In broad terms, transformation design is a human-centered, interdisciplinary process that seeks to create desirable and sustainable changes in behavior and form – of individuals, systems and organizations. It is a multi-stage, iterative process of applying design principles to large and complex systems.

Its practitioners examine problems holistically rather than reductively to understand relationships as well as components to better frame the challenge. They then prototype small-scale systems – composed of objects, services, interactions and experiences – that support people and organizations in achievement of a desired change. Successful prototypes are then scaled.

Because transformation design is about applying design skills in non-traditional territories, it often results in non-traditional design outputs.3 Projects have resulted in the creation of new roles, new organizations, new systems and new policies. These designers are just as likely to shape a job description, as they are a new product.3

This emerging field draws from a variety of design disciplines - service design, user-centered design, participatory design, concept design, information design, industrial design, graphic design, systems design, interactive design, experience design - as well as non-design disciplines including cognitive psychology and perceptual psychology, linguistics, cognitive science, architecture, haptics, information architecture, ethnography, storytelling and heuristics.

History
Though academics have written about the economic value of and need for transformations over the years7,8, its practice first emerged in 2004 when The Design Council, the UK's national strategic body for design, formed RED: a self-proclaimed "do-tank" challenged to bring design thinking to the transformation of public services.1

This move was in response to Prime Minister Tony Blair's desire to have public services "redesigned around the needs of the user, the patients, the passenger, the victim of crime".3

The RED team, led by Hilary Cottam, studied these big, complex problems to determine how design thinking and design techniques could help government rethink the systems and structures within public services and possibly redesign them from beginning to end.3

Between 2004 and 2006, the RED team, in collaboration with many other people and groups, developed techniques, processes and outputs that were able to "transform" social issues such as preventing illness, managing chronic illnesses, senior citizen care, rural transportation, energy conservation, re-offending prisoners and public education.

In 2015 Braunschweig University of Art / Germany has launched a new MA in Transformation Design. In 2016 The Glasgow School of Art launched another masters program "M.Des in Design Innovation and Transformation Design". In 2019 the University of Applied Sciences Augsburg / Germany launched a masters program in Transformation Design.

Process
Transformation design, like user-centered design, starts from the perspective of the end user. Designers spend a great deal of time not only learning how users currently experience the system and how they want to experience the system, but also co-creating with them the designed solutions.

Because transformation design tackles complex issues involving many stakeholders and components, more expertise beyond the user and the designer is always required. People such as, but not limited to, policy makers, sector analysts, psychologists, economists, private businesses, government departments and agencies, front-line workers and academics are invited to participate in the entire design process - from problem definition to solution development.6

With so many points-of-view brought into the process, transformation designers are not always 'designers.' Instead, they often play the role of moderator. Though varying methods of participation and co-creation, these moderating designers create hands-on, collaborative workshops (a.k.a. charrette) that make the design process accessible to the non-designers.

Ideas from workshops are rapidly prototyped and beta-tested in the real world with a group of real end users. Their experience with and opinions of the prototypes are recorded and fed back into the workshops and development of the next prototype.

See also
 Human-centered design

Sources
  RED's homepage
 https://www.designcouncil.org.uk/ Design Council's homepage
  White Paper published by RED which discusses transformation design
  RED's website page which talks about transformation design
 http://www.torinoworlddesigncapital.it/portale/en/content.php?sezioneID=10 Interview with Hilary Cottam at World Design Capital
 https://web.archive.org/web/20070818190054/http://www.hilarycottam.com/html/RED_Paper%2001%20Health_Co-creating_services.pdf Whitepaper on co-creation
 The Experience Economy, B.J. Pine and J. Gilmore, Harvard Business School Press 1999. Book discussing the economic value and importance of companies offering transformations
 The Support Economy, S. Zuboff and J. Maxmin, Viking Press 2002. Book discussing the need for companies and governments to realign themselves with how people live
 Transformationsdesign - Wege in eine zukunftsfähige Moderne, H. Welzer and B. Sommer, oekom 2014
 Transformation Design - Perspectives on a new Design Attitude, W. Jonas, S. Zerwas and K. von Anshelm, Birkhäuser 2015

Design
Humanism


Protein kinase LYK5, also known as LYK5 or STRADα, is a human protein and also denotes the gene encoding it.

Function
Endogenous LKB1 and STRADα form a complex in which STRADα activates LKB1, resulting in phosphorylation of both partners. Removal of endogenous LYK5 by small interfering RNA abrogates LKB1-induced G1 phase arrest. STRADα stabilizes LKB1 protein both in vivo and in vitro, and is capable of eliciting multiple axons in mouse embryonic cortical cultured neurons when overexpressed with LKB1. STRADα is highly spliced in vivo, and this is both developmentally regulated and tissue-specific, but the unique functions of the splice variants are not yet understood.

Disease linkage
Mutations in the LYK5/STRADα gene are associated with polyhydramnios, megalencephaly and symptomatic epilepsy (collectively known as the PMSE syndrome).

Interactions
STRADα has been shown to interact with LKB1 and MO25.

References

Further reading


The following article presents a summary of the 1910 football (soccer) season in Brazil, which was the 9th season of competitive football in the country.

Campeonato Paulista

Final Standings

sc corinthians p declared as the Campeonato Paulista champions.

State championship champions

References

 Brazilian competitions at RSSSF

Seasons in Brazilian football
Brazil


Events from the year 1759 in Ireland.

Incumbent
Monarch: George II

Events
Restrictions on import of Irish cattle into England are removed.
Henry Flood enters the Parliament of Ireland as a member for Kilkenny.
Planned French Invasion of Britain: France considers offering the Kingdom of Ireland to a Stuart pretender.
Formation of the Irish Catholic Committee, of Dublin merchants and professionals loyal to the British monarchy.
31 December – Arthur Guinness leases the St. James's Gate Brewery in Dublin.

Arts and literature
West front of Trinity College Dublin on College Green completed by architects Henry Keene and John Sanderson.

Births
5 March – Thomas Bray, Roman Catholic Archbishop of Cashel (died 1820).
9 September – Hercules Taylour, soldier and politician (died 1790).
Adam Buck, miniaturist and portrait painter (died 1833 in London).
James Craig, politician (died 1833).
Charles Osborne, lawyer and politician (died 1817).
Approximate date
Sir James Galbraith, 1st Baronet, politician (died 1827).
Robert Philson, soldier and politician in the United States (died 1831).

Deaths
16 February – Bartholomew Mosse, surgeon, impresario, founded the Rotunda Hospital in Dublin (born 1712).
Richard Pockrich, inventor of the Angelic organ (born c. 1690).
Henry Singleton, judge (born 1682).

References

Years of the 18th century in Ireland
Ireland
1750s in Ireland


Michele Piccolo (born 1 September 1985) is an Italian footballer who plays as a forward for San Colombano (as of the 2017–18 season).

Career

A.C. Milan
Born in Badia Polesine, Veneto, Piccolo started his career at Veneto club Padova, about 50 km to his born place. In September 2002, he joined Milan youth teams. He played his first and only match for A.C. Milan first team on 24 May 2003, the last Serie A match of the season and the match before 2003 UEFA Champions League Final and 2003 Coppa Italia Final. In the match, he partnered with Alessandro Matri and neither one scored. The match ended with 2-4 lost to Piacenza as Milan almost rested all the regular starter.

In the next season, he played all the time at Primavera (U20) Team and not played in the first team. In 2004-05 season, he left on loan to Prato of Serie C1 along with Matri but in mid-season joined Pizzighettone at Serie C2.

Pizzighettone
Piccolo joined Pizzighettone in January 2005 and followed the team promoted to Serie C1 in 2005. He played 28 league matches and scored 6 goals in 2005–06 Serie C1 season and the club decided to sign him in co-ownership deal in 2006, for a peppercorn fee of €1,000. In 2006-07 season, Piccolo only played 8 league matches. After the club relegated back to Serie C2 at the end of season, the club sign him permanently from Milan. Piccolo then played 42 league matches in two seasons and followed the club relegated to Serie D (non-professional) in 2009.

Fiorenzuola
Piccolo joined Fiorenzuola of Serie D in 2011-2012 and 2014-2015 season.

Pro Piacenza
Piccolo joined BP Pro Piacenza of Serie D in 2012-2013 and 2014-2015 season.

Vigor Carpaneto
Piccolo joined Vigor Carpaneto of Eccellenza in 2015-2016 season, where it remained until January.

Crema 1908
Piccolo joined Crema 1908 of Eccellenza in 2015-2016 season from January to the end of the championship.

Nibbiano & Valtidone
Piccolo joined Nibbiano & Valtidone of Eccellenza in Emilia-Romagna in 2016-2017 season.

San Colombano
Piccolo joined San Colombano of Eccellenza in Lombardia in 2017-2018 season.

References

External links
 Profile at FIGC

 LaSerieD.com

Italian men's footballers
Italy men's youth international footballers
AC Milan players
AC Prato players
AS Pizzighettone players
AS Pro Piacenza 1919 players
Serie A players
Men's association football forwards
Sportspeople from the Province of Rovigo
1985 births
Living people
Footballers from Veneto


Crumbs protein homolog 3 is a protein that in humans is encoded by the CRB3 gene.

Function

This gene encodes a member of the Crumbs family of proteins. This protein may play a role in epithelial cell polarity and is associated with tight junctions at the apical surface of epithelial cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

References

External links

Further reading


Jeffrey Dee McCurry (born January 21, 1970) is an American former professional baseball pitcher. He appeared in parts of five seasons at the Major League Baseball (MLB) for the Pittsburgh Pirates, Detroit Tigers, Colorado Rockies, and Houston Astros.

Playing career
McCurry was drafted by the Pirates in the 14th round of the 1990 MLB draft. He did not sign a contract with Pittsburgh until May 25, 1991. He made his professional debut with their Rookie league Gulf Coast Pirates and Class A (Short Season) Welland Pirates in 1991. McCurry recorded a 2.57 ERA in 6 games with the GCL Pirates and an 0.57 ERA in 9 appearances with Welland.

McCurry split the 1992 season between the Class A Augusta Pirates and the Class A-Advanced Salem Buccaneers. He recorded a 3.30 ERA in 19 outings with Augusta. In 30 games with Salem, he recorded a 6–2 record and an earned run average of 2.87 over 62.2 innings. In 1993, McCurry made 41 appearances for Salem and tallied a 1–4 record and a 3.89 ERA. He also appeared in 23 games for the Class AA Carolina Mudcats, recording a 2.79 ERA in 29 innings. He spent the entire 1994 season with Carolina. Appearing in 48 games, McCurry totaled a 6–5 record and a 3.21 ERA in 81.1 innings.

Post–playing career
McCurry now coaches baseball at St. Thomas High School in Houston, Texas.

See also
 List of Major League Baseball players from Japan

References

External links

1970 births
Living people
American baseball coaches
American expatriate baseball players in Canada
American expatriates in Japan
Augusta Pirates players
Calgary Cannons players
Carolina Mudcats players
Colorado Rockies players
Colorado Springs Sky Sox players
Detroit Tigers players
High school baseball coaches in the United States
Houston Astros players
Major League Baseball pitchers
Major League Baseball players from Japan
Nashville Sounds players
New Orleans Zephyrs players
Pittsburgh Pirates players
Salem Buccaneers players
San Jacinto Central Ravens baseball players
Baseball people from Tokyo
TCU Horned Frogs baseball players
Toledo Mud Hens players
Welland Pirates players
Baseball players from Houston


Delta and Notch-like epidermal growth factor-related receptor is a protein that in humans is encoded by the DNER gene.

References

Further reading


U3 small nucleolar ribonucleoprotein protein IMP4 is a protein that in humans is encoded by the IMP4 gene.

References

Further reading


Ancelle (; ) is a commune in the Hautes-Alpes department in southeastern France. The village is a tourist destination for both the summer and winter seasons, offering a range of sporting activities such as hiking, cross country skiing and camping. Ancelle has a small, neighbouring village called Les Taillas, located to the south of the main town centre.

Population

See also
Communes of the Hautes-Alpes department

References

External links
Website at ancelle.fr

Communes of Hautes-Alpes
Dauphiné


Avançon () is a commune in the Hautes-Alpes department in southeastern France.

Population

See also
Communes of the Hautes-Alpes department

References

Communes of Hautes-Alpes
Dauphiné


Yuli Teodorovich Dunsky (, 22 July 1922 in Moscow, Russia – 23 March 1982 in Moscow, Soviet Union) was a Soviet screenwriter.

Most works made together with Valeri Frid. Both of them were imprisoned in Gulag labor camps.

Filmography

Writer
 1984 And Then Came Bumbo
 1983 Every Tenth
 1983 Adventures of the Little Muk
 1982 The Story of the Voyages
 1981 Don't be Afraid, I'm with You
 1980 Air Crew
 1980 The Gadfly
 1979 The Adventures of Sherlock Holmes and Dr. Watson: Bloody Signature
 1979 The Adventures of Sherlock Holmes and Doctor Watson: Acquaintance
 1976 How Czar Peter the Great Married Off His Moor
 1976 Widows
 1974 High Title / For the Life on Earth
 1973 High Title / I, Shapovalov T. P.
 1971 The Shadow
 1970 Red Square
 1970 Shine, Shine, My Star
 1969 An Old, Old Tale
 1968 Bare et liv - historien om Fridtjof Nansen
 1968 Two Comrades Were Serving
 1965 Once Upon a Time There Was an Old Man and an Old Woman
 1964 An Unthinkable Story
 1962 Seven Nannies
 1962 Sixteenth Spring
 1960 The Same Age
 1957 The Case at Mine Eight

References

External links

1922 births
1982 deaths
Soviet screenwriters
Male screenwriters
20th-century screenwriters
1982 suicides
Gerasimov Institute of Cinematography alumni
Gulag detainees
Suicides by firearm in the Soviet Union
Burials at Donskoye Cemetery
Soviet dramatists and playwrights


'Abd ul Jalil (sometimes called Selma in older sources) was the last king in the Duguwa dynasty of the Kanem Empire. His short rule lasted from approximately 1081 until 1085, when he was overthrown by Muslim followers of Hummay, the first Muslim king of the Sefuwa dynasty.

References

Rulers of the Kanem Empire
11th-century monarchs in Africa


International Fetish Day is a day supporting the BDSM community. It originated in the United Kingdom as National Fetish Day and was first held on 21 January 2008. The first International Fetish Day was held on 16 January 2009 (the third Friday of the year). The main purpose of International Fetish Day is to increase awareness and support of the fetish community, whilst also opposing the UK law criminalizing possession of "extreme pornography". It is also designed to encourage members of the community to be more open about their sexuality.

National Fetish Day
National Fetish Day was first celebrated in the United Kingdom on 4 September 2008. However, International Fetish Day has taken over from it.

Perverts Wear Purple
On National Fetish Day, one of the main aspects is that members of the community wear an item of purple clothing as a sign that they are a member, in an event known as "Perverts Wear Purple". The main benefit of this act is that it indicates that someone is a member of the community whilst being "Vanilla" at the same time. Purple is a colour widely used in BDSM circles. The main website says that, "By joining this fun 'National Fetish Day – Perverts Wear Purple' event, you as an individual will be joined by fellow community people all over the country in saying 'It's ok to enjoy what I enjoy' without damaging your 'vanilla' identity or integrity." There has been contention around the slogan 'Perverts Wear Purple' primarily to do with the fact that many in the BDSM community distance themselves from the 'pervert' label. Others in the community feel that using the word 'Pervert' is a useful reclaiming.

MP Ronnie Campbell
The Labour Member of Parliament for Blyth Valley, Ronnie Campbell, accidentally gave his support to National Fetish Day, because he misunderstood the word "Fetish" and was not aware of the "Perverts Wear Purple" slogan. A local newspaper, the Sunday Sun interviewed Campbell about his supposed support for the event by wearing purple. Campbell said, "I thought a fetish was a worry, like worrying about backing the right horse."

One of the people who publicised National Fetish Day, known as "Pierced Knight", claimed that,
I received an email from Carol Delaney, the secretary to Ronnie Campbell, Labour MP for Blyth Valley. She confirmed that Mr Campbell will be supporting this national day of awareness on 21st January. Using the tag line of 'Perverts Wear Purple' those that support this day will be wearing about their person something that is purple, like a shirt, a tie, a skirt, a hair band.

Campbell wrote a letter of complaint to the Sunday Sun, claiming that they had been making him look stupid by "twisting and turning" the meaning of what he had been saying. He wrote that, "I would never have agreed to support anything that had the title 'Perverts wear Purple' and I do not imagine any other Member of Parliament would either."

The Sunday Sun published a response saying,
If you hadn't misunderstood the word 'fetish' and backed National Fetish Day in the first place, we wouldn't have had a story. We did not twist anything and contacted you four times to clarify certain points. In fact, you were still backing National Fetish Day — saying you would wear your purple tie or shirt — until our final call when we pointed out the event slogan was 'perverts wear purple'. Imagine the story we could have written if we hadn't done this? This paper respects you as a Labour MP with an independent voice. However, this doesn't stop us writing stories when you drop yourself in it.

The first International Fetish Day was held on 16 January 2009. In the United Kingdom, the day attracted some media coverage because of the forthcoming ban on extreme pornography, coming into force on 26 January 2009. Symon Hill wrote in The Guardian that:

People with certain fetishes now face the prospect of becoming victims of the government's sustained assault on civil liberties. In a knee-jerk piece of headline-grabbing, ministers have introduced a law on "extreme pornography" which comes into force this month. Rather than targeting the exploitative, abusive and bullying elements of the pornography industry, the law is aimed at sadomasochistic images regardless of the context. So low is the barrier that if taken literally it could lead to a couple who take a photo of their consensual (and legal) sexual activity being arrested for possession of that photo.

See also
 Spirit Day

References

External links
International Fetish Day Homepage
The Guardian Comment is Free - International Fetish Day is something we can all celebrate

BDSM organizations
Sexual fetishism
Civil awareness days
January observances
Unofficial observances
Holidays and observances by scheduling (nth weekday of the month)


Cervières may refer to the following places in France:

 Cervières, Hautes-Alpes, a commune in the department of Hautes-Alpes
 Cervières, Loire, a commune in the department of Loire


Cervières is a commune in the Hautes-Alpes department in southeastern France.

The village lies at the foot of the Col d'Izoard, which is often on the route of the Tour de France and Giro d'Italia.

Population

See also
Communes of the Hautes-Alpes department
 Pic de Rochebrune
 Pic de Petit Rochebrune

References

Communes of Hautes-Alpes
Hautes-Alpes communes articles needing translation from French Wikipedia


Neuronal protein 3.1 is a protein that in humans is encoded by the NREP gene. It is highly expressed in the brain.

References

External links

Further reading


Haidao Suanjing (; The Island Mathematical Manual) was written by the Chinese mathematician Liu Hui of the Three Kingdoms era (220–280) as an extension  of chapter 9 of The Nine Chapters on the Mathematical Art.
During the Tang Dynasty, this appendix was taken out from The Nine Chapters on the Mathematical Art as a separate book, titled Haidao suanjing
(Sea Island Mathematical Manual), named after problem No 1 "Looking at a sea island." In the time of the early Tang dynasty, Haidao Suanjing was selected into one of The Ten Computational Canons as the official mathematical texts for imperial examinations in mathematics.

Content

This book contained many practical problems of surveying using geometry.  This work provided detailed instructions on how to measure distances and heights with tall surveyor's poles and horizontal bars fixed at right angles to them. The units of measurement were
 1 li = 180 zhang = 1800 chi,
 1 zhang = 10 chi = 100 cun,
 1 bu (step) = 6 chi,
 1 chi = 10 cun.

Calculation was carried out with place value decimal Rod calculus.

Liu Hui used his rectangle in right angle triangle theorem as the mathematical basis for survey. The setup is pictured on the right. By invoking his "in-out-complement" principle, he proved that the area of two inscribed rectangles in the two complementary right angle triangles have equal area, thus

Survey of sea island

Now we are surveying a sea island. Set up two 3-zhang poles at 1000 steps apart; let the two poles and the island be in a straight line. Step back from the front post 123 steps. With eye on ground level, the tip of the pole is on a straight line with the peak of island. Step back 127 steps from the rear pole. Eye on ground level also aligns with the tip of pole and tip of island. What is the height of the island, and what is the distance to the pole?

Answer: The height of the island is 4 li and 55 steps, and it is 102 li and 150 steps from the pole.

Method: Let the numerator equal to the height of pole multiplied by the separation of poles, let denominator be the difference of offsets, add the quotient to the height of pole to obtain the height of island.

As the distance of front pole to the island could not be measured directly, Liu Hui set up two poles of same height at a known distance apart
and made two measurements. The pole was perpendicular to the ground, eye view from ground level when the tip of pole was on a straight line sight with the peak of island, the distance of eye to the pole was called front offset = , similarly, the back offset = , difference of offsets = .

Pole height  chi
Front pole offset  steps
Back pole offset  steps
Difference of offset =
Distance between the poles =
Height of island =
Disttance of front pole to island =

Using his principle of inscribe rectangle in right angle triangle for  and , he obtained:
Height of island

Distance of front pole to island .

Height of a hill top pine tree

A pine tree of unknown height grows on the hill.  Set up two poles of 2 zhang each, one at front and one at the rear 50 steps in between. Let the rear pole align with the front pole. Step back 7 steps and 4 chi, view the tip of  pine tree from the ground till it aligns in a straight line with the tip of the pole. Then view the tree trunk, the line of sight intersects the poles at 2 chi and 8 cun from its tip . Step back 8 steps and 5 chi from the rear pole,  the view from ground also aligns with tree top and pole top.  What is the height of the pine tree, and what is its distance from the pole ?

Answer: the height of the pine is 12 zhang 2 chi 8 cun, the distance of mountain from the pole is 1 li and (28 + 4/7) steps.

Method: let the numerator be the product of separation of the poles and  intersection from tip of pole, let the denominator be the difference of offsets. Add the height of pole to the quotient to obtain the height of pine tree.

The size of a square city wall viewed afar

We are viewing from the south a square city of unknown size. Set up an east gnome and a west pole, 6 zhang apart, linked with a rope at eye level. Let the east pole aligned with the NE and SE corners. Move back 5 steps from the north gnome, watch the NW corner of the city, the line of sight intersects the rope at 2 zhang 2 chi and 6.5 cun from the east end. Step back northward 13 steps and 2 chi, watch the NW corner of the city, the line of sight just aligns with the west pole.  What is the length of the square city, and what is its distance to the pole?

Answer: The length of the square city is 3 li, 43 and 3/4 steps; the distance of the city to the pole is 4 li and 45 steps.

The depth of a ravine (using hence-forward cross-bars)

The height of a building on a plain seen from a hill

The breadth of a river-mouth seen from a distance on land

The depth of a transparent pool

The width of a river as seen from a hill

The size of a city seen from a mountain

Studies and translations
The 19th century British Protestant Christian missionary Alexander Wylie in his article "Jottings on the Sciences of Chinese Mathematics" published in North China Herald 1852, was the first person to introduce Sea Island Mathematical Manual to the West. In 1912, Japanese mathematic historian Yoshio Mikami published The Development of Mathematics in China and Japan, chapter 5 was dedicated to this book. A French mathematician translated the book into French in 1932. In 1986 Ang Tian Se and Frank Swetz translated Haidao into English.

After comparing the development of surveying in China and the West, Frank Swetz concluded that "in the endeavours of mathematical surveying, China's accomplishments exceeded those realized in the West by about one thousand years."

References

Chinese mathematics
Mathematics manuscripts


Copine-6 is a protein that in humans is encoded by the CPNE6 gene.

This gene encodes a brain-specific member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains, and one von Willebrand factor A domain. It may have a role in synaptic plasticity.

References

External links

Further reading


Ras-related protein Rab-33A is a protein that in humans is encoded by the RAB33A gene.

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is GTP-binding protein and may be involved in vesicle transport.

References

Further reading


Châteauvieux may refer to the following places in France:

 Châteauvieux, Hautes-Alpes, a commune in the department of Hautes-Alpes
 Châteauvieux, Loir-et-Cher, a commune in the department of Loir-et-Cher
 Châteauvieux, Var, a commune in the department of Var
 Châteauvieux-les-Fossés, a commune in the department of Doubs

People with the name Châteauvieux:
 Michel Lullin de Chateauvieux (1695-1781), Swiss author and experimenter on agriculture
 Michel Lullin de Chateauvieux (1754 - 1802), Swiss agronom, and grandson of Michel Lullin de Chateauvieux (1695-1781)
 Armand-François Chateauvieux (1770–?), dramatist and playwright


Transmembrane 9 superfamily member 2 is a protein that in humans is encoded by the TM9SF2 gene.

References

Further reading


Châteauvieux (; ) is a commune in the Hautes-Alpes department in southeastern France.

Population

See also
Communes of the Hautes-Alpes department

References

Communes of Hautes-Alpes


Immunoglobulin superfamily, member 2 (IGSF2) also known as CD101 (Cluster of Differentiation 101), is a human gene.

See also
 Cluster of differentiation

References

Further reading

External links

Clusters of differentiation


Patrick Dolan Critton (born 1947) is a former teacher from Mount Vernon, New York and the first successful aircraft hijacker in Canada.

Background
On December 26, 1971, Critton boarded Air Canada Flight 932, a DC-9, in Thunder Bay, Ontario bound for Toronto. Armed with a handgun and a grenade, he demanded the plane to fly to Havana, Cuba. At the time of the incident, Critton mistakenly thought he was a fugitive in New York City for a series of crimes, including bank robbery. He had fled to Canada, where he continued a life of crime.

He released all passengers in Toronto on his way to Havana and after he deplaned in Havana, the plane returned to Toronto safely with the crew members onboard. No injuries or casualties were caused during the hijacking.

Canada did not have an extradition agreement with Cuba regarding hijacking at the time. After arriving in Cuba, Critton served an 8-month prison sentence. Following his sentence, he first worked in the sugar cane industry in Cuba. Two years later, he moved to Tanzania, where he became a teacher. He later married and had two children before returning to the United States in 1994, feeling safe from the time passed since the hijacking.

Critton remained a fugitive until 2001, when he was found by a Canadian detective through a Google search, which at that time produced a single hit with his name that revealed the location where he was teaching. The one hit was a March 2001 article describing his mentoring of black youth in New York City.

Capture and aftermath
Critton was arrested on September 10, 2001 after nearly 30 years. Fingerprints on a ginger ale can found on the plane linked Critton to the hijacking. Canadian prosecutors, in order to avoid prejudicing the jury, based on the views of the recent September 11 attacks, which had happened the day after Critton was arrested, portrayed Critton to jurors not as a terrorist, but as a kidnapper and robber whose motivation was to gain the flight to Cuba.

Critton received a five-year prison sentence for the crimes. He was released in June 2003 after 1 year and 10 months and deported to the United States.

References

American bank robbers
American expatriates in Cuba
American people imprisoned abroad
Fugitives wanted by the United States
Hijackers
Living people
People from Mount Vernon, New York
Place of birth missing (living people)
Prisoners and detainees of Cuba
Prisoners and detainees of the United States federal government
1947 births


Belgium Park may refer to:

 Belgium Park, in the main campus of Mekelle University, Ethiopia
 Nickname of Monaghan United F.C., a soccer club in Ireland


The Stieglitz rearrangement is a rearrangement reaction in organic chemistry which is named after the American chemist Julius Stieglitz (1867–1937) and was first investigated by him and Paul Nicholas Leech in 1913. It describes the 1,2-rearrangement of trityl amine derivatives to triaryl imines. It is comparable to a Beckmann rearrangement which also involves a substitution at a nitrogen atom through a carbon to nitrogen shift. As an example, triaryl hydroxylamines can undergo a Stieglitz rearrangement by dehydration and the shift of a phenyl group after activation with phosphorus pentachloride to yield the respective triaryl imine, a Schiff base.

In general, the term "Stieglitz rearrangement" is used to describe a wide variety of rearrangement reactions of amines to imines. Although, it is generally associated with the rearrangement of triaryl hydroxylamines, that are well-reported in the academic literature, Stieglitz rearrangements can also occur on alkylated amine derivatives, haloamines and azides as well as other activated amine derivatives.

General mechanism and relatedness to the Beckmann rearrangement

The Stieglitz rearrangement's reaction mechanism and the products and starting materials involved make it closely related to the Beckmann rearrangement, which can be used for the synthesis of carboxamides. Both rearrangement reactions involve a carbon to nitrogen shift, usually after electrophilic activation of the leaving group on the nitrogen atom. The main difference in the starting materials, however, is their saturation degree. While a Stieglitz rearrangement takes place on saturated amine derivatives with a σ-single bond, the typical starting material for a Beckmann rearrangement is an oxime (a hydroxylimine) with a C=N-double bond.
In a Beckmann rearrangement, the acid catalyzed carbon to nitrogen migration takes place on the oxime to yield a nitrilium ion intermediate. In principle, the first step of a Stieglitz rearrangement proceeds in an analogous way. However, after the generation of the positively charged iminium ion through the π-interaction between the nitrogen lone pair and the electron deficient carbon in the Stieglitz rearrangement, the pathways diverge. In the Stieglitz rearrangement, a charge-neutral state of the molecule can be achieved by dissociation of a proton. Alternatively, if the  starting material did not possess any amino protons, the neutral state can be achieved with an external reducing agent, such as sodium borohydride. It reduces the iminium ion intermediate to the corresponding saturated amine. In the Beckmann rearrangement such a proton is also missing and the stabilization of the intermediate proceeds via a nucleophilic addition of a water molecule, dissociation of a proton and tautomerism from the imidic acid to the carboxamide.

Variations
Although the original Stieglitz reaction is best known for the rearrangement of trityl hydroxylamines, there are several variations which include good leaving groups as N-substituents (such as halogens and sulfonates). Different reagents are commonly applied, depending on the exact nature of the substrate.

Stieglitz rearrangement of N-hydroxylated amines, N-alkoxylated amines and N-sulfonated amines

Stieglitz rearrangement of N-hydroxylated amines
For the rearrangement of trityl hydroxylamines, Lewis acids such as phosphorus pentachloride (PCl5) , phosphorus pentoxide (P2O5)  or boron trifluoride (BF3) can be used. They function as electrophilic activators for the hydroxyl group by increasing the quality of the leaving group.
For example, when using PCl5 as a reagent, the trityl hydroxylamine is first transformed into the activated intermediate via a nucleophilic substitution. The generated intermediate can then undergo rearrangement by the migration of the phenyl group and dissociation of the phosphorus(V) species to form N-phenyl benzophenone imine.

Stieglitz rearrangement of N-alkoxylated amines
Additionally to N-hydroxy trityl amines, rearrangements in N-alkoxy trityl amines are also possible. However, those reactions are known for their intrinsically low yields. For example, N-benzyloxy substituted trityl amine can undergo a Stieglitz rearrangement in the presence of phosphorus pentachloride (160 °C, 40% yield) or with BF3 as a reagent (60 °C, 29% yield). In the latter case, BF3 acts as a Lewis acid in the electrophilic activation of the benzylic oxygen to allow for a nucleophilic attack on the adjacent nitrogen atom.

Stieglitz rearrangement of N-sulfonated amines
Stieglitz rearrangements also readily proceed with active sulfonates as a leaving group. N-sulfonated amines can be obtained from the respective hydroxylamines and suitable sulfonation reagents. For example, Herderin et al. synthesized their secondary hydroxylamine (starting material in the rearrangement shown below) by subjecting the respective hydroxylamine to tosyl chloride and sodium hydroxide in acetonitrile.

The Stieglitz rearrangement is especially reactive in the case of bridged bicyclic N-sulfonated amines as starting materials, where mild conditions are sufficient for an efficient reaction to take place. For example, the rearrangement of the bicyclic N-tosylated amine proceeds readily in aqueous dioxane at room temperature. However, the respective imine is not formed in this case, presumably due to the strain that would thermodynamically disfavor such a structure, bearing a double bond at a bridgehead atom (Bredt's rule). Instead, the tosylate is nucleophilically added at the geminal position of the nitrogen via an attack on the iminium ion.

Stieglitz rearrangement of azides
Stieglitz rearrangements can also proceed on organic azides with molecular nitrogen as a good leaving group. Those reactions proceed comparably to steps of the Schmidt reaction, by which carboxylic acids can be transformed into amines through the addition of hydrazoic acid under acidic aqueous conditions.
The Stieglitz rearrangement of azides generally profits from a protonic or thermal activation, which can also be combined. In both cases, molecular nitrogen is set free as a gas in an irreversible step. It has been suggested that the rearrangement, after the dissociation of the N2 molecule, proceeds over a reactive nitrene intermediate. These intermediates would be quite similar to those that have been proposed to be key intermediates in the rearrangement reactions named after Hofmann and Curtius, but have since been considered unlikely.
When subjecting the azide to a Brønsted acid, the protonation of the azide activates the basal nitrogen and lowers the bond strength to the adjacent one, so that the dissociation and expulsion of molecular nitrogen is eased. After the rearrangement the proton can then dissociate from the iminium ion to yield the imine.

An alternative way for the production of protonated organic azides is the nuclophilic addition of hydrazoic acid to a carbocations, which can then also undergo Stieglitz rearrangements.

Stieglitz rearrangement of N-halogenated amines

The Stieglitz rearrangement of N-halogenated amines can be observed for chlorine and bromine substituted amines, often in combination with an organic base, such as sodium methoxide. The need for a base is generally affiliated with the need for a deprotonation of the amine.

However, there also have been reported examples of base-free Stieglitz rearrangements of N-halogenated amines. An example for that can be found in the total synthesis of (±)-lycopodine by Paul Grieco et al. There, a ring formation takes place by a rearrangement on a secondary haloamine by subjecting it to silver tetrafluoroborate. AgBF4 is known to act as a source of Ag+ ions that can facilitate the dissociation of halides from organic molecules, with the formation of the respective silver halide as a driving force. The desired product is then obtained by reduction with sodium cyanoborohydride, a mild reducing agent which is commonly employed in the reduction of imines to amines.

Stieglitz rearrangement of lead tetraacetate-activated amines
It was also observed, that the addition of lead tetraacetate can facilitate the Stieglitz rearrangement of amine derivatives. After the formation of the activated amine derivative intermediate by coordination to the lead center, the following rearrangement again proceeds via migration of the aromatic group under formation of a C–N bond, dissociation of lead and the deprotonation of the resulting iminium ion.

See also
 Beckmann rearrangement
 Curtius rearrangement
 Dakin oxidation
 Schmidt reaction

References

Rearrangement reactions
Name reactions


Rules derby (or Sheffield derby) is a football derby played in Sheffield, England between Sheffield F.C. and Hallam F.C. It was first played on 26 December 1860 and is the oldest football fixture in the world. The name refers to the fact that the fixture was originally played under the Sheffield Rules.

History
The first match was played at Hallam's home ground, Sandygate Road and resulted in a Sheffield victory by two goals to nil. The teams competed in the first ever football match at Bramall Lane.

The derby is currently not a regular fixture as Sheffield are currently in the NPL Division One South, while Hallam are in the NCEL Division 1, two tiers below, however, the teams do regularly meet in pre-season friendlies and occasionally local FA matches.  The last meeting between the two sides was a 3–2 win for Sheffield on 9 October 2012 in the Senior Cup at the Coach and Horses Ground, Dronfield.

References

Sport in Sheffield
Football derbies in England
Hallam F.C.
Sheffield F.C.
Football in South Yorkshire


L'Épine may refer to the following places in France:

 L'Épine, Hautes-Alpes, a commune in the department of Hautes-Alpes
 L'Épine, Marne, a commune in the department of Marne
 L'Épine, Vendée, a commune in the department of Vendée
 L'Épine-aux-Bois, a commune in the department of Aisne
 Chaîne de l'Épine, a mountain ridge in the department of Savoie, near Chambéry


Tony Mark McKnight (born June 29, 1977) is a retired Major League Baseball pitcher. He played during two seasons at the major league level for the Houston Astros and Pittsburgh Pirates. He was drafted by the Astros in the 1st round (22nd pick) of the  amateur draft. McKnight played his first professional season with their Rookie league Gulf Coast Astros in 1995, and his last with the Los Angeles Dodgers' Triple-A Las Vegas 51s in .

On July 31, 2001, the Astros traded McKnight to the Pirates for Mike Williams.

Prior to the 2017 college baseball season, McKnight began volunteering as an assistant coach for the baseball team at Texas A&M University–Texarkana.

References

External links

1977 births
Living people
Baseball players from Arkansas
Gulf Coast Astros players
Houston Astros players
Jackson Generals (Texas League) players
Kissimmee Cobras players
Las Vegas 51s players
Major League Baseball pitchers
Nashville Sounds players
New Orleans Zephyrs players
Pittsburgh Pirates players
Quad Cities River Bandits players
Round Rock Express players
Texas A&M–Texarkana Eagles baseball coaches


ATP-dependent DNA helicase Q5 is an enzyme that in humans is encoded by the RECQL5 gene.

Interactions

RECQL5 has been shown to interact with EEF1G.

References

Further reading


L'Épine (; ) is a commune in the Hautes-Alpes department in southeastern France.

Population

See also
Communes of the Hautes-Alpes department

References

Communes of Hautes-Alpes


Endothelin-converting enzyme-like 1 is a protein that in humans is encoded by the ECEL1 gene.

This gene encodes a member of the neutral endopeptidase (NEP)-related family. It is expressed specifically in the nervous system. The gene disruption in mouse embryonic stem cells results in neonatal lethality due to respiratory failure shortly after birth. Based on the specific expression of this gene and the phenotype of the gene deficiency in mouse embryos, it is suggested that the protein encoded by this gene play a critical role in the nervous regulation of the respiratory system.

References

Further reading


Esparron may refer to the following places in France:

 Esparron, Hautes-Alpes, a commune in the department of Hautes-Alpes
 Esparron, Haute-Garonne, a commune in the department of Haute-Garonn
 Esparron, Var, a commune in the department of Var


Esparron () is a commune in the Hautes-Alpes department in southeastern France.

Population

See also
Communes of the Hautes-Alpes department

References

Communes of Hautes-Alpes


Interleukin 27 receptor, alpha is a subunit of the interleukin-27 receptor. IL27RA is its human gene.

Function

In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.

Interactions

Interleukin 27 receptor, alpha subunit has been shown to interact with STAT1.

References

Further reading


Montclus is a commune in the Hautes-Alpes department in southeastern France.

Population

See also
Communes of the Hautes-Alpes department

References

Communes of Hautes-Alpes


GPI mannosyltransferase 3 is an enzyme that in humans is encoded by the PIGB gene.

This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene is thought to encode a member of a family of dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases.

References

Further reading


A disintegrin and metalloproteinase with thrombospondin motifs 3 is an enzyme that in humans is encoded by the ADAMTS3 gene. The protein encoded by this gene is the major procollagen II N-propeptidase.

Structure

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase.

Function

Because of the high similarity to ADAMTS2, the major substrate of ADAMTS3 had been erroneously assumed to be procollagen II. However, ADAMTS3 appears largely irrelevant for collagen maturation but instead is required for the activation of the lymphangiogenic growth factor VEGF-C. Hence, ADAMTS3 is essential for the development and growth of lymphatic vessels. The proteolytic processing of VEGF-C by ADAMTS3 is regulated by the CCBE1 protein.

ADAMTS3 has been shown to cleave reelin, a protein that regulates the proper lamination of the brain cortex and whose signal activity is found to be disrupted in a number of neuropsychiatric conditions.

Clinical significance

A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues.

Some hereditary forms of lymphedema are caused by mutations in ADAMTS3.

References

Further reading

External links
 The MEROPS online database for peptidases and their inhibitors: M12.220

ADAMTS


Montjay may refer to the following places in France:

 Montjay, Hautes-Alpes, a commune in the department of Hautes-Alpes
 Montjay, Saône-et-Loire, a commune in the department of Saône-et-Loire


Montjay () is a commune in the Hautes-Alpes department in southeastern France.

Population

See also
Communes of the Hautes-Alpes department

References

Communes of Hautes-Alpes


Eukaryotic translation elongation factor 1 epsilon-1 is a protein that in humans is encoded by the EEF1E1 gene.

References

Further reading

External links


Montmaur may refer to the following places in France:

 Montmaur, Hautes-Alpes, a commune in the department of Hautes-Alpes
 Montmaur, Aude, a commune in the department of Aude


Etoposide-induced protein 2.4 homolog is a protein that in humans is encoded by the EI24 gene.

This gene has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The protein encoded by this gene contains six putative transmembrane domains and may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in two transcript variants encoding different isoforms.

References

Further reading


Montmaur () is a commune in the Hautes-Alpes department in southeastern France.

Population

See also
Communes of the Hautes-Alpes department

References

Communes of Hautes-Alpes


Neva () was the British merchant ship Thames, launched in 1801, that the Russians bought in 1803, and renamed Neva. She participated in two trips to the Far East, the first of which was the first Russian circumnavigation of the world. She was wrecked in January 1813.

Thames
Thames was a -long, three-masted sailing ship of 370 tons burthen, built in Britain in 1801.

Russian career
In 1802, Imperial Russian Navy officer Yuri Lysianskyi travelled to England where he bought two vessels, Thames and Leander, on his own account. Both ships left England for the Baltic in May 1803, docking at Kronstadt on 5 June. Czar Alexander I renamed Thames to Neva, after the river, and Leander to Nadezhda ("Hope"). The two vessels sailed in 1803 on a voyage that would become the first Russian circumnavigation of the world. For the voyage Neva carried 14 cannon and a crew of 43 men under Lysianskyi's command. The commander of the expedition was Admiral Ivan Fyodorovich Kruzenstern, in Nadezhda. Although the vessels were armed, as were many merchant vessels at the time, they were never commissioned into the Russian navy.

Neva played a key role in the 1804 battle of Sitka when the Russians recaptured Fort St Archangel Mikhail and the town from the Tlingit, who had captured it in 1802. In 1804, Alexandr Baranov, general manager of the Russian American Company, had failed in his attempt to recapture the Fort with a force of 120 Russians in four small vessels and 800 Aleuts in 300 baidarkas (leather canoes). Baranov returned to Sitka Sound in late September 1804 aboard Neva. Neva was accompanied by Ermak and two other smaller, armed sailing ships, manned by 150 promyshlenniks (fur traders), along with 400–500 Aleuts in 250 baidarkas. This force succeeded in returning the region to Russian control. Reportedly, afterwards a shaman placed a curse on Neva and all on her in retribution; some eight years later she wrecked.

In 1805 Neva discovered Lisianski Island and the surrounding Neva Shoals by running aground there. Lysianskyi reported that the island was of little interest, except insofar as its surrounding reefs and shoals posed a threat to passing vessels.  Lisyanski was the first to describe the Hawaiian monk seal, which he observed on the island that now bears his name.

In 1805–6, Neva carried a cargo of 150,000 fur seal pelts to China. There she sold them for tea, chinaware and nankeen, which she carried back to Russia.

In 1806–7, Neva made a second trip to the Pacific Ocean, this time under the command of Captain lieutenant Ludwig von Hagemeister. Hagemeister would later become Chief Manager of the Russian American Company.

Neva left Kronstadt on 2 November 1806 and reached Salvador, Brazil on 10 January 1807. She did not leave there until 9 March. Although Hagemeister had originally planned to travel via Cape Horn, it was too late in the season to do so, so he sailed to Port Jackson instead for "wood and water".

In June, Neva became the first Russian ship to reach the Australian mainland when she visited the new British colony at Port Jackson, modern Sydney, on 4 June 1806.

Fate
Neva left Okhotsk, Russia in August 1812 carrying 75 people and a shipment that included guns, furs, and some religious treasures. After enduring three months of storms, sickness and water shortages, Neva arrived in Alaska's Prince William Sound. The crew pushed eastward toward Sitka; near Kruzof Island, the ship hit rock and sank, on 9 January 1813. Thirty-two crew members died in the wreck; 28 survivors of the wreck made it to shore, two of whom died before rescuers arrived some three weeks later. The sites of the wreck and the survival camp have been found on Kruzof Island.

The site of the camp is a little inland from the beach. In the 203 years since Neva wrecked, the shoreline has risen some 11 feet due both to movement of tectonic plates because the reduction of weight on the land due to melting of glaciers is causing geologic rebound.  At the time of the wrecking, the campsite was at the beach.

In addition to crew members, many passengers died, including Terentii Stepanovich Bornovolokov, who was to replace Alexandr Baranov as Governor of the Russian–American Company. The financial loss to the Russian–American Company amounted to more than 250,000 rubles. It was the second gravest marine catastrophe in the history of Russian America, after  (or Feniks) was lost at sea in 1799 with all hands and passengers, including Joasaph Bolotov, and cargo, for a total financial loss of 622,328 rubles.

Commemorative coins

In 1993 Russia issued four coins to commemorate the first Russian voyage around the world. One was a 150-rouble platinum coin showing both Nadezhda and Neva on the reverse. Two were 25-rouble palladium coins, one for Nadezhda and one for Neva, and the final one was a 3-rouble coin with both ships and a map of the voyage.

See also
 European and American voyages of scientific exploration

Notes

Citations

References
 Barratt, Glynn (1987). The Russian Discovery of Hawai'I: The Ethnographic and Historic Record. Editions Limited. .
Khlebnikov, K.T. (1973) Baranov, Chief Manager of the Russian Colonies in America. (Kingston: The Limestone Press).
 Massov, Aleksandr (2006). "The visit of the Russian sloop Neva to Sydney in 1807: 200 years of Russian–Australian contacts." Australian Slavonic and East European Studies, Vol. 20, 1–2. School of Languages and Comparative Cultural Studies, The University of Queensland. ISSN 0818-8149.
 Postnikov, A. (2002). Thesis. S.I. Vavilov Institute of the History of Science and Technology of the Russian Academy of Sciences, Moscow, Russia —"The first Russian round the world voyage and its influence on exploration and development of Russian America" accessed 25 September 2005.
Rosen, Yereth (5 March 2017), " Archaeologists say they've found the campsite used by survivors of legendary 'doomed' ship". Alaska News Dispatch.

1801 ships
Maritime incidents in 1812
Russian-American Company
Age of Sail merchant ships
Merchant ships of the United Kingdom
Shipwrecks of the Alaska coast


A color suite (also called a color bay, telecine suite, or color correction bay) is the control room for color grading video in a post-production environment.

Technology and specifications
The video source could be from: a telecine, a video tape recorder (VTR), a motion picture film scanner, virtual telecine or a direct-to-disk recording (DDR) or the older system called a film chain. A high end broadcast color suite may use a Da Vinci Systems or Pandora International color corrector. If a VTR is the source for the video the room is often called a tape to tape suite. Many suites are designed to operate as a telecine suite or a tape to tape suite by changing the configuration of the suite. The operator of the suite is usually called a Colorist. If a telecine is the source this is called a Film to Tape operation. A color suite may use one video standard or be able to change configuration to a number of standards like: high-definition video, NTSC, or PAL or a DI workflow. Color suites are sometime placed in digital cinema movie theaters with a video projector for color correction to that display format.

The suite room will also have equipment in the production control room for monitoring the video signal such a video monitor, waveform monitor and vectorscope.

The suite may have an either a non-linear editing system (NLE) or linear editing system to control the source and record device. This may be internal to the color grading device, as in a Pandora's Pogle or Da Vinci's 2k or external, as in Da Vinci's TLC (telecine controller).

A vision mixer may also be in the suite for monitoring different video sources or for simple or special effects in the video. A character generator is sometime used also for titling and subtitle.

The suite may have equipment to read, log and insert into the video Kodak's Keykode. Keykode is bar coding that is placed at regular intervals on negative films to aid in identifying and counting of film frames. Evertz, Aaton and ARRI are three types of readers for telecine use.

The suite may or may not have audio post production equipment. This would be to monitor and if needed sync up the program audio to the video source if the sound was not on the film. An audio mixing console and other audio equipment such as effects devices may also be in the suite. The audio may be from the film soundtrack. The term MOS is used, on a slate, when a scene is filmed without sync sound or any sound. A clapperboard slate is used at the start and sometime at the end of scene to mark particular takes recorded during a production.

Other equipment that may be used in the suite are: digital still store\Frame grabber to store references frames, noise reducer to reduce film grain/dirt and video noise; video router and audio router.

The telecine, VTRs and some of the larger equipment are often placed in a central apparatus room or machine room and are interconnected through Cable trays or raised floor to the color suite by patch panels, coaxial cables, computer network and multicore cables.

Some color suites are at video post production facilities that rent them by the hour for the transfer of TV commercials, documentaries and movies.
These color suites would have a client area behind the colorist. With the client present this would be called a supervised session.

See also
 Test film
 3D LUT
 Cintel, telecine equipment.
 Color motion picture film
 Da Vinci Systems
 Pandora International
 Digital intermediate
 Display resolution
 Faroudja, inventors of reverse telecine technologies.
 Film recorder
 Film restoration
 Film-out
 Gamma correction
 Hard disk recorder
 HDTV blur Factors causing HDTV Blur
 Image scanner
 Telecine (piracy), an unauthorized copy of a film created with a telecine.
 Telerecording (UK)
 Television

References
Technicolor’s Post production Facility, Technicolor, October 31, 2006
Nice Shoes Adds Fourth Telecine Suite, creativemac.digitalmedianet.com, November 1, 2004
UCLA Film and Television Archive UCLA, visited January 15, 2008
Postworks Opens Fifth Telecine Suite, digitalmedianet.com, May 23, 2006
 Film Sound Terminology

Film and video technology
Television terminology


Montmorin may refer to the following people and places.

People
 Armand Marc, comte de Montmorin, French minister of foreign affairs and the navy under Louis XVI.

Places
 Montmorin, Hautes-Alpes, a commune in the department of Hautes-Alpes
 Montmorin, Puy-de-Dôme, a commune in the department of Puy-de-Dôme


Prolyl endopeptidase-like is an enzyme that in humans is encoded by the PREPL gene.

PREPL belongs to the prolyloligopeptidase subfamily of serine peptidases (Parvari et al., 2005).[supplied by OMIM]

References

Further reading


Montmorin (; Vivaro-Alpine: Montmaurin) is a former commune in the Hautes-Alpes department in southeastern France. On 1 July 2017, it was merged into the new commune Valdoule.

Population

See also
Communes of the Hautes-Alpes department

References

Former communes of Hautes-Alpes


Serpent Saints: The Ten Amendments is the ninth album by Swedish death metal band Entombed, released in June 2007. It was their last one before their two-year breakup from 2014 to 2016. It is the first album with bassist Nico Elgstrand and drummer Olle Dahlstedt, as well as the band's first without longtime guitarist Uffe Cederlund. The album marks the final time to feature original vocalist LG Petrov before the band's breakup in 2014 and his death in 2021.

Even more than Morning Star, the album was largely considered a throwback to the band's traditional death metal roots, with the hard rock-influenced sections being eschewed almost entirely.

Track listing

Personnel
Lars-Göran Petrov – vocals
Alex Hellid – guitars
Nico Elgstrand – bass
Olle Dahlstedt – drums

References

Entombed (band) albums
2007 albums


RNA-binding protein 39 is a protein that in humans is encoded by the RBM39 gene.

Function

The protein encoded by this gene is an RNA binding protein and possible splicing factor. The encoded protein is found in the nucleus, where it colocalizes with core spliceosomal proteins. Studies of a mouse protein with high sequence similarity to this protein suggest that this protein may act as a transcriptional coactivator for JUN/AP-1 and estrogen receptors. Multiple transcript variants encoding different isoforms have been observed for this gene.

Interactions

RBM39 has been shown to interact with Estrogen receptor alpha, Estrogen receptor beta and C-jun.

References

Further reading


Serine/threonine-protein kinase LMTK1 (also known as Apoptosis-associated tyrosine kinase) is an enzyme that in humans is encoded by the (AATK) gene.

Structure and expression

The gene was identified in 1998. It is located on chromosome 17 (17q25.3) and is expressed in the pancreas, kidney, brain and lungs. The protein is composed of 1,207 amino acids.

Function

The protein contains a tyrosine kinase domain at the N-terminal end and a proline-rich domain at the c-terminal end.  Studies of the mouse homologue have indicated that it may be necessary for the induction of growth arrest and/or apoptosis of myeloid precursor cells. It may also have a role in inducing differentiation in neuronal cells.
Its suppressive role on melanoma development has been reported recently.

AATK is thought to indirectly inhibit the SPAK/WNK4 activation of the Na-K-Cl cotransporter.

References

Further reading

External links

Genes on human chromosome 17
Tyrosine kinase receptors


Valeri Semyonovich Frid (, 13 January 1922 – 7 September 1998) was a Soviet screenwriter. Most of his works were made together with Yuli Dunsky. Both of them were imprisoned in Gulag labor camps.

Filmography

Writer
 1991 Lost in Siberia
 1990 Death in Сinema
 1987 The Tale of the Painter in Love
 1984 And Then Came Bumbo
 1983 Every Tenth
 1983 Adventures of the Little Muk
 1982 The Story of the Voyages
 1981 Don't be Afraid, I'm with You
 1980 Air Crew
 1980 The Gadfly
 1979 The Adventures of Sherlock Holmes and Dr. Watson: Bloody Signature
 1979 The Adventures of Sherlock Holmes and Doctor Watson: Acquaintance
 1976 How Czar Peter the Great Married Off His Moor
 1976 The Widows
 1974 High Title / For the Life on Earth
 1973 High Title / I, Shapovalov T. P.
 1971 The Shadow
 1970 Shine, Shine, My Star
 1969 An Old, Old Tale
 1968 Bare et liv - historien om Fridtjof Nansen (Just One Life)
 1968 Two Comrades Were Serving
 1965 Once Upon a Time There Was an Old Man and an Old Woman
 1964 An Unthinkable Story
 1962 Seven Nannies
 1962 Sixteenth Spring
 1960 The Same Age
 1957 The Case at Mine Eight

Actor

 1998 Classicist
 1968 Two Comrades Were Serving
 1999 Chinese Tea-Set

References

External links

1922 births
1998 deaths
Soviet screenwriters
Male screenwriters
Academic staff of High Courses for Scriptwriters and Film Directors
People from Tomsk
20th-century screenwriters
Soviet dramatists and playwrights
Gulag detainees
Gerasimov Institute of Cinematography alumni
Recipients of the Nika Award


This is a list of students' associations in Ontario, Canada:

Universities

In addition to university-wide student unions that represent all students, or all students based on enrolment status (undergraduate, graduate, or part-time), there are some universities with faculty-specific student unions. These include Arts and Science Students’ Union (ASSU) at the University of Toronto and Arts and Science Undergraduate Society (ASUS) at Queen's University.

Federated Universities and Colleges
Federated universities and colleges are affiliated with larger institutions, but maintain their own autonomy and are governed as separate universities by their own provincial Acts.

Federated university student unions include:
 Laurentian University / Université Laurentienne:
Université de Hearst—Association des étudiantes et étudiants de l’Université de Hearst
 University of Ottawa / Université d'Ottawa:
Saint Paul University / Université Saint-Paul—Saint Paul University Student Association
 University of Toronto:
University of St. Michael's College—St. Michael's College Student Union
Trinity College—Trinity College Meeting
Victoria University—Victoria University Students’ Administrative Council
 University of Waterloo:
St. Jerome's University—Students' Union of St. Jerome's University
 University of Western Ontario:
Brescia University College—Brescia University College Students' Council
Huron University College—Huron Students' Council

OUSA
The undergraduate students' associations of Brock University, Laurentian University, McMaster University, Queen’s University, Trent University Durham Campus, the University of Waterloo, Wilfrid Laurier University, and the University of Western Ontario make up the Ontario Undergraduate Student Alliance.

CFS-Ontario
The Canadian Federation of Students—Ontario represents 35 student unions in Ontario.

Colleges

College Student Alliance (CSA)
The student associations of Cambrian, Centennial, Conestoga, Confederation, Durham, Fleming, Georgian, Northern, Sault, St. Clair, St. Lawrence colleges make up the College Student Alliance.

Secondary schools

References

See also
Canadian Alliance of Student Associations
Canadian Federation of Students
Ontario Undergraduate Student Alliance
College Student Alliance
List of Canadian students' associations


Maria Thereza Fontella Goulart (born August 23, 1936) is the widow of the 24th president of Brazil, João Goulart, and served as First Lady during his presidency from 1961 until 1964, when he was deposed by a military-led coup d'état.

Biography

Early life
Born in the interior of the state of Rio Grande do Sul, Goulart was the daughter of Italian immigrants Dinarte Fontella and Maria Júlia Pasqualotto, who gave birth alone on an isolated road when she was 15 years old. With her mother she learned Italian and with her maternal uncle she learned to ride and shoot - already mastering target shooting at age 8.

At the age of 5, Goulart moved in with her aunt Horaides Zambone in São Borja, to recover from anemia. Still at the age of 5 she was enrolled in the Getúlio Vargas School Group, but was expelled. She was then enrolled in an extremely strict school run by nuns, where she stayed for two years, until she was expelled.

Maria Tereza studied at the American Methodist College, a boarding school in Porto Alegre, where she stayed under the care of a cousin, where in school, his life was under strict rules. In the city of São Borja, she lived next door to João Goulart's house, whom she met personally at the age of fourteen. According to Maria Thereza herself, she was in charge of bringing correspondence to him at the request of Dinarte Dornelles (Getúlio Vargas' maternal uncle).

In Porto Alegre, at the house of her aunt América Fontella who was married to Spartacus Dornelles Vargas (Getúlio's brother), Maria Tereza met Leonel Brizola at the age of 12. She met João Goulart when at 13 years old and he, 31. Maria Thereza held her debutante ball, and Goulart was among the guests. As she said, she did not fall in love with her future husband at "first sight", because she didn't imagine that "she could date a person of her projection". Among Maria Thereza's cousins was the politician Yara Vargas, who later helped found the Democratic Labor Party (PDT).

Marriage and children

In 1955, when Maria Thereza finished her studies, she and Jango Goulart started dating. They got married in the following year when Maria Thereza was 16 and Jango was running for the vice presidency. At that time, there were separate elections for president and vice president in Brazil, and Jango would receive more votes than Juscelino Kubitschek, who was elected president. After her marriage, Maria Thereza became the sister-in-law of Leonel Brizola, who was married to Jango's sister Neusa.

In 1960, Jango was re-elected vice president, which allowed Maria Thereza to serve as Second Lady from 1956 to 1961, when Jânio Quadros resigned from the presidency. When her husband assumed office, Maria Thereza became the youngest First Lady in the history of Brazil, at just 21 years of age.

Maria Thereza and Jango had two children: the former congressman João Vicente and the historian Deize. When she served as Second Lady, her family lived in the Chopin Building, next to the Copacabana Palace in Rio de Janeiro. During the time she served as First Lady, she lived in the Granja do Torto in the then recently built capital Brasília. She lived in Palácio da Alvorada, the official residence, for six months, but preferred the Granja do Torto because she liked horse racing.

Life as First Lady

In August 1961, Maria Thereza and her children were guests in a Spanish hotel owned by a friend of the Goulart family, while her husband was on a diplomatic mission in the People's Republic of China. One day, at breakfast, she was told that Jânio Quadros had resigned and that her husband would become the new president. Shortly after, journalists started incessantly calling her room.

Quadros advised her to stay at the hotel until the situation with the military ministers, who refused to recognize Jango as the new president because of his connections with members of the Brazilian Communist Party and the Brazilian Socialist Party, was solved. Maria Thereza only returned to Brazil when her husband assumed the presidency.

As First Lady, Maria Thereza was responsible for the foundation of the headquarters of the Legião Brasileira de Assistência (Brazilian Legion of Aid) -- an organization founded in 1942 by then First Lady Darcy Vargas to help poor families—in Brasília. She hosted a large number of charitable events, being responsible for bringing members of the high society to participate in such events.

Maria Thereza chose to wear haute couture outfits to public events, and became a fashion icon, being compared to Jacqueline Kennedy and appearing on the covers of a large number of magazines. Her personal stylist was Dener Pamplona de Abreu. Prior to the coup, she was named one of the ten most beautiful women in the world by People magazine.

Life in exile
After the deposition of Jango on April 1, 1964 by the military, the Goulart family was forced to live in exile. Jango, Maria Thereza and their children lived in Uruguay. Later, Denise and João Vicente moved to London, while Jango and Maria Thereza went to Argentina, where Jango had business affairs. Jango died in the city of Mercedes on the night of December 6, 1976. The official version of his death is that he suffered a heart attack. This is uncertain as his body was not submitted for an autopsy and the attending physician wrote only the Spanish word enfermedad (sickness) as the causa mortis on his medical chart. He was buried in his native São Borja. Thirty thousand people attended his funeral, media coverage of which was censored by the military regime. Maria Thereza and her children were forbidden to return to Brazil until 1979's amnesty law.

Amnesty
On November 15, 2008, Maria Thereza and Jango received political amnesty from the Federal Government. The former First Lady would receive an indemnification of R$ 644,000 (around US$ 322,000) to be paid in pensions of R$5,425 (around US$2,712) per month, in compensation for Jango being prohibited from practicing his job as a lawyer. She also received an indemnification of R$100,000 (around US$50,000) for the 15 years when her family was forbidden to return to Brazil.

Film
Director Susanna Lira will make the film Vestida de Silêncio, whose production was scheduled to begin in 2021, which will examine the life story of João Goulart through the eyes of Maria Thereza.

Further reading
In 2019, the writer Wagner William released a biographical book about the former First Lady Maria Thereza Goulart.

References

|-

1936 births
People from São Borja
First ladies of Brazil
Second ladies of Brazil
Brazilian people of Italian descent
Living people
Brazilian Labour Party (historical) politicians


Montrond may refer to the following places in France:

 Montrond, Hautes-Alpes, a commune in the department of Hautes-Alpes
 Montrond, Jura, a commune in the department of Jura
 Montrond-le-Château, a commune in the department of Doubs
 Montrond-les-Bains, a commune in the department of Loire
 Saint-Amand-Montrond, a commune in the department of Cher


ČSD Class ES 499.1 is a  class of electric locomotives used primarily for passenger trains in Czech Republic and Slovakia. Now classified as Class 363, these locomotives passed to České dráhy, rail operator in the Czech Republic, and to ZSSK, rail operator in Slovakia. Class 363 is also used by ČD Cargo and ZSSK Cargo for hauling freight trains.

ES 499.1 locomotives operate both on the 3,000 V DC system and the 25 kV 50 Hz AC system.

History
In 1980 Škoda produced ES 499.1001 and 1002 as prototype locomotives for the replacement of the existing ČSD fleet. Production series locomotives started to be delivered in 1984. Two single system derivatives were also created S 499.2 (AC) and E 499.3 (DC). During 1990 further development to run at 140 km/h lead to the ČD Class 362, but an order for 30 locos was canceled due to financial problems. Some ČD Class 363 and ŽSR Class 363 locomotives are being rebuilt as 362s. Since 2011, they have also been operated with control trailers.

Power regulation
In 1980, these locomotives were the world's first multisystem locomotives with power thyristor pulse regulation. This regulation has minimal losses compared to older resistive regulation with much higher losses. This gave the locomotive its characteristic sound in three frequencies (the first is 33,3 Hz, the second is 100 Hz and the third is 300 Hz) when locomotive accelerating.

Usage
363s are currently used to haul these services
ČD
Prague - Břeclav
Prague - České Budějovice
Prague - Plzeň
Ústí nad Labem - Cheb
Břeclav - Petrovice u Karviné
Brno - Bohumín
Brno - Olomouc (- Šumperk)
ZSSK
Bratislava - Žilina - Košice

Disposition

As of June 23, 2008, 12 363s remained in service with ZSSK, 23 with ZSSK Cargo, 63 with ČD and 47 with ČD Cargo.

See also
List of České dráhy locomotive classes

References

External links

Lokomotivní řada 363 ČD (ES 499.1 ČSD) in Czech
Prototypy.cz about the locomotive in Czech
VLAKY.NET forum
Czech and Slovak Railway Group in English
video of this locomotive class

25 kV AC locomotives
3000 V DC locomotives
Bo′Bo′ locomotives
Electric locomotives of Czechoslovakia
Electric locomotives of Slovakia
Electric locomotives of the Czech Republic
Railway locomotives introduced in 1980
Standard gauge locomotives of Czechoslovakia
Standard gauge locomotives of Slovakia
Standard gauge locomotives of the Czech Republic
Škoda locomotives
Bo′Bo′ electric locomotives of Europe


Montrond is a commune in the Hautes-Alpes department in southeastern France.

Population

See also
Communes of the Hautes-Alpes department

References

Communes of Hautes-Alpes


Le Noyer is a commune in the Hautes-Alpes department in southeastern France. With its neighbouring hamlets of Le Serre, Le Martouret and Le Villard, it lies on the banks of the river Drac, close to the Écrins National Park.

Administration

List of mayors
 GAUTHIER Dominique Laurent (1798-1800)
 GAUTHIER Jacques (1800-1815)
 JOUBERT Jean Jacques (1815-1831)
 BERNARD Dominique (1831-1834)
 JOUBERT Jean Jacques (1834-1842)
 BEAUME Philippe (1842-1846)
 GAUTHIER Balthazard (1846-1848)
 DASTREVIGNE Jean Jacques (1848-1865)
 DISDIER Hyppolite (1865-1873)
 BEAUME Philippe (1873-1876)
 FAUQUE Edouard (1876-1886)
 VILLAR Jean Antoine (1886-1891)
 BEAUME Alphonse (1891-1894)
 VILLAR Jean Alexandre (1894-1907)
 DISDIER Hyppolite (1907-1908)
 ROUX Constantin (1908-1912)
 FABRE Joseph (1912-1913)
 ENCOYAND Joseph (1913-1921)
 BEAUME Alphonse (1921-1944)
 BLANC Jean (1944-1945)
 GUILLAUMIER Emile (1945-1947)
 VILLAR Louis (1947-1959)
 FAUQUE Edouard (1959-1989)
 FOUGAIROLLE Jacques (1989-2001)
 LEDUC Jean (2001-2008)
 FOUGAIROLLE Jacques (2008-2014)
 NOUGUIER Renée (2014-2020)
 PY Martine (2014-2020)

Population

See also
Communes of the Hautes-Alpes department

References

Communes of Hautes-Alpes


Regulator of G-protein signaling 6 is a protein that in humans is encoded by the RGS6 gene.

Members of the RGS (regulator of G protein signaling) family have been shown to modulate the functioning of G proteins by activating the intrinsic GTPase activity of the alpha (guanine nucleotide-binding) subunits.[supplied by OMIM]

Interactions

RGS6 has been shown to interact with STMN2 and DMAP1.

References

Further reading


Protein transport protein Sec24C is a protein that in humans is encoded by the SEC24C gene.

Function

The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration. Alternatively spliced transcript variants encoding the same protein have been identified.

Interactions

SEC24C has been shown to interact with SEC23A.

References

Further reading


Poligny () is a commune in the Hautes-Alpes department in southeastern France.

Population

See also
Communes of the Hautes-Alpes department

References

Communes of Hautes-Alpes


Fasciculation and elongation protein zeta-2 is a protein that in humans is encoded by the FEZ2 gene.

This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes zygin II, which can bind to synaptotagmin.

Interactions
FEZ2 has been shown to interact with Protein kinase Mζ.

References

Further reading


Cássio Motta  (born 22 February 1960) is a former professional tennis player from Brazil. He played in the mixed doubles final of the French Open with Cláudia Monteiro in 1982.

Grand Slam mixed doubles finals

Runners-up (1)

Career finals

Doubles (10 wins, 13 losses)

Singles (1 loss)

References

External links

Brazilian male tennis players
Tennis players from São Paulo
Brazilian people of Italian descent
1960 births
Living people


"Highway Chile" ( ) is a song by the Jimi Hendrix Experience, issued as the B-side to their 1967 third British single "The Wind Cries Mary". The song was written by vocalist and guitarist Jimi Hendrix and titled to reflect his pronunciation of "child" without the "d" (a spelling subsequently used for "Voodoo Chile").

Biographers Harry Shapiro and Caesar Glebbeek describe it as "a joyful autobiographical stomp" about the pursuit of the American Dream. Matthew Greenwald of Allmusic feels that the song is autobiographical: "It's easy to see that Hendrix was writing about himself here, and his life as a musician on the road in the R&B/soul 'Chitlin' Circuit', and forming his own unique vision and style." He adds that musically, it is "A funky shuffle... a great place for Hendrix's mid-tempo, R&B riffing, based on a blues pattern."

The song is also included on several Hendrix compilations, such as the UK edition of Smash Hits (1968), War Heroes (1972), and Experience Hendrix: The Best of Jimi Hendrix (1997). The single was mixed in monaural, while a true stereophonic version is included on The Jimi Hendrix Experience box set (2000).

References

1967 songs
The Jimi Hendrix Experience songs
Songs written by Jimi Hendrix
Song recordings produced by Chas Chandler


TV Sports: Basketball is a 1989 computer basketball game for the home computers. It was developed by Cinemaware and published by Mirrorsoft for the Amiga, MS-DOS, Commodore 64 and TurboGrafx-16. It is part of the TV Sports series that included TV Sports: Baseball as well as other games based on hockey and American football.

Cinemaware later re-released the game as freeware.

Gameplay
The game features five-a-side basketball matches. Players can either play against computer (controlling the players or a coach) or with another person (in versus or cooperative mode). When playing the human could choose to control the same player during the whole match or the one currently in possession of the ball.

The game shows a vertical view and has no NBA license. The in-game perspective is from half-court. When the ball crosses half-court, a short cutscene plays showing the players running to the other side of the court as the game transitions to the opposing basket.

Reception
Computer Gaming World said that TV Sports Basketball had good sound and graphics, and favorably noted its four-player option.

In the May 1990 edition of Games International, Mike Siggins complimented the "slick" graphics and arcade/strategy options, but found the manual "inexplicably vague". He concluded by giving the game an above average rating of 8 out of 10 for game play, and an excellent rating of 9 out of 10 for graphics, saying that "it doesn't quite recreate the speed and excitement of a real game. However, there is sufficient variety and structure to make this game worth persevering with. Just don't expect a classic".

References

External links

 Basketball Rules
 TV Sports Basketball at hol.abime.net

1989 video games
DOS games
Amiga games
Commodore 64 games
TurboGrafx-16 games
Basketball video games
Video games developed in the United States
Mirrorsoft games


SH3 and PX domain-containing protein 2A is a protein that in humans is encoded by the SH3PXD2A gene.

References

Further reading


The following article presents a summary of the 1909 football (soccer) season in Brazil, which was the 8th season of competitive football in the country.

Campeonato Paulista

Final Standings

Championship Playoff

AA das Palmeiras declared as the Campeonato Paulista champions.

State championship champions

References

 Brazilian competitions at RSSSF

Seasons in Brazilian football
Brazil


Rochebrune may refer to the following places in France:

 Rochebrune, Hautes-Alpes, a commune in the department of Hautes-Alpes
 Rochebrune, Drôme, a commune in the department of Drôme
 Pic de Rochebrune, a mountain of Cottian Alps
 Pic de Petit Rochebrune, a mountain of Cottian Alps
 Château de Rochebrune, historic castle in Charente, France

Rochebrune can also be a surname:
 Antoine de Rochebrune, French Roman Catholic priest
 Alphonse Trémeau de Rochebrune, French zoologist
 François Rochebrune, French soldier and Polish general who organized the Zouaves of Death
 Octave de Rochebrune (1824-1900), French painter, sculptor and etcher


Protein MICAL-2 is a protein that in humans is encoded by the MICAL2 gene.

References

Further reading


Rochebrune (; ) is a commune in the Hautes-Alpes department in southeastern France.

Population

See also
Communes of the Hautes-Alpes department

References

Communes of Hautes-Alpes


RNA polymerase-associated protein CTR9 homolog is an enzyme that in humans is encoded by the CTR9 gene.

Model organisms
Model organisms have been used in the study of CTR9 function. A conditional knockout mouse line called Ctr9tm1b(EUCOMM)Wtsi was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed:  - In-depth immunological phenotyping

References

External links

Further reading


La Rochette (; ) is a commune in the Hautes-Alpes department in southeastern France. It is located about 10 km north east of Gap.

Population

See also
Communes of the Hautes-Alpes department

References

Communes of Hautes-Alpes


Rousset (; ) is a commune in the Hautes-Alpes department in southeastern France.

Population

See also
Communes of the Hautes-Alpes department

References

Communes of Hautes-Alpes


Opalin is a protein that is encoded in humans by the OPALIN gene.

References

Further reading


Forever... is the debut full-length studio album by the Canadian melodic death metal band Quo Vadis. It was released on April 10, 1996. The last track is taken from the Quo Vadis Demo.

Track listing
All music written by Quo Vadis.

Personnel
Quo Vadis
Arie Itman – guitars, vocals, violin, solo on tracks 1, 7, 8
Bart Frydrychowicz – guitars, vocals, acoustic guitar, solo on tracks 1, 2, 6
Remy Beauchamp – bass
Yanic Bercier – drums, backing vocals

Guest musicians
Corelli - violin on Carpe Deum
Stepehen Henry - scream on "Legions of the Betrayed"
Sebrina Lipari - soprano on track 10

References

1996 debut albums
Quo Vadis (band) albums


Tight junction-associated protein 1 is a protein that in humans is encoded by the TJAP1 gene.

Interactions
TJAP1 has been shown to interact with DLG1.

References

Further reading


Kim Van Hee (born 22 February 1978), better known by her stage name Kim Kay is a Belgian pop singer. She is Flemish, though she is known for delivering vocals in French. Kay took part in the Belgian preselection of the 2002 Eurovision Song Contest with a song called The Sun Shines. Kim Kay's arguably most famous work is her dance single "Lilali", which was a hit in Europe, beyond Belgium and France, where she booked her overall greatest successes throughout her career.

Kay lives in Wichelen and studies psychology in Ghent. In 2004, she was diagnosed with cervical cancer.

Discography

Albums

 La Vie en lilali (1998)
 1. "Lilali"
 2. "Bam bam"
 3. "Le Banana Split"
 4. "Iniminimanimo"
 5. "Donne-moi"
 6. "Oui oh oui"
 7. "Tout simplement"
 8. "Amoureux solitaires"
 9. "À nous"
 10. "99 Luftballons"
 11. "Je danse"
 12. "Poupée de cire, poupée de son" (remix)
 13. "Lilali" (speedgarage mix)
 Hits! (2000)
 1. "Les Sucettes"
 2. "Bam bam"
 3. "Hula hop"
 4. "Poupée de cire, poupée de son"
 5. "Les Vacances d'été"
 6. "Touche à tout"
 7. "Ça plane pour moi"
 8. "Oui oh oui"
 9. "Le Banana Split"
 10. "La Dah-li-danse"
 11. "Iniminimanimo"
 12. "Lilali"
 13. "Bam bam" (speedgarage mix)
 14. "Poupée de cire, poupée de son" (club mix)
 15. "La Dah-li-danse" (dolly family mix)
 16. "Lilali" (mellow mix)

Singles
 "Lilali" (1998)
 "Oui oh oui" (1998)
 "Poupée de cire, poupée de son" (1998)
 "Bam bam" (1999)
 "Iniminimanimo" (1999)
 "La Dah-li-danse" (2000)
 "Les Vacances d'été" (2000)
 "Ça plane pour moi" (2000)
 "Les Sucettes" (2000)
 "Open Your Heart" (2001)
 "Direction le soleil" / "The Sun Shines" (2002)
 "Abracadabrant" (2003)

References

External links
 Unofficial website

1978 births
Living people
People from Dendermonde
People from East Flanders
Eurodance musicians
English-language singers from Belgium
French-language singers of Belgium
EMI Records artists
21st-century Belgian women singers
21st-century Belgian singers


GC-rich sequence DNA-binding factor homolog is a protein that in humans is encoded by the PAXBP1 gene.

Similarity to a transcriptional repressor suggests that this gene's protein product is involved in the regulation of transcription. Alternative splicing of this gene results in three transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.

References

External links

Further reading


Saint-Apollinaire may refer to :

Canada
Saint-Apollinaire, Quebec, a municipality in Quebec

France
Saint-Apollinaire, Hautes-Alpes, a commune in the department of Hautes-Alpes
Saint-Apollinaire, Côte-d'Or, a commune in the department of Côte-d'Or
Saint-Apollinaire-de-Rias, a commune in the department of Ardèche

See also
 Apollinaire (disambiguation)


Saint-Apollinaire (; Vivaro-Alpine: Sant Apolinari) is a commune in the Hautes-Alpes department in southeastern France.

Population

See also
Communes of the Hautes-Alpes department

References

Communes of Hautes-Alpes


William Keith Weigand (born May 23, 1937) is an American prelate of the Roman Catholic Church.  He served as bishop of the Diocese of Sacramento in California from 1993 to 2008. Weigand previously served as the bishop of the Diocese of Salt Lake City in Utah and as a priest in the Diocese of Boise in Idaho.

Biography

Early life
Weigand was born on May 23, 1937, in Bend, Oregon, one of four sons of Harold and Alice Weigand. When Weigand was age 12, the family moved to St. Maries, Idaho.  He attended St. Maries Academy in Cottonwood, Idaho, a school run by the Benedictine Sisters. In 1951, Weigand entered Mt. Angel Minor Seminary in Saint Benedict, Oregon, for secondary school and two years of college.

In 1959, Weigand graduated from St. Edward Seminary in Kenmore, Washington, with a Bachelor of Arts in philosophy. He then attended St. Thomas Seminary in Denver, finishing in 1963 with a Master of Divinity degree.

Priesthood
On May 25, 1963, Weigand was ordained to the priesthood for the Diocese of Boise by Bishop Sylvester W. Treinen at St. Mary Immaculate Church in St. Maries. His first assignment was at Our Lady of Lourdes Parish in Lewiston, Idaho.  However, in 1964, Treinen asked Weigand to serve as vice chancellor of the diocese in Boise.  In 1965, Weigand was named chancellor.

Weigand served as a parochial vicar in several parishes in the diocese, and as the administrator of several missions. Weigand served from 1964 to 1968 as the chancellor and vice-officialis of the diocese, and was a member of the diocesan council of presbyters.

In 1968, Weigand moved to Cali, Colombia, to work at a mission run by the Diocese of Boise. In an interview after his retirement, Weigand described his work in Colombia:“We had a huge challenge to provide religious instruction for youth, to prepare people for Confirmation and marriage. We also established social service ministries that included medical clinics and food pantries. So we had to develop networks of lots of people to help. All these ministries were satellite communities, of sorts, under the umbrella of the parish. It was almost the exact image of a diocese.”  While in Colombia, Weigand started experiencing health issues and requested a return to the United States.  In 1978, he was appointed pastor of St. Hubert's Parish in Homedale, Idaho.

Bishop of Salt Lake City
On September 3, 1980, Pope John Paul II appointed Weigand as bishop of the Diocese of Salt Lake City. He was consecrated on November 17, 1980,by Archbishop John R. Quinn, Bishop Sylvester Treinen and Bishop Joseph Federal at the Salt Palace Convention Center in Salt Lake City.

Soon after becoming bishop, Weigand was diagnosed with primary sclerosing cholangitis, the source of his health issues. However, he was able to continue as bishop. In 1990, Weigand created one of the strongest sexual abuse policies then in effect in the United States.

Weigand led a $9.7 million restoration of the Cathedral of the Madeleine in Salt Lake City from 1991 to 1993. Aside from repairing and cleaning the cathedral, the restoration aimed at bringing it into compliance with liturgical changes resulting from the Second Vatican Council.  The most important change was moving the altar closer to the congregation.

Bishop of Sacramento
On November 18, 1993, Pope John Paul II appointed Weigand as bishop of the Diocese of Sacramento. He was installed January 27, 1994, at the Cathedral of the Blessed Sacrament in Sacramento.

In 1996, Weigand celebrated the funeral mass of former Governor Pat Brown. Then Governor Pete Wilson, previous Governor Jerry Brown, and Sacramento Mayor Joe Serna, Jr. also spoke at the funeral mass. In 2005, as a result of Weigand's primary sclerosing cholangitis, he experienced liver failure.  In April 2005, he received a liver transplant. In October 2007, Father Jaime Soto was named as coadjutor bishop to assist Weigand.

Retirement
In 2008, Weigand submitted a letter of resignation to Pope Benedict XVI due to health issues.  It was granted on November 29, 2008, and on November 30, 2008, Soto succeeded Weigand as bishop of the Diocese of Sacramento.

See also

 Catholic Church hierarchy
 Catholic Church in the United States
 Historical list of the Catholic bishops of the United States
 List of Catholic bishops of the United States
 Lists of patriarchs, archbishops, and bishops

References

External links

 Roman Catholic Diocese of Sacramento official website

Episcopal succession

Roman Catholic bishops of Sacramento
Roman Catholic bishops of Salt Lake City
20th-century Roman Catholic bishops in the United States
21st-century Roman Catholic bishops in the United States
Roman Catholic Diocese of Boise
People from Bend, Oregon
1937 births
Living people
Mount Angel Seminary
Catholics from Oregon


The Walter Byers Scholar (also known as Walter Byers Scholarship, and Walter Byers Postgraduate Scholarship) program is a scholarship program that recognizes the top male and female student-athlete in NCAA sports and that is awarded annually by the National Collegiate Athletic Association (NCAA). It is considered to be the NCAA's highest academic award. The NCAA initiated the Walter Byers Scholarship program in 1988 in recognition of the service of Walter Byers. The award is a postgraduate scholarship program designed to encourage excellence in academic performance by student-athletes. The recipients each year are the one male and one female student-athlete who has combined the best elements of mind and body to achieve national distinction for his or her achievements, and who promises to be a future leader in his or her chosen field of career service. Winners receive scholarships for postgraduate study.

Details
, the stipend for each Byers Scholarship was $24,000 for an academic year. The scholarship amount is adjusted for the cost of living. The grant may be renewed for a second year based on academic progress. Financial need is not a factor in the granting of these scholarships. United States citizenship is not required to satisfy eligibility requirements. Awards from other sources will not disqualify an applicant, except that an awardee may not use more than one NCAA postgraduate scholarship. The Walter Byers Postgraduate Scholarship Program is separate and distinct from the NCAA Postgraduate Scholarship Program, which provides annual awards with smaller stipends.

The five-person Walter Byers Scholarship Committee, established by the NCAA membership and appointed by the NCAA Divisions I, II and III Management Councils, administers the program. The committee membership is required to include at least one man and one woman, at least one member from each division and subdivision of Division I, and one member each from Division II and Division III.

Among the most recognized for post-athletic career accomplishments are Randal Pinkett and Rob Pelinka. Of the winners the one most notable for having gone professional in his or her sport is National Football League veteran Rob Zatechka, who later went on to medical school.

Some winners have won other notable awards.  The following lists dual winners of certain awards:
Rhodes Scholar - Henderson, Thigpen, Pinkett
Top VIII Award - Black, Roethlisberger, Busbee, Carney
NCAA Woman of the Year Award - Black, Bersagel

Winners
The historical winners are as follows:

See also
Academic All-America
List of Academic All-America Team Members of the Year
Elite 89 Award
NCAA Sportsmanship Award (student-athletes who have demonstrated one or more of the ideals of sportsmanship)
Today's Top VIII Award (NCAA) (outstanding senior student-athletes)
NCAA Woman of the Year Award (senior female student-athlete)
Silver Anniversary Awards (NCAA) (former student-athletes)

Notes

External links
Walter Byers Postgraduate Scholarship Program
2007 finalists

NCAA awards
College sports trophies and awards in the United States
Student athlete awards in the United States
Scholarships in the United States
Awards established in 1988