Alright, let's solve this problem step by step. We have 622353 and 94242, and we're subtracting the second number from the first.

Step 1: We'll start by subtracting the digit 2 and the borrow 0 from 3 in column 1 and get 1.
1 is the first digit of our result.

Step 2: We'll start by subtracting the digit 4 and the borrow 0 from 5 in column 2 and get 1.
1 is the next digit of our result.

Step 3: We'll start by subtracting the digit 2 and the borrow 0 from 3 in column 3 and get 1.
1 is the next digit of our result.

Step 4: We'll start by subtracting the digit 4 and the borrow 0 from 2 in column 4 and get -2.
We add -2 to 10 and get 8 as the next digit of the result.

Step 5: We'll start by subtracting the digit 9 and the borrow 1 from 2 in column 5 and get -8.
We add -8 to 10 and get 2 as the next digit of the result.

Step 6: We'll start by subtracting the digit 0 and the borrow 1 from 6 in column 6 and get 5.
5 is the next digit of our result.

So, 622353 - 94242 = 528111.