist by profession. He moved to southwest Virginia in 1975 and to Floyd County in 1997. He maintains a daily photo-blog, broadcasts essays on the Roanoke NPR station, and contributes regular columns for the Floyd Press and Roanoke's Star Sentinel. His two non-fiction books, Slow Road Home and his recent What We Hold in Our Hands, celebrate the riches that we possess in our families and communities, our natural bounty, social capital and Appalachian cultures old and new. He has served on the Jacksonville Center Board of Directors and is newly active in the Sustain Floyd organization. He lives in northeastern Floyd County on the headwaters of the Roanoke River.

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How to Start Adidas Franchise and Authorised Dealership

By | January 11, 2020

India has become a lot more brand conscious when compared to what it was a few years back. In the earlier days, brand was simply associated with cost and people refused to buy branded clothes for this reason. Today, people have learnt to associate brands with quality. They ask for specific brands that have good name in the society in the product line they deal with.

Adidas Franchise Business Opportunity & Dealership

Adidas franchise and authorised dealership in India

Particularly when it comes to footwear and apparels, high awareness and knowledge of fashion makes people go in for brands that have well established themselves in the market. This trend has become more of a status symbol which people yearn for even during normal times.

The style signatures created by such brands have great value in the minds of people adding value to the trend set in peoples mind. Adidas, the international apparel brand is one such signature brand. We will look in detail about the cost of investment and space requirement for becoming a Franchise of Adidas in India.

Becoming an Adidas Franchise is a prudent business decision

Adidas doesn’t need any introduction. The brand is such an established one that it has its own fan following and customers who does not seek buying apparel and footwear of any other brand. Be it the quality or the design, Adidas not only offers all that is the current trend but also creates trend that are followed by other competitive. This way, it acts as the pioneer in setting trends to many in the field dealing with marketing similar products.

Adidas as a strong brand has been monopolizing the sports accessories sector for many years now though some brands tried to establish themselves as competition to Adidas. However, unable to match the quality and price offering that Adidas provided, many brands vanished with time. This has made Adidas an unannounced leader in the sports accessories and apparels industry till date.

Anyone who wants to become a Franchise for the Adidas brand has the brand name as the first and foremost selling point. The brand speaks volumes about itself avoiding the necessity for carrying out any marketing campaign or brand establishing activities. This makes the life of the Franchise easy to focus on just selling and properly servicing the existing customer base.

Cost of Investment and Space requirements to become an Adidas franchise in India

The cost requirement for becoming an Adidas Franchise is approximately 30 Lakhs to 50 Lakhs. This cost is inclusive of whatever marketing cost is needed in the particular area of opening the Franchise. The cost also includes cost of fixtures in the showroom, deposit towards dealership, interior decorations as per Adidas requirements and furniture requirements in the Franchise showroom.

Adidas recommends opening a Franchise in main market areas and shopping malls which has the potential to attract crowds of people. The minimum space requirement recommended by Adidas for opening a Franchise showroom is 1000 Square feet to 1500 square feet.

Probable Return on investment

People who become a Franchise for Adidas can expect the break even in 2 years. Remember this break even period is totally based on many factors like contacts established and sales potentiality of the area in which the Franchise showroom is opened among many other factors.

Adidas India Marketing Ltd,
Plot No-93 Institutional Area, Sector-32, Gurgaon
Landline phone No.: 0124 4569100
Fax No.: 0124-4569160
Email: [email protected]

The return on investment during the first few years can be anywhere between 15% and more based on the efforts and business capabilities of the Franchise owner. Apply for an Adidas Franchise by filling in the form available for the purpose in their official website and become the prestigious Franchise of Adidas, one of the best international brands in India. 🙂

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28 thoughts on “How to Start Adidas Franchise and Authorised Dealership

  1. Adil khan

    I want to open an adidas showroom in kashmir(Anantnag)what should i do please contact me on


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Selenium webdriver assertion jobs

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    Create a test plan: Watch product tutorials videos Aislelabs Flow: WiFi Location Analytics and Real-time Footfall Heatmaps ([login to view URL]) Aislelabs Connect: Social WiFi Marketing Overview ([login to view URL]) Log into our platform at [login to view URL] using the below credentials: User ID: [login to view URL]@[login to view URL] Password: trmibkfypd31 ...

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    Selenium java training 3 days left

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    I assigned this project in mid-December. The goal was to scrab a table of an external website, convey all the data in my site's database, and then obtain an identical table (oddsmatcher) on which each user can filter the data (univocally) to carry out his research. I believe it is 80% / 90% complete. The freelancer who started the job I can no longer track him, perhaps he had problems. you...

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    Selenium webdriver with java support.

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    we have automation trade desktop app we need to to fix some parameters into it because the site has been changed we want to make it work perfectly as the past thank you

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by priyankjini

MyBeesWax is list business website based in West Palm Beach, was created to serve the Palm Beaches as "the" local source for quality service professionals.

image of username priyankjini Flag of India Ahmedabad, India

About Me

I am working on PHP, Coldfusion, HTML, Css, Jquery, Javascript, Ajax, Photoshop etc.. I can assure you of getting quality works. I would like you to give me an opportunity to work with you and AMAZE you with my service.

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[haiku-bugs] Re: [Haiku] #12306: Haiku won't shutdown

  • From: "axeld" <trac@xxxxxxxxxxxx>
  • Date: Thu, 20 Aug 2015 09:32:33 -0000

#12306: Haiku won't shutdown
Reporter: vidrep | Owner: nobody
Type: bug | Status: new
Priority: blocker | Milestone: R1/beta1
Component: System | Version: R1/Development
Resolution: | Keywords:
Blocked By: | Blocking:
Has a Patch: 0 | Platform: All

Comment (by axeld):

The launch_daemon currently has nothing to do with the shutdown process at
all; while it's planned to change this, it's unlikely to be the cause of
any issues there at this time.

Ticket URL: <https://dev.haiku-os.org/ticket/12306#comment:6>
Haiku <https://dev.haiku-os.org>
Haiku - the operating system.

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3 Managers Tips from Someone With Experience

What You Need to Know about Cybersecurity

It is important to appreciate that technology has continued to take shape in different areas, and one of them includes the telecommunication industry. You’ll find that the majority of these technological advancements have made it possible for people to carry out communication between different places within the shortest time possible. We need to appreciate the fact that has provided for easy access especially when it comes to the Internet which in most cases is being used for such purposes due to large volumes of data that can be retrieved in a given search engine. You’ll find that people have continued to improve in terms of how they are using some of these electronic gadgets. For instance, the application of computers very important in most areas because it assists in communication as well as in carrying out purposeful research.

This means that the majority of people have continued to use these electronic devices for communication purposes through various channels such as social networks and email addresses. This implies that there have to be specific security measures which have been put in place to facilitate effective communication for that particular reason. It is enhanced to ensure that two people are communicating enjoy reasonable communication that is not leaked to other unwanted parties through various means. This is therefore described as cyber security in most cases where information is stored and used for reasons that it was meant to be. It also means that that particular information technology company has put in place specific measures that they retrieval and use of a given set of data for various reasons.

You’ll find that the majority of these technology companies have embraced encryption features which in most cases will be protecting consumers information on various platforms. One of the various platforms that have a lot of data includes customer’s database, which in most cases will capture all information relating to the majority of people. This means that there have to be specific features that allow individuals to access the information in a given time for various use. This will require a majority of them to capture in their biometric features which can be used for security purposes, especially when retrieving this information. This is one of the best ways of encrypting information because an individual will only be allowed to get that particular information upon producing their biometric features which will include fingerprints as well as eyes for that particular reason.

Therefore, as a consumer, it is very important for you to consider several factors before getting information Debussy various platforms. One of those factors need to consider are the specific security features which have been installed to facilitate that particular process. You need to find out as to why you are submitting your data and health is greatly protected from unwanted people. It is also important for you to consider that accessibility of these technological equipment is very important, which can assist you in familiarizing with some of them and how they work. One of the very many benefits of cybersecurity is that they will be adequate protection of your information for that particular reason.

The 9 Most Unanswered Questions about Solutions

Managers – Getting Started & Next Steps


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Hockey Games Apps 0

  • Release Date:
  • Current Version:
  • Adult Rating:
  • Developer:
  • Compatibility: iOS, Android
  • Rating:
    686 votes, average: 4.50 out of 5686 votes, average: 4.50 out of 5686 votes, average: 4.50 out of 5686 votes, average: 4.50 out of 5686 votes, average: 4.50 out of 5
    4/5 from 36 votes

caRRage is an addictive arcade racing game, that reveals a post-apocalyptic universe, ruled by mad and desperate drivers. Experience mind blowing races on a number of tough-looking vehicles: starting with a dusty rust-bucket and a van armed with a circular saw and ending with an indestructible truck blasting away everything in its way!

The key feature of caRRage is advanced and thoroughly-designed physics, allowing you to feel at the wheel of a real combat vehicle. Adding unique game modes, like battle in the open arena and the cargo delivery in an armored truck, you get a perfect racing game with lot’s of shooting, collisions and explosions.

Amazing graphics and latest features of the Unity engine, incredibly realistic car crashes and destructions, colorful explosions and shooting. All this will plunge you into the good old arcade racing atmosphere in one of the most dynamic and beautiful games that you’ve ever seen on mobile platforms.

Only caRRage features:

— 23 unique racing locations (racing tracks, open arena, truck route and more)
— Exciting single-player campaign and Wi-Fi-based local multiplayer mode
— Highly detailed game environments in Full 3D: Desert, City, Industrial Area and others!
— 5 game modes: classic race with weapons, delivery mode featuring the Truck, open arena battle, trashball, and ice hockey.
— 9 vehicles (cars, vans, and other deadly “chariots”) with a wide range of upgrades and modifications
— 34 gears, that turn your car into the weapon of vengeance
— 9 types of upgradable weapons
— 40 original decals
— Exclusive soundtracks, created to top the atmosphere of the game

Ram your opponents, use Nitro to overtake them on the turn, blow them up with mines or demonstrate your excellent driving skills and finally: blast your way through with rockets!

Download caRRage and enjoy insane missions in a single-player campaign or challenge your friends in multiplayer.

Official Facebook community:

Official game website:

Download free app for iOS iPhone, iPad or Android APK.

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Bob Quinn made his first draft-day trade as Detroit Lions general manager, and it just so happened to be with his old team, the New England Patriots.

The Lions traded down from the No. 85 pick in the third round, exchanging third-round picks with the Patriots (No. 96 overall) and adding Pick No. 124 in the fourth round.

Quinn did not make any draft-day trades in his first year as Lions GM last year.

He did, however, consummate two other trades with the Patriots organization he spent 16 seasons with. The Lions acquired linebacker Jon Bostic from the Patriots last spring in a deal that did not end up costing them any compensation because Bostic spent the season on injured reserve, and he traded linebacker Kyle Van Noy to the Patriots for an exchange of late-round picks.

With the extra fourth-round selection, the Lions now have six picks in the draft's final four rounds - two in the fourth and sixth, and one in the fifth and seventh.

So far, the Lions have taken linebacker Jarrad Davis from Florida in Round 1, and cornerback Teez Tabor in Round 2.

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500 + Stock Whatsapp Group | Whatsapp Group For Indian Stock Market Advice

Stock Whatsapp Group

Today, you will give some stock Whatsapp Group to people, where you can learn everything related to trading, you all must know that people earn money by trading very much, but the new people have very little knowledge, For those people who have very little knowledge, this group can learn everything by joining this group and related to trading

Here you will get to see many trading groups such as WhatsApp stock market group, Whatsapp group for Indian stock market news, Indian stock market Whatsapp group link, all these you will find groups here, you can learn trading by joining all these groups.

Stock market Whatsapp group link

Also  read the related articles
Doctors Whatsapp Group Links
Mbbs Whatsapp Group Links
Google Whatsapp Group Links

How to Become the Member of Stock Whatsapp Group
  1. Choose any WhatsApp invite group from the above list
  2. Now Hit on the Join Button.
  3. Hurray! Now you are the part of Stock Group

Post a Comment


text:
Department of Post Rajasthan Circle Postman Mail Guard Recruitment 2017

Department of Post Rajasthan Circle Post Recruitment 2017

India Post, Department of Post, Rajasthan Circle, has recently published a notification on its website for the recruitment procedure.

If you are the one who is keenly interested in pursuing your career in this field, you are on correct site. We have compiled all the foremost data about the enrollment procedure that will definitely help you apply for the examination.

The Department of Posts (DoP) is a government-operated postal system in India.

The Department is inviting graduate candidates for the entrance examination. All the interested, enterprising and work enthusiastic aspirants who are the citizen of India can apply for these posts.

Candidates must read the original advertising, the link of which we have provided on this page.

Candidates have to fill up the application form properly as mentioned in the notification else incomplete form may get rejected.
For the further information about the number of posts, exam description, eligibility We recommend you to go through the data that we have provided below. Candidates must precisely read the whole information before applying to the post. Ensure that you should meet all the qualified criteria identified with these occupations.

Vacancy details

Name of Post:

  • Postman
  • Mail guard

The number of vacancies is tentative and subject to change in future.

Pay Scale:

  • 21700/- in level 3 plus admissible allowance

Important Dates of Application:

  • Last date of applying online: 27th November 2017

Educational qualification:

  • Candidates must have passed Class 10th or equivalent from a recognized university.
  • Kindly read the advertisement thoroughly for further info.

Age limit:

Age should not be more than 27 years and not less than 18 years as on 27th November 2017. Age relaxations will be applicable as per the rules.

Selection procedure

Candidates will be selected by strictly on merit basis for a written exam.

Application fee:

Interested general and OBC candidates need to pay the application fee of Rs. 500/-and Candidates belonging to SC/ST/PH are to pay Rs. 100/- to the India Post.

How to apply

The procedure for applying these employments in India is that the candidates need to log on to the official site of the Department of Post in online mode only. There is no other approach to applying for this examination. We advise all the interested candidates to click on the following link for further queries.

Important link:

Disclaimer: the examination data/results/imprints distributed on this site is just for the prompt data to the examinees and does not to be a constitute to be an authoritative record. While endeavors have been made to make the data accessible on this site as credible as it could be. We are not in charge of any accidental mistake that may have published in the information we have distributed on this site. We regret any misfortune to anyone or anything created by any shortcoming, inaccuracy or mistake of the data on this site.

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North Korea struggle in Asian Cup opener

North Korea came into the Asian Cup on poor form having lost out to Hong Kong in the EAFF Cup. They then faced a tough match to begin in Group E against one of Asia’s better sides Saudi Arabia. It was proved to be as tough as expected too with the North Koreans lost 4-0.

North Korea overrun

North Korea set up their team on Tuesday at the Asian Cup to not concede. This, however, did not work for Kim Yong-Jun men as Saudi Arabia run out 4-0 winners. Hattan Babhir and Mohammed Al Fatil scored two first-half goals for the Saudi's. Things got worse for North Korea too before half time when Italian based player Han Kwang-Song was sent off for two first-half bookings.

Previous to this match the North Korean boss knew he had to get his players to play at full potential to stand a chance. This was seen with Kim Yong-Jun saying pre-match “Of course I am expecting us to have a better result than in our tournament history and I have told the players that every player has to be together and play with team spirit for all 90 minutes, everyone has to do their job.”

North Korea did not play to their best however and at no point did they get into the match. This was seen with the side having only 27% possession over the 90 minutes. The issue is they sat back too deep and looked scared to attack. It's got to be said if they want to get out the group they will have to attack in their final two matches. They will though have to do without their best player Han Kwang-Song for one match after his red card.

North Korea still has a chance

Despite the big defeat, North Korea can still qualify from Group E and it should be remembered they did lose to a country who has won the Asian Cup three times. Saudi Arabia last won the Asian Cup when it was last in the UAE before in 1996.

There's still a chance then North Korea can do their best at an Asian Cup since their fourth-place finishes in 1980 in Kuwait. Since then North Korea has exited the Asian Cup at the group stage in every tournament they've qualified for.

To do better North Korea will have to improve massively though when they face Qatar on Sunday. They will need to do without their starman but not all hope is lost just yet.

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The ONE Group Expanding STK Into Mexico

The ONE Group Hospitality, Inc. announced that the company has signed a licensing agreement with Grupo Restaurantero Dinar, which will allow GRD to open four locations in Mexico.

“Our expansion into Mexico is an exciting step as we continue to grow our brand internationally. We are delighted to be partnering with Grupo Restaurantero Dinar as we enter this new market,” says Manny Hilario, CEO, The ONE Group. “Similar to our previous licensing deals, these locations will require no capital contribution while driving high-margin revenue, the driving force behind our growth plans.”

“We are very excited about our licensing partnership with The ONE Group. The first STK in Mexico is expected to open in Mexico City, at Presidente Masaryk Avenue (Tennyson 117), in the heart of the city’s dining and entertainment district on Polanco alongside some of the best commercial and retail tenants in Mexico City. A second STK is planned in Guadalajara at Andares Lifestyle Center located in the city’s Zapopan District. Both are expected to open in late 2018. The third and fourth restaurants are anticipated to open in Monterrey and Cabo,” says Guillermo Arciniega, from Grupo Restaurantero Dinar.

STK Mexico City is expected to have indoor and terrace seating for 175 guests, whilst STK Guadalajara will seat 150 between the restaurant and the terrace. Both restaurants will feature STK's classic menu and signature dishes along with the brand’s signature décor.

News and information presented in this release has not been corroborated by FSR, Food News Media, or Journalistic, Inc.


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Latest news from FTA

Fta News

International Women's Day 2019

Charlotte Berrystone08 Mar 2019

Today we are celebrating the significance of International Women's Day.

Established in 1911, this day is a focal point for the movement of women's rights. Just as we will celebrate the achievement of men on 19th November, today we are taking time to celebrate the social, economic, cultural and political achievements of women and most notably, pilots.

the first women in aviation

Amelia Earhart is probably the most well known women in aviation history, however there have been many other pioneers. The first woman to pilot a heavier than air craft was a french sculptor and aviator, called Therese Peltier (in 1908), and just two years later, Baroness Raymonde de Laroche was the first woman to be granted her pilot's licence. However it was 62 years before Yvonne Pope (who started out as a flight attendant) became the first woman to fly a commercial jet.

Last year marked the centennial anniversary of the First World War and a significant moment in the history of transport. You can view a timeline of 100 years of women in transport and its impact here:

However our focus today is on the present, and our female pilots who have overcome their own challenges, and inspire us and other aviation enthusiasts.

Read More

Posted in: be a pilot, women in aviation, female pilots, why be a pilot

Success at Virgin Future Flyers

Charlotte Berrystone21 Feb 2019

We attended Virgin Atlantic's Future Flyer and Expert Engineers Day.

The event was organised with the intention to inspire children aged 9-16 years who may not have considered a role within aviation - a dynamic and expanding industry.

We were thrilled to be invited to the event and able to offer our support to such a local, and influential brand.

Read More

Posted in: women in aviation, flying, female pilots, cadet, why be a pilot, virgin

Ana offers an insight into life as a pilot with airBaltic

Alexandra O'Loughlin28 Aug 2018

Why did you train to become a pilot?

When I was 19 and a student I started to work as a secretary in an aviation company.  Within months of working there, I grew a passion for aviation and fell in love with the idea of being a pilot. I started in flight operations and became exposed to pilots, hearing their stories and how they explained things.

Despite my growing interest, I knew the cost and felt like it was impossible for me, something that was entirely out of my reach.

No turning back

I saved every penny I could and eventually saved up enough money to complete my Private Pilot’s Licence (PPL). For me, it made sense to start by only focusing on that aspect of the training. I told myself that the PPL was financially a lower risk than enrolling straight onto an integrated course. It gave me time to save just enough money and was an excellent place to start my training. I felt that if I succeed at this stage, it will give me the knowledge and confidence to decide whether I could progress on to the more advanced training required of airline pilots.

The problem was there would never be any turning back after experiencing what it was like to fly – I instantly became addicted. I knew that I would never be happy if I didn’t now follow my dream.

Finding the right flight school

I researched all the pilot training, and my boss who is also a mentor to me said to go to the states and train over there. It was a UK certified flight school but based in Florida, and you gained an EU licence at the end of your training. It was only possible with thanks to funds from my parents and a personal loan. After I had completed my commercial training, I had to find somewhere to complete my IR (in the US you cannot do your instrument rating).

I looked around Europe and the UK and first looked at a few, large flight schools based in the South of England and their prices were well out of reach. I was also very disappointed by their customer service. Through further research, I discovered FTA and everything felt happy. I got a response within hours and had all the answers to my questions. Stuart (the Admissions Officer at the time) was friendly and helpful.

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Posted in: Pilot jobs, women in aviation, flight instructor, female pilots, careers

Ana, a modular student from FTA, explains how valuable working as a Flight Instructor was for her both personally and professionally

Charlotte Berrystone02 Aug 2018

Ana, a qualified Flight Instructor turned pilot explains what life as First Officer for airBaltic is like, and how she and her partner make it possible to both work as pilots and still enjoy a happy family life.

Why did you want to be a pilot?

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Posted in: Pilot jobs, women in aviation, instructor, pilot trainnig, flight instructor, female pilots, why be a pilot, careers

International Women's Day - why are only 3% of pilots female?

Alexandra O'Loughlin08 Mar 2018

Estimates from the International Society of Women Airline Pilots (ISA) in 2015 suggested that there were about 4,000 women pilots worldwide that's just 3%. Another estimate, by easyJet, puts the balance at 5%, with 6% of its own flying staff female.

Read More

Posted in: cost of pilot training, female pilots, aviatrix, cadet, why be a pilot

Female students discovering the endless possibilities in aviation

Alexandra O'Loughlin23 Nov 2017

Over 37% of FTA’s October intake (on the Integrated Flight Deck Programmes or FDP) were female. If this were any other academic course that statistics would not be so unusual. But with over 94% of pilot jobs held by men, this number suddenly sounds very exciting!

Read More

Posted in: become a pilot, female pilots, aviatrix, cadet

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Mp3: Damon & Naomi in London in 2001 - Attention Shoppers

in categories:

I don't have many recordings of Damon & Naomi - at most gigs since this one in 2001 my taping buddy hasn't been able to tape for various reasons (and had one failure - and doesn't come out so often these days). This was a great show, support had come from The Clientele (first or second time I'd seen them) and The Trembling Blue Stars (sadly neither of their sets were taped). Damon & Naomi were over with Michio Kurihara on the tour that would end with the "Live in San Sebasitan" deception (go read your Sub Pop Years liner notes).

I didn't often bother making sleeves for the recordings I have, but I did for this one. The picture was not from London but from Holland (I think) on the same tour, and was from a set sent to me to put on the website by the photographer Stefan Claudius. I didn't get permission to bung it on my CD sleeve but then it was never meant for sharing. Stefan's photos also turned up in the "Song to the Siren" CD booklet.

Anyway... great show - you can see my original review here.

Download Attention Shoppers from Mediafire (93MB) (booklet / insert)

On Fire | 30

A 30th anniversary celebration of Galaxie 500's masterpiece

On Fire 30 CD sleeve (design: John Conley)
Buy On Fire | 30


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Stromberg Reversible Peach Finish Belt BT005

Out of Stock

Stromberg Reversible Peach Finish Belt. A reversible golf belt made from the finest quality leather with alternating red and white sides. Finished with a classic buckle with subtle Stromberg branding. 100% Leather - One Size

Free 2-3 Day Delivery by Royal Mail on all UK orders.

Free Express Delivery by DPD on UK orders over £125 (Std cost £1.95).

Our full shipping information including International options can be viewed here

** Extended Christmas Returns **

Orders placed between 1st November and Christmas Day can be returned for exchange or credit note up until the 14th Jan 2020. This does not effect your statutory rights.

Our standard returns policy allows 14 days from the receipt of your order to return it for refund. We will refund the value of the returned items using the original payment method and within 2 working days of receiving the goods. Our full returns policy can be viewed here


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Outdoor Digital 6 Sheet

Future Systems Outdoor Digital 6 Sheet outdoor digital display provides the perfect solution to outdoor advertisement and information problems. We proudly present the latest in display technology, the Fuzion D6.

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G-RES - GEO SYSTEMS GMBH (limited liability company for renewable energy systems) is specialized in the design, production and distribution of products for the extraction of renewable energy to water/ground heat pumps.

In addition to the invention allocated for the probe with immersion heater in the ground other inventions are required as well, which relate to the heat collection from waste water/water.

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Thorndike Press

The Amish Christmas Letters

  • Patricia Davids
  • Sarah Price
  • Jennifer Beckstrand
  • Offered By:
  • ISBN-10: 1432854569
  • ISBN-13: 9781432854560
  • DDC: SC
  • Shipping Weight: 1.25 lbs ( .57 kgs)
  • 498 Pages | Paperback
  • Published/Released November 2018

This product is part of:

Relationship Reads - Large Print Standing Order Plan

Features a mix of contemporary women’s fiction, coming-of-age, romance, and other genres highlighting human connections.

With Christmas around the corner, it’s time for Amish families to include holiday greetings in their circle letters, each writer adding to a growing collection as it travels on to the next. In this delightful trio of stories, three cousins scattered across the country share their blessings - and news of romantic surprises.


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Impressions: Shenmue III’s Battle Rally DLC is a fun distraction, but little else

Much like the larger main game it’s attached to, Shenmue III’s first post-launch DLC release, Battle Rally, feels less like a cohesive experience and more like a half-baked mish-mash of gameplay ideas and concepts. It’s technically functional and can potentially add a few hours onto a typical Shenmue III playthrough, but what it doesn’t do is the one thing I’m guessing fans wanted it to: advance the game’s story.

Rather than revisit the narrative threads left hanging after the conclusion of Shenmue III’s main story, Battle Rally instead offers up a pair of mini-games that are entirely divided from protagonist Ryo Hazuki’s quest for revenge. Die-hard fans might enjoy getting to spend a little more time in the Bailu Village region where both mini-games are set, but those who care more about the Shenmue story and world will find it tougher to justify investing in the $8 DLC.

Speed Up, Slow Down

Battle Rally is directly accessible from Shenmue III’s main menu, but even if a player has purchased the DLC they must first reach the Niaowu region in the game’s story mode before they can try out the new mini-game modes for themselves. Once a player unlocks access to Battle Rally, they’ll discover that the actual ‘Battle Rally’ mode is just one of two modes included in the DLC, the other being a scavenger hunt mode aptly called ‘Bailu Chan Hunt.’

In the Battle Rally portion of the DLC, players must sprint along a linear path in the hopes of reaching the final goal. Along the way they pass through checkpoints to increase the track’s timer and fight enemies to improve their final score. Said final score is tracked on a leaderboard of sorts, but that “leaderboard” is mostly made up of fictitious competitors whose names and birthdates match those of NPC’s from the main game (this is about as close as the Battle Rally DLC ever comes to linking its mini-games to the larger Shenmue III story).

Perhaps the most intruiging element of the Battle Rally mini-game is that, for the first time ever in the entire Shenmue series, players can control other characters besides Ryo Hazuki. Along with Ryo, the Battle Rally roster includes Ryo’s grumpy friend Wuying Ren and a new female character named Wei Zhen who appeared as a sparring partner NPC in the main game.

Each of the three playable characters has their own attack combos and special moves, and they also each have their own custom values for the mode’s two combat stats: health and attack power. Ryo has more health but less attack power, Ren has higher attack power and lower health, and Wei Zhen is equally balanced in both stats.

As for Bailu Chan Hunt, it’s similar to the optional Niaowu Chan Hunt players could participate in during the main game. As they walk around different parts of Bailu Village, players must track down and find small Bailu Chan figurines hidden in the environment. A helpful “Bailu Chan Tracker” mechanic helps players zero in on the well-camouflaged collectibles, and the Bailu Chan Hunt experience itself is worth at least checking out since finding collectibles is how players unlock stat upgrades and additional courses for Battle Rally.

Sadly, unlike in Battle Rally, only Ryo is playable in Bailu Chan Hunt. However, the mode does at least allow players to sniff around for Bailu Chan figures for as long as they want without any sort of time limit. The rewards that players can unlock through Bailu Chan Hunt also offer some semblance of progression, but such progression never moves beyond the bounds of the Battle Rally DLC itself.

Limited Scope

Shenmue III’s disappointingly obtuse and unintuitive combat mechanics quickly sap away what little appeal the Battle Rally mini-game had to begin with. Each of the three playable characters has five special moves (some of which are actually multi-hit combos) attached to a specific series of button inputs, and special moves can also be instantly executed by selecting them and pressing the dedicated special move button (R2 on PS4 for example).

Given the tight time limits imposed on each Battle Rally course, the most efficient strategy for dealing with the thugs that block your progress is to just equip a speedy special move or combo and just spam it the moment you’re in striking distance. Of course, while this is a pretty easy strategy for Ren and Wei Zhen to implement, such is not the case for Ryo and his woefully pitiful array of assigned special moves (for some reason Ys Net gave Ryo both the Elbow Assault and Counter Elbow Assault even though their Shenmue III iterations are virtually the same).

Aside from the stat upgrades unlocked through Bailu Chain Hunt, you also can’t customize the three playable Battle Rally characters in any way. Their special moves are permanently locked to the same small selection of five (even though Ryo can learn many, many more in the main game), and there’s nothing in the way of unlockable outfits or other customization items. This means that, aside from chasing top times on a mostly meaningless leaderboard, the Battle Rally mini-game has virtually no replay value.

Shallow Outing

After playing through Shenmue III proper, my expectations for what the game’s DLC would entail were admittedly not very high. Still, it’s disheartening to see that, whether because of limited resources or a limited inclination, the best Ys Net could produce for the very first Shenmue DLC ever was a cobbled-together and underbaked side distraction which relies almost entirely on recycled game assets.

There’s still at least one more piece of DLC on the way for Shenmue III, so maybe Ys Net is just saving its best for last. Here’s hoping the next DLC offers an experience that’s a little more substantial and, more importantly, expands the world of Shenmue in a more meaningful way.


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We offer you

  • Career in a world leading game developer
  • Promotion based on excellence
  • Performance based reward
  • Recognition and reward program
  • Birthday celebration
  • Annual staff trip
  • Annual health check
  • Various in-door events
  • Games and sport clubs
  • Tons of team building activities
  • Modern working facilities
  • Game room: PS3, Xbox, Wii
  • And so much more…

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Technical 3D Artist, Ho Chi Minh

Reference: Ho Chi Minh, Art

Department: Art

Location: Ho Chi Minh

Company Description

Are You Looking for a Great Place to Work?

Join the Game!

About Gameloft

Leader in the development and publishing of games, Gameloft® has established itself as one of the top innovators in its field since 2000. Gameloft creates games for all digital platforms, two of which are featured in the “Top 10 iOS Games by All-Time Worldwide Downloads” from App Annie. Gameloft operates its own established franchises such as Asphalt®, Order & Chaos, Modern Combat and Dungeon Hunter and also partners with major rights holders including Disney®, LEGO®, Universal, Illumination Entertainment, Marvel®, Hasbro®, Fox Digital Entertainment, Mattel® and Ferrari®. Gameloft distributes its games in over 100 countries and employs 4,600 people worldwide. Every month, 98 million unique users can be reached by advertisers in Gameloft games with Gameloft Advertising Solutions, a leading B2B offering dedicated to brands and agencies. Gameloft is a Vivendi company.

All trademarks referenced above are owned by their respective trademark owners.

Gameloft Studio in Ho Chi Minh City is hiring top talents to enforce its creative agency, the unique award-winning team of Gameloft working on premium and gamified digital advertising solutions for most famous brands around the globe. Excited to be part of that team in the heart of the coolest city of Vietnam?

Then join us!

Job Description

Do you have the feeling that your tasks never change and you need to find new challenges, new
environment and something to stir your creativity? Get over here and see what await you on the other
side, at Gameloft Vietnam:

  • Indulging yourself in different 3D projects, you will not be modeling and sculpturing, unless you want to, instead, you your focus is to make the player’s eyes pop with all those wonderful VFX, environment lighting and post-processing;
  • Giving your own voice in brainstorming sessions for game ideas and artistic styles, optimize work flow or even introduce new code and script to the team, everyone like new things;
  • Providing technical support and problem solving when working in the team, your experience and coding knowledge will allow you to play a more active role in your team;
  • Seeing yourself as a bridge, a communicator between your team and programmers, their languages may not align but you need to know how to connect them to develop new tools or techniques which create best possible art quality;
  • And also, keep a habit of reporting your tasks status or giving any suggestion to your supervisors or producers, it is good to let them know your thoughts, ideas or proposal to make your team better.

There are many things for you, but you should be at least ready for it:

  • Academic background in art or equivalent, unlike someone, we do count 3 and higher, that should be in years of experience as Technical Artist, it would be great for you to show us those skills you have been sculpting ‘til now in your portfolio;
  • Excellence in 3D and 2D software with knowledge on some hardcore stuff like particle FX, lighting, special effects and put them into game engine for real-time render;
  • Some coding knowledge on C#, High Level Shading Language (HLSL), MAXScript or Node-based Shader in Unity Editor won’t be a bad idea;
  • English skill is a no brainer, we have a mix bag of talents from around the world, here, it is the best way to communicate and connect with people around the studio and beyond;
  • Having good sense of initiatives, be original and inventive;
  • Open-minded with  flexibility in thinking, but never lose sight of your responsibility;

Additional Information

Where will you be heading to?

  • A world of more vivid colors, bolder landscapes, finest coastlines and most compelling history, you cannot find any place quite as enriching, enlivening and exotic on earth as Vietnam. We have cities where lives are both chaotic and captivating, yet never lose its traditional beauty: gracious and graceful destination offering endless generosity and the best food you could ever taste.
  • In the heart of the southern part of Vietnam stands a bustling, dynamic and industrious city, Ho Chi Minh, the economic capital and the cultural trendsetter. Being embraced by both traditional and modern beauty, Ho Chi Minh is an ideal destination of interest regardless of your interest.
  • Don’t want to get lost first step in the city, we’ve got you covered:

Why join Gameloft?

  • You want to be part of an exceptional experience, within a company that is constantly growing.
  • You want to work with talented people who are industry pioneers.
  • You want to join a global company and meet great people around the world from all walks of life.
  • Or, you are just looking for a fun place to work!

What Gameloft Vietnam can offer you?

  • Fun work experience with world prestigious game products
  • Teamwork with game professionals
  • Training and dynamic career growth
  • Performance based reward and recognition
  • Creative and friendly working environment
  • Healthcare, sponsored clubs, enjoyable staff activities

We can’t wait to find our next great talent!

  • Please note that only selected candidates will be contacted and your CV will be saved in our files for a period of 6 months.
  • Want to know more? Please visit our Website:

© Gameloft 2019. All rights reserved. Gameloft and the Gameloft logo are trademarks of Gameloft in the U.S. and/or other countries.
All other trademarks are the properties of their respective owners


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Remnant: From The Ashes – How To Get The Assault Rifle

The Assault Rifle is an excellent weapon in Remnant: From The Ashes. The weapon’s accuracy and rate of fire make it an ideal option to deal with multiple enemies at medium range. You can also use it at long ranges using the weapon’s tap fire, allowing you to pick off enemies from a distance.

Remnant: From The Ashes – How To Get The Assault Rifle

Assault Rifle Dungeon Map

To find the Assault Rifle, you need to have saved the Root Mother from the church, which is part of the storyline. If you haven’t reached this yet, continue playing until you do. After you do, head to the golden portal through the broken wall of the church.

Once you move through the portal, use the checkpoint to get back all your health and ammo. The dungeon you want should be in this area, but the entry point varies. Remnant works off-world seeds, so it may not be the same location as in my game. The dungeon you want has a ramp down to a broken wall at the start, and the area has water everywhere, and strange plants.

Monkey Key Location Supply Run

When you get inside, there are exploding enemies and fat ones with daggers. From time to time, more dangerous threats do spawn but make your way slowly through the dungeon. There’s a branching path, but both roads lead to the same place.

On the map above, you can see the layout of the dungeon. The white player marker is at the start, while the other checkpoint on the right side indicates the end. The red rectangle marks the location of an item you need to get if you want the Assault Rifle. You’re going to find the Monkey Key at this location. When you acquire the key, go down to the room behind the checkpoint on the right side of your map. You need to use the Monkey Key to open the door. Go inside and pick up everything in the room, including the Assault Rifle.

When you have the Assault Rifle, you can use the checkpoint to move to another area, or head back to Ward 13. Be sure to grab plenty of Iron to upgrade the Assault Rifle to +5, although it should drop at +3, so it won’t take much to get there.